Clinical trials: Menstruation, open to volunteers
Anaemia
Tranexamic Acid for Anaemia Trial
Anaemia is when the body does not have enough healthy red blood cells to carry oxygen. It is common in women because they lose blood every month during their periods.
- Trial name
- WOMAN-3 (NCT06519422)
- Testing
- Tranexamic Acid 500 MG
- Where
- 3 sites in Nigeria, Pakistan and 1 more
- Volunteers
- 4,000 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Laughter Yoga
Investigation of The Effect of Video-Assisted Laughter Yoga
This study is planned to examine the effect of video-assisted laughter yoga on pain and menstrual symptoms among students studying at a university in Türkiye.
- Trial name
- NCT07514546
- Testing
- Session 1: Laughter Yoga, Session 2: Laughter Yoga, Session 3: Laughter Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ataturk University
General Menstrual Discomfort
A Study of the Jovi Patch, Powered by Signal Relief, for the Improvement of General Menstrual Discomfort
This pilot study is testing whether a thin, flexible, drug-free patch called the Jovi Patch (powered by Signal Relief) can help reduce general menstrual discomfort (pain and related symptoms during periods).
- Trial name
- NCT07825558
- Testing
- Jovi Patch
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Signal Relief
Anemia
Menstruation and Anemia Research: A Community Health Study
This research is studying if a community-based, community health worker (CHW) led psychosocial intervention improves hemoglobin levels among Black/African American and/or Hispanic or Latino women with anemia compared to standard…
- Trial name
- MARCH (NCT07832526)
- Testing
- Standard of Care, Informational Series and follow-up support
- Where
- 2 sites in United States
- Volunteers
- 180 people
- Sponsor
- University of Michigan
Effect of Reflexology on Premenstrual Syndrome Symptoms
The Effect of Reflexology on Premenstrual Syndrome Symptoms, Pain and Quality of Life
This study was planned as a randomized controlled experimental study to examine the effect of reflexology on premenstrual syndrome symptoms, pain and quality of life in women with premenstrual syndrome between January 2025 and…
- Trial name
- NCT06961552
- Testing
- reflexology masaj group
- Volunteers
- 70 people
- Sponsor
- Saglik Bilimleri Universitesi
Postoperative Shivering
Menstrual Cycle and Postanesthetic Shivering
The goal of this observational study is to learn about the effect of menstrual cycle on postoperative shivering in women of fertile age.
- Trial name
- NCT06996977
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bozyaka Training and Research Hospital
Minimally Invasive Surgical Procedures, Abnormal Uterine Bleeding, Unspecified
Cyclobenzaprine for Postoperative Pain in Minimally Invasive Hysterectomy
Typical postoperative pain control after minimally invasive hysterectomy includes ibuprofen, acetaminophen, and a short course of narcotics.
- Conditions
- Minimally Invasive Surgical Procedures, Abnormal Uterine Bleeding, Unspecified, Adenomyosis of Uterus, Fibroid Uterus
- Trial name
- NCT07664956
- Testing
- Cyclobenzaprine
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Christiana Care Health Services
Premenstrual Dysphoric Disorder
Emotion Regulation-based Internet-delivered Cognitive Behavioural Therapy for Premenstrual Dysphoric Disorder
Premenstrual dysphoric disorder (PMDD) is a debilitating cyclic mental disorder affecting about 2-5% of women of reproductive age.
- Trial name
- Premensis-s (NCT06496139)
- Testing
- Therapist-guided internet-delivered cognitive behavioural therapy
- Where
- Sweden
- Volunteers
- 164 people
- Sponsor
- Uppsala University
Infertility (IVF Patients), Infertility Assisted Reproductive Technology
Quantifying Uterine Elastography in Menstruating Women
This study is aiming to characterize the elasticity of the female reproductive tract including the uterus, cervix and ovary using shear wave elastography at different times during the menstrual cycle and define the standard…
- Trial name
- QUEST (NCT06816381)
- Testing
- Shear wave elastography measurements
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Pain Perception in Endodontic Treatment, Menstrual Cycle
Menstrual Cycle, Menopause, and Pain Perception During Endodontic Treatment
The goal of this observational study is to investigate whether menstrual cycle phases and menopausal status are associated with pain perception in patients undergoing endodontic treatment.
- Conditions
- Pain Perception in Endodontic Treatment, Menstrual Cycle, Menopause
- Trial name
- NCT07850167
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Menstrual Cycle, Ovulation
Apple Women's Health Study
This is an observational longitudinal study to advance the understanding of menstrual cycle and gynecologic health conditions including PCOS, infertility and breast cancer.The study will be hosted within the Research…
- Conditions
- Menstrual Cycle, Ovulation, Menstruation, Polycystic Ovary Syndrome
- Trial name
- NCT04196595
- Where
- United States
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- Apple Inc.
Dysmenorrhea, Adenomyosis
Electroacupuncture for Dysmenorrhea Secondary to Adenomyosis
The aim of this study is to preliminarily evaluate the is to assess the effects and safety of electroacupuncture for moderate to severe dysmenorrhea secondary to adenomyosis.
- Conditions
- Dysmenorrhea, Adenomyosis, Electroacupuncture
- Trial name
- NCT06364592
- Testing
- Electroacupuncture
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Polycystic Ovarian Syndrome (PCOS)
This Study Aims to Evaluate Whether Milamend's Product Could Improve Hormone Balance in Women Who Suffer From Self-reported PCOS Symptoms.
The rationale for this study is to observe the impact of a consumer-grade commercially available product called Milamend Hormone Balance on quality of life and hormonal health in women with self-reported symptoms associated with…
- Trial name
- NCT07764328
- Testing
- A dietary supplement powder for women
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Mila Mend Inc.
Menorrhagia Due to Benign Causes
Reframing Endometrial Physiology by Advanced Integrated Research
Heavy menstrual bleeding (HMB) affects 1 in 3 women and can significantly impact quality of life. Despite its prevalence, there is no accessible and accurate diagnostic test.
- Trial name
- REPAIR (NCT07557992)
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Sexual Transmitted Disease, Vaginosis, Bacterial
Impact of Internal Menstrual Protections on Immunity and Vaginal Microbiota
The availability, effectiveness, and safety of menstrual protection represent a key public health issue. However, research on women's menstrual and sexual health remains extremely limited.
- Conditions
- Sexual Transmitted Disease, Vaginosis, Bacterial, Mycosis, Urogenital Disease
- Trial name
- CUPS2 (NCT07199998)
- Testing
- Samples collection (whole blood, urine, vaginal and cervical cells)
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre National de la Recherche Scientifique, France
Dysmenorrhea, Pain
The Effect of Distraction Techniques Used in Intramuscular (IM) Injections on Pain in Adolescents Presenting to the Emergency Department With Dysmenorrhea: A Randomized Controlled Study
Brief Summary: This study investigates the effectiveness of non-pharmacological techniques for managing dysmenorrhea (menstrual pain) in adolescents.
- Conditions
- Dysmenorrhea, Pain, Distraction Methods
- Trial name
- "HSTT-SB Dysme (NCT06842329)
- Testing
- Halfer Skin Tape Technique, ShotBlocker Technique, Standard Intramusculer injection
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Duygu MEZDE
IUD; Complications, Mechanical, Menstrual Cup
Pilot Study of Suction as a Mechanism of IUD Expulsion With Concomitant Menstrual Cup Use
This study will provide pilot data examining suction as a mechanism of IUD displacement with menstrual cup use. The investigator hypothesize that manufacturer-recommended menstrual cup insertion and removal by breaking the seal…
- Trial name
- NCT05254041
- Testing
- Menstrual Cup Removal
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Diabetes Mellitus, Type I, Menstruation
Influence of Menstrual Cycle Phases on the Glycemic Control of Aerobic or HIIT Exercise in Adult Women With Type 1 Diabetes
Continuous glucose monitors, as a technology that aims to improve glycaemic control in patients with type 1 diabetes, must always adjust to changes in blood glucose levels in these patients, e.g. during sporting activities.
- Trial name
- DIABETEXX/2 (NCT06729242)
- Testing
- Aerobic session, HIIT session
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Valencia
Dysmenorrhea Primary
The Effect of Hydrogen-Rich Water on Dysmenorrhea and Menstrual Symptom Severity
The study will include hydrogen-rich water and control groups. Young women with severe primary dysmenorrhea will be recruited from Ankara University.
- Trial name
- NCT07865000
- Testing
- Hydrogen-rich water consumption, Drinking water consumption
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Menekşe Nazlı AKER
PMS, PMDD
Microdosing LSD in Women With Premenstrual Disorders
The investigators aim to investigate the role of the serotonin 2A receptor in women with premenstrual disorders. This study uses a double-blind, randomized, controlled design with 3 arms: Intervention 1: 10 micg LSD for ~10 days…
- Trial name
- L4Her (NCT07189299)
- Testing
- LSD 10 μg every Day, LSD 10 μg every other day
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- Friederike Holze