Clinical trials: Men Who Have Sex With Men
Intervention, Control Condition
Adapting An Evidence-Based Intervention To Improve HIV Testing And PrEP Uptake In Vietnam
Young men who have sex with men are experiencing an ongoing HIV epidemic in Vietnam, with an HIV prevalence of 12%. However, HIV testing and pre-exposure prophylaxis (PrEP) use among young men who have sex with men remain low.
- Trial name
- NCT07113626
- Testing
- Mobile app
- Where
- Vietnam
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Hanoi Medical University
Health Behavior
Promoting HIV Self-testing Among MSM During COVID-19 Pandemic
A community-based organization (CBO) recruited Chinese-speaking men who have sex with men who are HIV-negative or unknown sero-status through multiple channels in Hong Kong, China.
- Trial name
- NCT05398835
- Testing
- Online interventions promoting HIV self-testing
- Where
- Hong Kong
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
HIV/AIDS
Evaluation of a Smart Phone App-based Case Management Model Among ART-naive HIV-infected MSM
This is a randomized controlled trial about an app-based case management intervention. The intervention is a comprehensive case management approach consisting of the following aspects: articles delivery, online communication with…
- Trial name
- NCT03860116
- Testing
- APP-based case management service, Standard-of-care followup service
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Sun Yat-sen University
HIV, STI
Feasibility and Impact of Online HIV/STI Screening Addressed to PrEP Users in Spain
Non-blinded randomized controlled non-inferiority trial to evaluate the feasibility, acceptability and impact of an innovative internet-accessed HIV and STIs screening intervention (TÉSTATE PrEP) addressed to gays, bisexuals and…
- Trial name
- TESTATE_PrEP (NCT05752643)
- Testing
- Online follow up
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Fundació Institut Germans Trias i Pujol
HIV Infections
Entre Herman@s: Promoting Health Among Latino MSM
This is a randomized controlled trial with an attention placebo control group. The goal of this study is to decrease HIV incidence in Latino men who have sex with men by engaging their siblings in PrEP-use promotion.
- Trial name
- NCT05805306
- Testing
- Entre Herman@s, Vaccines for Health
- Where
- United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
Pre-exposure Prophylaxis
Information Seeking About Pre-exposure Prophylaxis
The goal of these two intervention studies is to test promising health communication messaging strategies most likely to enhance Black, Hispanic, and non-Hispanic White YMSM's (young men who have sex with men's) engagement with…
- Trial name
- NCT05728034
- Testing
- Injectable PrEP information, Oral PrEP information
- Where
- United States
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Penn State University
Sexually Transmitted Infection (STI) Prevention, Antibiotic Prophylaxis
STI Prophylaxis and Emergence of Antimicrobial Resistance
The goal of this observational study is to understand the risk of antibiotic resistance and changes in the human microbiome (bacteria that live inside and on us), if people use antibiotics to prevent sexually transmitted…
- Conditions
- Sexually Transmitted Infection (STI) Prevention, Antibiotic Prophylaxis, Antibiotic Resistance, Bacterial, Microbiome
- Trial name
- SPEAR (NCT06778083)
- Where
- United Kingdom
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University College, London
Anal Intraepithelial Neoplasia
Biomarkers to Detect Anal Intraepithelial Neoplasia in Thai Men Who Have Sex With Men
The goals of this application are to assess the usefulness of biomarkers, including p16 proteins, minichromosome maintenance (MCM) proteins, high-risk human papillomavirus (HPV) types, and E6 and E7 mRNA/oncoproteins, as adjunct…
- Trial name
- NCT01637298
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
ChemSex Users for YMSM, ChemSex Users
Comprehensive Assessment in a Longitudinal Study on Young Men Who Have Sex With Men Attracting to chemseX
The study is a two-phase observational study that assess multiple aspects of study and young men who have sex with men (YMSM). Phase I of the study will be a cross-sectional descriptive study using a mixed methods data collection…
- Trial name
- CLYMAX (NCT05559658)
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Institute of HIV Research and Innovation Foundation, Thailand
Meningitis, HPV - Anogenital Human Papilloma Virus Infection
Increasing Healthcare Engagement Via Routine Vaccination Among Young Black Men Who Have Sex With Men
Vaccine-preventable diseases such as hepatitis A and meningitis, as well as cancers caused by human papillomavirus (HPV) disproportionately impact young Black men who have sex with men (YBMSM).
- Conditions
- Meningitis, HPV - Anogenital Human Papilloma Virus Infection, Hepatitis A
- Trial name
- NCT03445416
- Testing
- POL arm, Comparison arm
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Tobacco-Related Carcinoma
Evaluating Anti-Tobacco Message Effectiveness Among Lesbian, Gay, Bisexual, and Transgender Young Adults
This trial refines and evaluates anti-tobacco messages among lesbian, gay, bisexual, and transgender (LGBT) young adults at risk for the use of more than one tobacco product (polytobacco use).
- Trial name
- NCT05393869
- Testing
- Health communications
- Where
- United States
- Volunteers
- 2,849 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
HIV, Pre-exposure Prophylaxis
The Development of a Mobile-based App to Increase Uptake of Pre-Exposure Prophylaxis (PrEP) by Men Who Have Sex With Men in China
This study aims to use a mini-application on the popular Chinese social media mobile platform, WeChat, to improve HIV pre-exposure prophylaxis (PrEP) uptake among at-risk men who have sex with men (MSM).
- Trial name
- NCT04426656
- Testing
- Phone application
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Risk Reduction Behavior
HIV Prevention in Very High Risk Men Who Have Sex With Men
The purpose of this study is to pilot test an innovative program development project in an open trial format an 8-session, individual, cognitive-behavioral therapy based, intervention on ten (10) HIV-infected men who have sex…
- Trial name
- ENGAGE (NCT01291589)
- Testing
- Cognitive-behavioral therapy
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Fenway Community Health
HIV Prevention, Substance Use
Host Led Harm Reduction Approach Among Men Who Have Sex With Men Who Engaged in Chemsex in Bangkok, Thailand: A Pre-Implementation Study
This study evaluates the pre-implementation phase of a host-led harm reduction model for men who have sex with men (MSM) engaging in chemsex in Bangkok, Thailand, focusing on understanding harms, contexts, and needs to develop a…
- Conditions
- HIV Prevention, Substance Use, Mental Health, Sexually Transmitted Infections (STIs)
- Trial name
- HAMMOCK (NCT07512869)
- Testing
- Self-administered questionnaire assessment, Semi-structured in-depth interviews (IDIs), Development and refinement of harm reduction model
- Where
- Thailand
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Institute of HIV Research and Innovation Foundation, Thailand
Hepatitis C Virus Infection
Interventions to Curb Hepatitis C Reinfections Among Men Who Have Sex With Men
Men who have sex with men (MSM) who cured from hepatitis C virus (HCV) infection are at substantial risk of HCV reinfection. In this study, the investigators aim to evaluate the effectiveness of an online behavioural…
- Trial name
- ICECREAM (NCT04156945)
- Testing
- Behavioural intervention, HCV RNA home-based test
- Where
- 15 sites in France, Netherlands
- Volunteers
- 258 people
- Sponsor
- Public Health Service of Amsterdam
Psychoactive Substances Consumers
Evaluation of Relationship Between Hypersexuality and Psychostimulant Among Men Who Have Sex With Men
Survey of fifty new psychoactive substances consumers in a context of MTM sexual intercourse. Evaluation using an hetero-assessment questionnaire about the link between hypersexual disorder and the use of synthetic cathinone.
- Trial name
- HYPERCHEM (NCT02969694)
- Testing
- G-STAT questionnaire
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Hospices Civils de Lyon
HIV
Men of African American Legacy Empowering Self
The MAALES Project is a community collaborative intervention designed to prevent HIV infection and transmission among African American men who have sex with both men and women.
- Trial name
- MAALES (NCT01492530)
- Testing
- Men of African American Legacy Empowering Self, Standard HIV Education & Risk Reduction
- Where
- 2 sites in United States
- Volunteers
- 437 people, healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
Risk Behavior
A Small-group Intervention to Reduce HIV Sexual Transmission Risk Behavior Among HIV-positive Men Who Have Sex With Men
Gay Poz Sex (GPS) is an HIV prevention and sexual health promotion program for HIV-positive gay and bisexual men, which takes place in a group counselling format.
- Trial name
- GPS (NCT02546271)
- Testing
- GPS
- Volunteers
- 82 people
- Sponsor
- Toronto Metropolitan University
HIV Preexposure Prophylaxis
Oral Islatravir (MK-8591) Once-Monthly as Preexposure Prophylaxis (PrEP) in Men and Transgender Women Who Are at High Risk for HIV-1 Infection (MK-8591-024)
The main purpose of the study is to evaluate the safety and tolerability of oral Islatravir (ISL) once monthly (QM) as Preexposure Prophylaxis (PrEP) in cisgender men who have sex with men (MSM) and transgender women (TGW) who…
- Trial name
- Impower-024 (NCT04652700)
- Testing
- ISL, FTC/TDF, FTC/TAF
- Where
- 25 sites in United States, Brazil and 5 more
- Volunteers
- 494 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
HIV
Mobile Health Intervention to Increase HIV Testing and Linkage to Care
This 5-year project will test an mobile health approach to improve HIV self-testing (HST) and linkage to HIV-related care among high-risk men in China.
- Trial name
- NCT05484895
- Testing
- WeTest-WeLink, Control condition
- Where
- 3 sites in China
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Emory University