Clinical trials: Menopausal
Menopause, Hot Flashes
Caria: Digital Intervention for Menopause Symptom
Menopause is the time of life when menstrual cycles cease. Women typically spend 30-40% of their lives in menopause. Individual experiences of menopause vary and although some women do not experience any significant symptoms…
- Trial name
- NCT04882982
- Testing
- Caria app, Menopause Education
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Illinois Chicago
Menopause
Midlife Empowerment and Longevity Through Optimizing Wellness
The goal of this observational longitudinal study is to understand how lifestyle behaviours, menopausal symptoms, and digital health data change over time in women experiencing perimenopause or menopause, and to evaluate whether…
- Trial name
- MELOW (NCT07713862)
- Testing
- MELOW
- Volunteers
- 200 people
- Sponsor
- National University Health System, Singapore
Arterial Stiffening, Aging
Sex Hormones and Atherosclerosis Prevention in Perimenopausal Women
The purpose of this study is to find out why women's arteries stiffen as they go through menopause, and how this is affected by estrogen loss.
- Conditions
- Arterial Stiffening, Aging, Menopause
- Trial name
- SHAPE (NCT00608062)
- Testing
- GnRHant - Ganirelix acetate, Transdermal estradiol patch
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Menopause
The Effect of Yoga Training on Menopausal Symptoms on Menopausal Women
Parallel to the increase in life expectancy by years, the population of women living in the post-menopausal period is also increasing.
- Trial name
- NCT04695808
- Testing
- yoga
- Where
- Cyprus
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Postmenopausal Osteoporosis
A Multicenter, Randomized Placebo Controlled Pilot MicroCT Study to Estimate the Effect of Treatment With Denosumab (AMG 162) and Alendronate Sodium in Postmenopausal Women With Low Bone Mineral Density
This study is structured to estimate the effect of denosumab, compared to placebo and alendronate, on several bone parameters.
- Trial name
- NCT00293813
- Testing
- Alendronate, Denosumab
- Volunteers
- 247 people
- Sponsor
- Amgen
Menopause
Hormone Estradiol Replacement Therapy Additional Herbals
The purpose of this study is to determine whether Hormone Replacement Therapy (HRT), safety studies are combined with herbal (garlic oil, rutin, and nattokinase) to reduce estrogen side effects.
- Trial name
- WH (NCT02618148)
- Testing
- ESTROGEN HERBALS 21, ESTROGEN HERBALS 28
- Where
- Vietnam
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Trieu, Nguyen Thi, M.D.
Postmenopausal Period, Menopausal Symptoms
Effects of Mindfulness-Based Self-Efficacy Development Program on Postmenopausal Women
The aim of this randomized controlled clinical trial is to evaluate the effects of a mindfulness-based self-efficacy development program on menopausal symptoms and quality of life in postmenopausal women.
- Conditions
- Postmenopausal Period, Menopausal Symptoms, Quality of Life, Stress Management
- Trial name
- MOPKA (NCT07034885)
- Testing
- Mindfulness-Based Self-Efficacy Development Program
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Nurcan Gökgöz
Breast Cancer
MammaPrint Value for Pre-menopausal Breast Cancer Patients
Nearly 200 cases are to be enrolled. The information of patient age, histologic grade, tumor size, ER and PR status, Ki-67 index, surgery mode should be provided.
- Trial name
- NCT05474391
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fudan University
Menopause
A Safety and Efficacy Study of the Combination Estradiol and Progesterone to Treat Vasomotor Symptoms
This study will be a prospective, randomized, double-blind, placebo-controlled, parallel group, multicenter trial of postmenopausal subjects with an intact uterus.
- Trial name
- REPLENISH (NCT01942668)
- Testing
- Estradiol, Progesterone
- Where
- 119 sites in United States
- Volunteers
- 1,845 people
- Sponsor
- TherapeuticsMD
Menopause Symptom Management, Quality of Life
Effect of Mandala Practice on Menopausal Symptoms and Quality of Life
Menopause is a natural cycle of life that mostly develops due to changes in the endocrine glands of the female body during middle age, and the menstrual cycle is permanently interrupted as a result of the ovaries losing their…
- Conditions
- Menopause Symptom Management, Quality of Life, Menopausal Symptoms
- Trial name
- NCT07149285
- Testing
- Mandala coloring
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Emine Karacan
Menopause Related Conditions
Emotional Freedom Technique (EFT) Applied to Postmenopausal Women on Sleep and Quality of Life
The study will be conducted as a randomized controlled experimental study to determine the effects of the Emotional Freedom Technique (EFT) applied to women in menopause on sleep quality and quality of life.
- Trial name
- NCT06578715
- Testing
- Emotional Freedom Technique
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Acute Ovarian Failure, Infertility
Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy
Background: Medical advances have improved survival rates for many cancers and other illnesses. This means that more people are coping with the long-term effects of these treatments. Some treatments can cause female infertility.
- Conditions
- Acute Ovarian Failure, Infertility, Early Menopause And Infertility In Females After Treatment For Childhood Cancer
- Trial name
- NCT05440617
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Urinary Tract Infections, Menopause
Characterization of Vaginal, Urinary and Fecal Microbiomes in Women With Recurrent Urinary Tract Infections
The objectives are to evaluate whether variations in vaginal and/or urinary and/or fecal microbiome predispose postmenopausal women to recurrent cystitis.
- Trial name
- NCT04305808
- Where
- Israel
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Endometriosis
A Study to Investigate the Safety, Tolerability, Food Effect, Pharmacokinetics and Pharmacodynamics of FOR-6219
This is a randomised, double-blind, placebo-controlled, Phase I/Ib study which will assess the safety, tolerability, food effect, pharmacokinetics and pharmacodynamics of FOR-6219, a hydroxysteroid (17B) dehydrogenase (HSD17B1)…
- Trial name
- NCT03709420
- Testing
- FOR-6219
- Where
- United Kingdom
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Forendo Pharma Ltd
Frozen Shoulder, Adhesive Capsulitis
Effect of Hormone Replacement Therapy on Physiotherapy Outcomes in Postmenopausal Women With Frozen Shoulder
The purpose of this study is to compare the effects of a physiotherapy program on pain levels, shoulder range of motion, functional status, pain catastrophizing, perceived change, sleep quality, and quality of life in…
- Conditions
- Frozen Shoulder, Adhesive Capsulitis, Adhesive Capsulitis of the Shoulder, Hormone Replacement Therapy, Post-Menopausal
- Trial name
- NCT07736027
- Testing
- Standardized Physiotherapy Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University - Cerrahpasa
Menopause Symptoms
Study to Evaluate the Effects of the Cooling Bolero in Women With Common Menopause Symptoms
The Cooling Bolero is a a vest filled with a new material (not ice or a gel) that provides controlled cooling by absorbing heat. The vest is manufactured by Nanohealth.
- Trial name
- NCT02795741
- Testing
- Cooling Bolero
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Englewood Hospital and Medical Center
Sleep Apnea, Obesity
Upper Airway of Women With Obstructive Sleep Apnea After Bariatric Surgery
Evaluation of upper airway with Magnetic Resonance and polysomnographic at the pre and post operative of 23 women having undergone bariatric surgery (with the Y-Roux technique) for treatment of obesity.
- Trial name
- NCT05669469
- Testing
- Bariatric surgery
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- Michel Burihan Cahali
Dry Eye
Herbal Medication to Treat Dry Eye in Peri/ Post-menopausal Women
Dry eye disease (DED) in less severe forms are very common, and should ideally be treated outside hospitals, eg., through primary care services and exploiting holistic therapies such as traditional medicine.
- Trial name
- NCT05319041
- Testing
- Wei's Qi Ju Gan Lu Formula
- Where
- Singapore
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Menopause
The Development, Validation and Application of a Novel Questionnaire Developed by ZOE Ltd Measuring Menopause Symptoms and Subjective Quality of Life
The MenoScale has been developed from the most common symptoms identified in over 70,000 women to reflect symptom prevalence and user-friendly terminology. It builds and improves on pre-existing scoring tools in four main ways.
- Trial name
- NCT06800560
- Testing
- MenoScale, Greene Climacteric Scale, RAND 36-Item Health Survey 1.0
- Where
- United Kingdom
- Volunteers
- 1,100 people
- Sponsor
- Zoe Global Limited
Hot Flashes
Black Cohosh Extract for the Management of Moderate to Severe Menopausal Symptoms in Thai Women
Cimicifuga racemosa (black cohosh) rhizome and root extract have been used to treat menopausal symptoms. To date, there are still scarce information about its efficacy in Thai women with menopausal symptoms.
- Trial name
- NCT01487694
- Testing
- cimicifuga racemosa
- Where
- Thailand
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mahidol University
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