Clinical trials: Menopause, Premature
Infertility, Premature Ovarian Failure
Flexible GnRH Antagonist vs Flare up GnRH Agonist Protocol in Poor Responders
The purpose of this study is to compare ovulation induction using a flexible GnRH antagonist protocol and flare up GnRH agonist protocol in IVF patients with poor response to ovarian stimulation.
- Trial name
- NCT00417066
- Testing
- Ganirelix 0.25mg (Orgalutran, Organon, The Netherlands), Arvekap 0.1mg (Triptorelin, Ipsen, France)
- Where
- Greece
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Eugonia
Premature Ovarian Failure
Premature Ovarian Failure (Genetic and Physiopathologic Analysis)
Premature Ovarian Failure (POF), syndrome observed in young woman, present consequences on hormonal and leads at definitive infertility.
- Trial name
- GéNIOP (NCT00780897)
- Where
- France
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Ovarian Failure, Ovarian Insufficiency
Ovarian Tissue Allo-transplantation
Premature ovarian failure, also known as primary ovarian insufficiency (POI), or premature menopause, affects 1-2% of women under 40.
- Conditions
- Ovarian Failure, Ovarian Insufficiency, Menopause Ovarian Failure, Menopause, Premature
- Trial name
- NCT06673004
- Testing
- Ovarian tissue allo-transplantation
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Poor Ovarian Response
A RCT Study on Autologous Cell Injection Into the Ovaries of Patients With POR
Poor ovarian response (POR) is a pathological state where the ovaries do not respond well to the stimulation of gonadotropins. It is mainly characterized by a small number of developing follicles, a high cancellation rate of the…
- Trial name
- NCT07282288
- Testing
- PRP injection, SVF injection
- Volunteers
- 198 people
- Sponsor
- Peking University Third Hospital
Premature Ovarian Insufficiency
Treatment of Premature Ovarian Insufficiency Using Bone Marrow Cells
investigator is doing single armed clinical interventional study to treat premature ovarian insufficiency with autologous bone marrow derived mononuclear cells to be given systematically and locally to the ovaries under…
- Trial name
- alfarah (NCT06302543)
- Testing
- autologous bone marrow cells injection
- Where
- Iraq
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- abdulmajeed hammadi
Infertility
Ovarian Stem Cells From Women With Ovarian Insufficiency
Background: Primary ovarian insufficiency (POI) is a condition that affects ovary function. It means that the ovaries are not able to function at a level appropriate for a woman's age.
- Trial name
- NCT01702935
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Primary Ovarian Insufficiency, Menopause, Premature
Oral Contraceptives as Infertility Treatments for Premature Ovarian Failure
Premature ovarian insufficiency (POI) is a life-changing condition that affects women in their reproductive age. There is a lack of reports which focus on how to improve the reproductive outcome of these women who wish to…
- Trial name
- NCT02757469
- Testing
- Drospirenone and ethinyl estradiol combination (Yasmin)
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Navy General Hospital, Beijing
Menopause
Bioidentical 'Natural' Hormone Evaluation in Early Menopause
Prospective double blind pilot study comparing bioidentical 'natural' hormones to low-dose PremPro. Forty participants will be enrolled.
- Trial name
- NCT00302731
- Testing
- Estradiol , estriol , progesterone, estradiol, progesterone, estriol, progesterone
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Jeanne Drisko, MD, CNS, FACN
Breast Cancer
Goserelin Acetate Study for Ovarian Function in Patients With Primary Breast Cancer
Primary Objective: To determine the effectiveness of goserelin acetate (Zoladex) in preserving ovarian function in premenopausal women undergoing neoadjuvant and/or adjuvant chemotherapy for primary invasive breast cancer by…
- Trial name
- NCT00429403
- Testing
- Goserelin
- Where
- 2 sites in United States, Japan
- Volunteers
- 1 people
- Sponsor
- M.D. Anderson Cancer Center
POI
Safety and Efficacy of YB-1113 in Treatment of POI
This phase 1 study is to evaluate the safety and tolerability of YB-1113 administered via intravenous (IV) infusion in the treatment of premature ovarian insufficiency (POI).
- Trial name
- NCT05494723
- Testing
- YB-1113
- Volunteers
- 6 people
- Sponsor
- Bright Cell, Inc.
Fertility Preservation, Alkylating Agents
Efficiency of Gonadotropin-releasing Hormone (GnRH) Agonist in Preventing Chemotherapy Induced Ovarian Failure
Chemotherapy drugs like alkylating agents are frequently used in various combined regimens to treat neoplastic and benign diseases.
- Conditions
- Fertility Preservation, Alkylating Agents, Lymphoma
- Trial name
- Erasme-POF (NCT01160315)
- Testing
- Triptorelin, Norethisterone acetate
- Where
- 15 sites in Belgium, France and 1 more
- Volunteers
- 118 people
- Sponsor
- Erasme University Hospital