Clinical trials: Menopause
Endometriosis
Safety and Efficacy of Telapristone Acetate (Proellex®) in the Treatment of Pre-Menopausal Women With Confirmed, Symptomatic Endometriosis
The primary purpose of this study is to determine the safety and efficacy of two oral doses of telapristone acetate administered to premenopausal women with pelvic pain associated with endometriosis confirmed within the last…
- Trial name
- NCT01728454
- Testing
- Telapristone acetate
- Where
- 10 sites in United States
- Volunteers
- 60 people
- Sponsor
- Repros Therapeutics Inc.
Bone Diseases, Metabolic, Diabetes Mellitus, Type 2
A Clinical Trial to Evaluate the Bone Metabolism and the Blood Sugar of Evogliptin and Dapagliflozin
This multi-center, randomized and exploratory clinical trial is designed to evaluate the effect of bone metabolism and blood sugar of evogliptin and dapagliflozin in the menopause female patients with osteopenia and type 2…
- Trial name
- EVOMETA (NCT04706637)
- Testing
- Evogliptin, Dapagliflozin
- Where
- 7 sites in South Korea
- Volunteers
- 120 people
- Sponsor
- Kyung Hee University Hospital at Gangdong
Menopausal Symptoms
European Active Surveillance Study of Women Taking Hormone Replacement Therapy (HRT)
The objective of the active surveillance study is to compare incidence rates of serious adverse events in users of all types of newly prescribed oral continuous combined HRT products.
- Trial name
- NCT00214903
- Where
- Germany
- Volunteers
- 30,597 people
- Sponsor
- Center for Epidemiology and Health Research, Germany
Turner Syndrome, Ovarian Failure, Premature
Dry Eye in Women With Turner Syndrome and Women With Premature Ovarian Failure
Premature ovarian failure (POF) is known to be associated with an increased risk of ocular surface disease (dry eye), likely due to the reduction of both estrogens and androgens seen in this condition.
- Conditions
- Turner Syndrome, Ovarian Failure, Premature, Sex Chromosome Aberrations, Menopause
- Trial name
- NCT00471731
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Menopausal Syndrome
The Effect of Acupressure Application on Menopausal Symptoms
The study was conducted randomly controlled to determine the effect of acupressure application on menopausal complaints among women who applied to Cancer Early Diagnosis and Screening Center.
- Trial name
- NCT04520542
- Testing
- Acupressure Application
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Adiyaman University Research Hospital
Menopause
MyHealtheVet to Enable Shared Decision Making Regarding Menopausal in Postmenopausal Women Veterans (MEANS)
The purpose of this research study is to examine the impact of educational secure messages on menopause. In particular, the investigators will examine whether the secure messages increase menopause knowledge and communication…
- Trial name
- MEANS (NCT03109145)
- Testing
- Menopause educational secure messaging
- Where
- United States
- Volunteers
- 859 people, healthy volunteers welcome
- Sponsor
- Miami VA Healthcare System
Breast Cancer
A Study of LY3484356 in Women With Breast Cancer Before Having Surgery
The purpose for this study is to see if the study drug, LY3484356, is safe and to determine what effects it has on breast cancer in participants with Estrogen Receptor Positive (ER+), HER2 Negative (HER2-) early stage (stage…
- Trial name
- EMBER-2 (NCT04647487)
- Testing
- LY3484356
- Where
- 19 sites in United States, Belgium and 4 more
- Volunteers
- 87 people
- Sponsor
- Eli Lilly and Company
Breast Cancer
CONcurrent vs SEqueNTial Adjuvant Treatments in Early Breast Cancer
Breast cancer is the most common form of cancer among women. For patients candidated for adjuvant chemotherapy and endocrine therapy the optimal timing for their has not been clearly defined yet.
- Trial name
- GIM10-CONSENT (NCT02918084)
- Testing
- Anastrozole or Letrozole or Exemestane
- Where
- 74 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
Postmenopausal Bone Loss, Breast Cancer
A Pilot Study of Bone Mineral Density in Postmenopausal Women After Treatment for Breast Cancer
The main purpose of this study is to see what levels of Bone Mineral Density post-menopausal women with breast cancer have, and to see if the level of Bone Mineral Density changes during a women's treatment after her surgery.
- Trial name
- NCT00399321
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Michigan Rogel Cancer Center
Vasomotor Symptoms (VMS)
Safety and Efficacy Study of AR08 for the Treatment of Vasomotor Symptoms (VMS)
The purpose of this study is to determine the effective dose or dose range of AR08 in the treatment of VMS in menopausal females.
- Trial name
- NCT02049164
- Testing
- AR08
- Where
- 15 sites in United States
- Volunteers
- 32 people
- Sponsor
- Arbor Pharmaceuticals, Inc.
Menopause, Aging
The Effect of Education on Vaginal Effects of Menopausal Women
The aim of our study is to examine the effect of education applied to women in menopause on the daily effects of vaginal aging, avoidance of sexuality and sexual stress.
- Conditions
- Menopause, Aging, Failure of Genital Response
- Trial name
- NCT06095193
- Testing
- menopause education
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Gaziantep Islam Science and Technology University
Breast Cancer
Prevention Strategy for Pre-Menopausal Women at High Risk for Development of Breast Cancer
The investigators will study the effect of 12 months of SDG (Brevail) vs placebo on women at increased risk for development of breast cancer.
- Trial name
- NCT01276704
- Testing
- secoisolariciresinol
- Where
- 7 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Carol Fabian, MD
Menopausal Symptoms
A Clinical Trial on the Efficacy of a Combination Herbal Product, Biotropics' Nu Femme, on Menopausal Symptoms and Quality of Life in Women
The purpose of this study is to assess the effectiveness of an herbal combination product called Nu Femme, on menopausal symptoms in peri-menopausal women.
- Trial name
- 14NMHB (NCT02269891)
- Testing
- Nu Femme
- Where
- 4 sites in Canada
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- KGK Science Inc.
Osteopenia
Safety Study of an Oral Pro-boneTM, Administered to Post Menopausal Osteopenic Women
Recent studies have shown that inhibition of Aquaporine-9 channels may ameliorate the bone degradation process. Pro-bone is an AQ - 9 channels inhibitor. This study is design to evaluate the safety of Pro-bone.
- Trial name
- NCT01397838
- Testing
- Pro-Bone
- Volunteers
- 20 people
- Sponsor
- OsteoBuild Ltd.
Menopausal Women
Foot Massage for Women With Menopause
This study will be carried out to determine the effect of foot massage applied to menopausal women on anxiety, fatigue and sleep levels.
- Trial name
- NCT05212376
- Testing
- Foot massage
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Inonu University
Healthy
Phase I Study to Evaluate the Safety and Efficacy of MF101 as Well as the Pharmacokinetics of Its Key Active Components
This Phase I trial in healthy, post-menopausal women is designed as a double-blind, placebo-controlled, randomized, ascending single-dose safety trial.
- Trial name
- NCT00453297
- Testing
- MF101
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bionovo
Urinary Incontinence , Stress
Pelvic Floor Muscle Training vs. Pilates Exercises for Urinary Incontinence
Urinary incontinence (UI) affects approximately 40% of postmenopausal women and is therefore considered a public health problem.
- Trial name
- NCT07212478
- Testing
- PFMT, Pilates exercises
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Universidade Estadual do Norte do Parana
Postmenopausal, Vitamin D Deficiency
Study to Observe the Capability to Absorb Calcium as an Measure of Adequate Levels of Vitamin D
The purpose of this study is to determine the capability to absorb calcium as a measure of the sufficient levels of Vitamin D. Calcium absorption will be measured at baseline and after vitamin D3, by dual calcium isotope…
- Trial name
- NCT01119378
- Testing
- Dual isotope technique
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Winthrop University Hospital
Infertility, Female
Androgenic Profile Following Controlled Ovarian Stimulation
In this study the investigators will try to discover whether there is a difference for any of the stimulation preparations - recombinant FSH + recombinant LH (pergoveris \& luveris) vs.
- Trial name
- NCT02992808
- Testing
- recombinant gonadotropins, HP-HMG
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Healthy
Estradiol/Norethindrone Acetate Tablets, 1/0.5 mg Under Fed Conditions
The objective of this study was to determine and compare the rate and extent of absorption of norethindrone and unconjugated estradiol from a test formulation of Estradiol/Norethindrone Acetate Tablets, 1 mg/0.5 mg versus the…
- Trial name
- NCT01181726
- Testing
- Estradiol/Norethindrone acetate, Activella®
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Teva Pharmaceuticals USA
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