Clinical trials: Menstrual Bleeding, Heavy
Polycystic Ovary Syndrome (PCOS), Myo-inositol
Myo-Inositol and D-Chiro-Inositol for Menstrual Irregularities and Hormone Changes in Women With Polycystic Ovarian Syndrome
The goal of this clinical trial is to determine whether a combination of myo-inositol (MI) and D-chiro-inositol (DCI) with folic acid is more effective than placebo (Folic acid alone) in improving menstrual irregularities and…
- Conditions
- Polycystic Ovary Syndrome (PCOS), Myo-inositol, D-chiro-inositol
- Trial name
- NCT07701525
- Testing
- Myo-Inositol and D-Chiro-Inositol Combination Therapy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Nishtar Medical University
Assessing the Bleeding Profile and the Quality of Life of the Enrolled Patients Before and 1 Year After Drug Intervention
Use of Recombinant Factor VII as a Prophylactic Therapy for Adolescent Females With Heavy Menstrual Bleeding
the study is conducted on adolescent females proved to be Glanzmanns Thrombaesthenia with heavy menstrual bleeding by the use of 3 doses of recombinant factor VII in the first day of their cycles.
- Trial name
- NCT06258980
- Testing
- Proph7
- Where
- Egypt
- Volunteers
- 3 people
- Sponsor
- Minia University Hospital
Menorrhagia, Abnormal Uterine Bleeding
Efficacy of Calcium Dobesilate Versus Tranexamic Acid for Treating Heavy Menstrual Bleeding
The goal of this clinical trial is to determine if calcium dobesilate is an effective alternative to tranexamic acid for treating menorrhagia in women aged 18 to 39 years.
- Trial name
- NCT06763094
- Testing
- Calcium dobesilate (Doxium), Tranexamic Acid
- Volunteers
- 100 people
- Sponsor
- University of Health Sciences Lahore
Menstrual Bleeding, Heavy
Evaluation of the Contraceptive Efficacy
Combined oral contraceptives are not the preparation of first choice in breastfeeding women as they may influence the quality and quantity of breast milk.
- Trial name
- NCT06689150
- Testing
- Drospinetta
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Menorrhagia
A Study Run at Multiple Study Sites to Test Whether the SAMANTA Questionnaire That is Used to Diagnose Heavy Menstrual Bleeding (HMB), Can Also be Used to Assess Changes of Severity of HMB in Women With HMB Who Are Treated During 12 Months With a Chronic Hormonal Treatment
A study run at multiple study sites in Spain to test whether the SAMANTA questionnaire that is used to diagnose heavy menstrual bleeding (HMB), can also be used to assess changes of severity of HMB in women with HMB who are…
- Trial name
- SAMIRA (NCT03751800)
- Testing
- Chronic hormonal treatment
- Where
- Spain
- Volunteers
- 422 people
- Sponsor
- Bayer
Menorrhagia
Safety & Effectiveness Study of AEGEA Vapor System to Treat Excessive Uterine Bleeding
The purpose of this study is to determine if the AEGEA Vapor System for endometrial ablation is safe and effective for reducing menstrual blood loss in women with excessive uterine bleeding (menorrhagia)
- Trial name
- NCT01979861
- Testing
- AEGEA Vapor System(TM)
- Where
- 15 sites in United States, Canada and 2 more
- Volunteers
- 230 people
- Sponsor
- Aegea Medical, Inc.
Heavy Menstrual Bleeding
Dexamethasone for Excessive Menstruation
This study builds on previous research which has provided compelling evidence that deficient activity of glucocorticoids in the endometrium is a cause of increased menstrual bleeding.
- Trial name
- dexFEM (NCT01769820)
- Testing
- Dexamethasone
- Where
- United Kingdom
- Volunteers
- 123 people
- Sponsor
- University of Edinburgh
Menorrhagia, Heavy Menstrual Bleeding
Safety Study of XP12B in Women With Menorrhagia
The purpose of this study is to evaluate the safety of XP12B in women with heavy menstrual bleeding associated with menorrhagia.
- Trial name
- NCT00113568
- Testing
- Tranexamic acid tablets (XP12B)
- Where
- 59 sites in United States
- Volunteers
- 784 people
- Sponsor
- Ferring Pharmaceuticals
Von Willebrand Factor Deficiency
Low VW Activity in Adolescent HMB
This is a research study for patients diagnosed with heavy menstrual bleeding (HMB) and low Von Willebrand Factor (VWF). Menstruation, also known as a period, is the regular discharge of blood and tissues from the uterus.
- Trial name
- Low VWF (NCT02933411)
- Testing
- Genetic Analysis, Medical Record Data Abstraction, Pictorial Blood Assessment Chart (PBAC) score
- Where
- 12 sites in United States
- Volunteers
- 120 people
- Sponsor
- Baylor College of Medicine
Menorrhagia, Endometrial Neoplasms
Evaluation of the Goldstein SonoBiopsy™ Catheter for Diagnosing Endometrial Pathology
To assess the adequacy of an endometrial biopsy sample obtained using sonohysterography.
- Conditions
- Menorrhagia, Endometrial Neoplasms, Polycystic Ovary Syndrome, Uterine Neoplasms
- Trial name
- NCT01969396
- Testing
- SonoBiopsy Catheter, Endometrial biopsy catheter
- Where
- Panama
- Volunteers
- 2 people
- Sponsor
- Cook Group Incorporated
Laparoscopic Myomectomy
A Retrospective Review Of Outcomes Following Laparoscopic Myomectomy
This will be a retrospective review of approximately 900 patients who have undergone laparoscopic myomectomy since 1999. patients will be contacted by phone and surveyed.
- Trial name
- retromyo (NCT00672750)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- The Advanced Gynecologic Surgery Institute
Menorrhagia, Heavy Menstrual Bleeding
Efficacy and Safety Study of XP12B in Women With Menorrhagia
The purpose of this study is to determine whether XP12B is effective and safe in the treatment of women with heavy menstrual bleeding associated with menorrhagia.
- Trial name
- NCT00386308
- Testing
- Tranexamic acid tablets
- Where
- 52 sites in United States
- Volunteers
- 196 people
- Sponsor
- Ferring Pharmaceuticals
Contraception, Menorrhagia
Bleeding Pattern and User Satisfaction During Second Consecutive MIRENA® in Contraception and Treatment of Menorrhagia
The purpose of this study is to assess the bleeding pattern during the last 3 months of the first MIRENA® and the first year of the second MIRENA® use.
- Trial name
- NCT00393198
- Testing
- Levonorgestrel (Mirena, BAY86-5028), Cytotec
- Where
- 17 sites in Finland, France and 2 more
- Volunteers
- 204 people
- Sponsor
- Bayer
Adenomyosis
Norwegian Adenomyosis Study II: Gene Expression Profiling of Adenomyosis
Adenomyosis is characterized by the appearance of endometrial cells in the muscular layer of the uterus. It affects about 15-20% of the female population.
- Trial name
- NAPPED II (NCT02197923)
- Testing
- Myometrial biopsy, endometrial biopsy
- Where
- Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Menorrhagia
A Clinical Study of the Aqua Therapeutics Thermal Therapy Vapor Ablation System in Premenopausal Women With Abnormal Uterine Bleeding
Abnormal uterine bleeding (AUB) is defined as "flow outside of normal volume, duration, regularity, or frequency". Acute AUB is excessive bleeding that requires immediate intervention to prevent further blood loss.
- Trial name
- AQTH-EA-PIV-24 (NCT07877051)
- Testing
- Aqua Therapeutics Thermal Therapy Vapor Ablation System (ATTTVAS)
- Where
- 3 sites in Georgia
- Volunteers
- 43 people
- Sponsor
- Aqua Therapeutics, Inc.
Menorrhagia
Registry Study of Genesys HTA for Treatment of Menorrhagia
This is a clinical registry of an FDA approved device system called the Genesys Hydro ThermAblatorTM (HTA) system (Boston Scientific).
- Trial name
- Genesys HTA (NCT01197547)
- Testing
- Genesys HTA
- Where
- 19 sites in United States
- Volunteers
- 1,014 people
- Sponsor
- Minerva Surgical, Inc.
Leiomyoma, Uterine Fibroids
Safety and Effectiveness Study of RF Ablation of Uterine Fibroids to Reduce Menstrual Bleeding: the Fibroid Ablation Study
The primary objective of this study is to test the hypothesis that a minimum 75% volume radiofrequency ablation of fibroids associated with menorrhagia results in reduction of menstrual bleeding.
- Conditions
- Leiomyoma, Uterine Fibroids, Menorrhagia
- Trial name
- FAST (NCT00768742)
- Testing
- VizAblate Intrauterine Ultrasound-Guided RF Ablation
- Where
- 3 sites in Canada
- Sponsor
- Gynesonics
Menorrhagia
Study of a Levonorgestrel 52 mg Intrauterine System for the Treatment of Heavy Menstrual Bleeding
To assess the efficacy of a levonorgestrel 52 mg intrauterine system as a treatment for heavy menstrual bleeding.
- Trial name
- NCT03642210
- Testing
- Levonorgestrel 52 mg intrauterine system
- Where
- 29 sites in United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Medicines360
Menorrhagia
Prevalence and Impact on Quality of Life, Academic Performance, and Blood Indices of Heavy Menstrual Bleeding Among Female Students in Assiut University, Egypt
The cause of menstrual disorders is unknown because many female students, embarrassed or unsure of what is "normal," never seek care.
- Trial name
- menorrhagia (NCT07188259)
- Where
- Egypt
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hemophilia, Menstrual Flow Excessive
Extended Half Life Factor (EHF) Products For Heavy Menstrual Bleeding in Hemophilia Carriers
The purpose of this feasibility study is to find out if two clotting factor products, Eloctate [hemophilia A] and Alprolix [hemophilia B], can reduce the amount of menstrual bleeding in female hemophilia A and B carriers (14…
- Trial name
- NCT03272568
- Testing
- Recombinant FVIII Fc fusion product Eloctate, Recombinant FIX Fc fusion product Alprolix, Patient-operated diagnostic device for anemia AnemoCheck.
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Emory University