Clinical trials: Menopausal
Fatigue
Radicle Women's HealthTM: A Study Assessing the Impact of Health and Wellness Products on Fatigue and Related Health Outcomes Among Women Experiencing Menopausal Symptoms
Radicle Women's HealthTM: A randomized, double-blind, placebo- controlled direct-to-consumer study assessing the impact of health and wellness products on fatigue and related health outcomes among women experiencing menopausal…
- Trial name
- NCT07572578
- Testing
- Fatigue Active Product 1
- Where
- United States
- Volunteers
- 502 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Primary Ovarian Insufficiency, Premature Menopause
Injections of Autologous PRP in Women With Primary Ovarian Insufficiency
Premature ovarian failure is a loss of normal function before age 40, leading to infertility and hypoestrogenism. This study will involve only adult women with a diagnosis of POI.
- Trial name
- PRP4POI (NCT03542708)
- Testing
- A-PRP
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Center for Human Reproduction
Breast Cancer
To Compare ZOLADEX 10.8 mg With ZOLADEX 3.6mg in Chinese Pre-menopausal ER+ HER2- Early Breast Cancer.
This study will recruit 168 patients in approximately 20 study centres in China. The primary objective of this study is to examine whether ZOLADEX 10.8 mg depot is non-inferior to ZOLADEX 3.6 mg depot in terms of the suppression…
- Trial name
- LARES (NCT03658213)
- Testing
- ZOLADEX 10.8 mg, ZOLADEX 3.6mg
- Where
- 11 sites in China
- Sponsor
- AstraZeneca
Sleep Quality, Menopause
Effect of ZenRest™ Lotus Seed & Rice Germ Extract Blend on Sleep Quality in Menopausal Women
The goal of this clinical trial is to learn if ZenRest™ (Lotus Seed \& Rice Germ Extract Blend) can help improve sleep quality in menopausal women aged 40-65 with mild-to-moderate sleep complaints.
- Trial name
- NCT07678359
- Testing
- Lotus Seed & Rice Germ Extract
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nutraland USA, Inc.
Menopausal Syndrome
The Effect of Internet- and Mobile-based Group Treatment in Menopausal Women
Background: Menopause syndrome generally occurs with and is related to psychological problems. However, Internet- and mobile-based group treatment (imGT) may improve women's physiological and psychological conditions.
- Trial name
- IMGTMP (NCT03948269)
- Testing
- group behavioral cognitive therapy
- Where
- China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Southeast University, China
Menopause
Getting Under the Skin of the Menopausal Hot Flush
The aim of this research is to 1) test how the skin blood vessels and sweat glands function in women who experience hot flushes by using skin microdialysis to deliver small amounts of substances to the skin that cause increased…
- Trial name
- NCT06222073
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Postmenopausal Symptoms
The Effects of Isoflavone and Estrogen in Sex Response in Climacteric Women
Climacterium is marked by hypoestrogenism and it is associated to drastic vasomotors symptoms, genital atrophy and humor alteration. Additionally, these symptoms impair sexual life and life quality.
- Trial name
- NCT00905723
- Testing
- estradiol, isoflavone
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Secondary Hyperparathyroidism, End Stage Renal Failure
Quality of Life Change in Patients Undergoing Parathyroidectomy With End-stage Renal Failure
The purpose of this study is to characterize the quality of life change in patients undergoing parathyroidectomy with secondary hyperparathyroidism due to end-stage renal failure.
- Trial name
- NCT06378931
- Testing
- Quality of life progression after parathyroidectomy
- Volunteers
- 80 people
- Sponsor
- Chunling Jiang
Sarcopenia, Falls Patient
Sarcopenia and Risk of Fall in Osteoporotic Postmenopausal Women
The main scope of the present pilot study is to evaluate the possible association between the status of sarcopenia and the risk of fall in osteoporotic postmenopausal women.
- Conditions
- Sarcopenia, Falls Patient, Osteoporosis, Postmenopausal
- Trial name
- Sarcopenia (NCT03382366)
- Testing
- Blood sampling, risk of fall evaluation, and MR acquisition.
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Menopause
Effect of Red Clover on Menopause Symptoms and Lipid Profile
The goal of this clinical trial is to investigate the effects of red clover isoflavones on menopausal symptoms and lipid profile in menopausal females.This prospective randomized, double-blind, placebo-controlled study included…
- Trial name
- NCT06209697
- Testing
- red clover
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Medipol University
Bone Loss, Age Realted, Post Menopausal
Flaxseed Consumption and Bone Metabolism in Postmenopausal Women.
This proposed randomized double blinded, placebo-controlled, parallel trial; with two arms, in females aged 50-70 years, volunteers will be postmenopausal with a BMI between 25-35 kg/m2.
- Trial name
- FLAX (NCT03036722)
- Testing
- Flaxseed
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Reading
Postmenopausal Atrophic Vaginitis, Postmenopausal Symptoms
LASER and Radiofrequency and Genitourinary Syndrome of Menopause
This is a randomized controlled trial to evaluate the use of LASER, Micro Ablative radiofrequency and topic strogen to treat symptoms of vulvovaginal atrophy of post menopause.
- Conditions
- Postmenopausal Atrophic Vaginitis, Postmenopausal Symptoms, Genitourinary Symptoms
- Trial name
- EPMLARF-arm1 (NCT04045379)
- Testing
- LASER, Microablative Radiofrequency, Estriol
- Where
- Brazil
- Volunteers
- 195 people
- Sponsor
- Federal University of São Paulo
Pancreatic Cancer
A Study of the Life Changes Experienced by Patients With Pancreatic Cancer
The purpose of this study is to better understand what types of transitions people with pancreatic cancer face when they receive chemotherapy.
- Trial name
- NCT04427761
- Testing
- Measurement of Transitions in Cancer Scale (MOT-CA) Survey, Distress Thermometer Survey
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Perimenopausal Disorder, Menopause
Inovium Ovarian Rejuvenation Trials
The Inovium Ovarian Rejuvenation Treatment is a PRP-based autologous treatment used in combination with a stimulated IVF sequence and Pre-Implantation Genetic Screening to treat infertility in women experiencing menopause…
- Conditions
- Perimenopausal Disorder, Menopause, Menopause, Premature, Menopause Related Conditions
- Trial name
- NCT03178695
- Testing
- Autologous PRP injection into human ovarian tissue
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ascendance Biomedical
Menopause Syndrome
The Benefits and Risks of Different Menopausal Hormone Replacement Therapy Regimes in the Treatment of Menopause Syndrome
A prospective, open-label, randomized controlled clinical trial to compare the benefits and risks of half-dose or standard-dose conjugated equine estrogens(CEE) plus natural progesterone or dydrogesterone in menopausal hormone…
- Trial name
- NCT03436303
- Testing
- CEE 0.625 mg/MP 100mg, CEE 0.3 mg/MP 100mg, CEE 0.625mg/dydrogesterone
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Vulvovaginal Atrophy, Menopause
Vulvovaginal Atrophy Questionnaire (VVAQ): Psychometric Validation of a Novel PROM
The goal of this study is to perform a quantitative assessment of the psychometric properties of the Vulvovaginal Atrophy Questionnaire (VVAQ), a novel patient reported outcome measure (PROM), through a REDCap survey of…
- Conditions
- Vulvovaginal Atrophy, Menopause, Genitourinary Syndrome of Menopause
- Trial name
- NCT04746456
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Massachusetts General Hospital
Schizophrenia, Schizoaffective Disorder
Raloxifene in Treatment of Schizophrenia and Schizoaffective Disorder
The objective of the study is to evaluate the efficacy of raloxifene compared to placebo, as add-on to anti-psychotics in the treatment of post menopausal patients with schizophrenia.
- Trial name
- RAL-S-01 (NCT01280305)
- Testing
- raloxifene
- Where
- 13 sites in Israel, Romania
- Volunteers
- 200 people
- Sponsor
- Sheba Medical Center
Breast Cancer Female
Letrozole in Post-Menopausal Patients With Operable Hormone-Sensitive Breast Cancer
A short pre-surgical non-therapeutic trial involving postmenopausal women with newly diagnosed eR+, HeR2-negative operable breast cancers.
- Trial name
- NCT03747042
- Testing
- Letrozole
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Texas Southwestern Medical Center
Climacteric Symptoms
China Cimicifuga Trial of Climacteric Complaint Control
This study is designed to determine whether an extract of Cimicifuga Foetida L. is safe and efficacious to relieve the climacteric symptoms of Chinese women
- Trial name
- CCCCC (NCT00622986)
- Testing
- an extract of Cimicifuga Foetida L.
- Where
- 13 sites in China
- Volunteers
- 288 people
- Sponsor
- Shandong Luye Pharmaceutical Co., Ltd.
Menopause, Hypertension
Pituitary Derived-Intermedin is an Estrogen-Modulated Factor for Reducing Blood Pressure
Calcitonin, calcitonin gene-related peptides (CGRPs), adrenomedullin, and amylin belong to a unique group of peptide hormones important for the regulation of calcium balance, neurotransmission, cardiovascular homeostasis, and…
- Trial name
- NCT00133783
- Testing
- intermedin
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
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