Clinical trials: Menstrual Cycle Phase
PMDD, Premenstrual Dysphoric Disorder (PMDD)
Identification and Validation of Epigenetic Biomarkers of PMDD
This research is being done to examine epigenetic markers and mood changes across the menstrual cycle, particularly in premenstrual dysphoric disorder (PMDD).
- Conditions
- PMDD, Premenstrual Dysphoric Disorder (PMDD), Premenstrual Syndrome-PMS, Premenstrual Syndrome
- Trial name
- BIO (NCT06771583)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Metrorrhagia
Study of a 4-phasic Oral Contraceptive for the Treatment of Heavy Menstrual Bleeding
To evaluate efficacy and safety of a combined oral contraceptive of estradiol valerate and dienogest in the treatment of heavy menstrual bleeding
- Trial name
- NCT01638923
- Testing
- EV/DNG (Qlaira, Natazia, BAY86-5027)
- Where
- 41 sites in China, Philippines and 4 more
- Volunteers
- 339 people
- Sponsor
- Bayer
Sleep-Disordered Breathing
HighCycle Study: Effect of High Altitude on Sleep Disordered Breathing in Women Related to Their Menstrual Cycle Phase
Prospective cohort study investigating the menstrual cycle phase (MCP) dependent sleep disordered breathing (SDB) in women travelling to 3600 m.
- Trial name
- NCT06498544
- Testing
- Exposure to 3600 m
- Where
- Kyrgyzstan
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Contraceptives, Oral, Sex Hormone
Oral Contraceptive vs Menstrual Cycle Ex Vivo Model
Despite comprising half the population, females are often left out of muscle research due to the impact of changing hormones during the menstrual cycle and when using oral contraceptives.
- Trial name
- OCEV (NCT06124274)
- Testing
- Protein tracer drink
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Menstruation Disturbances, Luteal Phase Defect
Energy Restriction and Hormones in Premenopausal Women
A growing body of epidemiological and biological evidence strongly suggests that physical activity may reduce the risk of breast cancer.
- Trial name
- NCT05107804
- Testing
- Exercise+CR, Light Conditioning
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Penn State University
Contraception, Estrogen Deficiency
Effect of Oestrogen on Musculoskeletal Outcomes
This cross-sectional comparison and prospective cohort design study will investigate differences in calcium metabolism, biochemical markers of bone and reproductive health, musculoskeletal health, and iron status between women…
- Conditions
- Contraception, Estrogen Deficiency, Estrogen Excess
- Trial name
- E2 (NCT05587920)
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Army Health Branch, British Army
Menstrual Cycle, Luteal Phase Progesterone Levels
Corpus Luteum Function and Cardiovascular Adaptation in a Natural MOCK Cycle.
In infertility treatment, embryos are created in vitro after eggs have been fertilised by sperm using in vitro fertilisation or intracytoplasmic sperm injection techniques.
- Conditions
- Menstrual Cycle, Luteal Phase Progesterone Levels, Luteal Phase Adaptation, MOCK Cycle
- Trial name
- CLEAR (NCT07648381)
- Testing
- Blood samples for the analysis of biomarkers., Transvaginal ultrasound for follicle and endometrium measurements., Mean Arterial Pressure measurement.
- Where
- Belgium
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
American Society of Anesthesiologists (ASA) I-II Risk Groups, the Follicular (Days 1-12 From Last Menstruation) or Luteal (Days 20-24) Phase of the Menstrual Cycle
Menstrual Cycle Phase and Virtual Reality on Preoperative Anxiety
This study aims to examine the effects of menstrual cycle phase and a virtual reality (VR) intervention on preoperative anxiety in female patients scheduled for septorhinoplasty surgery.
- Conditions
- American Society of Anesthesiologists (ASA) I-II Risk Groups, the Follicular (Days 1-12 From Last Menstruation) or Luteal (Days 20-24) Phase of the Menstrual Cycle, Aged 18-55
- Trial name
- NCT07337941
- Testing
- 15-minute video providing a visual and auditory experience (Training Video), State-Trait Anxiety Inventory (STAI I-II), The decision for a 15-minute preoperative observation without visual and auditory experience depends on the phase of the menstrual cycle and group assignment.
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Polycystic Ovarian Syndrome
Analysis of Two Therapeutic With Cetrotide® in Polycystic Ovarian (PCO) Women in Assisted Reproductive Technology (ART)
This is a randomized open-label study to compare between in-vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) outcomes of the two regimen of Cetrotide® (Cetrorelix acetate) which are 0.25 milligram (mg) used from…
- Trial name
- ATTAC-PCO (NCT01185704)
- Testing
- Cetrorelix acetate, Recombinant Human Choriogonadotropin (r-hCG), Recombinant human follicle stimulating hormone (r-hFSH)
- Where
- France
- Volunteers
- 136 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Premenstrual Syndrome
Study Evaluating Levonorgestrel/Ethinyl Estradiol (LNG/EE) in PMS
The purpose of this study is to determine whether LNG/EE is effective in the treatment of menstrual cycle related symptoms.
- Trial name
- NCT00161681
- Testing
- Levonorgestrel/Ethinyl Estradiol
- Where
- 48 sites in United States
- Volunteers
- 200 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Menstrual Cycle Phase, Athletic Performance
Balance Training To Enhance Stability And Athletic Performance During The Menstrual Cycle
This study was done to investigate the effect of balance training on improving balance and athletic performance during menstrual cycle in young athletic females Does balance training improve balance and athletic performance…
- Conditions
- Menstrual Cycle Phase, Athletic Performance, Balance Training
- Trial name
- NCT06842212
- Testing
- Balance Training
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- British University In Egypt
Circadian Rhythm, Menstrual Cycle Phase
Investigating the Effects of Time-of-day and Menstrual Cycle Phase (Low and High Progesterone) on Female's Cognitive and Strength Performance
This study is designed to determine whether time-of-day and menstrual cycle phase influence athletic performance and is expected to contribute valuable insight into how both time-of-day, and hormonal factors can influence…
- Conditions
- Circadian Rhythm, Menstrual Cycle Phase, Female Athletes, Executive Function (Cognition)
- Trial name
- NCT07399847
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lancaster University
Type 1 Diabetes Mellitus
MEnstrual Cycle pHase ANd dIabeteS Management
This study evaluates the impact of menstrual cycle phases on insulin sensitivity, glycaemic control, and insulin requirements in women with type 1 diabetes (T1D).
- Trial name
- MECHANISM (NCT07004504)
- Where
- Switzerland
- Volunteers
- 77 people
- Sponsor
- DCB Research AG
Fat Metabolism
Fatmax Exercise in Menstrual Phases: Effects on Fat Metabolism & Body Composition in NWO Women
Effects of a Fatmax exercise intervention during different menstrual phases on fat metabolism and body composition in NWO women
- Trial name
- NCT06961734
- Testing
- follicular group, luteal group, Control group
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
Muscle Protein Synthesis
The Effect of Menstrual Cycle Phase and Protein Dose on Muscle Protein Synthesis
Adaptation to resistance exercise requires maximal rates of muscle protein synthesis, which can be achieved with post-exercise ingestion of ~20g of protein.
- Trial name
- NCT05178732
- Testing
- Dose of protein, Menstrual cycle phase
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Fertility Disorders, Fertility Issues
Menstrual Phase Endometrial Scratch in IUI Cycles
Patients undergoing treatment with intrauterine insemination (IUI) will be randomized to receive an endometrial scratch or sham procedure during the menstrual phase of the treatment cycle.
- Trial name
- NCT04641598
- Testing
- Endometrial Scratch
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Functional Hypothalamic Amenorrhea, FHA
A Study to Investigate Mibavademab in Adult Women With Functional Hypothalamic Amenorrhea
This study is researching an experimental drug called mibavademab (also called "study drug"). The study is focused on participants with a condition called Functional Hypothalamic Amenorrhea (FHA).
- Trial name
- KYRIAD (NCT07235917)
- Testing
- Mibavademab
- Where
- 11 sites in United States
- Volunteers
- 34 people
- Sponsor
- Regeneron Pharmaceuticals
Ovarian Cysts, Menstrual Cycle
Timing of LNG-IUD Insertion and Ovarian Cyst Formation
In this prospective observational study, the effect of timing of insertion (early/late follicular; early/late luteal) on ovarian cyst development in women receiving an LNG-IUD will be assessed ultrasonographically at months 0, 3…
- Conditions
- Ovarian Cysts, Menstrual Cycle, Intrauterine Device (IUD)
- Trial name
- LNG-IUD TIMING (NCT07248553)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Menstrual Cycle, Optic Nerve Sheath Diameter
Effects of Menstrual Cycle on Optic Nerve Sheath Diameter in Patients Undergoing Laparoscopic Gynecologic Surgery
This observational study aims to evaluate the effect of menstrual cycle phase on optic nerve sheath diameter (ONSD) in women undergoing elective laparoscopic gynecologic surgery.
- Conditions
- Menstrual Cycle, Optic Nerve Sheath Diameter, Postoperative Nausea and Vomiting
- Trial name
- NCT07539831
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Konya City Hospital
Fertility, Mobile Applications
Smartphone vs Manual Interpretation of Biomarkers for Ovulation and Luteal Phase Detection (SMOM Study)
This study will compare different combinations of fertility signs (cervical mucus (CM), luteinizing hormone [LH], pregnanediol glucuronide [PDG], and basal body temperature [BBT]) to determine which are most reliable for…
- Conditions
- Fertility, Mobile Applications, Artifical Intelligence, Cervical Mucus
- Trial name
- SMOM (NCT07248046)
- Testing
- Premom App-Assisted Fertility Tracking
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bruyère Health Research Institute.