Clinical trials: Menstrual Cycle
Extracellular Vesicles
Isolation and Characterization of the Extracellular Vesicles Secreted by the Human Endometrium
The main aim of this study is to describe the morphology, size distributions and specific markers of the different vesicles populations present in the human endometrial fluid.
- Trial name
- NCT02797834
- Testing
- Endometrial fluid collection
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Igenomix
Menstrual Cycles
Period Tracker Lay User Study
This study will assess the ability of the lay user to obtain and record a result. Comprehension of the instructions for use of the product will also be assessed.
- Trial name
- NCT05091658
- Testing
- LH Urine Test
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- SPD Development Company Limited
Cyclic Mastodynia, Premenstrual Syndrome
Dose-dependent Effects of VAC BNO 1095 on Cyclic Mastodynia and Premenstrual Syndrome
Prospective, double-blind, placebo-controlled, 3 parallel groups, multi-center study in 180 patients with cyclic mastodynia with premenstrual syndrome.
- Trial name
- NCT01309113
- Testing
- VAC BNO 1095 film coated tablets
- Where
- Czechia
- Volunteers
- 191 people
- Sponsor
- Bionorica SE
Premenstrual Syndrome, Mastodynia
Efficacy and Safety of 20 mg (2 Tablets of 10mg)VAC BNO 1095 FCT on Cyclic Mastodynia and PMS
The purpose of this study is to proof the efficacy and safety of 20 mg (2 tablets of 10 mg) VAC BNO 1095 film-coated tablets in patients suffering from cyclic mastodynia and PMS (pre menstrual syndrome).
- Trial name
- NCT01870687
- Testing
- 20mg VAC BNO 1095 FCT
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Bionorica SE
Polycystic Ovarian Syndrome
Analysis of Two Therapeutic With Cetrotide® in Polycystic Ovarian (PCO) Women in Assisted Reproductive Technology (ART)
This is a randomized open-label study to compare between in-vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) outcomes of the two regimen of Cetrotide® (Cetrorelix acetate) which are 0.25 milligram (mg) used from…
- Trial name
- ATTAC-PCO (NCT01185704)
- Testing
- Cetrorelix acetate, Recombinant Human Choriogonadotropin (r-hCG), Recombinant human follicle stimulating hormone (r-hFSH)
- Where
- France
- Volunteers
- 136 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Sexual Dysfunction, Physiological
Effect Of Menstrual Cycle On Vaginal Blood Flow In Pre-Menopausal Healthy Women.
The Pfizer developed Heat Wash-Out (HWO) system is a software controlled electromechanical system designed to measure vaginal wall blood flow. A small vaginal probe is attached to a control unit. Output data is collected on a PC.
- Trial name
- HWO VBF (NCT00443027)
- Testing
- Vaginal Heat Wash-Out Device
- Where
- 2 sites in Australia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Heavy Menstrual Bleeding
Delivering tAN to Reduce HMB: The LUNA Study
The LUNA study is a prospective, randomized, double-blind, sham-controlled, decentralized clinical trial in participants with heavy menstrual bleeding of no known structural cause.
- Trial name
- LUNA (NCT07326722)
- Testing
- Sparrow Link
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Spark Biomedical, Inc.
Uterine Fibroids, Leiomyoma
An Open-Label Study to Evaluate the Effect of Elix Cycle Balance & Elix Daily Harmony on Fibroid-related Symptoms
This is a 24-week, single-arm, open-label, virtual study evaluating the effects of Elix Cycle Balance and Elix Daily Harmony on uterine fibroid-related symptoms and quality of life in 42 participants.
- Conditions
- Uterine Fibroids, Leiomyoma, Menstrual Pain
- Trial name
- NCT07078682
- Testing
- Elix Daily Harmony
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Zenchi, Inc.
Menstrual Cycle Disorder, Menstrual Symptoms
Evaluation of The Cycle SyncingⓇ Method: A 12-Week Virtual Clinical Trial
This 12-week, 100% virtual single-group open-label trial evaluates the Cycle SyncingⓇ Method using the MyFLO app, MIRA hormonal monitoring, and continuous glucose monitoring to assess reduction in menstrual cycle symptom burden…
- Conditions
- Menstrual Cycle Disorder, Menstrual Symptoms, Hormonal Imbalance
- Trial name
- NCT07286136
- Testing
- MyFLO App
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- FLO LIVING, LLC
Fertility
Physiological Data in the Menstrual Cycle
Research results suggest changes of physiological parameters such as heart rate, respiration, skin conductance response, sleep duration, sleep quality and skin perfusion during the menstrual cycle.
- Trial name
- PDMC (NCT03128983)
- Testing
- Participants wear a sensor bracelet for collecting physiological data and conducted urine tests to estimate the day of ovulation
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Ava AG
Premenstrual Syndrome
Study Evaluating Levonorgestrel/Ethinyl Estradiol (LNG/EE) in PMS
The purpose of this study is to determine whether LNG/EE is effective in the treatment of menstrual cycle related symptoms.
- Trial name
- NCT00161681
- Testing
- Levonorgestrel/Ethinyl Estradiol
- Where
- 48 sites in United States
- Volunteers
- 200 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Menstruation Disorders
Partial Double-Blind, Placebo-Controlled Study to Assess the Effect of Anastrozole on the Endometrium in Healthy Volunteers
Aromatase inhibitors have been approved for use in postmenopausal women to treat and prevent breast cancer. They act by blocking the action of the enzyme, aromatase, that is necessary for the production of estradiol.
- Trial name
- NCT00467493
- Testing
- Anastrozole
- Where
- 2 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Meditrina Pharmaceuticals
Menstrual Cycles
Menstrual Cycle Symptom Tracking
This study will provide menstrual cycle symptom information from women over the course of three menstrual cycles to determine whether there are any noticeable physiological changes that can be related to stage of the menstrual…
- Trial name
- NCT04756739
- Testing
- Clearblue Connected Ovulation Test System
- Where
- United Kingdom
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- SPD Development Company Limited
PMS, Menstrual Discomfort
An Investigation of Premama Balance and Its Effects on Hormonal Imbalances
An investigation of the dietary supplement marketed as "Premama Balance" on markers of subjective wellbeing in trial participants such as common symptoms of PMS and menstrual symptoms, as well as its effects on aiding in…
- Conditions
- PMS, Menstrual Discomfort, Hormone Disturbance, Menstrual Pain
- Trial name
- NCT05518006
- Testing
- PreMama Balance
- Volunteers
- healthy volunteers welcome
- Sponsor
- Premama Inc.
Irregular Menstrual Cycle
Duphaston in Cycle Regularization: A Post-marketing, Prospective, Multicenter, Observational Study
In India Duphaston is approved and widely used for the treatment of progesterone deficiencies such as for management of dysmenorrhea, endometriosis, secondary amenorrhea, irregular cycles, dysfunctional uterine bleeding…
- Trial name
- NCT01525563
- Where
- 32 sites in India
- Volunteers
- 1,000 people
- Sponsor
- Abbott
Metrorrhagia
Study of a 4-phasic Oral Contraceptive for the Treatment of Heavy Menstrual Bleeding
To evaluate efficacy and safety of a combined oral contraceptive of estradiol valerate and dienogest in the treatment of heavy menstrual bleeding
- Trial name
- NCT01638923
- Testing
- EV/DNG (Qlaira, Natazia, BAY86-5027)
- Where
- 41 sites in China, Philippines and 4 more
- Volunteers
- 339 people
- Sponsor
- Bayer
Menstrual Cycle, Ovulation
Apple Women's Health Study
This is an observational longitudinal study to advance the understanding of menstrual cycle and gynecologic health conditions including PCOS, infertility and breast cancer.The study will be hosted within the Research…
- Conditions
- Menstrual Cycle, Ovulation, Menstruation, Polycystic Ovary Syndrome
- Trial name
- NCT04196595
- Where
- United States
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Apple Inc.
Premenstrual Syndrome, Menstrual Discomfort
A Clinical Trial to Evaluate the Effects of the Kaia Relief - Cycle System on Premenstrual Symptom Severity, Menstrual Discomfort, and Overall Well-Being in Premenopausal Women.
This is a single-group, open-label, decentralized clinical trial evaluating the effects of the Kaia Relief - Cycle System (a commercial dietary supplement consisting of Day and Night capsules) on premenstrual symptom severity…
- Conditions
- Premenstrual Syndrome, Menstrual Discomfort, Premenstrual Symptoms
- Trial name
- NCT07876050
- Testing
- Kaia Relief - Cycle System (Day and Night)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Vivance Group
Dysmenorrhea
Safety Study of Ethinylestradiol/Drospirenone in Dysmenorrhea
The purpose of this study is to investigate efficacy of ethinylestradiol for intracyclic bleeding profile in patients with dysmenorrhea and to investigate the long term safety
- Trial name
- NCT00461305
- Testing
- DRSP 3 mg/EE 20 µg (13 cycles), DRSP 3 mg/EE 30 µg (6 cycles)
- Where
- 26 sites in Japan
- Volunteers
- 420 people
- Sponsor
- Bayer
Cyclic Breast Pain, Cyclic Mastalgia
Study of Afimoxifene Gel to Treat Cyclic Mastalgia in Premenopausal Women
The purpose of this study is to evaluate the efficacy of two doses of 4-hydroxy tamoxifen (4-OHT) compared with placebo on the intensity of cyclic mastalgia in pre-menopausal women with regular menstrual cycles who are not taking…
- Trial name
- NCT00272714
- Testing
- Afimoxifene (0.057%) in hydroalcoholic gel
- Volunteers
- 146 people
- Sponsor
- ASCEND Therapeutics