Clinical trials: Menopause
Menopause
Improving Functioning Among Aging Women Veterans
Women are the fastest-growing group of U.S. Veterans. Over half of those using VA care are 45 or older, with more age-related health concerns than civilian women.
- Trial name
- NCT06580470
- Testing
- Tailored Cognitive Behavioral Therapy for Menopause
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- VA Office of Research and Development
Cardiovascular Diseases, Coronary Disease
Myocardial Infarction and Past Oral Contraceptive Use
To evaluate whether the long-term use of oral contraceptives, after discontinuation, was associated with an increased incidence of first nonfatal myocardial infarction among women above the age of 50.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Myocardial Infarction, Heart Diseases
- Trial name
- NCT00005173
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Menopause
Hormone Replacement Therapy and Insulin Action: A Double-Blind, Parallel, Placebo-Controlled Hormone Intervention Study in Postmenopausal Women
Considerable controversy exists regarding the effect of estrogen and progesterone on insulin sensitivity in postmenopausal women.
- Trial name
- NCT00005769
- Testing
- Hormone Replacement Therapy
- Where
- United States
- Sponsor
- National Center for Research Resources (NCRR)
Infertility
A Study on Efficacy and Safety of Menopur® Multidose in Korean Female Patients With Infertility
The purpose of this study is to investigate the ongoing pregnancy rates at 10-11 weeks after embryo transfer in patients treated with Menopur® Multidose
- Trial name
- NCT02835469
- Testing
- Menotrophin
- Where
- South Korea
- Volunteers
- 412 people
- Sponsor
- Ferring Pharmaceuticals
Breast Cancer
Retrospective Observational Trial on Reasons for Withdraw of Adjuvant Tamoxifen in Breast Cancer Patients
Retrospective observational trial on reasons for withdraw of Adjuvant Tamoxifen in Breast Cancer patients
- Trial name
- SOSTA (NCT00727883)
- Volunteers
- 190 people
- Sponsor
- AstraZeneca
Genitourinary Syndrome of Menopause
Clinical and Cyto-histological Evaluation of Fractional CO2 Laser Treatment on Genito-Urinary Syndromes of Menopause Related to Vaginal Atrophy
Estrogen deficiency can occur naturally during menopause or as a secondary effect of various treatments for breast or pelvic cancer and can lead to very disabling vulvovaginal symptoms, since it is associated with an anatomical…
- Trial name
- ATROVENANS (NCT05151380)
- Testing
- CO2 laser MonaLisa Touch ®
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Hopital Nord Franche-Comte
Postmenopausal Symptoms
Photobiomodulation in Post Menopause Genitourinary Syndrome
The goal of this project is to evaluate the clinical response of patients with symptoms of genitourinary menopause syndrome after the application of photobiomodulation in the vagina and its introit.
- Trial name
- NCT05557799
- Testing
- Photobiomodulation
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Backache, Low
Core Muscle Stability on Low Back Pain and Quality of Life in Post- Menopausal Women
Low back pain, postural dysfunction, loss of balance control and stability are musculoskeletal changes that occur over life span due to aging process and are inevitable.
- Trial name
- NCT03902132
- Testing
- Core Stability exercises group, Traditional low back physical therapy group
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Mild Gastrointestinal Symptoms in Healthy Adults, Low-grade Chronic Inflammation
Fungal Fiber for Gut Health
This study compares effects of plant based fiber vs fungi based fiber on clinical outcomes related to gut function (immunity, emotions, stress) and explores the role of gut microbiome structure and function on individual…
- Conditions
- Mild Gastrointestinal Symptoms in Healthy Adults, Low-grade Chronic Inflammation, Stress, Gut Health
- Trial name
- FUN4GUT (NCT06404749)
- Testing
- fungal fiber, inulin
- Where
- Argentina
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Future Biome SA
Menopausal and Female Climacteric States
Suan Tsao Jen Tang for Treating Menopause With Sleep Problem: a Clinical Observation
A prospective follow-up study was carried out in the Yang Ming branch of the Taipei City Hospital.Climacteric women with sleep difficulty received SZRT at a rate of 4.0 g, thrice daily for four weeks.
- Trial name
- NCT01267539
- Where
- Taiwan
- Volunteers
- 67 people
- Sponsor
- Taipei City Hospital
Urinary Incontinence, Menopause
Effects of Tanzberger Versus Pelvic Floor Muscle Exercises on Urinary Incontinence
Randomized clinical trial (RCT) will be conducted to compare the effects of Tanzberger exercises and pelvic floor muscle training on urinary incontinence and quality of life in post_menopausal females suffering from urine…
- Trial name
- NCT05916820
- Testing
- Tanzberger Exercises, Pelvic floor muscle training
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Healthy, Postmenopause
Fat Distribution in Healthy Early Postmenopausal Women
The aim of this study is to explore the effects of hormone replacement therapy with EV/DNG on abdominal fat distribution measured by magnetic resonance imaging.
- Trial name
- NCT00335218
- Testing
- Climodien / Lafamme (BAY86-5027)
- Where
- 3 sites in Austria
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Bayer
Menopause, Genitourinary Syndrome of Menopause
Examining Effects of Intrarosa in Women With Genitourinary Syndrome of Menopause/Vulvovaginal Atrophy
Tissues of the genitals of women are both androgen (testosterone) and estrogen dependent. The clitoris, vestibule, urethra, anterior vaginal wall, peri-urethral tissue, and pelvic floor all depend on androgens for normal…
- Conditions
- Menopause, Genitourinary Syndrome of Menopause, Vulvovaginal Atrophy, Menopause Syndrome
- Trial name
- NCT03782480
- Testing
- Intrarosa
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Center for Vulvovaginal Disorders
Alcohol Drinking, Weight Loss
The Effects of Alcohol Consumption on Central Adiposity
The objective of the proposed study is to enroll women with obesity that will undergo a controlled, energy restricted feeding intervention to test the effects of chronic ethanol consumption on adipose distribution and circulating…
- Conditions
- Alcohol Drinking, Weight Loss, Adiposity, Obesity
- Trial name
- CONSUME (NCT03521817)
- Testing
- Alcohol, No Alcohol
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Fall Injury, Incontinence
The Effect of Yoga on Decreasing Risk of Fall-Related Injury in Peri and Post-Menopausal
The primary objective of this study is to evaluate the effect of yoga on both fall risk factors AND capacity to successfully control landing and descent during a simulated fall among peri-and post- menopausal women.
- Conditions
- Fall Injury, Incontinence, Balance; Distorted
- Trial name
- NCT05106010
- Testing
- Balance Flow Yoga
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Postmenopausal Osteoporosis
A Study of Quarterly Intravenous Bonviva (Ibandronate) in Women With Post-Menopausal Osteoporosis.
This single arm study will assess the efficacy and safety of quarterly intravenous Bonviva in women with post-menopausal osteoporosis. All patients will receive Bonviva 3mg i.v. every 3 months.
- Trial name
- NCT00493532
- Testing
- ibandronate [Bonviva/Boniva]
- Where
- 14 sites in Taiwan
- Sponsor
- Hoffmann-La Roche
Menopausal Syndrome, Hot Flashes
Sulpiride Versus Placebo for Reducting Hot Flushes During Climacteric
Introduction: Estrogen hormonal therapy associated or not with progestagen is the standard therapy for the treatment of hot flushes.
- Trial name
- NCT02749747
- Testing
- Sulpiride use
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
HIV Prevention
Influence of Reproductive Cycle and Menopause on HIV-1 Infection and TFV Gel Activity
Purpose of the study is to assess tenofovir (TFV) PK and PD endpoints, cervicovaginal safety parameters, susceptibility to HIV-1 infection, and objective measures of vaginal applicator use in premenopausal and postmenopausal…
- Trial name
- NCT01810315
- Testing
- TFV 1% gel, Estradiol vaginal cream
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CONRAD
Menopausal Women
Effects of Cranial Massage in Menopausal Women
INTRODUCTION Menopause is one more stage in a woman's life. The hormonal change is associated with a series of symptoms that usually manifest around 50 years. Not all women manifest all the symptoms or with the same intensity.
- Trial name
- CM-MWin (NCT03565952)
- Testing
- Cranial massage, Control group
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Hot Flashes
A Study to Assess the Safety and Tolerability of Fezolinetant in Women Seeking Treatment for Relief of Vasomotor Symptoms (VMS) Associated With Menopause
This study is for women in menopause with hot flashes. Menopause, a normal part of aging, is the time of a woman's last period. Hot flashes can interrupt a woman's daily life.
- Trial name
- Moonlight 3 (NCT04451226)
- Testing
- Fezolinetant
- Where
- 29 sites in China
- Volunteers
- 150 people
- Sponsor
- Astellas Pharma China, Inc.
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