Clinical trials: Mental
Oral Frailty, Mild Cognitive Impairment (MCI)
Oral Motor and Cognitive Dual-Task Training (OMCDT) Program for Improving Oral and Cognitive Functions Among People With Oral Frailty
The goal of this clinical trial is to proposes a novel Oral Motor and Cognitive Dual-Task Training (OMCDT) program that combines both oral motor exercises and cognitive tasks to improve brain and oral function at the same time.
- Conditions
- Oral Frailty, Mild Cognitive Impairment (MCI), Moderate Cognitive Impairment
- Trial name
- OMCDT (NCT07733726)
- Testing
- Oral Motor and Cognitive Dual-Task Training (OMCDT), Oral motor exercise
- Where
- 2 sites in Hong Kong
- Volunteers
- 66 people
- Sponsor
- The Hong Kong Polytechnic University
Posttraumatic Stress Disorder
Dose Optimization of MDMA-Assisted Therapy for PTSD
This open label, within-subjects dose optimization trial will investigate the optimal number of MDMA-Assisted Therapy treatment cycles (i.e., one MDMA session and three integration sessions) in a sample of U.S.
- Trial name
- DosOp (NCT06418178)
- Testing
- Midomafetamine, Psychotherapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Bronx VA Medical Center
Cognitive Impairment, Mild Cognitive Impairment
Evaluation of Cognitive and Physical Training on MCI Elders
This study examines the impact of combining cognitive and physical training, recognizing that daily living often requires individuals to perform multiple tasks simultaneously.
- Trial name
- NCT06572878
- Testing
- Cognitive training, Physical training, Combined cognitive and physical training
- Volunteers
- 144 people
- Sponsor
- Taipei Medical University
Accidental Overdose of Opiate
Remote Intervention to Prevent Overdose
This Type 1 hybrid effectiveness-implementation randomized controlled trial, A Remote Intervention to Prevent Overdose among People who Use Stimulants and/or Opioids, aims to address the United States opioid crisis driven by…
- Trial name
- NCT07128485
- Testing
- Overdose prevention resources, Overdose prevention education
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Alabama at Birmingham
Trichotillomania
Trichotillomania: Group Cognitive-Behavioral Therapy
Objective: Trichotillomania is a psychiatric condition characterized by chronic pulling and plucking of one's own hair. Cognitive behavioral therapy shows promise as a treatment.
- Trial name
- NCT01968343
- Testing
- Cognitive-behavioral therapy., Supportive therapy.
- Where
- Brazil
- Volunteers
- 44 people
- Sponsor
- University of Sao Paulo
Posttraumatic Stress Disorder
Deep Brain Stimulation of the Amygdala for Combat Post-Traumatic Stress Disorder
Posttraumatic stress disorder (PTSD) affects approximately 30 % of American veterans returning from Iraq and Afghanistan. Although the current therapy is effective, a percentage of patients will fail to improve and will develop…
- Trial name
- NCT02091843
- Testing
- DBS of the Basolateral Nucleus of the Amygdala, Medtronic Activa PC DBS of the Basolateral Nucleus of the Amygdala
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- VA Greater Los Angeles Healthcare System
Impairment, Cognitive, Impairment of Attention
High Confusion: Cannabis & Driving
This study is being done to assess the feasibility of administrating Δ9-THC and Δ8-THC isolates and simultaneously adopting several data harmonization measures to generate uniquely translatable data.
- Conditions
- Impairment, Cognitive, Impairment of Attention, Impairment, Psychomotor
- Trial name
- NCT06236815
- Testing
- Delta-9-THC, Delta-8-THC
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Schizophrenia
Training-induced Cerebral Reorganization in Schizophrenia
The purpose of this study is to reveal the effects of computer-aided cognitive-auditory training on cerebral reorganization in schizophrenia.
- Trial name
- NCT00695708
- Testing
- Brain Fitness Program, Cogpack
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Substance Use Disorders, Criminal Behavior
Improving Outcomes in Social Services Through Routine Outcome Monitoring and Systematic Client Feedback
In this project the investigators want to test whether a new method FIT (Feedback informed treatment) can improve the interventions people receive through social services.
- Conditions
- Substance Use Disorders, Criminal Behavior, Domestic Violence, Social Care
- Trial name
- NCT07303608
- Testing
- Feedback informed treatment (FIT), Treatment as usual (TAU)
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Karolinska Institutet
Pregnancy, Pregnancy, Complications
Michigan Healthy Mom (MI-MOM) Pregnancy Improvement Web Application Trial
The purpose of this research study is to see if using the MI MOM App improves pregnancy and postpartum health. There are two study groups, where one group is "treatment as usual" and the other is the "MI MOM App" group.
- Conditions
- Pregnancy, Pregnancy, Complications, Pregnancy Outcomes
- Trial name
- MI-MOM App (NCT07213284)
- Testing
- MI MOM App
- Where
- 8 sites in United States
- Volunteers
- 500 people
- Sponsor
- Michigan State University
Bipolar Disorder, Time Restricted Eating
Healthy Lifestyles in Bipolar Disorder: Bay Area Study
The goal of this clinical trial is to understand how level of adherence with time-restricted eating (TRE) predicts change in diurnal rhythms (as measured using the amplitude of diurnal peripheral clock gene expression), and how…
- Trial name
- NCT06555406
- Testing
- Time-restricted eating for 8 weeks
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of California, Berkeley
Obsessive Compulsive Disorder
Comparing the Effectiveness of Two Family-based Therapies in Treating Young Children With Obsessive-Compulsive Disorder
This study will compare the effectiveness of family-based cognitive behavioral therapy to family-based relaxation therapy in treating young children with obsessive-compulsive disorder.
- Trial name
- NCT00533806
- Testing
- Cognitive Behavior Therapy, Relaxation Therapy
- Where
- 3 sites in United States
- Volunteers
- 127 people
- Sponsor
- Rhode Island Hospital
Depression, Postpartum, Postpartum Care
Healing at Home 2.0 - Enhanced Chat Tool for Lowering Postpartum Depression
The purpose of the study is to determine if access to a text-message based holistic chatbot support program "Healing at Home 2.0" decreases depressive symptoms as measured by the Edinburgh Postnatal Depression Scale (EPDS)…
- Trial name
- HEALED (NCT06877104)
- Testing
- Healing @ Home Program (H@H 2.0)
- Where
- United States
- Volunteers
- 156 people
- Sponsor
- University of Pennsylvania
Posttraumatic Stress Disorder, Tobacco Dependence
Tobacco Treatment as Augmentation for Cognitive Processing Therapy for PTSD
The purpose of this study is to examine whether tobacco affects recovery from PTSD. There are 3 goals of the study; (1) to test if quitting tobacco prior to PTSD treatment affects treatment success, (2) to test how PTSD symptoms…
- Trial name
- NCT02012452
- Testing
- Tobacco treatment, Health Education
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- VA Office of Research and Development
Alzheimer Disease, Glucose Metabolism
Feasibility Study of a Community Pilot Project for the Prevention of Alzheimer's Disease: the KetoHome Study.
The purpose of this study is to assess whether it is possible to carry out a research project with a nutritional intervention in senior's residence.
- Trial name
- KetoHome (NCT05642052)
- Testing
- low carb diet, Regular diet
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Opioid Use, Opioid Use Disorder
Gut Microbiota Dysbiosis in Opioid Use Disorders: Implications for Clinical Symptoms and Relapse Rate.
This study will aim to investigate the gut microbiota in Egyptian patients with opioid use disorders and correlate microbiota bacterial abundance with clinical data.
- Conditions
- Opioid Use, Opioid Use Disorder, Opioid Dependence
- Trial name
- NCT06231849
- Testing
- stool analysis
- Volunteers
- 52 people
- Sponsor
- Assiut University
Nicotine Addiction
Effects of Brief Training on Craving Regulation
The investigators propose that brief training in regulation of craving may increase the efficacy of smoking cessation, but that training in cognitive vs.
- Trial name
- NCT02153749
- Testing
- Cognitive Regulation of Craving, Mindfulness-Based Regulation of Craving
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Yale University
Bedwetting
Hand & Foot Nocturnal Enuresis TENS Study
The investigators believe in order to strengthen the evidence in support of transcutaneous foot stimulation in this population the investigators need to move forward with a randomized comparison study using the TENS device on the…
- Trial name
- NCT02747849
- Testing
- TENS
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Rajeev Chaudhry
Progressive Relaxation Exercise, Hernia
Effects of Relaxation Exercises on Fear of Movement, Pain, and Quality of Life in Lumbar Disc Herniation Patients
This study evaluates whether progressive relaxation exercises can reduce fear of movement, pain, and improve quality of life in patients with lumbar disc herniation.
- Conditions
- Progressive Relaxation Exercise, Hernia, Pain, Kinesiophobia
- Trial name
- NCT07419958
- Testing
- progressive relaxation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Hasan Kalyoncu University
Anxiety, Stress
Impact of Play Interventions on Stress and Anxiety Using EEG and AI.
This project will target university students during their exam periods, whether midterms, finals, regular exams, or make-up exams, as this is a time particularly sensitive to academic stress.
- Trial name
- ILOS-WEEG (NCT07555158)
- Testing
- playful intervention
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
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