Clinical trials: Menopause Related Conditions
BRCA Mutation, Estrogen Deficiency
A 3D Bioprinted Hormone-producing Model for BRCA Mutated Patients After Risk Reducing Surgery: the DISC-OVARY Trial
Selecting theca and granulosa cells from removed ovaries of BRCA1/2mut patients undergoing Risk-reducing salpingo-oophorectomy (RRSO) and developing a 3D bioprinted hormone-producing bioprosthetic model.
- Conditions
- BRCA Mutation, Estrogen Deficiency, Surgical Menopause, Menopause Related Conditions
- Trial name
- DISC-OVARY (NCT06497270)
- Testing
- Theca and Granulosa Cell Isolation
- Where
- Italy
- Volunteers
- 3 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Vulvar Atrophy, Vulvovaginal Signs and Symptoms
Retrospective Cohort Study of Symptoms and Quality of Life in Women With Genitourinary Syndrome of Menopause.
The goal of this clinical trial is to retrospectively identify the most prevalent symptoms of genitourinary syndrome of menopause (GSM) among postmenopausal women and to evaluate their impact on quality of life.
- Conditions
- Vulvar Atrophy, Vulvovaginal Signs and Symptoms, Genitourinary Syndrome of Menopause (GSM), Quality of Life
- Trial name
- NCT07737782
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Mucosa Innovations, S.L.
Perimenopause, Cognitive Function in Perimenopause
Cognitive Task Sensitivity in Perimenopause and Nutritional Status
Perimenopause is when you have symptoms of menopause but your periods have not stopped. Brain-related changes are just one of the many symptoms that occur, and changes to memory and concentration ("brain fog") are frequently…
- Trial name
- NCT07648667
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Menopause Related Conditions
Emotional Freedom Technique (EFT) Applied to Postmenopausal Women on Sleep and Quality of Life
The study will be conducted as a randomized controlled experimental study to determine the effects of the Emotional Freedom Technique (EFT) applied to women in menopause on sleep quality and quality of life.
- Trial name
- NCT06578715
- Testing
- Emotional Freedom Technique
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Menopause, Menopause Related Conditions
An Exploratory Investigation of Dietary Supplementation and the Effect on Common Symptoms of Perimenopause and Menopause
A combination of synergistic dietary supplements is hypothesized to significantly improve self-reported measures of menopausal symptoms when compared with a baseline without the intervention.
- Conditions
- Menopause, Menopause Related Conditions, Perimenopausal Disorder
- Trial name
- NCT05617287
- Testing
- Semaine Menopause Supplement
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Semaine Health
Menopause-related Hot Flashes
Finding Links Between Hot flASHes and CardioVascular Disease
The goal of this clinical trial is to learn if neurokinin-1/neurokinin-3 receptor antagonist elinzanetant improves blood vessel health in women with moderate to severe hot flashes.
- Trial name
- FLASH-CV: (NCT07077395)
- Testing
- elinzanetant - reference formulation
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
Menopause Related Conditions
Study of Progesterone in Treatment of Vasomotor Symptoms
The primary objective of the clinical trial is to demonstrate superiority of BHR401 (oral micronized progesterone) versus placebo as a monotherapy for moderate to severe VMS in postmenopausal women.
- Trial name
- PROGEST (NCT03202186)
- Testing
- Progesterone oral capsule
- Where
- Germany
- Volunteers
- 55 people
- Sponsor
- BHR Pharma, LLC
Menopause, Perimenopausal Disorder
A New Hormone Replacement Paradigm: Physiologic Restoration Study
This is a three-year, prospective, observational study looking at the benefits of rhythmically dosed, bio-identical hormones compounded in a carrier cream in 100 symptomatic peri and postmenopausal women.
- Conditions
- Menopause, Perimenopausal Disorder, Menopause Related Conditions
- Trial name
- NCT04190927
- Testing
- Compounded topical estradiol and compounded topical progesterone in a carrier cream
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Women's Hormone Network
Insulin Sensitivity
Association Between Vitamin D and Inflammation and Diabetes Risk in Morbidly Obese Pre-Menopausal Women
Obesity is associated with low-grade inflammation, insulin resistance and low vitamin D status. Vitamin D has traditionally been known to involve in calcium homeostasis and prevent rickets; however, recently it has been…
- Trial name
- VitD2014 (NCT02169050)
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of Illinois at Chicago
Fatigue
Radicle Women's HealthTM: A Study Assessing the Impact of Health and Wellness Products on Fatigue and Related Health Outcomes Among Women Experiencing Menopausal Symptoms
Radicle Women's HealthTM: A randomized, double-blind, placebo- controlled direct-to-consumer study assessing the impact of health and wellness products on fatigue and related health outcomes among women experiencing menopausal…
- Trial name
- NCT07572578
- Testing
- Fatigue Active Product 1
- Where
- United States
- Volunteers
- 502 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Bipolar Disorder, Major Depressive Disorder
Cognitive Behavioral Group Therapy for the Management of Menopause Symptoms in Mood Disorders
The general objective of this study is to advance insight into non-pharmacological treatments for maturing women that impact psychological health and wellbeing of women adapting to menopause, a natural but often challenging…
- Conditions
- Bipolar Disorder, Major Depressive Disorder, Menopause
- Trial name
- Conklin MWW (NCT02860910)
- Testing
- Cognitive Behavioral Group Therapy
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Danette Conklin, PhD