Clinical trials: Menopausal
Perimenopause, Perimenopause-Related Depression
Intra Ovarian Muse Cell Injection for Perimenopause Symptom Relief and Ovarian Function Restoration (MUSE-OVARY)
This observational study examines the safety and effects of injecting Muse cells (a type of naturally occurring stem like cells found in adult tissues such as fat or bone marrow) directly into the ovaries of women aged 28 to 70…
- Conditions
- Perimenopause, Perimenopause-Related Depression, Premature Ovarian Insufficiency, Premature Ovarian Failure (POF)
- Trial name
- MUSE-OVARY (NCT07511660)
- Where
- Mexico
- Volunteers
- 12 people
- Sponsor
- Healing Hope International
Post Menopausal Dryness in the Intimate Area of Women
Microbiological Impact of an Intimate Cream and Its Suitability to Contribute to the Feeling of Softness and Freshness in the Intimate Area of Women
Generate more information on the use of the Probiotic Intimate Crème regarding feeling of dryness and freshness in the intimate area, as well as to evaluate the Lactobacillus flora and presence of coliform bacteria in respect to…
- Trial name
- NCT02162160
- Testing
- probiotic creme
- Where
- Sweden
- Volunteers
- 18 people
- Sponsor
- Karolinska Institutet
Menopause, Visual Impairment and Blindness (Excl Colour Blindness)
Audio-Described Menopause Education Program in Visually Impaired Women
This randomized controlled trial was conducted to evaluate the effect of an audio-described menopause education program on menopause knowledge and menopausal symptoms in women with visual impairment.
- Conditions
- Menopause, Visual Impairment and Blindness (Excl Colour Blindness), Menopausal Symptoms, Women's Health Education
- Trial name
- NCT07771946
- Testing
- Audio-Described Menopause Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Ankara University
Breast Cancer, Menopause
Comparison of the Efficacy and Tolerability of Femal Versus Placebo
Femal, a food supplement based on pollen extracts introduced in Europe in 1999, is a non-estrogenic alternative to hormone replacement therapy in women with vasomotor symptoms.
- Trial name
- NCT05762042
- Testing
- dietary supplement
- Where
- 2 sites in Italy
- Volunteers
- 34 people
- Sponsor
- Azienda Ospedaliera Ordine Mauriziano di Torino
Major Depressive Disorder, Menopausal Staging and Vasomotor Symptoms (for Females)
Desvenlafaxine Succinate (DVS) for Major Depressive Disorder (MDD) in Midlife Men and Women
The main objective of this study is to characterize a range of brain activation symptoms associated with depression and response to treatment in midlife men and women with MDD, using MRI and functional MRI.
- Trial name
- DVS (NCT00888862)
- Testing
- Desvenlafaxine Succinate
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Menopause, Sleep
The Effect of Interactive Game Supported Sleep Hygiene Training on Sleep Quality, Menopausal Symptoms and Quality of Life in Menopausal Women
This study will present an innovative approach for sleep hygiene education in this age group by developing an interactive game-based education model for menopausal women.
- Trial name
- NCT06750562
- Testing
- interactive game
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Meryem Vural Şahin
Sexual Dysfunction, Menopause
Effectiveness of Pelvic Floor Exercises and Sexual Education in Women Over 60
Since the mid-19th century, "old age" has been increasingly recognized as a natural life stage, especially as the human lifespan extends.
- Conditions
- Sexual Dysfunction, Menopause, Pelvic Floor Disorders
- Trial name
- NCT06539897
- Testing
- Sexual education
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Sexual Dysfunction
Erbium Laser for Treatment of Vaginal Looseness and Sexual Dysfunction.
Patients with a primary complaint of vaginal looseness and sexual dysfunction, visiting a sexual dysfunction clinic at a tertiary medical center will undergo randomization to either a series of 3 laser treatments or 3 sham…
- Trial name
- NCT04228679
- Testing
- Erbium laser
- Where
- Israel
- Volunteers
- 106 people
- Sponsor
- Rambam Health Care Campus
Menopause Related Conditions
Study of Progesterone in Treatment of Vasomotor Symptoms
The primary objective of the clinical trial is to demonstrate superiority of BHR401 (oral micronized progesterone) versus placebo as a monotherapy for moderate to severe VMS in postmenopausal women.
- Trial name
- PROGEST (NCT03202186)
- Testing
- Progesterone oral capsule
- Where
- Germany
- Volunteers
- 55 people
- Sponsor
- BHR Pharma, LLC
Anorexia Nervosa
Impact of Denosumab in the Prevention of Bone Loss in Non-menopausal Women With Anorexia Nervosa
The drastic reduction of nutritional intake in anorexia nervosa(AN) alters many hormonal factors that regulate the activity of bone cells.
- Trial name
- DIBLAN (NCT02567279)
- Testing
- Denosumab subcutaneous injections
- Where
- France
- Volunteers
- 2 people
- Sponsor
- University Hospital, Montpellier
Chronic Kidney Disease, Secondary Hyperparathyroidism
Quality of Life in Greek Hemodialysis Patients Receiving Zemplar Intravenous
The purpose of this study is to assess health-related Quality of Life (QoL) changes in participants with chronic kidney disease (CKD) and secondary hyperparathyroidism (sHPT) undergoing hemodialysis and receiving paricalcitol…
- Trial name
- QUALITIZE (NCT01368042)
- Where
- 11 sites in Greece
- Volunteers
- 265 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Hypertension, Menopause, Premature
Autonomic Regulation of Blood Pressure in Premature and Early Menopausal Women
This is a cross-sectional study in which the investigators will determine the impact of premature/early menopause on MSNA, BP and baroreflex sensitivity in younger (≤49 yr old) and older (≥50 yr old) women.
- Conditions
- Hypertension, Menopause, Premature, Menopause, Blood Pressure
- Trial name
- NCT04439370
- Testing
- Microneurography to measure muscle sympathetic nerve activity (MSNA), Baroreflex sensitivity testing, Sympathoexcitatory Maneuvers
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Genitourinary Syndrome of Menopause (GSM)
A Clinical Study of Chinese Herbal Formula TJAOA103 in Treating Genitourinary Syndrome of Menopause
The goal of this clinical trial is to learn if Chinese herbal formula TJAOA103 works to treat genitourinary syndrome of menopause (GSM). It will also learn about the safety of TJAOA103.
- Trial name
- NCT07160127
- Testing
- TJAOA103
- Where
- China
- Volunteers
- 113 people
- Sponsor
- Tongji Hospital
Gastrointestinal Symptoms
Foot Reflexology and Acupressure on Gastrointestinal Symptoms
This research was planned to evaluate the effects of foot reflexology and acupressure applications on gastrointestinal symptoms in women going through menopause.
- Trial name
- Menopausal (NCT07528534)
- Testing
- Foot Reflexology, Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Osmaniye Korkut Ata University
Urinary Tract Infections, Vaginal Flora Imbalance
Vaginal Care System for Menopausal Women With Urinary Tract Infections
Menopausal women have an increased risk of recurrent urinary tract infections. This is likely due in part to hormonal changes occurring during menopause.
- Trial name
- NCT05573334
- Testing
- BioNourish
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Vaginal Biome Science
Hormone Therapy
Hormone Therapy and Angiotensin-Dependent Arterial and Renal Vasoconstriction in Humans
1. to investigate the association between route of administration of exogenous estrogen (transdermal vs. oral) and cardiorenal risk in cisgender (gender identity aligning with sex at birth) and transgender (gender identity not…
- Trial name
- NCT05442463
- Testing
- Captopril Tablets, Iohexol
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Autoimmune Diseases, Menopause
Inflammation, Autoimmunity and Healthy Ageing in Menopause Transition. An Observational, Cross-sectional Study
The goal of this observational study is to investigate the prevalence of autoimmune or immune-mediated conditions in women during the menopausal transition (aged 40-60 years).
- Trial name
- NCT07784400
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Menopause
Dose Finding Evaluation of Kudzu Root Extract in Women With Menopause Symptoms
The aim of the study is to investigate effects of daily intake of Nordic Kudzu for 28 days in 5 groups of 10 menopausal women with symptoms.
- Trial name
- KUDZU-01 (NCT04552106)
- Testing
- 3 caps x3/day, 3 caps x2/day, 2 caps x3/day
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Nordic Bioscience A/S
Post Menopause
High Intensity Resistance Training In Postmenopausal Women (HIRT)
Menopause is defined as a permanent cessation of menstrual cycle for 12 months due to intrinsic diminution of ovarian oocytes among women in older age.
- Trial name
- HIRT (NCT05052749)
- Testing
- High Intensity Resistance Training (HIRT), Low-moderate Resistance Exercise Training
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Menopause, Obesity and Overweight
Time-Restricted Eating in Menopause and HOrmone-sensitive Breast Cancers (TREMHO)
This study is aimed at women currently going through menopause, either as part of the natural process (physiological menopause), or following hormonal treatment for breast cancer.
- Trial name
- TREMHO (NCT06855784)
- Testing
- Time-Restricted Eating 16h/8h, Active Control
- Where
- Switzerland
- Volunteers
- 84 people
- Sponsor
- University Hospital, Geneva
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