Clinical trials: Menopausal
Menopause Syndrome
Effects of Connective Tissue Manipulation on Menopausal Symptoms
Menopause is defined as the permanent cessation of menstruation as a result of the loss of ovarian follicular function. This process involves some bothersome physical and psychological climacteric symptoms.
- Trial name
- NCT05293860
- Testing
- Connective tissue manipulation, Superficial massage with the head of the therapeutic ultrasound device
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Hacettepe University
Post Menopausal, Resistance Exercise
Feasibility of Lower-Body EMS Resistance Training in Postmenopausal Women
This pilot randomized controlled trial evaluates whether combining lower-body electrical muscle stimulation (EMS) with resistance training is feasible and beneficial for physically inactive postmenopausal women, who experience…
- Conditions
- Post Menopausal, Resistance Exercise, Body Composition, Autonomic Function
- Trial name
- LB-EMS-Pilot (NCT07628790)
- Testing
- Lower-Body EMS combined with Resistance Training, Resistance Training
- Where
- South Korea
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Seoul National University
Menopausal Complaints
Evaluation of the Relationship Between Mediterranean Diet and Menopausal Symptoms in Postmenopausal Women
This cross-sectional study aimed to evaluate the relationship between the frequency and severity of postmenopausal symptoms in women aged 45-65 years and the level of compliance with the Mediterranean diet, and the main question…
- Trial name
- NCT06755255
- Where
- Turkey (Türkiye)
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Breast Cancer
Study of Moderate Dose Omega 3 Fatty Acid Supplement in Premenopausal Women at High Risk for Breast Cancer
This pilot study is an investigation of feasibility of moderate dose omega-3 fatty acid supplementation in pre-menopausal women at high risk for breast cancer who are considering future pregnancy.
- Trial name
- NCT03383835
- Testing
- Omega-3 Supplementation
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Lauren Nye
Menopausal Symptoms
Efficacy of CL22205 on Bone Mineral Density and Menopausal Symptoms
The purpose of this study is to evaluate the effect of CL22205 on bone mineral density and menopausal symptoms in women.
- Trial name
- NCT06899243
- Testing
- CL22205
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Eetho Brands, Inc
Alopecia
Topical AS101 for Treatment of FAGA (Female Androgenetic Alopecia) in Menopause Women
The primary objective of this study is to assess the safety and efficacy of topical AS101 as treatment for Female Androgenetic Alopecia (FAGA) in menopause women.
- Trial name
- NCT00418249
- Testing
- AS101
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Rabin Medical Center
Perimenopause, Menopause
Our Transitions: Improving the Path to Menopause With Personal Digital Health Technologies
The goal of this observational study is to build knowledge about the path to menopause using subjective, self-reported and objectively measured information from multiple wearable study devices and a smartphone app.
- Trial name
- NCT07597915
- Volunteers
- 1,250 people
- Sponsor
- 4YouandMe
Post Menopausal Breast Cancer
Study in Post-menopausal Women With Hormone Receptor Positive, HER2-negative Advanced Breast Cancer
This international, multi-center, open-label, single-arm study evaluated the safety and tolerability profile of everolimus in post-menopausal women with HR positive, HER2 negative locally advanced or metastatic breast cancer…
- Trial name
- EVEREXES (NCT03176238)
- Testing
- everolimus, exemestane
- Where
- 55 sites in Australia, India and 11 more
- Volunteers
- 235 people
- Sponsor
- Novartis Pharmaceuticals
Obesity, Menopausal Syndrome
Regulation of Cortisol Metabolism and Fat Patterning
The purpose of this study is to determine if estrogen or testosterone can affect cortisol levels and where fat builds up in our bodies.
- Trial name
- NCT00694733
- Testing
- Depo Lupron/Aromatase inhibitor, Estrogen cream
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Diabete Type 2
Vascular and Metabolic Changes in Postmenopausal Diabetics
The presence of type 2 diabetes mellitus (T2DM) also increases the relative risk of developing cardiovascular disease in women compared to men.
- Trial name
- NCT03273738
- Testing
- folate level measurement, B12
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Nursing Caries, Surgical Menopause
The Effect of Nursing Support Program for Women in Surgical Menopause on Their Life Quality
Objective: The aim of this study was to determine the effect of the nursing support program developed in line with the Roy Adaptation Model on the quality of life, sleep quality and depressive symptom status of women in surgical…
- Conditions
- Nursing Caries, Surgical Menopause, Quality of Life
- Trial name
- NCT05809960
- Testing
- Nursing support program, Routine nursing care
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Mehtap Gümüşay
Atrophy, Vaginal Diseases
A Clinical Study to Evaluate the Safety of Ospemifene
The purpose of this study is to determine the efficacy and long-term safety of 60mg ospemifene in the treatment of VVA in postmenopausal women with intact uterus.
- Trial name
- NCT00566982
- Testing
- Ospemifene 60 mg
- Volunteers
- 426 people
- Sponsor
- Shionogi
Menopause, Dyspareunia
Multi-point Intra-mucosal Injections of Cross-linked Hyaluronic Acid (DESIRIAL®) in the Vaginal Vestibule
The main objective of this study is to measure changes in the thickness of the vaginal lining (epithelium + underlying stroma) between 0 and 8 weeks after injection.
- Trial name
- INREG 1 (NCT02739880)
- Testing
- DESIRIAL® (Intra-mucosal Injections of Cross-linked Hyaluronic Acid)
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Coronary Artery Disease, Genetic Predisposition to Disease
Genetic Risk Stratification for Primary Prevention of CAD in Men and Pre & Post-menopausal Women
The investigators propose to genotype males and females at age 40 years and older, who are asymptomatic and without known heart disease (N=2000).
- Trial name
- NCT05169840
- Testing
- Genetic Risk Score for Coronary Artery Disease
- Where
- 3 sites in United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Sleep Initiation and Maintenance Disorders, Menopause
Chinese Herbal Sachet Therapy for Sleep Quality in Menopausal Women
Many women sleep poorly during the menopausal transition. Some prefer not to take hormone therapy or sleeping tablets, and ask their nurses about other options.
- Trial name
- NCT07757724
- Testing
- Traditional Chinese medicine aromatic sachet
- Where
- Macau
- Volunteers
- 122 people
- Sponsor
- Macao Polytechnic University
Low Back Pain, Neck Pain
How Does Basic Body Awareness Therapy Effect Pain Coping Strategies in Postmenopausal Women?
Exercise interventions are deemed essential for the effective management of patients with pain. Various therapy methods have been shown in the literature for pain and coping with pain.
- Conditions
- Low Back Pain, Neck Pain, Menopause
- Trial name
- NCT05893290
- Testing
- Therapeutic Exercise Group, Therapeutic Exercise+Basic Body Awareness Therapy Group
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- European University of Lefke
Serum CNP Levels, Healthy Reproductive Age Women
Serum Levels of C Type Natriuretic Peptide in Different Reproductive Periods
Recent studies have shown that C natriuretic peptide (CNP) is produced from granulosa cells, increasing cumulative guanosine monophosphate (cGMP) production by affecting cumulus cells through natriuretic peptide receptors.It has…
- Conditions
- Serum CNP Levels, Healthy Reproductive Age Women, Healthy Perimenopausal Women, Healthy Postmenopausal Women
- Trial name
- CO (NCT04000815)
- Testing
- C Type Natriüretic Peptide
- Where
- Cyprus
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
Menopausal Hot Flashes
Effect of IMB Model-Based Education for Women With Menopausal Hot Flashes
This study was conducted to examine the effect of an education program based on the Information-Motivation-Behavioral Skills (IMB) Model on the level of hot flashes, overall menopausal symptoms, and quality of life in women…
- Trial name
- IMB (NCT07407907)
- Testing
- IMB Model-Based Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Marmara University
Menopause, Aging
Role of Menopause in Thermoregulation
The frequency and severity of heat waves has increased in the last decades. Older adults (over 65 years) have impaired responses to heat stress making them at increased risk for adverse events.
- Trial name
- NCT06798571
- Testing
- Elagolix Oral Tablet, Estradiol patch
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Penn State University
Menopause, Exercise
Ambulatory and Blood Pressure Variability Responses to Exercise in Normotensive and Hypertensive Women
This study evaluated the differences between normotensive and hypertensive menopausal women in ambulatory and blood pressure variability responses to combined aerobic and resistance exercise.
- Conditions
- Menopause, Exercise, Blood Pressure, High
- Trial name
- NCT03531034
- Testing
- Combined Exercise Training
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
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