Clinical trials: Mental
Hypertensive Nephropathy, Self-management
Effectiveness of Implementation of a Patient-centered Self-management Program in Patients With Hypertensive Nephropathy
This study is a 2-years project. The year 1 project: to assess the effectiveness of implementation of the program in patients with HN.
- Conditions
- Hypertensive Nephropathy, Self-management, Self-efficacy, Mental Health Wellness 1
- Trial name
- NCT04633993
- Testing
- PCSMP
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Psychological Stress, Mental Fatigue
Psychological Impacts of Exercise Snacks Versus Traditional Exercise: A Comparative Study
This study investigates the comparative psychological impacts of a high-frequency "Exercise Snacks" (ESG) protocol versus a traditional continuous exercise (TEG) regimen on healthy young adults.
- Conditions
- Psychological Stress, Mental Fatigue, Cognitive Dysfunction, Emotional Well-being
- Trial name
- ES (NCT07666893)
- Testing
- Exercise Snacks Group (ESG), Traditional Exercise Group (TEG)
- Where
- China
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Lincoln University College
Attention Deficit Disorder With Hyperactivity
Effects of a Novel Neurofeedback Protocol on ADHD Subcomponents
Mounting evidence suggests that closed-loop brain-training, commonly known as neurofeedback (NFB), may represent a new therapeutic opportunity for patients with Attentional Deficit/Hyperactivity Disorder (ADHD), which manifests…
- Trial name
- NFB@HOME (NCT04408521)
- Testing
- NEUROFEEDBACK, CONTROL
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- University Hospital, Geneva
Alcohol Abuse, Alcoholism
Consequences of At-risk Alcohol Consumption in ICU Patients
At-risk drinking is known to cause a high incidence of alcohol withdrawal syndrome which has a high impact on morbidity and mortality.
- Trial name
- NCT03565016
- Testing
- no interventional study
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Nantes University Hospital
Non-24-Hour Sleep-Wake Disorder
Tasimelteon for the Treatment of Non-24-hour Sleep-Wake Disorder (N24HSWD) in Blind Individuals With no Light Perception
The purpose of this study is to evaluate the safety of tasimelteon in male and female patients who suffer from Non-24-Hour Sleep-Wake Disorder.
- Trial name
- NCT01429116
- Testing
- tasimelteon
- Where
- 22 sites in United States
- Volunteers
- 200 people
- Sponsor
- Vanda Pharmaceuticals
Self Injurious Behavior, Adolescent Behavior Problem
IMAGINATOR 2.0: Co-design and Early Evaluation of a Novel Blended Digital Intervention Targeting Self-harm in Young People
This study aims to investigate acceptability and feasibility of a new version of the Imaginator intervention, Imaginator 2.0, targeting self-harm behaviour in young people aged 12-25 under mental health services in the UK.
- Conditions
- Self Injurious Behavior, Adolescent Behavior Problem, Child Behavior Problem, Mental Health Disorder
- Trial name
- IMAG2 (NCT06311084)
- Testing
- Imaginator 2.0
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- Imperial College London
Lower Limb Amputation, Prosthesis Users
Dual-Task Balance Training in Traumatic Lower-Limb Prosthesis Users
This randomized controlled trial will evaluate the effectiveness of dual-task balance training on balance, mobility, and mental health among traumatic lower-limb prosthesis users in the Gaza Strip.
- Conditions
- Lower Limb Amputation, Prosthesis Users, Balance Impairment, Mobility Limitations
- Trial name
- DTBT-LLA (NCT07706452)
- Testing
- Dual-Task Balance Training, Standard Rehabilitation
- Where
- Palestinian Territories
- Volunteers
- 63 people
- Sponsor
- Al-Azhar University - Gaza
Eating Disorders, Psychiatric Comorbidities
Structural Brain Volumetry Changes in Eating Disorders.
The goal of this observational study is to investigate the relationship between structural brain changes and psychiatric comorbidities in individuals diagnosed with eating disorders (EDs).
- Trial name
- NCT07131852
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Borderline Personality Disorder
Outcomes of Mentalization-Based Treatment for Borderline Personality Disorder
The effects of a psychological treatment, Mentalization-Based Treatment, was studied using a research protocol with patients with mood swings and impulsive behavior (borderline personality disorder).
- Trial name
- NCT03295838
- Testing
- Mentalization-based treatment
- Volunteers
- 75 people
- Sponsor
- Karolinska Institutet
Tobacco Use Disorder
A Pilot Study of the Neural Correlates of Treatment Effect on Nicotine Craving
The purpose of this study is to gather pilot data to determine feasibility of and guide the development of a larger clinical trial investigating the effects of topiramate as an adjunct to nicotine replacement therapy and…
- Trial name
- NCT00208858
- Testing
- Topiramate
- Where
- United States
- Sponsor
- Emory University
Nicotine Dependence
Brain Activity and Smoking Cessation
In the current study, the investigators propose to test: (1) whether brain activation and connectivity in a resting state, assessed by ASL perfusion MRI, BOLD fMRI, and diffusion tensor imaging (DTI) predicts smoking relapse, and…
- Trial name
- NCT01186055
- Testing
- Smoking Cessation Counseling
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Gambling
Brief Therapies for Problem Gambling Substance Abusers
This project evaluates the efficacy of brief interventions for individuals seeking treatment for substance use disorders who also have gambling problems.
- Trial name
- NCT00685048
- Testing
- 10 minutes of psycho-education, 10 minutes of brief advice, four 50-minute individual therapy sessions of MET & CBT
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- UConn Health
Autism Spectrum Disorder
A Pilot Study of Microbiome in Patients With Autism Spectrum Disorder and Their Unaffected Siblings
The primary aims are to identify important gut microbiota signatures for youth with ASD, to identify dysbiosis features for different levels of ASD features and clinical courses, to search the possibility to intervene the disease…
- Trial name
- NCT05038748
- Testing
- Psychiatric diagnosis, ASD diagnosis
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
Diabetic Polyneuropathy, Sleep Hygiene
The Effect of Sleep Hygiene Education on Sleep Quality and Quality of Life in Patients With Painful Diabetic Polyneuropathy
This randomized controlled study was designed to the effect of sleep hygiene education on sleep quality and quality of life in patients with painful diabetic polyneuropathy The study was conducted between January 2025 and January…
- Conditions
- Diabetic Polyneuropathy, Sleep Hygiene, Pain
- Trial name
- NCT07646743
- Testing
- sleep hygiene education, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Trakya University
Depression, Involutional, Major Depresssion
Rapid Antidepressant Effects of Yohimbine in Major Depression
This study examines if Yohimbine, when given during the sleep cycle, will improve symptoms of depression within a matter of hours.
- Trial name
- NCT00078715
- Testing
- Yohimbine hydrochloride
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- National Institute of Mental Health (NIMH)
Depression, Anxiety
Mental Health Impact of the COVID-19 Pandemic on Amish and Mennonite Participants in AMBiGen
People have had to make a lot of changes to their lives due to the COVID-19 health crisis. Most experts agree that social distancing and other safety measures have taken a toll on people s mental health.
- Conditions
- Depression, Anxiety, Bipolar Disorder
- Trial name
- NCT04684615
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Cancer, Cognitive Impairment
Cancer and Mild Cognitive Impairment a Patient-Caregiver Behavioral Intervention
The purpose of this study is to see whether programs that include both a patient and their spouse or a patient and family caregiver (known as a dyad) are helpful for families in which one member of the dyad has cancer and mild…
- Trial name
- NCT04826315
- Testing
- COPE +
- Where
- United States
- Sponsor
- Duke University
Postoperative Cognitive Dysfunction
Assessment of POCD After Steep Trendelenburg Position and CO2 Pneumoperitoneum With Cerebral Oxygen
Postoperative cognitive decline (POCD) is a common and impactful outcome of surgical procedures in older adults. The pathophysiology and causative mechanisms for POCD are poorly understood.
- Trial name
- NCT03372135
- Where
- China
- Volunteers
- 147 people
- Sponsor
- RenJi Hospital
Obsessive - Compulsive Disorder
Neural Mechanisms of the Sensorymotor Circuit in Sensory Phenomena in OCD
The goal of this clinical study is to investigate the neural mechanisms of abnormal sensory phenomena in patients with Obsessive-Compulsive Disorder and to evaluate whether modulation of the insula-supplementary motor area…
- Trial name
- NCT07480408
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Meditation, Cognitive Reappraisal
Transforming Adolescent Perception and Mental Health Through Meditation and Cognitive Reappraisal A Mixed Method Study
This study will evaluate how a comprehensive meditation-based program, Inner Engineering, supports teens ages 15-18 in becoming more joyful, focused, resilient, and better equipped to manage stress and thrive.
- Conditions
- Meditation, Cognitive Reappraisal, Emotional Regulation
- Trial name
- THRIVE (NCT07173608)
- Testing
- Inner Engineering Program
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
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