Clinical trials: Menopause Syndrome
Menopause Syndrome, Magnesium
Magnesium-L-Threonate Improves Menopausal Symptoms
This trial has a randomized, single-blind, single-center, parallel-controlled design, with participant screening and trial implementation conducted at Guangdong Provincial People's Hospital.
- Trial name
- NCT06959745
- Testing
- Magnesium-L-Threonate
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial People's Hospital
Polycystic Ovarian Syndrome, Infertility
Menopur® Versus Follistim® in Polycystic Ovarian Syndrome (PCOS)
This multicenter, randomized, open-label exploratory study will be performed in approximately 200 polycystic ovary syndrome (PCOS) but otherwise healthy females undergoing in vitro fertilization (IVF).
- Trial name
- NCT00805935
- Testing
- Menotropin, Progesterone vaginal insert, Follitropin beta
- Where
- 6 sites in United States
- Volunteers
- 110 people
- Sponsor
- Ferring Pharmaceuticals
Premenstrual Syndrome, Premenstrual Dysphoric Disorder
CREST: Samphire Guided Care Program on Wellbeing, Work Productivity, and Quality of Life
This study evaluates the feasibility and efficacy of the Samphire Guided Care (SGC) program a 12-week structured digital health program combining clinician-led onboarding, at-home neuromodulation using the Lutea tDCS device…
- Conditions
- Premenstrual Syndrome, Premenstrual Dysphoric Disorder, Dysmenorrhea, Endometriosis
- Trial name
- CREST (NCT07679074)
- Testing
- Lutea Transcranial Direct Current Stimulation (tDCS) Device, Samphire Guided Care Program
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samphire Group, Inc.
Menopause, Genitourinary Syndrome of Menopause
Examining Effects of Intrarosa in Women With Genitourinary Syndrome of Menopause/Vulvovaginal Atrophy
Tissues of the genitals of women are both androgen (testosterone) and estrogen dependent. The clitoris, vestibule, urethra, anterior vaginal wall, peri-urethral tissue, and pelvic floor all depend on androgens for normal…
- Conditions
- Menopause, Genitourinary Syndrome of Menopause, Vulvovaginal Atrophy, Menopause Syndrome
- Trial name
- NCT03782480
- Testing
- Intrarosa
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Center for Vulvovaginal Disorders
Perimenopause, Perimenopause-Related Depression
Intra Ovarian Muse Cell Injection for Perimenopause Symptom Relief and Ovarian Function Restoration (MUSE-OVARY)
This observational study examines the safety and effects of injecting Muse cells (a type of naturally occurring stem like cells found in adult tissues such as fat or bone marrow) directly into the ovaries of women aged 28 to 70…
- Conditions
- Perimenopause, Perimenopause-Related Depression, Premature Ovarian Insufficiency, Premature Ovarian Failure (POF)
- Trial name
- MUSE-OVARY (NCT07511660)
- Where
- Mexico
- Volunteers
- 12 people
- Sponsor
- Healing Hope International
Genitourinary Syndrome of Menopause (GSM)
A Clinical Study of Chinese Herbal Formula TJAOA103 in Treating Genitourinary Syndrome of Menopause
The goal of this clinical trial is to learn if Chinese herbal formula TJAOA103 works to treat genitourinary syndrome of menopause (GSM). It will also learn about the safety of TJAOA103.
- Trial name
- NCT07160127
- Testing
- TJAOA103
- Where
- China
- Volunteers
- 113 people
- Sponsor
- Tongji Hospital
Allergic Rhinitis, Asthma
Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow
The specific aim of this proposed project is to implement a standard process for integrating MedlinePlus health information prescriptions into the clinic workflow.
- Conditions
- Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy
- Trial name
- NCT00634608
- Testing
- Health Information Prescription
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Menopausal Syndrome
A Randomized, Double-Blind, Parallel, Non-Inferiority, Multicenter Trial Evaluate the Efficacy and Safety of UNCNT Compared to MELSMON in Female With Menopausal Syndrome
The Purpose of this study is to evaluate in a randomized, double-blind, Parallel, Non-inferiority, Multicenter, the efficacy and safety of UNCNT in comparison to the active comparator of MELSMON in female having menopausal…
- Trial name
- UNCNT (NCT01931748)
- Testing
- MELSMON, UNCNT
- Where
- 2 sites in South Korea
- Volunteers
- 104 people
- Sponsor
- Unimed Pharmaceuticals
Vulvovaginal Signs and Symptoms, Genitourinary Syndrome of Menopause
Effects of Ospemifene on Brain Activation Patterns in Women With Sexual Interest-arousal Disorders
Ospemifene is the first oral and non-hormonal treatment for moderate or severe vulvo-vaginal atrophy (VVA) in postmenopausal women who are not candidates to treatment with local oestrogens.
- Conditions
- Vulvovaginal Signs and Symptoms, Genitourinary Syndrome of Menopause, Sexual; Disorder, Arousal, Female
- Trial name
- EROS (NCT04677491)
- Testing
- Ospemifene 60 mg, fMRI experiments
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Hospital Clinic of Barcelona
Breast Cancer, Genitourinary Syndrome of Menopause
Sexual and Vaginal Health in Breast Cancer Women Receiving Aromatase Inhibitors Before and After CO2 Laser Therapy
Background: Vulvovaginal health, directly linked to sexual health, is a key factor for female pleasure. BCS receiving AI are likely to present severe GSM and sexual complaints.
- Trial name
- LIGHT (NCT04619485)
- Testing
- CO2 LASER
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Hospital Clinic of Barcelona
Genitourinary Syndrome of Menopause
Management of Cancer Therapy Related Vulvovaginal Atrophy
The goal of this clinical trial is to: 1. evaluate the efficacy of PRP injection and PRP injection mixed with non-cross-linked hyaluronic acid compared to the control group receiving standard therapy with topical non-cross-linked…
- Trial name
- NCT05782920
- Testing
- Platelet rich plasma, non cross-linked hyaluronic acid, topical HA gel
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Alexandria University
Sleep Apnea, Obesity
Upper Airway of Women With Obstructive Sleep Apnea After Bariatric Surgery
Evaluation of upper airway with Magnetic Resonance and polysomnographic at the pre and post operative of 23 women having undergone bariatric surgery (with the Y-Roux technique) for treatment of obesity.
- Trial name
- NCT05669469
- Testing
- Bariatric surgery
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- Michel Burihan Cahali
Dry Eye
Herbal Medication to Treat Dry Eye in Peri/ Post-menopausal Women
Dry eye disease (DED) in less severe forms are very common, and should ideally be treated outside hospitals, eg., through primary care services and exploiting holistic therapies such as traditional medicine.
- Trial name
- NCT05319041
- Testing
- Wei's Qi Ju Gan Lu Formula
- Where
- Singapore
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Cardiovascular Disease
Milk Consumption and the Metabolic Syndrome in Menopausal Women
Cardiovascular disease (CVD) represents the first cause of mortality in industrialized countries such as Canada and the United States.
- Trial name
- MILK (NCT01163773)
- Testing
- MILK
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Laval University
Genitourinary Syndrome of Menopause
Clinical and Cyto-histological Evaluation of Fractional CO2 Laser Treatment on Genito-Urinary Syndromes of Menopause Related to Vaginal Atrophy
Estrogen deficiency can occur naturally during menopause or as a secondary effect of various treatments for breast or pelvic cancer and can lead to very disabling vulvovaginal symptoms, since it is associated with an anatomical…
- Trial name
- ATROVENANS (NCT05151380)
- Testing
- CO2 laser MonaLisa Touch ®
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Hopital Nord Franche-Comte
Menopause
Clinical Efficacy of Qingxin Zishen Decoction in Treating Menopausal Syndrome and Neuroendocrine Mechanism of Regulating KNDy Neurons
The goal of this clinical trial is to determine the effects of estrogen (Fenmotong) and Qingxin Zishen Decoction on the levels of kisspeptin, NKB, and dynorphin expressed in human KNDy neurons Between patients with menopausal…
- Trial name
- QXZSKNDy (NCT06132620)
- Testing
- Femoston, Qingxin Zishen Decoction
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Yun Chen
Metabolic Syndrome
Female Sex Hormones, Insulin Resistance and Effects of Exercise in a Human Experimental Model of Menopause
The main objective of this study is to investigate the role of female sex hormones in relation to insulin resistance in a controlled human experimental model of menopause and to explore whether exercise and/or hormone treatment…
- Trial name
- NCT02525276
- Testing
- exercise, Hormone treatment
- Volunteers
- 48 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Polycystic Ovary Syndrome, Menopause
Health Risks and Barriers to Management Across the PCOS Lifespan
The overall objective of the proposed pilot project is to explore health literacy and barriers to management of PCOS across the lifespan and determine whether the cardiometabolic risks of PCOS extend beyond menopause.
- Trial name
- HERBS (NCT05769426)
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Genitourinary Syndrome of Menopause
Vaginal CO2 Laser Therapy for Genitourinary Syndrome in Breast Cancer Survivors
This project will be based on three studies over a period on three years. The first study is a dose response study that includes 30 breast cancer survivors.
- Trial name
- NCT06007027
- Testing
- SmartXIDE2V2LR, Monalisa Touch, DEKA, Florence, Italy
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Genitourinary Syndrome of Menopause
Continuous Monitoring and Management of Vaginal Health Via Multifunctional OCT/OCTA/OCE Endoscopy
We have recently developed and optimized a vaginal Optical Coherence tomography/angiography endoscopy imaging system. This technology is able to obtain a comprehensive image of the vaginal epithelium, blood vessels, and lamina…
- Trial name
- NCT04737616
- Testing
- CO2 laser, OCT
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine