Clinical trials: Menopausal Hot Flashes
Breast Cancer, Handheld Fan
Use of Handheld Fans in Management of Hot Flashes in Women With Breast Cancer Receiving Hormonetherapy
Hot flushes are a common symptom in women with breast cancer receiving hormone therapy. It can lead to conditions that reduce quality of life such as sleep quality deterioration, sexual problems and discomfort in daily life.
- Conditions
- Breast Cancer, Handheld Fan, Hot Flashes, Hormonetherapy
- Trial name
- Breast Cancer (NCT07054957)
- Testing
- Handheld fan, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Izmir Bakircay University
Menopause
Menopause and Meditation for Breast Cancer Survivors
One of the consequences of breast cancer treatment for younger women is the abrupt onset of menopause and its related symptoms. Menopausal symptoms disrupt usual activities, alter sleep patterns and decrease quality of life.
- Trial name
- NCT00156416
- Testing
- Mindfulness Meditation
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Pittsburgh
Menopause Hot Flashes
Fezolinetant and Vascular Health and Brain Health
The goal of this clinical trial is to learn whether a study drug called fezolinetant impacts cardiovascular and cognitive health in women who have moderate to severe menopausal hot flashes and night sweats.
- Trial name
- FAVES-B (NCT07606664)
- Testing
- Fezolinetant
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- Rebecca Thurston
Hot Flashes, Acupuncture Therapy
Effectiveness of Electro-Press Needle and Gamma-Oryzanol for Menopause-associated Hot Flashes
The investigators plan to conduct the randomized controlled trial to evaluate the effectiveness of electro-press needle (EPN), a novel acupuncture needle combining shallow and gentle insertion with transdermal electrical…
- Conditions
- Hot Flashes, Acupuncture Therapy, Perimenopausal Disorder, Postmenopausal Symptoms
- Trial name
- NCT05922800
- Testing
- Electro Press Needle, Gamma-Oryzanol
- Volunteers
- 64 people
- Sponsor
- Dongzhimen Hospital, Beijing
Amenorrhea, Hot Flashes
Hydrotherapy Against Menopausal Symptoms in Breast Cancer Survivors
Breast cancer survivors often suffer from climacteric symptoms caused by treatment or diagnosis of their disease. Hormone replacement therapy is contraindicated and other pharmacological options may also include the risk of…
- Trial name
- NCT00243607
- Testing
- hydrotherapy according to Kneipp rules
- Where
- Germany
- Volunteers
- 45 people
- Sponsor
- Heidelberg University
Postmenopausal Symptoms, Hot Flashes
Strength and Aerobic Training Against Hot Flushes in Postmenopausal Women
The goal of this randomised controlled trial is to investigate the effects of and compare two modes of physical exercise (strength training and high-intensity aerobic exercise) to unchanged physical activity on vasomotor symptoms…
- Trial name
- START (NCT06030388)
- Testing
- Strength training, High-intensity aerobic training
- Where
- 2 sites in Sweden
- Volunteers
- 90 people
- Sponsor
- Linkoeping University
Anxiety Disorder, Breast Cancer
Acupuncture in Reducing Muscle and Bone Symptoms in Women Receiving Letrozole, Exemestane, or Anastrozole for Stage 0, Stage I, Stage II, or Stage III Breast Cancer
RATIONALE: Acupuncture may help relieve muscle and bone pain caused by aromatase inhibitor therapy, such as letrozole, exemestane, and anastrozole.
- Conditions
- Anxiety Disorder, Breast Cancer, Depression, Fatigue
- Trial name
- NCT00641303
- Testing
- acupuncture therapy
- Where
- 2 sites in United States
- Volunteers
- 51 people
- Sponsor
- University of Maryland, Baltimore
Sleep Initiation and Maintenance Disorders, Depression
Estrogen for Treating Depression in Menopausal Women With Hot Flashes and Insomnia
This study will evaluate the effectiveness of estrogen replacement therapy in treating depression in menopausal women with hot flashes and insomnia.
- Trial name
- NCT00227942
- Testing
- Estrogen Replacement Therapy, Zolpidem
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Hadine Joffe, MD
Fatigue, Hot Flashes
Acupuncture in Treating Hot Flashes in Patients With Prostate Cancer
RATIONALE: Acupuncture may help relieve hot flashes in patients with prostate cancer. PURPOSE: This clinical trial is studying how well acupuncture works in treating hot flashes in patients with prostate cancer who are undergoing…
- Conditions
- Fatigue, Hot Flashes, Prostate Cancer
- Trial name
- NCT00244894
- Testing
- acupuncture therapy, fatigue assessment and management, hot flashes attenuation
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- OHSU Knight Cancer Institute
Postmenopausal Vasomotor Symptoms, Cardiovascular Disease
Comparison of Vascular Findings Between Symptomatic and Asymptomatic Postmenopausal Women Before and During Hormone Therapy (HRT)
Recent large randomized, placebo-controlled studies assessing the health effects of HT question the overall benefits of long term HT, especially with respect to cardiovascular disease.
- Trial name
- SYMPTOM (NCT00668603)
- Testing
- 17-b-estradiol, 17-b-estradiol + medroxyprogeterone acetate, 17-b-estradiol hemihydrate
- Where
- Finland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Menopause
Symptom Monitoring and Menopausal Symptoms
A recent systematic review suggested that symptom monitoring can result in reductions in menopausal symptoms and improvements in health-related behaviours.
- Trial name
- NCT05603234
- Testing
- Symptom Monitoring
- Where
- United Kingdom
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of South Wales
Menopausal Hot Flashes, Menopausal Women
The Effectiveness of a Proprietary Ashwagandha Extract on Menopausal Symptoms: A Three-Arm Randomized, Double-Blinded, Placebo Controlled Clinical Trial
The purpose of this study is to evaluate the efficacy of two proprietary ashwagandha extracts on symptoms of menopause and hormone levels, as compared to a placebo.
- Trial name
- NCT07210229
- Testing
- ashwagandha root, ashwagandha root and leaf
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Nutraceuticals Research Institute
Vasomotor Symptoms
Mindfulness-Based Stress Reduction for Hot Flashes
This is a study to determine if participation in a mindfulness-based stress reduction program is feasible for women experiencing five or more hot flashes/day, and whether it affects either the frequency and/or intensity of their…
- Trial name
- NCT01052454
- Testing
- Mindfulness-based stress reduction
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Menopausal Flushing
Neuropeptide Treatment for Hot Flushes During the Menopause
Placebo-controlled, double-blinded, cross-over clinical trial of a new investigational product
- Trial name
- NK3R (NCT02668185)
- Testing
- NK3R antagonist - AZD4901
- Where
- United Kingdom
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Hot Flashes, Menopause
MsFLASH-03: Comparative Efficacy of Low-Dose Estradiol and Venlafaxine XR for Treatment of Menopausal Symptoms
The primary objective of this study is to determine the efficacy of both low-dose oral (by mouth) 17-ß-estradiol and the non-hormonal drug venlafaxine XR compared to placebo in reducing hot flashes.
- Conditions
- Hot Flashes, Menopause, Vasomotor Disturbance
- Trial name
- NCT01418209
- Testing
- Low-dose 17-ß-estradiol with progesterone taper, Venlafaxine XR
- Where
- 4 sites in United States
- Volunteers
- 339 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Breast Cancer
Study Evaluating Hot Flashes in Hormone Sensitive Breast Cancer
The validation of the HFRDIS questionnaire in French will allow the use in common practice of this questionnaire in consultation in order to have a concrete and reproducible assessment of the impact of hot flashes on the daily…
- Trial name
- HOTSHOT (NCT04775043)
- Testing
- HFRDIS questionnaire completion
- Where
- France
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Institut Curie
Menopause, Hot Flashes
Evaluate the Effect of Omega-3 vs Soy Isoflavones in Postmenopausal Women With Moderate to Severe Vasomotor Symptoms
This study is aiming to evaluate changes in vasomotor symptoms in postmenopausal women treated for 4 months with Omega-3 vs Soy Isoflavones.
- Trial name
- OMEGASI (NCT02195609)
- Testing
- Omega-3, Soy Isoflavones
- Where
- Spain
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Instituto Palacios
Menopause, Hot Flashes
A Dose-ranging Study of the Efficacy of ESN364 in Postmenopausal Women Suffering Vasomotor Symptoms (Hot Flashes)
This study determined the effects of different doses and dosing regimens of ESN364 on the frequency and severity of hot flashes.
- Trial name
- NCT03192176
- Testing
- Fezolinetant
- Where
- 51 sites in United States
- Volunteers
- 356 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Breast Cancer, Hot Flashes
Menopausal Symptoms in Women With Breast Cancer or At High Risk of Breast Cancer Treated on Another Clinical Trial
RATIONALE: Gathering information about the frequency and intensity of hot flashes in patients with breast cancer and in patients who have a high risk of developing breast cancer may help doctors learn more about menopausal…
- Trial name
- NCT00666913
- Testing
- informational intervention
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- Case Comprehensive Cancer Center
Postmenopausal Women With Moderate Vasomotor Symptoms
Clinical Trial to Evaluate the Efficacy of FITOGYN Versus Placebo on the Vasomotor Symptomatology Associated With Menopause
The purpose of this study is to evaluate the efficacy of FITOGYN vs. placebo on the vasomotor symptomatology associated with menopause, to evaluate the symptoms of anxiety, the metabolic parameters in menopause and to evaluate…
- Trial name
- TRYSEM (NCT01116310)
- Testing
- Soy isoflavones (Glycine max L) and red clover extract (Trifolium pretense L)
- Where
- 20 sites in Spain
- Volunteers
- 166 people
- Sponsor
- Laboratorios Casen-Fleet S.L.U.