Clinical trials: Menopause
Climacteric Symptoms, Hot Flushes and/or Sweats
Development of Active Safety Surveillance System for Traditional Chinese Medicine
Context:Clinical trials demonstrating increased risk of cardiovascular disease and breast cancer among women randomized to hormone replacement therapy have attracted people's focus on the alternative therapy for menopausal…
- Trial name
- NCT00275964
- Testing
- TMN-1
- Sponsor
- National Taiwan University Hospital
Menopause
The Efficacy of ACupuncture On Menopausal Symptoms (ACOM)
As a natural part of the menopause the ovaries production of sex hormones declines. This can lead to different menopausal related symptoms.
- Trial name
- ACOM (NCT02746497)
- Testing
- Acupuncture
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Advanced Breast Cancer
Open-label, Phase II Study of Stomatitis Prevention With a Steroid-based Mouthwash in Post-menopausal Women With Estrogen-receptor-positive (ER+), Human Epidermal Growth Factor Receptor 2 (HER2)- Metastatic or Locally Advanced Breast Cancer
Open-label, Phase II study of Stomatitis prevention with a steroid-based mouthwash in Post-menopausal women with ER+, HER2- Metastatic or Locally Advanced Breast Cancer
- Trial name
- NCT02069093
- Testing
- Dexamethasone based mouthwash, Everolimus, Exemestane
- Where
- 23 sites in United States
- Volunteers
- 92 people
- Sponsor
- Novartis Pharmaceuticals
Low Bone Density, Osteopenia
A Taiwan Isoflavone Multicenter Study (TIMS)
Consumption of soy-based foods is associated with a number of health benefits, including lower risk of cardiovascular disease, breast and prostate cancer, attenuated menopausal symptoms and prevention of bone loss with age.
- Trial name
- NCT00262184
- Testing
- Soy Isoflavone
- Where
- 3 sites in Taiwan
- Volunteers
- 420 people
- Sponsor
- National Health Research Institutes, Taiwan
Menopause, Sleep Quality
Effect of Menopausal Hormone Therapy on Sleep
The Effect of Menopausal Hormone Therapy on Sleep (menoSLEEP) study is investigating the effects of menopausal hormone therapy (MHT) on sleep problems in peri- and postmenopausal women with an indication for MHT.
- Conditions
- Menopause, Sleep Quality, Psychological Wellbeing
- Trial name
- menoSLEEP (NCT07674316)
- Testing
- HRT
- Where
- Switzerland
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Infertility
Randomized Controlled Trial Comparing Embryonic Quality in rFSH Versus hMG in IVF Protocol With GnRH Antagonist
rFSH and HMG are both used to controlled ovarian stimulation for patients submitted to IVF. However, there is a debate in the literature which one is better to induce ovulation in patients receiving GnRH antagonist to block…
- Trial name
- NCT02412904
- Testing
- rFSH, HMG
- Where
- Brazil
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Immune System Disorder (Healthy Volunteer)
A Study to Determine the Effect of 500 mg Oral Dose of KD025 in Healthy Male and Post-menopausal Female Subjects
The purpose of this study is to determine the safety, tolerability, and pharmacokinetics of 500 mg oral BID dose of KD025 in healthy male and post-menopausal female participants.
- Trial name
- NCT05918614
- Testing
- Belumosudil mesylate
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Kadmon, a Sanofi Company
Menopause Syndrome, Menopause Surgical
Paroxetine Versus Placebo for Vasomotor Symptom Management in Surgical Menopause
evaluate the efficacy of paroxetine in the management of vasomotor symptoms in patients with surgical menopause, in order to seek an alternative therapy to hormone therapy, which is associated with proinflammatory and…
- Conditions
- Menopause Syndrome, Menopause Surgical, Hot Flashes
- Trial name
- MENOXTINA (NCT06763484)
- Testing
- Paroxetine
- Where
- Honduras
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Honduras
Multimorbidity, Multiple Chronic Conditions
Effect of Aerobic Training on the Health Parameters of Postmenopausal Women With Multimorbidity
People affected by multiple chronic diseases have a greater chance of hospitalization, longer hospital stays, worse general health, worse physical and mental function and lower functional capacity, with an average risk of 50% of…
- Conditions
- Multimorbidity, Multiple Chronic Conditions, Hypertension, Dyslipidemias
- Trial name
- NCT05075902
- Testing
- Aerobic training
- Where
- Brazil
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Menopause
Hormone Replacement Therapy and Insulin Action: A Double-Blind, Parallel, Placebo-Controlled Hormone Intervention Study in Postmenopausal Women
Considerable controversy exists regarding the effect of estrogen and progesterone on insulin sensitivity in postmenopausal women.
- Trial name
- NCT00005769
- Testing
- Hormone Replacement Therapy
- Where
- United States
- Sponsor
- National Center for Research Resources (NCRR)
Breast Cancer
Effect of PPARγ2 Polymorphism and NSAIDs on Acute Alcohol-induced Changes in Serum Estrogens Among Post-menopausal Women
Postmenopausal women, stratified by a peroxisome proliferator-activated receptor gamma-2 (PPARG) polymorphism, were given the following treatments in a random order with a 5w wash-out period: a 400mg ibuprofen tablet or a placebo…
- Trial name
- EPPNASE (NCT02463383)
- Testing
- Ibuprofen Tab 400 MG
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Professor Lars Ove Dragsted
Menopause
Midlife Empowerment and Longevity Through Optimizing Wellness
The goal of this observational longitudinal study is to understand how lifestyle behaviours, menopausal symptoms, and digital health data change over time in women experiencing perimenopause or menopause, and to evaluate whether…
- Trial name
- MELOW (NCT07713862)
- Testing
- MELOW
- Volunteers
- 200 people
- Sponsor
- National University Health System, Singapore
Vulvovaginal Atrophy
Performance and Safety of Hyalo Gyn Gel on the Treatment of Vaginal Atrophy in Postmenopausal Women
This clinical investigation evaluates the performance and safety of Hyalo Gyn, a hyaluronic acid derivative based vaginal gel for the treatment of symptoms of vulvo-vaginal atrophy in post-menopausal women.
- Trial name
- NCT04355403
- Testing
- Hyalo Gyn gel in prefilled applicators
- Where
- 2 sites in Slovakia
- Volunteers
- 80 people
- Sponsor
- Fidia Farmaceutici s.p.a.
Post Menopausal Osteoporosis
MOBILE Study - A Study of Bonviva (Ibandronate) Regimens in Women With Post-Menopausal Osteoporosis
This study will compare the efficacy and safety of different treatment regimens of oral Bonviva tablets in women with post-menopausal osteoporosis. Patients will also receive daily supplementation with vitamin D and calcium.
- Trial name
- NCT00048061
- Testing
- Ibandronate [Bonviva/Boniva], Calcium, Vitamin D
- Where
- 68 sites in United States, Australia and 17 more
- Volunteers
- 1,609 people
- Sponsor
- Hoffmann-La Roche
Sleep Initiation and Maintenance Disorders, Depression
Estrogen for Treating Depression in Menopausal Women With Hot Flashes and Insomnia
This study will evaluate the effectiveness of estrogen replacement therapy in treating depression in menopausal women with hot flashes and insomnia.
- Trial name
- NCT00227942
- Testing
- Estrogen Replacement Therapy, Zolpidem
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Hadine Joffe, MD
Atherosclerosis, Cardiovascular Diseases
Prevalence & Progression of Subclinical Atherosclerosis
To evaluate subclinical atherosclerotic disease in menopausal women.
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Coronary Arteriosclerosis, Carotid Artery Diseases
- Trial name
- NCT00006503
- Sponsor
- Rush University Medical Center
Cardiovascular Disease, Diabetes
The FLAVO Trial: Dietary Flavonoids and Cardiovascular Disease Risk Reduction in Postmenopausal Women With Type 2 Diabetes
The purpose of this placebo controlled trial is to determine whether a year long intervention with flavonoids (found in cocoa and soy) is more effective in reducing the risk of cardiovascular disease in postmenopausal women with…
- Trial name
- FLAVO (NCT00677599)
- Testing
- Flavonoid enrichment (cocoa / soy compounds)
- Where
- United Kingdom
- Volunteers
- 152 people
- Sponsor
- University of East Anglia
Obesity
Acupuncture for Obesity on Serum Metabolic Parameters
This research is planned to build a basis about the effect of acupuncture on serum metabolic parameters in pre-menopausal obese women with economic evaluation.
- Trial name
- NCT02066090
- Testing
- Real acupuncture
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Kyung Hee University Hospital at Gangdong
Females, Males
The Effects of Vitamin C on Acute-Exercise in Postmenopausal Females
This study is looking at whether vitamin C can help improve oxidative stress and blood vessel health in females after menopause.
- Conditions
- Females, Males, Menopause, Sedentary
- Trial name
- PM-VitC (NCT07109115)
- Testing
- Vitamin C (Ascorbic Acid)
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Menopause, Menopause Related Conditions
Pragmatic Weight Loss Intervention During Menopause
The investigators are using a community-based participatory research (CBPR) model to develop a lifestyle intervention targeting weight loss that is specifically tailored to women in perimenopause.
- Trial name
- WISE (NCT04487782)
- Testing
- Focus Groups
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Kara Marlatt
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.