Clinical trials: Menopause
Female Urogenital Diseases, Urinary Incontinence
Clinical Trial of "Magic Gyno" Laser Device
The aim of this prospective study is investigation of efficiency and safety of medical device "Magic Gyno" in accordance with the stated purpose.
- Conditions
- Female Urogenital Diseases, Urinary Incontinence, Prolapse Genital, Menopausal Syndrome
- Trial name
- NCT05463081
- Testing
- Laser treatment, Blood test, Clinical urine test
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- MeLSyTech, Ltd
Osteoporosis
CR9112792, a Follow-up of Study CR9108963
The purpose of this study is to determine whether bone mineral density has increased in a subgroup of postmenopausal osteoporotic women from study CR9108963, between 6 and 12 months following cessation of ronacaleret therapy.
- Trial name
- NCT00891553
- Testing
- DXA
- Where
- 3 sites in Denmark, Norway
- Volunteers
- 171 people
- Sponsor
- GlaxoSmithKline
Menopausal Syndrome
Nanoparticulate Versus Micronized Steroids Delivery for Transdermal Hormone Replacement Therapy
The study aims to asses the effects of micronized (MIC) and nanoparticulate (NANO) transdermal hormone therapy (THT) on blood pressure, ultra-sensitive C-reactive protein (CRP), and cardiovascular risk factors in postmenopausal…
- Trial name
- Nanoparticle (NCT02467673)
- Testing
- Micronized estradiol + progesterone, Nanoparticulate estradiol + progesterone
- Where
- 3 sites in Brazil
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- University Potiguar
Cardiovascular Diseases, Coronary Disease
CHD Risk, Behavioral Stress and Reproductive Hormones
To determine the effects of behavioral stress and reproductive hormones on coronary heart disease (CHD) risk.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Menopause
- Trial name
- NCT00005538
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Post Menopausal Dry Eye Subjects
Efficacy of Systane Ultra in Post Menopausal Women With Dry Eye
To evaluate the efficacy of Systane Ultra in post menopausal women with dry eye.
- Trial name
- NCT01105910
- Testing
- Systane Ultra Lubricant Eye Drops, Sensitive Eyes Eye Drops (Bausch & Lomb)
- Volunteers
- 70 people
- Sponsor
- Alcon Research
Hot Flashes, Menopause
The Cardiovascular Impact of Hot Flushes
The overall objective of this study is to examine the physiological responses that occur during a hot flush in postmenopausal women. The following specific aims will be executed to reach the overall objective of this study.
- Trial name
- NCT05251324
- Testing
- Hot Flush Induction
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Menopause, Menopausal Symptoms
Meleis' Transition Theory-Based Education and Counseling Program in Menopausal Women
This randomized controlled trial aims to evaluate the effectiveness of a Meleis' Transition Theory-based education and counseling program on menopausal symptoms, perimenopausal depression, and menopause-specific quality of life…
- Conditions
- Menopause, Menopausal Symptoms, Perimenopausal Depression
- Trial name
- NCT07657078
- Testing
- Meleis' Transition Theory-Based Education and Counseling Program, Standard Information
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people
- Sponsor
- Ankara Medipol University
Xerostomia, Menopause
Deterioration of Resilient Denture Liners and Patient Characteristics
Thirty complete maxillary denture wearers were recruited after obtaining informed consent. One investigator measured the Shore D hardness of the commercially available RDLs using a Vesmeter®.
- Conditions
- Xerostomia, Menopause, Kidney Disease
- Trial name
- NCT02587676
- Testing
- Evatouch Super
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nihon University
Menopause
Postprandial Lipidemia After a Meal With Different Types of Fat, Estrogen Treatment, Age and Gender in Healthy Subjects
The study examines the effect of hormone replacement in postmenopausal women compared to men, 55 years of age, and in the elderly without hormone replacement of both sexes.
- Trial name
- NCT02383823
- Testing
- Estrogens
- Where
- Denmark
- Volunteers
- healthy volunteers welcome
- Sponsor
- Herning Hospital
Genitourinary Syndrome of Menopause
Use of Fractional CO2 Laser Versus Erbium:YAG Laser for the Treatment of GSM in Patients Using Aromatase Inhibitors
To study the efficacy and safety of intravaginal CO2 laser versus intravaginal Er:YAG laser and sham application in alleviating genitourinary symptoms in patients receiving an aromatase inhibitor as adjuvant treatment of breast…
- Trial name
- LASI (NCT05713435)
- Testing
- intravaginal laser
- Where
- Belgium
- Volunteers
- 162 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Breast Cancer
ITA - Clinical Study Comparing ARIMIDEX™ With NOLVADEX™ in Women With Breast Cancer Treated With NOLVADEX for at Least 2 Years
The purpose of this study was to assess the difference in disease-free survival between post-menopausal women with hormone receptor-positive early breast cancer who switched from tamoxifen to anastrozole and those who continued…
- Trial name
- NCT00286117
- Testing
- Anastrozole, Tamoxifen
- Where
- 25 sites in Italy
- Volunteers
- 448 people
- Sponsor
- AstraZeneca
Postmenopausal Osteoporosis, Gut Microbiota
Blackcurrants Modify Gut Microbiota and Reduce Osteoporosis and CVD Risk
Aim to evaluate the effects of blackcurrant supplementation on changes in gut microbiome, bone mass, and CVD risk factors in adult women.
- Conditions
- Postmenopausal Osteoporosis, Gut Microbiota, Cardiovascular Diseases
- Trial name
- NCT04431960
- Testing
- blackcurrant (BC) extract
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Menopause
Brazilian Registry of Menopausal Health
The Brazilian Registry of Menopausal Health is a national study aimed to better understand the health and quality of life of participants aged 35 to 65 who are in the menopausal transition or postmenopausal phase, including…
- Trial name
- EMBRACE (NCT07005648)
- Where
- Brazil
- Volunteers
- 1,592 people, healthy volunteers welcome
- Sponsor
- Science Valley Research Institute
Postmenopausal, Postmenopausal Disorder
Smart Technology-Based Intervention and Monitoring of Physical and Mental Health in Early Postmenopausal Women
The aim of this study is to compare the short-term and long-term effects of an 8-week home-based multimodal exercise program, delivered through a smartphone app, on quality of life, muscle function, and physical performance in…
- Conditions
- Postmenopausal, Postmenopausal Disorder, Menopause
- Trial name
- NCT07131215
- Testing
- Home-based multimodal exercise, Supervised multimodal exercise program, Education
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- YI-JU TSAI
Anxiety Disorder, Depressive Disorder
Sub-Trial of the Youth Readiness Intervention (YRI): Treatment of Control Group and Addition of Stress Biomarkers
This research is a continuation of the Youth Readiness Intervention (YRI) randomized clinical trial by adding additional pre and post intervention data collection upon treatment of the control group (N=222) with the intervention…
- Conditions
- Anxiety Disorder, Depressive Disorder, Social Problems, Stress, Psychological
- Trial name
- NCT02128568
- Testing
- Youth Readiness Intervention
- Where
- Sierra Leone
- Sponsor
- Harvard School of Public Health (HSPH)
Vasomotor Symptoms Associated With Menopause, Hot Flashes
A Study to Learn More About How Well Elinzanetant Works and How Safe it is for the Treatment of Vasomotor Symptoms (Hot Flashes) That Are Caused by Hormonal Changes Over 26 Weeks in Women Who Have Been Through the Menopause
Researchers are looking for a better way to treat women who have hot flashes after women have been through the menopause. Hot flashes are caused by the hormonal changes that happen when a woman's body has been through the…
- Trial name
- OASIS-1 (NCT05042362)
- Testing
- Elinzanetant (BAY3427080)
- Where
- 99 sites in United States, Austria and 6 more
- Volunteers
- 396 people
- Sponsor
- Bayer
BRCA Mutation, Estrogen Deficiency
A 3D Bioprinted Hormone-producing Model for BRCA Mutated Patients After Risk Reducing Surgery: the DISC-OVARY Trial
Selecting theca and granulosa cells from removed ovaries of BRCA1/2mut patients undergoing Risk-reducing salpingo-oophorectomy (RRSO) and developing a 3D bioprinted hormone-producing bioprosthetic model.
- Conditions
- BRCA Mutation, Estrogen Deficiency, Surgical Menopause, Menopause Related Conditions
- Trial name
- DISC-OVARY (NCT06497270)
- Testing
- Theca and Granulosa Cell Isolation
- Where
- Italy
- Volunteers
- 3 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Menopause, Visual Impairment and Blindness (Excl Colour Blindness)
Audio-Described Menopause Education Program in Visually Impaired Women
This randomized controlled trial was conducted to evaluate the effect of an audio-described menopause education program on menopause knowledge and menopausal symptoms in women with visual impairment.
- Conditions
- Menopause, Visual Impairment and Blindness (Excl Colour Blindness), Menopausal Symptoms, Women's Health Education
- Trial name
- NCT07771946
- Testing
- Audio-Described Menopause Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Ankara University
Metastatic Breast Cancer
Exemestane + Celecoxib vs Exemestane + Placebo in Metastatic Breast Cancer
To discover if the adding of a coxib increases the efficacy of the Aromasine.
- Trial name
- NCT00525096
- Testing
- Celecoxib, Exemestane
- Volunteers
- 157 people
- Sponsor
- ARCAGY/ GINECO GROUP
Menopause Syndrome
The Benefits and Risks of Different Menopausal Hormone Replacement Therapy Regimes in the Treatment of Menopause Syndrome
A prospective, open-label, randomized controlled clinical trial to compare the benefits and risks of half-dose or standard-dose conjugated equine estrogens(CEE) plus natural progesterone or dydrogesterone in menopausal hormone…
- Trial name
- NCT03436303
- Testing
- CEE 0.625 mg/MP 100mg, CEE 0.3 mg/MP 100mg, CEE 0.625mg/dydrogesterone
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
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