Clinical trials: Meniscus Disorder
Meniscus Tear
The Effect of Therapeutic Exercise on Cartilage Morphology and Physical Function for Individuals at High Risk of Knee Osteoarthritis
This randomized controlled trial aims to evaluate the efficacy of progressive resistance exercises (PRE) versus aerobic exercises on cartilage morphology and physical function in patients with degenerative meniscus tears.
- Trial name
- NCT06532851
- Testing
- Progressive Resistance Exercise (PRE), Aerobic Exercise, Control
- Where
- 2 sites in Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Dry Eye
Analysis of the Diagnostic Performance of LacryDiag, a New Analyzer of the Ocular Surface in the Dry Eye
LacryDiag is a new Conformity European (CE) marked diagnostic imaging device devoted to the analysis of the ocular surface. It is an "all in one" device that provides 4 data: non-invasive break-up time (Non-Invasive Break-Up-Time…
- Trial name
- LACRYMOSA (NCT04093037)
- Testing
- Time #1: Non Invasive Break-Up Time (NIBUT), Time #2: MicroInstillation Break-Up Time (MIBUT) + Oxford score, Time #3: Standard Break-Up Time (SBUT)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Platelets-rich Plasma, Osteoarthritis Knees Both
Effect of Platelet-rich Plasma (PRP) Injection on Knee Osteoarthritis
To evaluate the safety and effectiveness of PRP injection therapy in the repair of osteoarthritis and periarticular soft tissue injury through a single-center, exploratory clinical study, and to provide a more reliable basis for…
- Conditions
- Platelets-rich Plasma, Osteoarthritis Knees Both, Meniscus Disorder, Cartilage Injury
- Trial name
- NCT06082531
- Testing
- Sodium hyaluronate injection
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xijing Hospital
Platelet-Rich Plasma, Knee Injuries
Platelet-rich Plasma for Meniscus Repair
This study aims to evaluate the effect of platelet-rich plasma (PRP) on meniscus injury by comparing the imaging and clinical outcomes between patients receiving PRP with meniscus repair surgery and those receiving meniscus…
- Conditions
- Platelet-Rich Plasma, Knee Injuries, Meniscus Disorder
- Trial name
- NCT03176641
- Testing
- platelet-rich plasma, control
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Pei-Yuan Lee, MD
Tibial Meniscus Injuries, Osteoarthritis, Knee
Autologous, Micro-fragmented Adipose Tissue for Meniscal Tears
The menisci of the knee are essential fibro-cartilaginous structures that contribute in static weight bearing, distributing compressive forces during joint movement, joint lubrication, joint stabilization, and proprioception.
- Trial name
- NCT03714659
- Testing
- Lipogems
- Volunteers
- 20 people
- Sponsor
- New Jersey Regenerative Institute, LLC
Arthritis
Allograft Meniscal Arthroplasty for the Treatment of Basal Joint Arthritis of the Thumb
Hypothesis: The use of knee meniscal allograft as a joint spacer and stabilizer is a viable option for the surgical treatment of basal joint arthritis of the thumb.
- Trial name
- NCT01542515
- Testing
- Meniscal allograft arthroplasty of the carpometacarpal joint of the thumb
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Corewell Health East
Athletic Injuries (C26.857.500.124), Rotator Cuff Injuries
Clinical Outcomes of Arthroscopic Surgeries for Shoulder and Knee Sports Injuries
This observational study aims to evaluate the long-term recovery and clinical outcomes of patients undergoing minimally invasive (arthroscopic) surgeries for sports-related shoulder and knee injuries.
- Conditions
- Athletic Injuries (C26.857.500.124), Rotator Cuff Injuries, Tibial Meniscus Injuries, Shoulder Dislocation or Subluxation
- Trial name
- SK-COHORT (NCT07501013)
- Testing
- Standard of Care Shoulder Arthroscopy, Standard of Care Knee Arthroscopy
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Metabolic Syndrome
Calorie Restricted Diet and Exercise
Calorie-restricted(CR) diet and exercise were effective to reduce Metabolic syndrome(MetS), however, its effect on knee functions for MetS patients with degenerate meniscus lesions(DMLs) was still poorly investigated.
- Trial name
- NCT05092178
- Testing
- calorie restricted diet and exercise, exercise alone
- Where
- China
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- The First People's Hospital of Jingzhou
Osteoarthritis, Meniscus Lesion
A Study on Different Treatments for Knee Osteoarthritis Caused by Damaged Roots of the Medial Meniscus.
Medial meniscus posterior root tears (MMPRT) account for 20% or more of all meniscus tears, but the diagnosis and treatment of this condition continues to plague the general population due to the complexity of the diagnosis and…
- Trial name
- NCT06707948
- Testing
- Arthroscopic meniscus surgery
- Volunteers
- 69 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Osteoarthritis, Knee, Meniscus Tear
Corticosteroid Meniscectomy Randomized Trial
Synovitis has an important role in the symptoms and progression of Osteoarthritis (OA). Inflamed synovium has been associated with both increased symptoms and increased progression in OA patients.
- Conditions
- Osteoarthritis, Knee, Meniscus Tear, Meniscus; Degeneration, Synovitis
- Trial name
- CoMeT (NCT04641351)
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- The Cleveland Clinic
Osteoarthritis of the Knee, Arthroscopy
Development of Knee Osteoarthritis After Arthroscopic Partial Resection of Degenerative Meniscus Tear
It has been previously demonstrated that the risk for the development of knee osteoarthritis is increased after both meniscus tear and meniscectomy.
- Conditions
- Osteoarthritis of the Knee, Arthroscopy, Meniscal Tear
- Trial name
- NCT01052233
- Testing
- Arthroscopic partial meniscectomy, Arthroscopy (diagnostic)
- Where
- 5 sites in Finland
- Volunteers
- 160 people
- Sponsor
- Tampere University
Meniscectomy, Osteoarthritis
The VENUS Clinical Study (Verifying the Effectiveness of the NUsurface® System)
The NUsurface® Meniscus Implant Randomized Study is a multi-center, prospective randomized, interventional clinical trial to test the hypothesis that the NUsurface implant is superior to the non-surgical standard of care in…
- Trial name
- VENUS (NCT02136901)
- Testing
- NUsurface® Meniscus Implant, NSAID's and Non-surgical Treatment Options, Intra-Articular Injections with Corticosteroids
- Where
- 7 sites in Belgium, France and 4 more
- Volunteers
- 34 people
- Sponsor
- Phoenix Kinetics
Meniscus Disorder, Meniscus; Degeneration
Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment
The aim of this study is to assess outcomes of Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment
- Conditions
- Meniscus Disorder, Meniscus; Degeneration, Meniscus Tear, Meniscus Lesion
- Trial name
- NCT05882591
- Testing
- Posteromedial Tibiofemoral Incongruence (PMTFI) Treatment by the means of published technique (reference nr 1).
- Where
- Poland
- Volunteers
- 10 people
- Sponsor
- Artromedical Konrad Malinowski Clinic
Meniscus Tear, Meniscus Disorder
Clinical Outcomes, Graft Longevity, and Chondral Protection Following Primary or Revision Meniscal Allograft Transplantation Surgery
The MERCuRE (MEniscus, REstoration, Conservation, and Repair) group is embarking on a 20-year follow-up study to evaluate the clinical outcomes, graft longevity, and chondral protection following primary or revision Meniscal…
- Conditions
- Meniscus Tear, Meniscus Disorder, Patient Satisfaction
- Trial name
- NCT06749431
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Joint Restoration Foundation, Inc.
Meniscal Tear, Chondromalacia
The ChAMP (Chondral Lesions And Meniscus Procedures) Trial
The purpose of this randomized controlled trial is to determine the effectiveness of treating cartilage lesions found during knee arthroscopy.
- Trial name
- NCT01527201
- Testing
- Arthroscopic debridement
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- State University of New York at Buffalo
Knee Osteoarthritis, Meniscus Disorder
Evaluation of Meniscal Extrusion by Dynamic Ultrasonography in Patients With Ostearthritis
This is a diagnostic, open-label, single-center interventional study. The aim of the study is to evaluate the relationship between medial and lateral meniscus extrusion determined by dynamic ultrasound study and bone edema…
- Trial name
- NCT06113536
- Testing
- Ultrasonographic evaluation
- Where
- Italy
- Volunteers
- 202 people
- Sponsor
- Istituto Ortopedico Rizzoli
Meniscus; Degeneration, Osteoarthritis, Knee
Treatment of the Medial Meniscus With the NUsurface(R) Meniscus Implant
This is a prospective, multi-center, open label, non-randomized study, evaluating the treating of medial meniscus deficiency with the NUsurface Meniscus Implant.
- Trial name
- NCT01712191
- Testing
- NUsurface Meniscus Implant
- Where
- 10 sites in Belgium, Germany and 4 more
- Volunteers
- 128 people
- Sponsor
- Phoenix Kinetics
Gonarthrosis, Meniscus; Degeneration
Comparison of Ultrasound-Guided Perimeniscal Steroid and 5% Dextrose Injections in Knee Osteoarthritis
Introduction: The primary goal of treating knee osteoarthritis is to reduce pain and improve the patient's quality of life. Medial meniscal extrusion is a condition that is linked to pain and disability in knee osteoarthritis and…
- Conditions
- Gonarthrosis, Meniscus; Degeneration, Pain, Chronic
- Trial name
- NCT06308887
- Testing
- Triamcinolone Acetonide, Dextrose 5% in water
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Kastamonu University
Dry Eye
Diurnal Variation of Tear Meniscus and Tear Osmolarity
This study is to determine the diurnal variation of tear meniscus and tear osmolarity in normal subjects and dry eye patients.
- Trial name
- NCT01206244
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Miami
Patellar Dislocation, ACL Injury
The Faroese Knee Cohort: Etiology and Long-term Implications of Trochlear Dysplasia and Patellar Dislocations.
The investigators intend to establish a national cohort including all persons in the ages from 15-20 years old with patellar instability (PI) or a prior knee injury (ACL-ruptur or meniscus damage) .
- Conditions
- Patellar Dislocation, ACL Injury, Meniscus Lesion, Trochlear Dysplasia
- Trial name
- FKC (NCT04607538)
- Testing
- No intervention is made
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital