Clinical trials: Menopause
Menopause, Postmenopausal Vaginal Atrophy
Comparison of Two Vaginal Tablets, Produced at Different Sites, in Postmenopausal Women With Atrophic Vaginitis
This trial is conducted in Europe. The aim of this trial is to compare the absorption of estradiol after a single dose of two 25 mcg estradiol vaginal tablets, produced at two different production sites, in postmenopausal women…
- Trial name
- NCT01085877
- Testing
- estradiol, 25 mcg
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Novo Nordisk A/S
Early Menopause, Menopause
Influence of Early Menopause on Sympathetic Activation and Cardiovascular Function in Older Women
Women who enter menopause early are at a greater risk for developing cardiovascular disease later in life as compared to women with normal onset of menopause.
- Trial name
- NCT03692572
- Testing
- Nitrate supplementation
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Osteoarthritis, Knee, Prosthesis User
Characteristics of Marrow Fatty Cells in the Ageing of Bone and Joints, Osteoarthritis and Osteoporosis
Obesity and other associated complications promote the development and the progression of osteoarthritis. The subcutaneous and abdominal fat release several factors that alter bone and the cartilage.
- Trial name
- MEDADIPO (NCT03678831)
- Testing
- tissue
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Lille
to Assess Changes in Body Composition After Dietary Supplementation With Sinetrol
A Randomized, Double-blind, Placebo-controlled, Parallel Study to Assess the Effect of Sinetrol on Body Composition &Metabolic Health in Peri-menopausal/Early Menopausal Women
The menopausal transition is associated with significant hormonal and metabolic changes, primarily driven by a decline in estrogen levels.
- Trial name
- MENOFIT (NCT07782853)
- Testing
- dietary supplementation
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- DR Healthcare - biotexia
Coronary Artery Disease (CAD), Menopause
Serum Endogenous Estrogens, Estrogen Receptors, and Sirtuin-1 and -3 After Resveratrol Supplementation
Atherosclerotic coronary artery disease (CAD) is a leading cause of mortality among postmenopausal women. Resveratrol, a phenolic compound with antioxidant properties, may influence lipid metabolism, endothelial function, and…
- Conditions
- Coronary Artery Disease (CAD), Menopause, Hormones
- Trial name
- RESEARCH (NCT07865377)
- Testing
- Trans-resveratrol, 1000 mg daily for 90 days
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- InCor Heart Institute
Breast Cancer, Cancer of the Breast
Comparing Letrozole Given Alone to Letrozole Given With Avastin in Post-Menopausal Women Breast Cancer
This purpose of this trial is to show that the combination of Avastin and hormone therapy should be more effective than hormone therapy alone for the treatment of breast cancer.
- Conditions
- Breast Cancer, Cancer of the Breast, Breast Neoplasm
- Trial name
- NCT00530868
- Testing
- Letrozole (Femara), Letrozole; Avastin
- Where
- 7 sites in United States
- Volunteers
- 75 people
- Sponsor
- University of Alabama at Birmingham
Hypoactive Sexual Desire Disorder
Study of Transdermal Testosterone Patches in Surgically Menopausal Women With Low Libido
This study is designed to evaluate efficacy and safety of a testosterone patch as treatment for low libido in surgically menopausal women who are taking estrogen therapy.
- Trial name
- NCT00331123
- Testing
- Testosterone Transdermal System
- Where
- 3 sites in United States, Australia and 1 more
- Volunteers
- 562 people
- Sponsor
- Warner Chilcott
Post Menopausal Osteoporosis
ExBonAdAsia Study: A Study of Once Monthly Bonviva (Ibandronate) in Women With Post-Menopausal Osteoporosis.
This single arm study will continue drug safety surveillance, and assessment of adherence, in patients with postmenopausal osteoporosis who have received monthly oral Bonviva in ML19930, the BonAdAsia study.
- Trial name
- NCT00545090
- Testing
- ibandronate [Bonviva/Boniva]
- Where
- 17 sites in Hong Kong, Indonesia and 3 more
- Volunteers
- 561 people
- Sponsor
- Hoffmann-La Roche
Menopause
The Impact of Laughter Yoga on Symptom Management and Quality of Life in Postmenopausal Women
This study aimed to assess the impact of laughter yoga intervention on symptomatology and quality of life among postmenopausal women.The research was conducted in a randomized controlled experimental design.
- Trial name
- NCT06579118
- Testing
- Laughter yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Infertility, Polycystic Ovary Syndrome
A New Algorithm to Predict Ovarian Age
To collect data of clinical, biochemical and 3D-ultrasonographic parameters of a population of fertile women aged 18-55 in order to design a new algorithm able to predict ovarian age and to evaluate the reliability of a…
- Conditions
- Infertility, Polycystic Ovary Syndrome, Premature Ovarian Failure (POF), Ovarian Cysts
- Trial name
- OvAge (NCT02086318)
- Testing
- OvAge assessment
- Where
- Italy
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Exercise Training, Post-menopausal Women
Stem Cell Recruitment in Exercised Skeletal Muscles of Older Women by Phytosteroid Rg1
The goal of this interventional study is to observe the effects of bone marrow stem cell behavior in skeletal muscle of women between 60 to 75 years old after a single moderate resistance exercise session.
- Conditions
- Exercise Training, Post-menopausal Women, Bone Marrow Stem Cells, Skeletal Muscle Recovery
- Trial name
- NCT07093190
- Testing
- exercise following Rg1 consumption
- Where
- Taiwan
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Taipei
Hot Flashes
Breathe for Hot Flashes Randomized Controlled Trial
Background: Paced respiration has been internationally recommended for vasomotor symptom management despite limited empirical evidence.
- Trial name
- NCT00819182
- Testing
- Paced respiration
- Where
- United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Indiana University
Hot Flashes
Soy Isoflavone Tablets: Effects on Sleep, Quality of Life, Symptoms and Cognitive Function in Menopausal Women
The study was done to elucidate relationships between midlife women's self-reported hot flashes, neuropsychological symptoms, cognitive performance or sleep.
- Trial name
- NCT01401946
- Testing
- soy isoflavones
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Hot Flashes, Sleep
LINE-1 and Alu Methylation Levels Among Middle Aged Women With Low Cardiovascular Risk Profile in Respect of Menopausal Hot Flashes
Vasomotor symptoms are the most common symptoms seen during climacterium. The hypoestrogenic state causes dysfunction of hypothalamic preoptic area, a thermoregulatory center.
- Conditions
- Hot Flashes, Sleep, Menopause, Cardiovascular Diseases
- Trial name
- NCT05892211
- Testing
- Polysomnography, Skin conductance, ALU and LINE-1 DNA methylation analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Breast Neoplasms
PTK and Letrozole in Post-menopausal Women With Advanced Breast Cancer
The purpose of this study is to test the safety of PTK787/ZK222584 and Letrozole when given in combination, and to see what effects they have on breast cancer that has metastasized.
- Trial name
- NCT00263198
- Testing
- PTK787/ZK222584, Letrozole
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Washington University School of Medicine
Breast Cancer, Menopausal Symptoms
Effect of a Brassicaceae-Enriched Diet on Menopausal Symptoms in Women With Breast Cancer Receiving Antiestrogen Therapy
This study aims to evaluate whether increasing the intake of Brassicaceae vegetables may help reduce menopausal symptoms in women with hormone-sensitive breast cancer who are receiving adjuvant antiestrogen therapy.
- Trial name
- BRASSICA (NCT07842614)
- Testing
- Increased Dietary Intake of Brassicaceae Vegetables
- Where
- Italy
- Volunteers
- 81 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Severe Vasomotor Symptom Associated With Menopause
Post Marketing Surveillance To Observe Safety And Efficacy Of Duavive
To evaluate safety and efficacy of CE/BZA in real practice in Korea
- Trial name
- NCT02792504
- Where
- 20 sites in South Korea
- Volunteers
- 669 people
- Sponsor
- Pfizer
Menopausal Syndrome
A Real-world Clinical Study on the Treatment of Menopausal Syndrome With Liuwei Dihuang Pills
To evaluate the clinical efficacy of the real-world Liuwei Dihuang pills for the treatment of female menopausal syndromes, and to provide a basis for effective, safe and rational clinical use of the drug.
- Trial name
- NCT06874738
- Testing
- Liuwei Dihuang pills
- Volunteers
- 1,000 people
- Sponsor
- China Academy of Chinese Medical Sciences
Cryopreservation, Ovary Injury
Improving the Quality of Cryopreserved Ovarian Tissue Reimplantation Using Platelet-enriched Autologous Plasma
The study is aimed to evaluate the effects of intraovarian injection of autologous Platelet-enriched Autologous Plasma on the outcomes of orthotopic transplantation of cryopreserved ovarian tissue.
- Conditions
- Cryopreservation, Ovary Injury, Infertility, Female, Menopause Ovarian Failure
- Trial name
- TESOVA2022 (NCT06261658)
- Testing
- Cryopreserved Ovarian Tissue Reimplantation
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Laxity; Skin
Evaluate the Safety and Efficacy of a Topical Serum (AGE Serum) in Improving Visible Signs of Aging
The primary objective is to evaluate the safety and efficacy of a topical serum (AGE serum) in improving visible signs of aging (e.g., fine lines, wrinkles, sagging, texture, radiance) on the full face and neck.The study will be…
- Trial name
- NCT07216352
- Testing
- AGE Serum
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.