Clinical trials: Menopause
Cardiometabolic Risk
Milk Polar Lipids Consumption, Lipid Metabolism, and Inflammation in Menopausal Women
Polar lipids have a specific chemical structure: they are an essential component of human cell membranes, play a major role in the nervous system and also influence the metabolic pathways including the cholesterol metabolism.
- Trial name
- VALOBAB-C (NCT02099032)
- Testing
- 3g milk polar lipid fortified cheese consumption, 5g milk polar lipid fortified cheese consumption, Unfortified cheese product consumption
- Where
- 2 sites in France
- Volunteers
- 59 people
- Sponsor
- Hospices Civils de Lyon
Menopause, Menopausal Symptoms
The Effect of Progressive Relaxation Exercises and Planned Education on Menopausal Symptoms, Perceived Stress, and Anxiety in Menopausal Women
The Effect of Progressive Relaxation Exercises and Planned Education on Menopausal Symptoms, Perceived Stress, and Anxiety in Menopausal Women
- Conditions
- Menopause, Menopausal Symptoms, Perceived Stress, Anxiety
- Trial name
- NCT07412093
- Testing
- Progressive relaxation, Planned education
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Breast Cancer
Triptorelin in Preventing Early Menopause in Premenopausal Women Who Are Receiving Chemotherapy for Stage I, Stage II, or Stage III Breast Cancer That Has Been Removed By Surgery
RATIONALE: Chemotherapy may cause early menopause in premenopausal women. Triptorelin may prevent this from happening. PURPOSE: This randomized phase III trial is studying triptorelin to see how well it works in preventing early…
- Trial name
- NCT00311636
- Testing
- cyclophosphamide, docetaxel, doxorubicin hydrochloride
- Where
- 18 sites in Italy
- Volunteers
- 280 people
- Sponsor
- Gruppo Italiano Mammella (GIM)
Post Menopausal Women With Early Breast Cancer
Sequencing Of Endocrine Therapy In Post-Menopausal Women With Early Breast Cancer (FAST)
Quality of life under therapy with Aromasin® (exemestane) according to IBCSG (International Breast Cancer Study Group) questionnaire. Change of the endometrium after switching from tamoxifen to Aromasin® (exemestane).
- Trial name
- FAST (NCT01050634)
- Testing
- Aromasin (exemestane)
- Volunteers
- 980 people
- Sponsor
- Pfizer
Vulvovaginal Atrophy
Efficacy and Safety of HYDEAL-D Vaginal Pessaries Application on the Treatment of Vaginal Atrophy in Post-menopause Women
This study evaluates the efficacy and safety of hyaluronic acid derivative based vaginal pessaries for the treatment of symptoms of vulvo-vaginal atrophy in post-menopausal women.
- Trial name
- NCT03557398
- Testing
- Hydeal-D vaginal pessaries
- Where
- 2 sites in Slovakia
- Volunteers
- 40 people
- Sponsor
- Fidia Farmaceutici s.p.a.
Vasomotor Symptoms, Hot Flushes
Dehydroepiandrosterone (DHEA) + Acolbifene Against Vasomotor Symptoms (Hot Flushes) in Postmenopausal Women
The purpose of this Phase III trial is to evaluate the efficacy of oral administration of dehydroepiandrosterone (DHEA) combined with acolbifene (a selective estrogen receptor modulator (SERM)) on vasomotor symptoms (hot flushes)…
- Trial name
- NCT01452373
- Testing
- DHEA and Acolbifene
- Where
- 15 sites in Canada
- Volunteers
- 238 people
- Sponsor
- EndoCeutics Inc.
Sleep Initiation and Maintenance Disorders, Menopause
Chinese Herbal Sachet Therapy for Sleep Quality in Menopausal Women
Many women sleep poorly during the menopausal transition. Some prefer not to take hormone therapy or sleeping tablets, and ask their nurses about other options.
- Trial name
- NCT07757724
- Testing
- Traditional Chinese medicine aromatic sachet
- Where
- Macau
- Volunteers
- 122 people
- Sponsor
- Macao Polytechnic University
Hot Flashes
A Mobile App for Hot Flashes and Sleep Disturbances
The purpose of the study is to compare the possible efficacy and acceptability of two mobile health applications for the reduction of hot flashes and related symptoms.This study is completely remote, and participants will be be…
- Trial name
- NCT06718803
- Testing
- Hypnosis, Structured Attention
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Baylor University
Breast Cancer
A Trial Using ARV-471 or Anastrozole in Post-Menopausal Women With Breast Cancer Prior to Surgery
This trial is a Phase 2 neoadjuvant study evaluating ARV-471 or anastrozole in post-menopausal women with estrogen receptor positive/ human epidermal growth factor receptor 2 (ER+/HER2)- localized breast cancer.
- Trial name
- NCT05549505
- Testing
- ARV-471, Anastrozole, Surgical resection of breast tumor
- Where
- 49 sites in United States, Georgia and 2 more
- Volunteers
- 152 people
- Sponsor
- Arvinas Inc.
Post-menopausal Period
Pharmacokinetics, Pharmacodinamic and Safety of Testosterone Gel 1%
This is a Phase I, open-label, parallel trial to evaluate Pharmacokinetics, Pharmacodynamics and Safety of Testosterone gel 1% for topic usage in post-menopausal women, for 28 days
- Trial name
- NCT02667561
- Testing
- Testosterone gel 1% 2.2 mg, Testosterone gel 1% 4.4 mg, Testosterone gel 1% 8.8 mg
- Volunteers
- healthy volunteers welcome
- Sponsor
- Biolab Sanus Farmaceutica
Stroke, Family Caregivers
Telephone Assessment and Skill-Building Intervention for Stroke Caregivers
The purpose of this study is to test the efficacy of the revised Telephone Assessment and Skill-Building Kit (TASK II) compared with an Information, Support, and Referral (ISR) intervention in family caregivers of stroke…
- Trial name
- TASKII (NCT01275495)
- Testing
- Telephone Assessment and Skill-Building Kit (TASK II), Information, Support, and Referral (ISR)
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Indiana University
Menopause
Eating Chocolate at the Right Time Benefits the Circadiam Sytem and Metabolic Efficiency.
The purpose of this investigation is to test the hypothesis that in humans, eating a relatively big amount of chocolate at the wrong time (bedtime) may disrupt our circadian system (change the circadian phase), while taking this…
- Trial name
- ONTIME-CHOC (NCT03949803)
- Testing
- Chocolate 100gr
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Insomniac Postmenopausal Women
Effect of Estrogen Therapy on Objective Sleep Quality in Postmenopausal Women
1. Sex hormone including estrogen have synergistic effect to serotonin activity and decrease activity of monoamine oxidase activity so the norepinephrine is not be metabolized, these substance are important to regulate hemostasis…
- Trial name
- NCT01501422
- Testing
- Estrogen patch
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Salpingectomy, Tubal Ligation
Stop Ovarian Cancer Young; Effect of the Opportunistic Salpingectomy on Age of Menopause
The aim of this study is to evaluate the long-term safety of on the onset of menopause.
- Conditions
- Salpingectomy, Tubal Ligation, Menopause
- Trial name
- STOPOVCAyoung (NCT04757922)
- Testing
- Opportunistic salpingectomy / bilateral salpingectomy
- Where
- Netherlands
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Menopause
Open-labelled Study to Evaluate the Effect of SE5-OH Tablets on Healthy Women With Menopausal Symptoms
Multicentre, exploratory, prospective, open-labelled study to evaluate the efficacy of SE5-OH tablets on menopausal symptoms in healthy women experiencing menopausal symptoms after 12 weeks of administration.
- Trial name
- NCT06398236
- Testing
- SE5-OH tablets
- Where
- Spain
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Nutrition & Sante Iberia
Postmenopausal Osteoporosis
A Study of Ibandronate (Boniva) to Evaluate Satisfaction in Women With Post-Menopausal Osteoporosis or Osteopenia
This study will investigate participant satisfaction (including compliance, preference, tolerability) with once-monthly Bonviva in women with post-menopausal osteoporosis or osteopenia transitioned from once-weekly alendronate or…
- Trial name
- NCT02604836
- Testing
- Ibandronate
- Where
- 142 sites in United States
- Volunteers
- 1,711 people
- Sponsor
- Hoffmann-La Roche
Breast Cancer
Simultaneous Versus Sequential Use of Adjuvant Chemotherapy and GnRHa in Treating ER+,Premenopausal Breast Cancer
The present study is a randomized open-label -phase III study that aims to compare the efficacy and safety of the adjuvant chemotherapy with simultaneous or sequential application of Zoladex up to 2-3 years for ≤ 45 year old…
- Trial name
- NCT01712893
- Testing
- Zoladex
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Fudan University
Menopause, Opportunistic Salpingectomy
Menopausal Impact of Opportunistic Salpingectomy for Ovarian Cancer Prevention
The goal of this clinical trial is to find out whether removing the fallopian tubes at the time of hysterectomy leads to an earlier menopause.
- Trial name
- MISSION-O (NCT07423143)
- Testing
- Opportunistic salpingectomy
- Where
- Sweden
- Volunteers
- 2,100 people
- Sponsor
- Umeå University
Genitourinary Syndrome of Menopause
Laser Therapy for Treatment of Genitourinary Syndrome of Menopause (GSM) in Postmenopausal Women
This is a prospective, multi-centre, double blinded, randomized controlled trial, which will be conducted under a common protocol.
- Trial name
- LASER_2022 (NCT05305209)
- Testing
- Intervention group, Control Group
- Where
- Spain
- Volunteers
- 189 people
- Sponsor
- University of Malaga
Vaginal Atrophy, Atrophic Vaginitis
ASSIST-VLA: Assessment of Symptom-Specific Improvement in Diagnosed Vaginal Atrophy Following Laser Therapy
Vaginal atrophy patients receiving vaginal laser therapy will be treated with daily 7-0940® following a laser session to evaluate the safety and efficacy of the product as an adjunct treatment.
- Conditions
- Vaginal Atrophy, Atrophic Vaginitis, Genitourinary Syndrome of Menopause (GSM)
- Trial name
- ASSIST-VLA (NCT07346287)
- Testing
- 7-940
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Stratpharma AG
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