Clinical trials: Menopause
Hot Flashes, Night Sweats
Applied Relaxation (AR) Technique Versus Its Modified Version for Treating Menopausal Symptoms
The purpose of this study is to demonstrate better efficacy and effectiveness of modified applied relaxation technique over its original version for treating menopausal symptoms.
- Conditions
- Hot Flashes, Night Sweats, Sleep Disturbances
- Trial name
- NCT01429636
- Testing
- Modified Relaxation (MR), Applied Relaxation (AR)
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Chiang Mai University
Menopause
A Randomized-Controlled Trial to Examine the Effects of a Daily Probiotic Supplement on Common Symptoms of Menopause
Symptoms of menopause can significantly affect overall quality of life. It is hypothesized that probiotic supplements can reduce the severity of these symptoms.
- Trial name
- NCT06148714
- Testing
- Provitalize Natural Menopause Probiotic
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maneuver Marketing
Hot Flashes
A Study to Find the Best Dose of Fezolinetant to Treat Hot Flashes in Women Going Through Menopause
This study is for menopausal women who have hot flashes. Menopause, a normal part of life, is the time after a woman's last period. Hot flashes often occur during menopause. They can disrupt a woman's daily life.
- Trial name
- Starlight (NCT05034042)
- Testing
- Fezolinetant
- Where
- 40 sites in Japan
- Volunteers
- 147 people
- Sponsor
- Astellas Pharma Inc
Contraception, Menopause
Safety, Tolerability and Pharmacokinetics of Estetrol (E4) After Single and Multiple Oral Doses in Healthy Female Volunteers
Estetrol (E4) is being developed in two indications supporting women health care: first E4 is combined with a progestin, [drospirenone (DRSP)] and is used as a new combined oral contraceptive (COC) for the prevention of pregnancy…
- Trial name
- NCT03075956
- Testing
- 5 mg E4 single-dose, 15 mg E4 single-dose, 45 mg E4 single-dose
- Where
- Bulgaria
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Estetra
Menopause
Efficacy and Safety of Estradiol and Progesterone Microspheres for the Treatment of Climacteric Symptoms.
During menopause a woman's body slowly produces less of the hormones estrogen and progesterone. Lower hormone levels in menopause may lead to hot flashes, vaginal dryness and osteoporosis.
- Trial name
- NCT00775242
- Testing
- Estradiol and Progesterone
- Where
- Mexico
- Volunteers
- 103 people
- Sponsor
- Centro A.F. de Estudios Tecnologicos, S.A.
Menopause, Stress Urinary Incontinence
Pelvic Floor Muscle Exercises and Core Exercises in Menopausal Women
The prospective and four-arm randomized controlled study was conducted on n = 136 (34 = control, 34 = kegel, 34 = core, 34 = kegel+ core group) menopausal women at Trakya University Health Research and Application Center Urology…
- Conditions
- Menopause, Stress Urinary Incontinence, Kegel Exercises, Core Strength
- Trial name
- NCT06348342
- Testing
- Pelvic Floor Muscle Exercise, Core Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 136 people
- Sponsor
- Trakya University
Obesity
Thermogenenic Responses to Fasting and Overfeeding in Women
This study plans to learn more about why menopause increases the risk of weight gain. During and after menopause, women are prone to increased weight gain.
- Trial name
- NCT06610162
- Testing
- Eucalaloric feeding, Acute Fasting, Acute Overfeeding
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obesity, Menopause
A Cohort Research of Genetic Susceptibility for Common Obesity in Women
Not many studies examined genetic determinants of obesity in women. As pre-menopausal and post-menopausal women appear to have different propensities for fat deposition, genetic loci linked with obesity-related phenotypes might…
- Trial name
- CROWN (NCT01488903)
- Where
- Taiwan
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Breast Cancer
PROACT - Pre-Operative Arimidex Compared To Tamoxifen
The purpose of this study is to compare tamoxifen, versus a newer treatment, ARIMIDEX, which we already know to be well tolerated.
- Trial name
- NCT00232661
- Testing
- ARIMIDEX (anastrazole), NOLVADEX (tamoxifen)
- Where
- 79 sites in United States, Belgium and 8 more
- Volunteers
- 452 people
- Sponsor
- AstraZeneca
Postmenopausal, Menopausal Symptoms
Structured Combined Exercise Program in Postmenopausal Women: Effects on Heart Rate Variability and Menopausal Symptoms
The goal of this clinical trial is to learn whether a structured combined exercise program can improve heart health, menopausal symptoms, sleep quality, and quality of life in postmenopausal women aged 45 to 65 years.
- Conditions
- Postmenopausal, Menopausal Symptoms, Autonomic Nervous System Diseases, Sleep Wake Disorders
- Trial name
- NCT07615790
- Testing
- Structured Combined Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Fenerbahce University
Osteoporosis, Post-Menopausal
PTH Comparison in Post Menopausal Women
Compare in postmenopausal women with established osteoporosis the effect of treatment with teriparatide 20 micrograms/day subcutaneous with the effect of salmon calcitonin 100 IU/day subcutaneous on change in lumbar spine BMD.
- Trial name
- NCT00543218
- Testing
- teriparatide 20 micrograms/day subcutaneous, calcitonin 100 IU/day subcutaneous
- Where
- 4 sites in Taiwan
- Volunteers
- 63 people
- Sponsor
- Eli Lilly and Company
Breast Cancer, Cancer Survivor
Magnesium Oxide in Treating Hot Flashes in Menopausal Women With Cancer
RATIONALE: Magnesium oxide may help relieve hot flashes in women with cancer. PURPOSE: This phase II trial is studying how well magnesium oxide works in treating hot flashes in menopausal women with cancer.
- Conditions
- Breast Cancer, Cancer Survivor, Hot Flashes, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT01008904
- Testing
- magnesium oxide, questionnaire administration, quality-of-life assessment
- Volunteers
- 31 people
- Sponsor
- Virginia Commonwealth University
Menopause, Postmenopausal Bone Loss
Effects of Tibilone on Bone Density, Menopause Symptoms and Breast Density in Women After Prophylactic Oophorectomy
Women undergoing surgical menopause often experience marked menopausal side effects but are reluctant to use estrogen or other female hormones to ease the transition to menopause because of worries that the hormones may increase…
- Conditions
- Menopause, Postmenopausal Bone Loss, Breast Cancer
- Trial name
- NCT00165204
- Testing
- Tibolone
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Dana-Farber Cancer Institute
Obesity, Sarcopenia
Chrono-restricted Diet and Physical Activity as a New Preventive Strategy for Sarcopenia in Postmenopausal Women With Obesity and Type 2 Diabetes
The aim of TIMEDIAB is to demonstrate that early TRE (eTRE) combined to late (afternoon) exercise will outperform eTRE combined to morning exercise on muscle function as primary endpoint, and glucose homeostasis as secondary…
- Conditions
- Obesity, Sarcopenia, Post Menopause, Type 2 Diabetes
- Trial name
- TIMEDIAB (NCT07075133)
- Testing
- Antidiabetic diet (control), eTRE diet, Physical activity in the morning
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Menopause
Milk on Gut Microbiome and Bone Remodeling CTX in Postmenopausal Women
Milk consumption drives beneficial effect on Bone Mass Density and on Gut Microbiome. Altered Gut Microbiome is associated with postmenopausal status, reduced Bone Mass Density, abnormal serum levels of Bone Turnover Markers…
- Trial name
- Milk-CTX-GM (NCT06050018)
- Testing
- YesMilkdiet, NoMilkdiet
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University
Menopause
A Study To Investigate The Effect Of A Natural Dietary Supplement On Peri-Menopausal Symptoms
This is a randomized, masked, placebo controlled study to assess the effect on a nutritional dietary supplement on menopausal signs and symptoms in perimenopausal women.
- Trial name
- NCT02497560
- Testing
- proprietary formula
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Physician Recommended Nutriceuticals
Depressive Disorder, Major, Menopause
Estrogen and Perimenopausal Depression
During perimenopause (the time just prior to menopause), women often notice many biological, psychological, and social changes. In particular, some women experience depressive symptoms during perimenopause that are severe enough…
- Trial name
- NCT00229450
- Testing
- Estrogen
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of California, Los Angeles
Sleep Disturbances and Insomnia
Effect of Resistive Exercise on Insomnia in Post Menopausal Women
the aim of this study is to investigate the efficacy of resistive exercise on insomnia in post menopausal women
- Trial name
- NCT05556317
- Testing
- Resistive exercise
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Cairo University
Menopause, Postmenopausal State
THE EFFECT OF MOTIVATIONAL INTERVIEWING ON MENOPAUSE MYTHS AND POSTTRAUMATIC GROWTH IN POSTMENOPAUSAL WOMEN:RANDOMIZED CONTROLLED STUDY
This randomized controlled study aims to evaluate the effect of motivational interviewing on menopause myths and posttraumatic growth in postmenopausal women.
- Trial name
- NCT07596368
- Testing
- Motivational interviewing
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Inonu University
Post Menopausal Dry Eye Subjects
Efficacy of Systane Ultra in Post Menopausal Women With Dry Eye
To evaluate the efficacy of Systane Ultra in post menopausal women with dry eye.
- Trial name
- NCT01105910
- Testing
- Systane Ultra Lubricant Eye Drops, Sensitive Eyes Eye Drops (Bausch & Lomb)
- Volunteers
- 70 people
- Sponsor
- Alcon Research
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