Clinical trials: Menstrual Flow Excessive
Menorrhagia
Comparison of Two Hysteroscopy Approaches
This randomized clinical trial compares two methods of diagnostic hysteroscopy: vaginoscopic hysteroscopy vs. traditional method.
- Trial name
- NCT00319410
- Testing
- vaginoscopic hysteroscopy
- Where
- Israel
- Volunteers
- 130 people
- Sponsor
- Wolfson Medical Center
Menorrhagia
Prevalence of Heavy Menstrual Bleeding in Female Population Living in Beijing
The purpose of the study is to estimate the prevalence of heavy menstrual bleeding (HMB) in females aged between 18 and 50 years old living in Bejing.
- Trial name
- NCT02304510
- Where
- China
- Volunteers
- 2,455 people
- Sponsor
- Peking University
Symptomatic Uterine Fibroids
Post Market TRUST - U.S.A. Study
This Post Market study is being conducted to compare the direct and indirect cost of three approaches (GFA, myomectomy, and uterine artery embolization) for the treatment of symptomatic uterine fibroids.
- Trial name
- NCT02163525
- Testing
- Global Fibroid Ablation (GFA), Abdominal or Laparoscopic Myomectomy, Uterine Artery Embolization (UAE)
- Where
- 9 sites in United States
- Volunteers
- 114 people
- Sponsor
- Acessa Health, Inc.
Uterine Fibroids (UF)
A Study to Evaluate Changes in Hair in Adult Participants Taking Oral Oriahnn Capsules With Heavy Menstrual Bleeding (HMB) Associated With Uterine Fibroids (UF)
Uterine Fibroids (UF) are benign smooth muscle neoplasms of the uterus that affect women of reproductive age. UFs are one of the leading causes of hospitalizations for gynecological disorders and often lead to hysterectomy.
- Trial name
- Pink Orchid (NCT06058728)
- Where
- United States
- Sponsor
- AbbVie
Heavy Menstrual Bleeding
Therapeutic Equivalence Trial of Two Hormonal-IUDs in Patients With Heavy Menstrual Bleeding
The primary objective of this study was to compare the efficacy of Test Product (Levosert) vs. Reference Product (Mirena® Bayer-Schering) based on the mean variation of menstrual blood loss volume in women with menorrhagia.
- Trial name
- LVS-20 (NCT01695902)
- Testing
- Levosert-20, Mirena
- Volunteers
- 280 people
- Sponsor
- Uteron Pharma S.A.
Menorrhagia
A Clinical Study of the Aqua Therapeutics Thermal Therapy Vapor Ablation System in Premenopausal Women With Abnormal Uterine Bleeding
Abnormal uterine bleeding (AUB) is defined as "flow outside of normal volume, duration, regularity, or frequency". Acute AUB is excessive bleeding that requires immediate intervention to prevent further blood loss.
- Trial name
- AQTH-EA-PIV-24 (NCT07877051)
- Testing
- Aqua Therapeutics Thermal Therapy Vapor Ablation System (ATTTVAS)
- Where
- 3 sites in Georgia
- Volunteers
- 43 people
- Sponsor
- Aqua Therapeutics, Inc.
Uterine Fibroids
Laparoscopic Occlusion of Uterine Vessels Compared to Uterine Fibroid Embolization for Treatment of Uterine Fibroids
Women with symptomatic uterine fibroids are treated either by Uterine Fibroid Embolization (UFE) or laparoscopic occlusion. The study hypothesis is that laparoscopic occlusion of uterine vessels and UFE have equal effect on…
- Trial name
- NCT00277680
- Testing
- Laparoscopic bilateral occlusion of uterine artery, Radiological embolization (UFE)
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Ullevaal University Hospital
Abnormal Uterine Bleeding
NOVasure EXpierences (NOVEX)
Heavy menstrual bleeding (HMB) affects approximately one in four women and imposes considerable social, emotional, physical and economic burdens.
- Trial name
- NCT06397898
- Testing
- Educational video
- Where
- Netherlands
- Volunteers
- 32 people
- Sponsor
- Maxima Medical Center
Menorrhagia, Heavy Menstrual Bleeding
Librata Endometrial Ablation Device Treatment to Reduce Menstrual Blood Loss
The objective of this study is to evaluate the safety and effectiveness of the endometrial ablation device Librata in reducing menstrual blood loss at 12 months post-treatment when used in pre-menopausal women with menorrhagia…
- Trial name
- LEADER (NCT03725306)
- Testing
- Librata
- Volunteers
- 200 people
- Sponsor
- LiNA Medical
Heavy Menstrual Bleeding
Dexamethasone for Excessive Menstruation
This study builds on previous research which has provided compelling evidence that deficient activity of glucocorticoids in the endometrium is a cause of increased menstrual bleeding.
- Trial name
- dexFEM (NCT01769820)
- Testing
- Dexamethasone
- Where
- United Kingdom
- Volunteers
- 123 people
- Sponsor
- University of Edinburgh
Menorrhagia
Trial of Homeopathy on Management of Menorrhagia
The purpose of this study is to compare outcomes and quality-of-life issues in the treatment of menorrhagia, this randomized double blind controlled trial compared homeopathy and placebo.
- Trial name
- NCT01460043
- Testing
- Homeopathy
- Volunteers
- 25 people
- Sponsor
- NMP Medical Research Institute
Menorrhagia, Heavy Menstrual Bleeding
Efficacy and Safety Study of XP12B in Women With Menorrhagia
The purpose of this study is to determine whether XP12B is effective and safe in the treatment of women with heavy menstrual bleeding associated with menorrhagia.
- Trial name
- NCT00386308
- Testing
- Tranexamic acid tablets
- Where
- 52 sites in United States
- Volunteers
- 196 people
- Sponsor
- Ferring Pharmaceuticals
Heavy Uterine Bleeding, Uterine Fibroids
Safety and Efficacy of Elagolix in Pre-Menopausal Women With Heavy Uterine Bleeding and Uterine Fibroids
The purpose of this proof-of-concept study is to assess the safety and effectiveness of elagolix versus placebo to reduce uterine bleeding associated with uterine fibroids, and to reduce fibroid volume and uterine volume in…
- Trial name
- NCT01441635
- Testing
- Elagolix, Estradiol/Norethindrone acetate (E2/NETA), Estradiol
- Volunteers
- 271 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Anemia
Comparison of the Safety and Efficacy of Intravenous Iron Versus Oral Iron in the Treatment of Anemia Secondary to Heavy Uterine Bleeding
This study compares of the safety and efficacy of intravenous iron vs oral iron in the treatment of anemia secondary to heavy uterine bleeding
- Trial name
- NCT00395993
- Testing
- Ferric Carboxymaltose (FCM), Ferrous Sulfate tablets
- Where
- United States
- Volunteers
- 456 people
- Sponsor
- American Regent, Inc.
Uterine Fibroids, Leiomyoma
Hysteroscopic Cryomyolysis for the Treatment of Submucosal Leiomyomata
The purpose of the current study is to evaluate the technical success, safety and procedure feasibility of hysteroscopic cryoablation treatment of symptomatic uterine fibroids in women who do not desire further pregnancies using…
- Conditions
- Uterine Fibroids, Leiomyoma, Menorrhagia
- Trial name
- NCT00731341
- Testing
- Cryoablation for the treatment of uterine fibroids
- Where
- Netherlands
- Volunteers
- 3 people
- Sponsor
- Boston Scientific Corporation
Menorrhagia
Relationship Between Bladder Distention and Hysteroscopy Application
The purpose of the study is to investigate the advantages and disadvantages of bladder filling during hysteroscopy procedure.
- Trial name
- NCT01848847
- Testing
- Hysteroscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Namik Kemal University
Adenovirus, Anesthesia
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Understudied drugs will be administered to children per standard of care as prescribed by their treating caregiver and only biological sample collection during the time of drug administration will be involved.
- Conditions
- Adenovirus, Anesthesia, Anxiety, Anxiolysis
- Trial name
- PTN_POPS (NCT01431326)
- Testing
- The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada and 3 more
- Volunteers
- 3,520 people
- Sponsor
- Daniel Benjamin
Menorrhagia
Post Approval NovaSure Essure Labeling Study
This post approval, observational study is being conducted to further evaluate the safety of the NovaSure Endometrial Ablation System when it is performed in the presence of Essure micro-inserts.
- Trial name
- PANEL (NCT01934244)
- Testing
- NovaSure Endometrial Ablation
- Where
- 14 sites in United States
- Volunteers
- 318 people
- Sponsor
- Hologic, Inc.
Anemia, Iron Deficiency, Heavy Menstrual Bleeding
IV Iron vs Oral Iron for Treatment of Anemia in Women With Abnormal Uterine Bleeding
This study investigates whether intravenous (IV) iron [Feraheme (ferumoxytol) injection)] is a better treatment than oral iron pills (ferrous sulfate) for correcting anemia in women who have heavy menstrual bleeding and anemia.
- Trial name
- NCT04205266
- Testing
- Ferumoxytol, Ferrous Sulfate
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Menorrhagia
Treatment of Copper Intra Uterine Device Associated Heavy Menstrual Blood Loss
Intrauterine contraceptive device is the most commonly reversible method used among women of reproductive age worldwide. Almost one in five married contraceptive users is currently using Intrauterine contraceptive device.
- Trial name
- NCT03139422
- Testing
- Tranexamic Acid 500 MG, Calcium Dobesilate
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Assiut University