Clinical trials: Menopausal
Genitourinary Syndrome of Menopause
Non-ablative Diode Laser Therapy for Genitourinary Syndrome of Menopause: A Prospective Study on Efficacy, Safety, and Quality of Life and Sexuality Impact
The goal of this observational study is to evaluate the efficacy, safety, and impact on quality of life and sexuality of non-ablative dual-wavelength diode laser treatments in managing Genitourinary Syndrome of Menopause (GSM) in…
- Trial name
- GSMLASER (NCT06503003)
- Testing
- Leonardo® Diode laser
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University of Cagliari
Pre-Diabetic
Effect of 1,25-dihydroxyvitamin D3, Treatment on Insulin Secretion and Muscle Strength in Pre-diabetic Persons
The purpose of this research is to study the effects of 1,25(OH)2 D3 (a prescription form of active Vitamin D) on muscle strength and insulin secretion by the pancreas and glucose utilization by skeletal muscle.
- Trial name
- NCT04286529
- Testing
- Calcitriol capsules
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Breast Cancer, Insulin Resistance
Insulin Resistance and Breast Cancer
This study will characterize risk factors associated with breast cancer development in some patients. In particular, it will examine the role of insulin in breast cancer in patients with and without a family history of the…
- Trial name
- NCT00304941
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Stage IV Non-small Cell Lung Cancer
Exemestane, Pemetrexed Disodium, and Carboplatin in Treating Post-Menopausal Women With Stage IV Non-Small Cell Lung Cancer
This phase I trial studies the side effects and best dose of exemestane in combination with pemetrexed disodium and carboplatin in treating post-menopausal women with stage IV non-small cell lung cancer.
- Trial name
- NCT01664754
- Testing
- exemestane, pemetrexed disodium, carboplatin
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Walking, Sleep
The Effect of Walking Exercise on Sleep Quality in Sedentary Healthy Adults
The primary goal of this study is to examine the effect of one-hour walking exercise on sleep quality in adults. The second goal of this study is to explore a feasible exercise method to promote sleep quality to all age groups…
- Conditions
- Walking, Sleep, Stress, Psychological, Lifestyle, Sedentary
- Trial name
- NCT04427696
- Testing
- Aerobic walking intervention
- Where
- Hungary
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Feifei Wang
Vasomotor Symptoms
A Study of Fezolinetant to Treat Hot Flashes in Women Going Through Menopause
This study is for women in menopause who have moderate to severe hot flashes. It is for women who are unable to use hormone replacement therapy (HRT). Menopause, a normal part of life, is the time after a woman's last period.
- Trial name
- Daylight (NCT05033886)
- Testing
- fezolinetant
- Where
- 69 sites in Belgium, Canada and 14 more
- Volunteers
- 453 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Urinary Incontinence,Stress
Knack Technique in Post-menopausal Women With Stress Urinary Incontinence
To determine the Effects of pelvic floor muscle exercise with and without Knack Technique in post-menopausal women with stress urinary incontinence
- Trial name
- NCT05751213
- Testing
- knack technique., pelvic floor muscle exercises
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cardiovascular Diseases, Diabetes
The Flamenco (Fitness League Against MENopause COsts) Project
Spain is the second country in the world that consume more drugs. The average drug expenditure per capita in Andalucía during 2011 was 219.2 €. This drug spending increases during the perimenopausal period.
- Conditions
- Cardiovascular Diseases, Diabetes, Dyslipidemias, Metabolic Syndrome
- Trial name
- FLAMENCO (NCT02358109)
- Testing
- exercise
- Where
- Spain
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Osteoporosis, Postmenopausal
A Study of 2 Different Formulations of Blosozumab (LY2541546) in Post Menopausal Women
The purpose of this study is to evaluate the tolerability of two different formulations of blosozumab in women who have reached menopause. This study will last approximately 12 weeks for each participant, not including screening.
- Trial name
- NCT02337387
- Testing
- Blosozumab
- Where
- 3 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Cognitive Impairment, Executive Dysfunction
Vascular Mechanisms for the Effects of Loss of Ovarian Hormone Function on Cognition in Women
Complaints about memory and thinking are common in women as they go through menopause and estrogen levels fall. The ovarian hormone estrogen is important for supporting normal cognitive function, and changes in brain activity and…
- Conditions
- Cognitive Impairment, Executive Dysfunction, Endothelial Dysfunction, Cardiovascular Disease
- Trial name
- NCT02122198
- Testing
- Leuprolide acetate, Estradiol, Medroxyprogesterone
- Where
- 2 sites in United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Menopausal, Perimenopause
Creatine HCl and Creatine Ethyl Ester Supplementation in Perimenopausal and Menopausal Women
The goal of this randomized controlled double-blind parallel-group interventional trial is to evaluate the effects of of dietary supplementation with creatine HCl and creatine ethyl ester supplementation on cognitive performance…
- Trial name
- CONCRET-MENOPA (NCT06660004)
- Testing
- Dietary Supplement: Experimental 1 Creatine HCl, Dietary Supplement: Experimental 2 Creatine HCl, Dietary Supplement: Experimental 3 Creatine Ethyl ester
- Where
- Serbia
- Volunteers
- 36 people
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Menopause, Hormone Replacement Therapy
Effects of Hormone Replacement Therapy on Cardiovascular Risk and Body Composition Parameters
Menopause is defined as the last episode of menstrual bleeding, resulting from the interruption of ovarian function by follicular depletion.
- Trial name
- NCT04453332
- Testing
- Oral hormone therapy (estradiol and micronized natural progesterone), Non-oral hormone therapy (estradiol and micronized natural progesterone)
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Turner Syndrome, Infertility, Female
Turner Syndrome Minipuberty Study
Rationale: Due to accelerated germ cell loss, infertility is a major problem in girls with Turner syndrome (TS). Therefore, cryopreservation of ovarian tissue or oocytes before exhaustion of the ovarian reserve may preserve…
- Conditions
- Turner Syndrome, Infertility, Female, Premature Ovarian Failure, Gonadal Dysgenesis
- Trial name
- Minipuberty (NCT04189406)
- Testing
- Venapunction
- Where
- 13 sites in Denmark, Germany and 3 more
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Hypertension, Menopause
Effects of Different Exercises Interventions in Post-menopausal Women
This study will compare different exercise training protocols on health parameters of postmenopausal women. The hypothesis is that short duration high intensity interval training will promote different effects of long duration…
- Trial name
- NCT03942276
- Testing
- High intensity interval training, Moderate intensity continuous training, Control
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of Uberlandia
Breast Cancer Female, Genitourinary Syndrome of Menopause
MonaLisa Laser Intervention for Post-Menopausal Breast Cancer Patients: A SHE CAN Study
The purpose of this study is to assess the efficacy of a fractional CO2 laser ("SmartXide2 - V2LR", DEKA M.E.L.A., Florence - Italy) "the Laser" in the treatment of genitourinary symptoms of menopause, female sexual function, and…
- Trial name
- NCT04606550
- Testing
- Microablative Fractional CO2 Laser Therapy
- Sponsor
- Mount Sinai Hospital, Canada
Infertility
MENOPUR® Versus FOLLISTIM®
To compare the efficacy and safety of highly purified menotropin (Menopur®) with that of follitropin beta (FOLLISTIM®) in patients who are undergoing gonadotropin-releasing hormone (GnRH) antagonist in vitro fertilization (IVF)…
- Trial name
- NCT00802360
- Testing
- Menotropin, Progestrone vaginal insert, follitropin beta
- Where
- 7 sites in United States
- Volunteers
- 173 people
- Sponsor
- Ferring Pharmaceuticals
Genitourinary Syndrome of Menopause (GSM), Bacterial Vaginosis
Photobiomodulation for Vaginal Dysfunctions: Home-Based vs Outpatient Treatment
Vaginal disorders, including vulvovaginal candidiasis (VVC), bacterial vaginosis (BV), and genitourinary syndrome of menopause (GSM), are highly prevalent conditions that significantly affect women's quality of life and sexual…
- Conditions
- Genitourinary Syndrome of Menopause (GSM), Bacterial Vaginosis, Vulvovaginal Candidiasis (VVC)
- Trial name
- NCT07697768
- Testing
- Blue LED Photobiomodulation
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- Patricia Lordelo
Vasomotor Symptoms
Effect of Yoga on Objective and Subjective Menopausal Hot Flashes
The purpose of this research study is to compare yoga and health and wellness classes for helping perimenopausal or newly postmenopausal women who are experiencing hot flashes.
- Trial name
- GLAM (NCT01073397)
- Testing
- Yoga
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Perimenopause
Hemodynamics After Resistance Training
Women's blood vessel health gets worse after menopause, or "the change of life". Some women exercise less during menopause. Exercise can improve blood vessel health.
- Trial name
- HeART (NCT07022340)
- Testing
- Resistance Training Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Urinary Tract Infections
Impact of Cranberry Juice Consumption on Gut and Vaginal Microbiota in Post-menopausal Women
This study was a randomized, placebo-controlled, crossover, pilot dietary intervention. Ocean Spray Cranberries, Inc provided the experimental and placebo beverages, which have been validated and used in previous studies [26-29].
- Trial name
- NCT04680325
- Testing
- Juice daily consumption
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Arkansas, Fayetteville
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