Clinical trials: Menopausal
Post-menopausal Osteoporosis
Bisphosphonate Action on the Appendicular Skeleton: Evidence for Differential Effects
A study to determine if the three licensed bisphosphonates (alendronate, ibandronate and risedronate):a) affect the peripheral skeleton differently, as assessed by quantitative ultrasound of bone (QUS), peripheral quantitative…
- Trial name
- NCT00666627
- Testing
- Ibandronate, Risedronate, Alendronate
- Where
- United Kingdom
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Menopause, Non Alcholic Fatty Liver Disease
MHT and Liver Function in Postmenopausal Women
This prospective study aims to evaluate the effects of menopausal hormone therapy (MHT) on liver function, lipid profiles, and hepatic steatosis in postmenopausal women.
- Conditions
- Menopause, Non Alcholic Fatty Liver Disease, Hepatic Steatosis
- Trial name
- NCT07103603
- Testing
- Menopausal hormone therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ipek B. Ozcivit Erkan, MD
Disorder Associated With Menstruation and/or Menopause, Dyslipidemia
The Roles of SAH Gene Family in Athrogenic Dyslipidemia in Postmenopausal Women
Atherogenic dyslipidemia is characterized by high levels of apolipoprotein B (apoB)-containing lipoproteins, including very-low-density lipoprotein (VLDL) and its remnants and small, dense LDL (sdLDL) particles, and reduced…
- Trial name
- MOSAH-S2 (NCT00945217)
- Where
- Taiwan
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Menopause, Depression
Brain Imaging Study in Menopausal Women With and Without Major Depressive Disorder
The purpose this study is to measure cortical gama-aminobutyric acid levels (GABA) levels in menopausal women with major depressive disorder and healthy subjects using nuclear magnetic resonance spectroscopy (MRS).
- Trial name
- NCT00626340
- Testing
- MDD diagnosis and Estrogen treatment, MDD diagnosis and Fluoxetine treatment, MDD diagnosis with both Estrogen and Fluoxetine treatment
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Hot Flashes
A Clinical Trial to Demonstrate the Efficacy and Safety of Cenestin 0.3 mg for the Treatment of Hot Flashes
This is a randomized, double-blind study to compare the efficacy and safety of daily doses of Cenestin 0.3 mg tablets to placebo in reducing the frequency and severity of moderate to severe hot flashes in postmenopausal women.
- Trial name
- NCT00272935
- Testing
- Cenestin 0.3 mg Tablets
- Where
- 49 sites in United States
- Volunteers
- 400 people
- Sponsor
- Duramed Research
Infertile Women Undergoing Assisted Reproductive Technology (ART)
A Study to Compare the Safety and Efficacy of Cetrotide® 3 Milligram (mg) Versus Antagon™ in Women Undergoing Ovarian Stimulation
To demonstrate the comparative safety and efficacy of Cetrotide® 3 milligram (mg) and Antagon™ in the inhibition of a premature luteinizing hormone (LH) surge in women undergoing ovarian stimulation with recombinant human…
- Trial name
- NCT00298025
- Testing
- Cetrotide®, Antagon ™, Recombinant human follicle stimulating hormone (r-hFSH)
- Volunteers
- 185 people
- Sponsor
- EMD Serono
Overweight, Obesity
Effects of Red Beetroot Juice on High-Fat Meal-Induced Endothelial Dysfunction and Cardiometabolic Disturbances
Aside from aging, numerous factors increase the risk for developing cardiovascular disease (CVD) including diet and nutrition. High-fat meal consumption induces postprandial vascular endothelial dysfunction and other…
- Conditions
- Overweight, Obesity, Aging, Menopause
- Trial name
- NCT02949115
- Testing
- 70 mL red beetroot juice, 70 mL red beetroot juice without nitrate
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Menopausal Symptom
Effect of Reiki Application on Menopausal Symptoms
In this randomized controlled study, it was aimed to determine the effect of distant reiki on menopausal symptoms. Two different hypothesis teams have been established for the study.
- Trial name
- NCT05342610
- Testing
- Distant reiki
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mersin University
Osteoporosis, Osteoporotic Fracture of Vertebra
Development and Evaluation of an Exercise Intervention for Prevention of Vertebral Osteoporosis and Deformity in Postmenopausal Women
Osteoporotic fractures of the vertebrae (bones in the back) cause substantial pain and disability. Exercise could help to prevent these fractures by increasing bone strength and improving posture.
- Conditions
- Osteoporosis, Osteoporotic Fracture of Vertebra, Postural, Thoracic Kyphosis
- Trial name
- NCT04660825
- Testing
- A resistance band exercise programme, Control
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Osteoporosis
Open Label Extension
TRES will evaluate the effects of continued ALX1-11 treatment on the safety and efficacy variables assessed in the OLE study for a maximum treatment duration of 36 months in OLES and TRES combined.
- Trial name
- TRES (NCT00172120)
- Testing
- ALX1-11
- Where
- 12 sites in United States, Argentina
- Volunteers
- 91 people
- Sponsor
- Shire
Uterine Fibroids
Extension Study of Proellex in Women Who Have Previously Completed Study ZPU 003
ZPU-003 EXT is a 2-year extension study of ZPU-003 (NCT00882258) to determine the continued safety and efficacy of Proellex in women who have previously completed the double-blind portion of the study.
- Trial name
- NCT00958334
- Testing
- Proellex®
- Where
- 11 sites in United States
- Volunteers
- 65 people
- Sponsor
- Repros Therapeutics Inc.
Breast Cancer, DCIS
CyberKnife Stereotactic Accelerated Partial Breast Irradiation (SAPBI)
This study will prospectively evaluate the technical feasibility, acute toxicity, late effects and oncologic outcomes of CyberKnife Stereotactic Accelerated Partial Breast Irradiation (CK-SAPBI) in early stage breast cancer.
- Conditions
- Breast Cancer, DCIS, Invasive Ductal Carcinoma
- Trial name
- CK-SAPBI (NCT02365714)
- Testing
- CK Stereotactic Accelerated Partial Breast Irradiation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Georgetown University
Perimenopausal Disorder
Efficacy and Safety for Cimicifuga/Hypericum Product
Climacteric Complains bring to women many problems for living a normal life - hot flashes, irritation are 2 of many problems and the mixture of those 2 plant extract must bring a new horizon for this part of time.
- Trial name
- CH (NCT01481025)
- Testing
- Cimicifuga + Hiperico, Cimicifuga Herbarium, Aplause®
- Where
- Brazil
- Volunteers
- 210 people
- Sponsor
- Phytopharm Consulting Brazil
Post Menopausal Obese Women
Effect of Upper Limb Ergometer on the AIP in Post Menopausal Obese Women.
Participants had randomly divided into two equal groups. Group (A) which is the control group receive normal routine medication.
- Trial name
- NCT04676074
- Testing
- Electronic Upper limb( body) ergometer
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Late-Onset Asthma
Asthma Severity in Women: The Influence of Training and Menopause
Introduction: Late-onset asthma in women is characterized by poor disease control and reduced quality of life despite intensive treatment with inhaled steroid and beta2-agonist.
- Trial name
- ATOM (NCT03747211)
- Testing
- Aerobic exercise
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Therapeutic Touch, Menopausal Symptoms
The Effects of Reiki on Menopausal Symptoms and Depression Levels
Objective: This study was conducted to determine the effects of Reiki applied to women in the postmenopausal period on menopausal symptoms and depression levels.
- Trial name
- NCT05977426
- Testing
- Reiki
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Inonu University
Hypertension (HTN)
NR and Exercise for Blood Pressure
Hypertension continues to pose a significant global health challenge, with rates of optimal blood pressure control remaining low - particularly in China, where fewer than 5% of individuals with hypertension achieve…
- Trial name
- NCT07475208
- Testing
- Brisk walking, Nicotinamide Riboside 1000 mg
- Volunteers
- 112 people
- Sponsor
- ZHANG Jiaqi
Menopause
Study Comparing 3 New Formulations of Premarin® 0.625 mg/MPA 2.5 mg With a Reference Formulation
The purpose of this trial is to determine the equivalence of 3 new formulations of a Premarin®/medroxyprogesterone acetate (MPA) combination tablet to the currently marketed dosage form (Prempro® [TM]).
- Trial name
- NCT00630435
- Testing
- Premarin®/MPA formulation A, Premarin®/MPA formulation B, Premarin®/MPA formulation C
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Quality of Life
The Quality of Life in Late Menopause
The purpose of this study is to evaluate the quality of life of late postmenopausal Finnish women and the factors affecting it.
- Trial name
- QoL (NCT01848223)
- Where
- Finland
- Volunteers
- 64 people
- Sponsor
- Turku University Hospital
Menopause, Genitourinary Syndrome of Menopause
Examining Effects of Intrarosa in Women With Genitourinary Syndrome of Menopause/Vulvovaginal Atrophy
Tissues of the genitals of women are both androgen (testosterone) and estrogen dependent. The clitoris, vestibule, urethra, anterior vaginal wall, peri-urethral tissue, and pelvic floor all depend on androgens for normal…
- Conditions
- Menopause, Genitourinary Syndrome of Menopause, Vulvovaginal Atrophy, Menopause Syndrome
- Trial name
- NCT03782480
- Testing
- Intrarosa
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Center for Vulvovaginal Disorders
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