Clinical trials: Menopause
Menopause, Platelet-rich Plasma
Compare Vaginal Estrogen and Platelet-rich Plasma Over Women With Genitourinary Syndrome of Menopause
The definition of Genitourinary Syndrome of Menopause (GSM) is the decline of estrogens during menopause results in symptoms and clinical signs from both systems.
- Conditions
- Menopause, Platelet-rich Plasma, Estrogen Replacement Therapy, Vaginal Atrophy
- Trial name
- NCT05483634
- Testing
- Vaginal estrogen supplement, Platelet-rich plasma injection
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Mackay Memorial Hospital
Breast Cancer
S1222 Trial (Everolimus, Anastrozole and Fulvestrant) in Post-Menopausal Stage IV Breast Cancer
This randomized Phase III trial studies how well the combination of fulvestrant and everolimus together or the combination of anastrozole, fulvestrant and everolimus together, improve progression-free survival (PFS) versus…
- Trial name
- NCT02137837
- Testing
- Fulvestrant, Anastrozole, Everolimus
- Where
- 223 sites in United States
- Volunteers
- 37 people
- Sponsor
- SWOG Cancer Research Network
Breast Cancer, Breast Cancer Mortality
Influence of Lifestyle, Inflammatory Biomarkers, and Genetic Factors on Long-term Breast Cancer Prognosis
The MARIEplus study is a prospective cohort of breast cancer patients recruited into the MARIE (Mamma Carcinoma Risk factor InvEstigation) study, a population-based case-control study of breast cancer conducted in two German…
- Conditions
- Breast Cancer, Breast Cancer Mortality, Breast Cancer Survival, Postmenopausal Breast Cancer
- Trial name
- NCT03401034
- Volunteers
- 3,813 people
- Sponsor
- German Cancer Research Center
Ductal Breast Carcinoma In Situ, Estrogen Receptor Negative
Radiation Therapy in Treating Post-Menopausal Women With Early Stage Breast Cancer Undergoing Surgery
This phase II trial studies how well radiation therapy works in treating post-menopausal women with early stage breast cancer undergoing surgery. Radiation therapy uses high energy x rays to kill tumor cells.
- Conditions
- Ductal Breast Carcinoma In Situ, Estrogen Receptor Negative, Estrogen Receptor Positive, HER2/Neu Negative
- Trial name
- NCT01754519
- Testing
- Therapeutic Conventional Surgery, Radiation Therapy, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Roswell Park Cancer Institute
Menopause, Hot Flashes
Applied Relaxation for Vasomotor Symptoms
The objectives of this study are to compare frequency and severity of moderate to severe vasomotor symptoms in postmenopausal women treated with applied relaxation (AR) with an untreated control-group (CG) and to investigate if…
- Trial name
- NCT01488864
- Testing
- Applied Relaxation (AR)
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Elizabeth Nedstrand
Post-Menopausal Osteoporosis
A Study of Bonviva (Ibandronate) in Women With Post-Menopausal Osteoporosis Who Have Received Previous Bonviva Treatment
This 2-arm study was designed to assess the long-term safety and tolerability of intravenous (IV) treatment with 2 mg or 3 mg Bonviva in women with post-menopausal osteoporosis who had previously completed Bonviva study BM16550…
- Trial name
- NCT00551174
- Testing
- ibandronate [Bonviva/Boniva]
- Where
- 39 sites in United States, Australia and 13 more
- Volunteers
- 781 people
- Sponsor
- Hoffmann-La Roche
Menopause, Perimenopause
Hop Extract Versus Soy Isoflavone Extract for Menopausal Symptoms (HOPES)
HOPES (Hops On Psychological and Estrogenic Symptoms in Menopause) is a randomized, double-blind, active-controlled nutritional intervention study in 120 peri- and postmenopausal women aged 45 to 60 years with moderate to severe…
- Conditions
- Menopause, Perimenopause, Postmenopause
- Trial name
- HOPES (NCT07904390)
- Testing
- Full Spectrum hop extract (MENODUO FullSpectrum), Soy isoflavone extract
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Menoclinica by Palacios
Infertility (IVF Patients)
Human Menopausal Gonadotropin Research in Infertility Assessing Cumulative Live Birth With Frozen Embryo Transfer.
The goal of this multicenter, randomized, placebo-controlled, double-blind clinical trial is toto evaluate the efficacy and safety of a human menopausal gonadotropin (hMG) in the development of multiple follicles, pregnancy, and…
- Trial name
- GRACE (NCT07216742)
- Testing
- hMG subcutaneous injection
- Where
- 16 sites in United States
- Volunteers
- 659 people
- Sponsor
- Granata Bio Corporation
Geriatrics Balance Disturbance With High Risk Falling, Osteoporosis, Vestibular Age Related Changes, Female Post-menopausal Based on History
Monitoring Combined Effect of Balance and Strengthening Exercises on Static and Dynamic Balance in Elderly Populations
The purpose of training is to evoke improvements in reactive balance, then the training program may be associated with all postural control systems, including the musculoskeletal system, the cognitive system, as well as the…
- Trial name
- NCT06835413
- Testing
- 1-Balance Exercises A- Standing with a decreased base B- Graded reaching in standing C- Stepping in different directions D- Walking practice 2-Strength and Balance Exercises A- Sit-to-stand B- Heel r
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- South Valley University
Menopause
Perception and Knowledge About Menopause Among Pakistani Woman
This study is conducted to find out perception and knowledge about Menopause among Pakistani Woman.
- Trial name
- NCT03506269
- Where
- Pakistan
- Volunteers
- 910 people, healthy volunteers welcome
- Sponsor
- OBS Pakistan
Menopause, Psychological Stress
Effect of Mandala Coloring on Menopausal Attitude, Perceived Stress and Mindfulness
Menopause is a natural life stage associated with hormonal changes that may affect women physically and psychologically. During this period, women may experience increased stress levels, negative attitudes toward menopause, and…
- Conditions
- Menopause, Psychological Stress, Mindfulness
- Trial name
- MANDALA-MENO (NCT07657429)
- Testing
- Mandala Coloring Program, Routine Care
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Ondokuz Mayıs University
Quality of Life and Menopause
Effects of Chi Kung to Improve the Symptoms of Menopause
To analyze the effects of a Chi Kung exercise program in Spanish menopausal women
- Trial name
- NCT03989453
- Testing
- Chi Kung
- Where
- Spain
- Volunteers
- 117 people
- Sponsor
- University of Jaén
Female Urogenital Diseases, Vaginal Atrophy
Investigation of Microbiomes of Postmenopausal Women Looking for Outcomes and Response to Estrogen Therapy
In this proposed pilot study, 16S ribosomal RNA (rRNA) gene sequencing will be used in the analysis of bacterial communities (microbiomes) in postmenopausal women with vulvovaginal atrophy (VVA) before and after eight weeks of…
- Conditions
- Female Urogenital Diseases, Vaginal Atrophy, Postmenopausal Atrophic Vaginitis, Genitourinary Disease
- Trial name
- IMPLORE (NCT03996603)
- Testing
- Conjugated Estrogens Cream
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Alabama at Birmingham
Hypertension, Menopause
The Effects of Stair Climbing on Arterial Stiffness, Blood Pressure and Leg Strength in Stage-1 Postmenopausal Women
We used a parallel experimental design. Following an initial screening and familiarization session of study tests and procedures, eligible postmenopausal women were randomly assigned to a stair climbing (SC) group or…
- Trial name
- NCT03254251
- Testing
- Stair climbing
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Pusan National University
Perimenopause, Menopausal Complaints
Amygdala Insula Retraining in the Management of Perimenopause Symptoms
The goal of this study is to evaluate a neuroplasticity-based mind-body intervention, Amygdala and Insula Retraining (AIR), compared to a wait-list control in individuals experiencing perimenopausal symptoms.
- Trial name
- NCT07427459
- Testing
- Amygdala and Insula Retraining (AIR)
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Chronic Conditions Research Fund
Hypoactive Sexual Desire Disorder (HSDD)
Prasterone (DHEA) for the Treatment of Hypoactive Sexual Desire Disorder (HSDD) - Second Study
The primary objective is to confirm the efficacy of intravaginal prasterone (DHEA) on Hypoactive Sexual Desire Disorder (HSDD) in postmenopausal women.
- Trial name
- NCT03619005
- Testing
- Prasterone 6.5 mg (0.50%) Vaginal Insert
- Where
- 10 sites in United States
- Sponsor
- EndoCeutics Inc.
Healthy
A Food Effect Study With ZN-c5 in Healthy Post-Menopausal Subjects
This is a single-center, randomized, open-label, two-period, 2-way crossover food effect study to determine the comparative bioavailability of ZN-c5 under fed and fasting conditions, following single-dose administration of ZN-c5…
- Trial name
- NCT04561752
- Testing
- ZN-c5
- Where
- New Zealand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zeno Alpha Inc.
Menopause
Effects of Balance Exercises With and Without Clamshell Exercises After Menopause
Exercise-based balance intervention is structured program of physical exercises intended to enhance balance, stability, and clamshell exercises are known as an exercise-based balance intervention.
- Trial name
- NCT06750263
- Testing
- Balance exercise with clamshell, Balance exercise
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Post Menopause
High Intensity Resistance Training In Postmenopausal Women (HIRT)
Menopause is defined as a permanent cessation of menstrual cycle for 12 months due to intrinsic diminution of ovarian oocytes among women in older age.
- Trial name
- HIRT (NCT05052749)
- Testing
- High Intensity Resistance Training (HIRT), Low-moderate Resistance Exercise Training
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Anxiety Disorder/Anxiety State, Depressive Disorder/Psychology
Adapting Mental Health Interventions for War-Affected Youth Through Employment Programs
The research will first examine data obtained from YRI participants to investigate effects of the group sessions on psychosocial functioning outcomes in youth aged 15 - 24.
- Conditions
- Anxiety Disorder/Anxiety State, Depressive Disorder/Psychology, Social Problems/Psychology, Violence, Non-accidental
- Trial name
- NCT02561949
- Testing
- YRI, Income generating activity program
- Where
- Sierra Leone
- Volunteers
- 80 people
- Sponsor
- Boston College
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