Clinical trials: Mental
Breast Cancer, Circadian Rhythms
The Effects of Light Therapy to Treat Cancer-related Side Effects
Severe fatigue, depression, sleep problems and cognitive impairment are the most commonly reported side effects of cancer treatment.
- Conditions
- Breast Cancer, Circadian Rhythms, Fatigue, Sleep Disturbance
- Trial name
- NCT04418856
- Testing
- Light Glasses (Experimental), Light Glasses (Comparison)
- Where
- Iceland
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Reykjavik University
Cancer, Cancer Pain
Effect of Music on Pain and Anxiety in Palliative Cancer Patients
Background: Cancer patients receiving palliative care often endure a variety of distressing symptoms, most notably pain and anxiety.
- Conditions
- Cancer, Cancer Pain, Palliative Care, Anxiety
- Trial name
- NCT07262151
- Testing
- Music Application, Procedures for the Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Karamanoğlu Mehmetbey University
Major Depressive Disorder
A Pilot Study of Creatine Monohydrate as an Augmenting Agent for ECT in Persons With Major Depressive Disorder
We propose to determine if augmentation of electroconvulsive therapy (ECT) utilized for the treatment of major depressive disorder (MDD) with daily oral creatine will lead to an accelerated response to treatment, an overall…
- Trial name
- NCT04504253
- Testing
- Creatine monohydrate
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Utah
Alcoholism, Cocaine Dependence
Topiramate for Alcohol and Cocaine Dependence
The primary purpose of this study is to test the effectiveness of topiramate for the treatment of combined alcohol and cocaine dependence. Topiramate is approved for the treatment of seizures.
- Trial name
- TOP2 (NCT00167245)
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Kyle Kampman
Anxiety, Depression
Sudarshan Kriya Yoga and Cardiac Autonomic Control in Patients With Anxiety-Depression Disorders
The effects of Sudarshan Kriya Yoga (SKY) on autonomic function in patients with anxiety-depression disorders is unknown. Thus, the authors will investigate cardiac autonomic control in a population of patients with…
- Trial name
- NCT02828072
- Testing
- SKY therapy, usual drug therapy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Milan
Glioblastoma, Low Grade Glioma
Mind-Body Intervention in Glioma Couples
This trial studies how well a couple-based mind body program works in improving spiritual, psychosocial, and physical quality of life in patients with high or low grade glioma or tumors that have spread to the brain and their…
- Conditions
- Glioblastoma, Low Grade Glioma, Malignant Glioma, Metastatic Malignant Neoplasm in the Brain
- Trial name
- NCT03244995
- Testing
- Mind-Body Intervention Procedure, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Fibromyalgia, Psychological Trauma
Augmentation of EMDR With tDCS in the Treatment of Fibromyalgia
Fibromyalgia (FM) is a generalized, widespread chronic pain disorder and has an estimated prevalence of 2%-4% in the general population.
- Conditions
- Fibromyalgia, Psychological Trauma, Depressive Symptoms, Anxiety
- Trial name
- NCT04084795
- Testing
- Eye Movement Desensitization and Reprocessing therapy, transcranial Direct Current Stimulation
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Parc de Salut Mar
Autism Spectrum Disorder (ASD)
Neuromotor Task Training in Autistic Children With Motor Difficulties
The goal of this clinical study is to learn whether Neuromotor Task Training (NTT) may help improve functional motor skills in autistic children who have motor difficulties.
- Trial name
- NTT-SCED (NCT07797439)
- Testing
- Neuromotor Task Training
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Groupe Hospitalier Nord-Essonne
Schizophrenia
Staccato Loxapine in Agitation (Proof of Concept)
The purpose of this study is to assess efficacy and safety of Staccato Loxapine in the treatment of acute agitation in schizophrenic patients.
- Trial name
- NCT00369577
- Testing
- Inhaled Loxapine 5 mg, Inhaled Loxapine 10 mg
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- Alexza Pharmaceuticals, Inc.
Pain, Postpartum Depression
Postpartum Perineal Pain After Obstetric Anal Sphincter Injuries
Obstetric anal sphincter injuries (OASIS) encompass both third and fourth degree perineal tears. These tears can have a significant impact on women's quality of life in the short and long term.
- Trial name
- NCT03470675
- Testing
- Epidural saline + IV saline, Epidural morphine 3 mg + IV saline, Epidural morphine 3 mg + IV ketamine 0.3 mg/kg
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Northwestern University
Nocturnal Enuresis
A New Check-list Method for Nocturnal Enuresis
The study is aimed to demonstrate the benefits of newly formed written check-list of behavioral instructions and investigate its effects on parent's awareness, consciousness and motivation toward MNE.
- Trial name
- NCT03510975
- Testing
- desmopressin melt form 120 μg, Verbal behavioral therapy, Behavioral therapy with written check-list
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ankara Training and Research Hospital
Physical Activity, Incentives
TAKing Steps for Incentives
The purpose of this study is to test the overall effects of incentives on physical activity among older taxi drivers, and whether mental accounting exists in this context.
- Trial name
- TAKSI (NCT01892475)
- Testing
- Incentive-based physical activity program, 3-month follow up
- Where
- Singapore
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Duke-NUS Graduate Medical School
Sexual Dysfunction, Sexual Arousal Disorder
Clitoral Therapy Device in Alleviating Sexual Dysfunction After Genital Mutilation.
The aim of this study to determine the effect of clitoral therapy device EROS device/ on sexual dysfunction after genital mutilation.
- Trial name
- NCT05039775
- Testing
- EROS device, Psychosexual support
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Badr University
Sleep Disorders, HIV Infections
Patient Preference, Sleep Quality, and Anxiety/Depression: A Comparison of Raltegravir and Efavirenz
Efavirenz causes neuropsychiatric side effects and sleep disturbance, including vivid dreams, dizziness, and abnormal tiredness.
- Trial name
- Switch-ER (NCT00944957)
- Testing
- Raltegravir for the first 2 weeks, Efavirenz for the last 2 weeks, Efavirenz for the first 2 weeks
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Geneva
Opioid Use Disorder
KIOS Mobile App Evaluation
Evaluation of a mobile medical app (KIOS) vs. treatment as usual for the treatment of opioid use disorder (OUD).
- Trial name
- NCT06212557
- Testing
- KIOS App, KIOS App education, Treatment as usual
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Pathological Gambling
Deep Low-Frequency Repetitive Transcranial Magnetic Stimulation for Cessation of Pathological Gambling
Pathological gambling (PG) is characterized by a persistent pattern of continued gambling behavior despite its adverse consequences.
- Trial name
- NCT01154712
- Testing
- Real Deep TMS
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- BeerYaakov Mental Health Center
Virtual Reality, Anxiety
The Effect of Virtual Reality Application on Anxiety and Patient Satisfaction During Intrauterine Insemination (IUI)
This study will conduct as a randomized pretest-posttest study to examine the effect of virtual reality glasses (VRG) application during the IUI procedure on anxiety and patient satisfaction.
- Conditions
- Virtual Reality, Anxiety, Patient Satisfaction, Intrauterine Insemination (IUI)
- Trial name
- (IUI) (NCT06346730)
- Testing
- Virtual reality glasses to intervention group
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Working Memory, Consolidation/Recconsolidation Memory
Theories of Working Memory and Consolidation/RECOnsolidation in the Process of Resorption of Post-traumatic Symptoms.
EMDR is a psychotherapeutic approach recommended by the World Health Organization (WHO) for the treatment of disorders such as post-traumatic stress disorder, anxiety, depression and, more generally, psychological distress.
- Conditions
- Working Memory, Consolidation/Recconsolidation Memory, Eye Movement Desensitization and Reprocessing, Alterning Bilateral Stimulation
- Trial name
- NCT06469333
- Testing
- Eye movements (EM), Auditory stimulations, Tactile stimulations
- Where
- France
- Volunteers
- 154 people
- Sponsor
- University of Lorraine
Mental Health, School-age Children
Active Breaks on Mental Health and Classroom Climate in Chilean Schoolchildren Aged 6 to 10
Background: The incidence of mental health issues in children is increasing worldwide. In Chile, a recent surge in reports of deteriorating mental health among school populations and an increase in complaints related to poor…
- Conditions
- Mental Health, School-age Children, School Health
- Trial name
- NCT06423404
- Testing
- the Experimental Group, receiving a 12-week program of video-guided active breaks with curricular content in the school classroom
- Where
- 2 sites in Chile
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Universidad de Concepcion
Opiate Dependence
ALK21-004: Single-dose Opiate Challenge of Medisorb® Naltrexone (VIVITROL®) in Adults Who Use Opioids
This was a Phase 2, multicenter, randomized, double-blind pilot study in opioid-using adults to assess the presence, duration, and degree of opiate blockade as well as the safety and tolerability of Medisorb® naltrexone…
- Trial name
- NCT01218984
- Testing
- Medisorb naltrexone 75 mg, Medisorb naltrexone 150 mg, Medisorb naltrexone 300 mg
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Alkermes, Inc.
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