Clinical trials: Menorrhagia
Menorrhagia, Dysmenorrhea
Menorrhagia, Dysmenorrhea and Iron Deficiency Among Young Women Soldiers and Effect on Activity
As combat women soldiers are required to more intensive daily activity the investigators believe that the impact of menorrhagia, dysmenorrhea and its clinical consequence (as characterized by, anemia iron deficiency and reduced…
- Conditions
- Menorrhagia, Dysmenorrhea, Iron Deficiency Anemia
- Trial name
- NCT02685501
- Testing
- no intervention
- Where
- 2 sites in Israel
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Menorrhagia Due to Benign Causes
A Single Arm Clinical Study of the Safety and Efficacy of the AURORA™ Endometrial Ablation System
This is a clinical study without a formal hypothesis. The primary objective of the study is to evaluate the use of the Aurora Endometrial Ablation System in achieving a return to normal menstrual blood loss at 12 months…
- Trial name
- NCT02023801
- Testing
- Aurora Endometrial Ablation System
- Where
- Mexico
- Volunteers
- 24 people
- Sponsor
- Minerva Surgical, Inc.
Menstrual Bleeding, Heavy
NovaSure Study: Endometrial Ablation in Women With Heavy Menstrual Bleeding
Heavy menstrual bleeding (HMB) affects 30% of women worldwide. It negatively influences physical activity, work productivity, sexual life and overall quality of life.
- Trial name
- RAMBOS (NCT05856838)
- Testing
- NovaSure ablation
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Ghent
Von Willebrand Diseases
A Pilot Crossover Trial of Prophylactic Wilate Compared to Placebo for Heavy Menstrual Bleeding in Patients With VWD
The EMPOWER trial is a pilot multi-center, placebo-controlled (normal saline), double-blind (patient and outcome assessor), crossover, 2-year randomized trial in female outpatients with von Willebrand disease (VWD) and heavy…
- Trial name
- EMPOWER (NCT06205095)
- Testing
- Lyophilized concentrate of human coagulation von Willebrand Factor and factor VIII
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- Unity Health Toronto
Aplastic Anemia, Menorrhagia
Treatment of Menorrhagia in Women With Thrombocytopenia Using Platelets or Platelets and Hormones
This study will explore the role of oral contraceptive pills in managing uterine bleeding in women who have low blood platelet counts as a result of aplastic anemia.
- Conditions
- Aplastic Anemia, Menorrhagia, Amenorrhea
- Trial name
- NCT00556400
- Testing
- Lo-Ovral Oral Contraceptive Pills
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Menorrhagia
Sonography Guided Transcervical Ablation of Uterine Fibroids
The objective of this study is to establish the safety and effectiveness of the Sonata® System in the treatment of symptomatic uterine fibroids.
- Trial name
- SONATA (NCT02228174)
- Testing
- Intrauterine Ultrasound-Guided Radiofreq. Ablation System
- Where
- 23 sites in United States, Mexico
- Volunteers
- 147 people
- Sponsor
- Gynesonics
Uterine Leiomyoma
Directed Ablation of Uterine Fibroids Using a Noninvasive Approach
The purpose of this clinical study is to assess the safety and effectiveness of the Mirabilis System for treating uterine fibroids in women who are seeking relief from fibroid-related abnormal uterine bleeding but want to avoid…
- Trial name
- DIANA (NCT03219385)
- Testing
- Mirabilis System
- Volunteers
- 180 people
- Sponsor
- Mirabilis Medica, Inc.
Menorrhagia, Uterine Fibroids
to Evaluate the Efficacy and Safety of KLH-2109 in Patients With Uterine Fibroids and Menorrhagia
The goal of this clinical trial was to determine whether the investigational drug KLH-2109 is effective for treating excessive menstrual bleeding in patients with uterine fibroids.
- Trial name
- NCT07378098
- Where
- South Korea
- Volunteers
- 254 people
- Sponsor
- JW Pharmaceutical
Menorrhagia, Uterine Bleeding
Surgical Treatments Outcomes Project for Dysfunctional Uterine Bleeding (STOP-DUB)
STOP-DUB is a multicenter randomized clinical trial that is assessing the efficacy and effectiveness of hysterectomy versus endometrial ablation (EA) for dysfunctional uterine bleeding (DUB) in women for whom medical management…
- Trial name
- NCT00114088
- Testing
- hysterectomy, endometrial ablation
- Volunteers
- 242 people
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Women With Coagulation Disorders
Effect of Ginger on Heavy Menstrual Bleeding in Women With Coagulation Disorders
The GINGER-BLEED study is a randomized, double-blind, placebo-controlled clinical trial evaluating the effect of ginger powder on heavy menstrual bleeding in women with coagulopathies.
- Trial name
- GINGER-BLEED (NCT07595640)
- Testing
- Ginger
- Volunteers
- 74 people
- Sponsor
- University of Valladolid
Idiopathic Menorrhagia
MiCo - Mirena or Conventional Medical Treatment for Menorrhagia
The aim of this prospective, non-interventional post-marketing surveillance study is to obtain data on safety and efficacy of Mirena in treatment of heavy menstrual bleeding (Menorrhagia) under daily-life treatment conditions.For…
- Trial name
- NCT01085487
- Testing
- Levonorgestrel (Mirena, BAY86-5028), Hormonal treatment, Antifibrinolytic treatment
- Where
- 14 sites in Albania, Bosnia and Herzegovina and 12 more
- Volunteers
- 1,211 people
- Sponsor
- Bayer
Heavy Menstrual Bleeding, Bleeding Disorder
Heavy Menstrual Bleeding Progestin Treatment in Bleeding Disorders Study
The goal of this multicenter prospective observational study and registry of U.S. adolescents and young adults with heritable bleeding disorders is to determine the bleeding outcomes, satisfaction, hemostatic parameter changes…
- Conditions
- Heavy Menstrual Bleeding, Bleeding Disorder, Von Willebrand Diseases
- Trial name
- HMB-BD (NCT05916469)
- Testing
- Levonorgestrel Intrauterine System, Norethindrone Acetate
- Where
- 9 sites in United States
- Volunteers
- 300 people
- Sponsor
- Oregon Health and Science University
Heavy Menstrual Bleeding
Transcutaneous Auricular Neurostimulation as a Treatment for Women With Heavy Menstrual Bleeding: A Dose-finding Trial
This study is designed as an open label, single-arm, decentralized research study in which patients with idiopathic heavy menstrual bleeding will receive transcutaneous auricular neurostimulation (tAN), which targets the…
- Trial name
- NCT06814028
- Testing
- Volta System
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Spark Biomedical, Inc.
Menorrhagia
Oral Tranexamic Acid Versus Diosmin for Treatment of Menorrhagia in Women Using Copper IUD
To compare the efficacy of tranexamic acid and diosmin in reducing menstrual blood loss in women having Intra Uterine Contraceptive Device (IUD) and suffer from menorrhagia.
- Trial name
- NCT02616731
- Testing
- Tranexamic Acid, Diosmin
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Uterine Fibroids, Menorrhagia, Endometriosis
Study Comparing Conventional vs. Robotic-assisted Laparoscopic Hysterectomy
The purpose of this study is to compare two ways of performing laparoscopic hysterectomy - robotic-assisted vs. conventional laparoscopy.
- Trial name
- NCT00485355
- Testing
- conventional laparoscopic hysterectomy, robotic assisted laparoscopic hysterectomy
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Menorrhagia, Heavy Menstrual Bleeding
Efficacy and Safety Study of XP12B in Women With Menorrhagia
The purpose of this study is to determine whether XP12B is effective and safe in the treatment of women with heavy menstrual bleeding associated with menorrhagia.
- Trial name
- NCT00386308
- Testing
- Tranexamic acid tablets
- Where
- 52 sites in United States
- Volunteers
- 196 people
- Sponsor
- Ferring Pharmaceuticals
Heavy Menstrual Bleeding
Tranexamic Acid in Adolescents With Heavy Menstrual Bleeding
This is a study to learn more about a drug called Tranexamic acid (TA), otherwise known as Lysteda, and whether or not this drug can decrease menstrual blood loss in young women and lead to an increase in the quality of life.
- Trial name
- NCT01846507
- Testing
- Tranexamic Acid
- Where
- 5 sites in United States
- Volunteers
- 32 people
- Sponsor
- Nationwide Children's Hospital
Uterine Fibroids, Menorrhagia
Uterine Artery Embolization for Symptomatic Fibroids
This study will evaluate the safety, efficacy , quality of life and patient satisfaction of uterine artery embolization for the treatment of symptomatic uterine fibroids.
- Conditions
- Uterine Fibroids, Menorrhagia, Adenomyosis
- Trial name
- NCT00354471
- Testing
- Uterine Artery Embolization
- Where
- Canada
- Sponsor
- University of Manitoba
Menorrhagia Due to Benign Causes
A Two-Phase Clinical Study of the Minerva AURORA Ablation System
The primary objective of this study is to evaluate the use of the Aurora Ablation System in reducing menstrual blood loss at 12 months post-treatment.
- Trial name
- NCT02035332
- Testing
- Aurora Endometrial Ablation System
- Where
- 3 sites in Hungary
- Volunteers
- 23 people
- Sponsor
- Minerva Surgical, Inc.
Arterial Hypertension, Postmenopausal; Menorrhagia
Effects of Resistance Training Intensity on Cardiovascular Parameters of Hypertensive Women
The goal of this clinical trial is to understand about the effects of resistance training (RT) intensity on cardiovascular parameters in postmenopausal women with systemic arterial hypertension (SAH).
- Conditions
- Arterial Hypertension, Postmenopausal; Menorrhagia, Cardiovascular Diseases
- Trial name
- NCT06538454
- Testing
- Resistance training
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- University of Sao Paulo