Clinical trials: Menstruation Disturbances
Endometriosis
Study to Evaluate the Long-Term Safety and Efficacy of Elagolix in Adults With Moderate to Severe Endometriosis-Associated Pain
A randomized study evaluating the continued safety and efficacy of elagolix in the management of moderate to severe endometriosis-associated pain in pre-menopausal women.
- Trial name
- NCT01760954
- Testing
- Elagolix
- Volunteers
- 506 people
- Sponsor
- AbbVie
Uterine Leiomyoma, Uterine Fibroids
Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids
The objectives of this randomized withdrawal study are to evaluate the long-term efficacy and safety of the combination of relugolix, estradiol (E2) and norethindrone acetate (NETA), once daily, for up to 104 weeks in patients…
- Trial name
- NCT03751124
- Testing
- Relugolix, Estradiol/norethindrone acetate
- Where
- 104 sites in United States, Brazil and 6 more
- Volunteers
- 229 people
- Sponsor
- Myovant Sciences GmbH
Primary Dysmenorrhea
Tele-Pilates for Primary Dysmenorrhea
This randomized controlled trial investigates the effectiveness of a synchronized tele-Pilates program on menstrual pain, symptom severity, physical disability, and trunk muscle endurance in women with primary dysmenorrhea (PD).
- Trial name
- NCT07335926
- Testing
- Tele-Pilates Exercise program, standardized menstrual health education online
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Atlas University
Menstrual Problem, Covid19
Menstrual Cycle-induced Pain, Fatigue and Anxiety in Women Suffered From COVID-19
The effects of COVID-19 on body systems and functions are still being investigated. ACE 2, which plays a key role in the entry of the COVID-19 virus into the cell, is also highly expressed in the ovary, uterus, vagina, and…
- Conditions
- Menstrual Problem, Covid19, Fatigue
- Trial name
- NCT04806815
- Testing
- A survey of 60 questions was created through the internet-based 'Google Forms surveys' site.
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Biruni University
Endometriosis
Extension to Study on Efficacy and Safety of Linzagolix for the Treatment of Endometriosis-associated Pain
The primary objective of this extension study is to assess the maintenance of efficacy of linzagolix administered orally once daily for up to an additional 6 months (for up to 12 months of treatment in total) in women who have…
- Trial name
- EDELWEISS 5 (NCT04372121)
- Testing
- 75 mg linzagolix tablet, 200 mg linzagolix tablet, Add-back capsule (E2 1 mg / NETA 0.5 mg)
- Where
- 25 sites in United States, Canada and 1 more
- Volunteers
- 30 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Metrorrhagia, Menorrhagia
Surgical Success After Laparoscopic vs Abdominal Hysterectomy
The purpose of the proposed pilot study is to investigate the effectiveness, cost, safety, and long-term impact on quality of life of laparoscopic hysterectomy (LH) in relation to abdominal hysterectomy (AH) for the treatment of…
- Conditions
- Metrorrhagia, Menorrhagia, Leiomyoma, Adenomyosis
- Trial name
- NCT01793584
- Testing
- Laparoscopic hysterectomy, Abdominal hysterectomy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Menorrhagia
A Swedish Questionnaire Study to Investigate the Perception of Menstrual Bleedings
This field based, questionnaire study will document observational data on womens perception of menstrual bleeding in a cross-section of women in Sweden. Each subject will complete the questionnaire at one occasion.
- Trial name
- NCT01643304
- Testing
- No drug
- Where
- Sweden
- Volunteers
- 1,547 people, healthy volunteers welcome
- Sponsor
- Bayer
Eating Disorders, Hypoestrogenemia
The Role of Estrogen in the Neurobiology of Eating Disorders
This is a randomized, double blind, placebo-controlled study of the effects of transdermal estradiol versus placebo on cognitive flexibility, reward processing, and eating disorder pathology in hypoestrogenemic female adolescents…
- Trial name
- NCT03740204
- Testing
- 17-β estradiol transdermal patches with cyclic progesterone
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Massachusetts General Hospital
Artificial Intelligence, Self-care
AI-Based Education and Menstrual Health Behaviors in Adolescents
This study is designed as a randomized controlled trial aiming to compare the effectiveness of different educational approaches in improving dysmenorrhea self-care and genital hygiene behaviors among adolescent girls.
- Conditions
- Artificial Intelligence, Self-care, Dysmenorrhea, Genital Hygiene Behaviors
- Trial name
- NCT07598929
- Testing
- AI-Supported Mobile Education, Face-to-Face Education, Brochure-Based Education
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Premenstrual Syndrome
Evaluation of Efficacy/Safety of EVE-PMS Skin Test Panel
The EVE-PMS technology is intended for determination of intolerance or sensitivity to sex hormones, among women suffering from severe PreMenstrual Syndrome (PMS).
- Trial name
- NCT00866437
- Testing
- Skin test panel
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- EVE Medical Systems Ltd.
Adenomyosis
Norwegian Adenomyosis Study I
Adenomyosis is characterized by the appearance of endometrial cells in the muscular layer of the uterus. It affects about 15-20% of the female population.
- Trial name
- NAPPED I (NCT02201719)
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Primary Dysmenorrhea
Effect of HIIT VS Yoga on Level of Pain, Catastrophizing and QoL in Dysmenorrhea
This study is aimed at determining the effect of high intensity interval training VS yoga on pain, catastrophizing and quality of life among young females with dysmenorrhea.
- Trial name
- NCT05010967
- Testing
- High intensity interval training, Yoga Training
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Premenstrual Syndrome, Acupressure
Acupressure and Training for Coping With PMS
The study was conducted to determine the effect of acupressure and training, given to women under the guidance of health belief model for coping with premenstrual syndrome, on the premenstrual symptoms and quality of life.
- Trial name
- NCT03899207
- Testing
- training +acupressure, training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 199 people
- Sponsor
- Adiyaman University Research Hospital
Premenstrual Syndrome, Quality of Life
The Effect of Laughter Yoga on Premenstrual Symptoms and Quality of Life in Midwifery Students
The research was planned as a prospective, randomized controlled experimental study to determine the effect of laughter yoga applied to midwifery students on premenstrual symptoms (PMS) and quality of life.
- Trial name
- NCT05859399
- Testing
- Laughter yoga
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Mersin University
Premenstrual Syndrome-PMS
Efficacy of a Food Supplement in Relieving Premenstrual Syndrome Symptoms
The aim of this clinical trial, funded by Activ'Inside, is to evaluate the efficacy of a food supplement in relieving Premenstrual Syndrome (PMS) Symptoms.
- Trial name
- NCT07013539
- Testing
- plant extract
- Where
- 6 sites in Italy
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Activ'inside
Inflammatory Bowel Diseases, Contraception
Hormonal Influences on Inflammatory Bowel Diseases
Of the 1.8 million females with inflammatory bowel diseases (IBD) in the US, over half of those who are premenopausal suffer from cyclical menstrual-related IBD symptoms, regardless of how well their disease is controlled.
- Conditions
- Inflammatory Bowel Diseases, Contraception, Menstrual Problem
- Trial name
- NCT05610527
- Testing
- Proposed study design and randomization scenarios, Repeated measures of validated Inflammatory Bowel Disease Patient Reported Outcome Instruments, Inflammatory marker collection and assessment for correlation with PRO responses and menstrual timing
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Utah
Arterial Hypertension, Postmenopausal; Menorrhagia
Effects of Resistance Training Intensity on Cardiovascular Parameters of Hypertensive Women
The goal of this clinical trial is to understand about the effects of resistance training (RT) intensity on cardiovascular parameters in postmenopausal women with systemic arterial hypertension (SAH).
- Conditions
- Arterial Hypertension, Postmenopausal; Menorrhagia, Cardiovascular Diseases
- Trial name
- NCT06538454
- Testing
- Resistance training
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- University of Sao Paulo
Dysmenorrhea
A Comparison Study of Pain Relief From Dysmenorrhea Between the Vipon Tampon and Ibuprofen
The purpose of this study is to compare the Vipon tampon with ibuprofen in relieving pain in women with dysmenorrhea. Subjects completed a total of 4 treatment intervals; each subject was randomized to use the VIPON as their…
- Trial name
- NCT00951561
- Testing
- Vipon, Ibuprofen
- Where
- 2 sites in United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Another Way Products
Primary Dysmenorrhea
Chinese Herbal Sachet Inhalation for Primary Dysmenorrhea in Female College Students
Primary dysmenorrhea (painful menstrual periods without an underlying disease) is very common in female college students and can affect sleep, mood, study and daily life.
- Trial name
- NCT07778849
- Testing
- Traditional Chinese herbal sachet (aromatic inhalation)
- Where
- China
- Volunteers
- 82 people
- Sponsor
- Macao Polytechnic University
Menstruation Disturbances, Dysmenorrhea Primary
Lifestyle Influence on Primary Dysmenorrhea
There is a correlation between the effect of lifestyle and prevalence and severity of primary dysmenorrhea. We will collect data through an online questionnaire.
- Trial name
- NCT04583943
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Jordan