Clinical trials: Menopausal
State; Climacteric
Integrative Health Care Model for Climacteric Stage Women
Background: Climacteric stage women experience significant biological, psychological and social changes. With demographic changes being observed in the growing number of climacteric stage women in Mexico, it is important to…
- Trial name
- IHCM (NCT01272115)
- Testing
- Integrative health care model
- Where
- Mexico
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Post Menopausal, Hormone Receptor Positive Breast Cancer
A Phase 1b Study of TAK-700 in Postmenopausal Women With Hormone-receptor Positive Metastatic Breast Cancer
In this study the investigators want to find out about the effects of this drug in women with metastatic breast cancer. The study has two major parts; dose escalation and dose expansion.
- Trial name
- NCT01808040
- Testing
- TAK700
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Wisconsin, Madison
Sleep Disturbance
Kneipp Water Applications for Insomnia
The purpose of this study is to ascertain whether warm footbathes are effective on sleep disturbances in women before climacteric.
- Trial name
- KWAI (NCT03114189)
- Testing
- footbath, care of sleep
- Where
- Germany
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universität Duisburg-Essen
Premature Ovarian Failure
Endocan Levels in Women With Premature Ovarian Insufficiency
Objective: To evaluate serum endocan levels in women with premature ovarian insufficiency (POI) and to compare the results with those of healthy subjects.
- Trial name
- Endocan&POI (NCT03924648)
- Testing
- Endocan levels
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Cengiz Gokcek Women's and Children's Hospital
HDL Cholesterol
High-density Lipoprotein (HDL) Cholesterol in Women Taking Tibolone
Tibolone (Livial) has been shown in previous studies to lower HDL cholesterol by up to 40%. This study aims to study the effects of fenofibrate on HDL and subfractions in women taking tibolone.
- Trial name
- TibFen (NCT00809068)
- Testing
- fenofibrate and tibolone, tibolone
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Keogh Institute for Medical Research
Bone Loss, Post Menopausal Osteoporosis
Lactobacillus Acidophilus and Postmenopausal Women
This study aims to evaluate the effect of Lactobacillus acidophilus supplementation on calcium status and bone densitometry in postmenopausal women in a randomized, double-blind placebo-controlled study.
- Conditions
- Bone Loss, Post Menopausal Osteoporosis, Mineralization
- Trial name
- LaBon (NCT05332626)
- Testing
- Probiotic group
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Life Sciences
Hypoactive Sexual Desire Disorder
An Open-Label Study of 50 Mg Oral Testosterone Undecanoate (Kyztrex) in Menopausal Women with Low Testosterone and HSDD
This is an unblinded study to be conducted at a single research center, San Diego Sexual Medicine. Eligible subjects will receive 50 mg capsules of Kyzatrax® to be taken orally daily over a 3-month period.
- Trial name
- NCT06082817
- Testing
- Oral Testosterone Undecanoate
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- San Diego Sexual Medicine
Edema, Depression
Safety and Efficacy Study of Gamaline+Hipericin in PMS
GAMALINE is already register for PMS and HIPERICIN as antidepressive drug. Both plant extracts. The investigators will try the mixture and see if the vasomotor symptoms will disappear.
- Conditions
- Edema, Depression, Hot Flashes, Anxiety
- Trial name
- GH (NCT01283568)
- Where
- Brazil
- Volunteers
- 240 people
- Sponsor
- Phytopharm Consulting Brazil
Climacteric Symptoms, Breast Cancer Survivors
Internet-based Cognitive Behavioral Therapy for Breast Cancer Patients With Climacteric Symptoms
The current study will evaluate systematically the efficacy and cost-effectiveness of two internet-based CBT/relaxation programs (one guided, the other self-managed) in reducing the severity of menopausal symptoms and improving…
- Trial name
- NCT02672189
- Testing
- EVA-Online
- Where
- Netherlands
- Volunteers
- 254 people
- Sponsor
- The Netherlands Cancer Institute
Nocturia, Menopause
Hormonal Influences on Diuresis
The aim of this study was to observe the effect of hormonal treatment (oral or transdermal substitution therapy) on diuresis (salt and water diuresis) and lower urinary tract symptoms (LUTS) in postmenopausal women
- Conditions
- Nocturia, Menopause, LUTS, Diuresis
- Trial name
- HODI (NCT04891926)
- Testing
- ICIQ FLUTS Questionaires, Frequency Volume Chart, Renal Function Profile
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Menopause, Quality of Life
Effect of Structured Education on Menopause-Specific Quality of Life
This study aims to evaluate the impact of a structured education program delivered under midwife guidance on menopause-specific quality of life among women aged 45-55 undergoing natural menopause, and to assess the sustainability…
- Trial name
- NCT06979947
- Testing
- Structured Menopause Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Inonu University
Infertility
What is the Best Preparation for Embryo Transfer in Cryo Cycles: a Natural Cycle or Light Hormonal Stimulation?
The study investigates if, among women with a regular cycle (between 25 and 45 days), the endometrium is better prepared for the transfer of an embryo that was cryopreserved and if the subsequent embryo implantation rate is…
- Trial name
- NCT00492934
- Testing
- human menopausal gonadotrophins
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Perimenopause, Menopause
Impact of Cannabinoids on Menopause Symptoms
The purpose of the study is to examine the impact of the hemp-derived minor cannabinoids on symptoms of menopause/perimenopause.
- Trial name
- NCT06831916
- Testing
- Active Cannabinoid Product
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Washington State University
Menopause Hot Flashes
MT-8554 for Reduction of Vasomotor Symptoms in Postmenopausal Women
The purpose of this study is to assess the efficacy and safety of MT-8554 for treatment of vasomotor symptoms (VMS) associated with menopause.
- Trial name
- NCT03291067
- Testing
- MT-8554 1mg, MT-8554 5mg, MT-8554 10mg
- Where
- 63 sites in United States
- Volunteers
- 375 people
- Sponsor
- Tanabe Pharma America, Inc.
Dysmorphic Disorder (BDD), Congenital Labia Majora Hypotrophy
To Assess The Performance And Tolerance Of Janesse 20 In The Volume Restoration Of Labia Majora
The use of hyaluronic acid (HA)-based fillers administered by injection to obtain Labia Majora augmentation is performed by many surgeons and gynaecologists in Europe, US and other countries, but few studies have investigated the…
- Conditions
- Dysmorphic Disorder (BDD), Congenital Labia Majora Hypotrophy, Post-menopausal Labia Majora Hypotrophy
- Trial name
- NCT04936763
- Testing
- Janesse 20 (Cross-linked Hyaluronic Acid)
- Where
- 2 sites in Italy, Romania
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- I.R.A. Istituto Ricerche Applicate S.p.A.
Menopausal Syndrome
A Real-world Clinical Study on the Treatment of Menopausal Syndrome With Liuwei Dihuang Pills
To evaluate the clinical efficacy of the real-world Liuwei Dihuang pills for the treatment of female menopausal syndromes, and to provide a basis for effective, safe and rational clinical use of the drug.
- Trial name
- NCT06874738
- Testing
- Liuwei Dihuang pills
- Volunteers
- 1,000 people
- Sponsor
- China Academy of Chinese Medical Sciences
Breast Cancer
Effect of a Natural Health Product on Urinary Estrogen Metabolites
The purpose of this study is to determine if a supplemental formula can beneficially alter the ratio of urinary estrogen metabolites.
- Trial name
- NCT01089049
- Testing
- FemMED Breast Health Formula
- Where
- Canada
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Nutrasource Pharmaceutical and Nutraceutical Services, Inc.
Menopause, Type 2 Diabetes
Menopausal Hormone Therapy, GLP-1 Agonists, and Glucose and Energy Homeostasis in Postmenopausal Women With Overweight/Obesity and Impaired Glucose Homeostasis
The overall aim is to investigate the hypothesis that restoring E2 levels through MHT improves glucose and energy homeostasis and potentiates the beneficial effects of GLP-1RA in early postmenopausal women with pre- or existing…
- Trial name
- DECLARED-CT (NCT06715514)
- Testing
- GLP-1 Receptor Agonist, Menopausal Hormone Therapy
- Where
- Switzerland
- Volunteers
- 96 people
- Sponsor
- Lia Bally
Osteopenia, Osteoporosis
Calcium-Rich Food Versus Calcium Carbonate for Bone Health
This study will compare adherence, tolerability, safety, and treatment satisfaction between a calcium-rich food and a traditional calcium carbonate supplement in women ages 40 to 90 who are at increased risk for osteoporosis.
- Conditions
- Osteopenia, Osteoporosis, Bone Health in Perimenopausal Women, Menopause Related Conditions
- Trial name
- NCT07763509
- Testing
- 500 mg calcium from milk-derived minerals, Calcium Carbonate 500 MG
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Cornell University
Periodontitis, Menopause
Evaluation of Periodontal Response to Non Surgical Therapy in Pre and Post Menopausal Women With Periodontitis
The present study was evaluated periodontal status in pre and post-menopausal women with periodontitis following non-surgical therapy.
- Conditions
- Periodontitis, Menopause, Plaque, Inflammation
- Trial name
- EPRNPPMP (NCT02718014)
- Testing
- scaling and root planing (srp)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
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