Clinical trials: Mental
Autism Spectrum Disorder
Early Socioemotional Intervention for Children With Autism Spectrum Disorder in Hong Kong and Mainland China
This study aims to develop a culturally-sensitive parent-training intervention to enhance socioemotional functioning of young children (aged 3-6) with Autism Spectrum Disorder (ASD) in Mainland China.
- Trial name
- NCT04658043
- Testing
- Intervention on socioemotional functioning
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 1,000 people
- Sponsor
- The University of Hong Kong
Diabetes Mellitus, Type 2
Progressive Relaxation Exercise on Sleep Quality in Patients With Type 2 Diabetes
The purpose of this study is to evaluate the effect of progressive relief exercise on sleep quality in patients with type 2 diabetes.
- Trial name
- NCT05956743
- Testing
- progressive relaxation exercise sessions
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Mersin University
Post Partum Depression
Effectiveness of Thinking Healthy Program for Prevention of Antenatal Depression
The trial is to evaluate the effect of an evidence-informed, depression focused early prenatal prevention intervention at six weeks' postpartum.
- Trial name
- PAD (NCT04663243)
- Testing
- Thinking healthy Program sessions designed for antenatal period
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of the Punjab
PTSD
Efficacy of Cervical Sympathetic Blocks for PTSD
Millions of people suffer from anxiety disorders, including posttraumatic stress disorder (PTSD)-a condition that can profoundly disrupt daily life.
- Trial name
- NCT07087015
- Testing
- Cervical sympathetic nerve block, Ropivacaine, Normal Saline
- Volunteers
- 20 people
- Sponsor
- Stanford University
Emotional Distress, Burnout, Professional
A Self-directed Mobile Mindfulness Intervention to Address Distress and Burnout in Frontline Healthcare Workers
This is a pilot randomized waitlist control trial assessing if the feasibility of using a mobile mindfulness app to treat emotional distress and burnout amongst nurses taking care of COVID-19 patients.
- Conditions
- Emotional Distress, Burnout, Professional, Stress, Job, Anxiety
- Trial name
- LIFT-HCW (NCT04816708)
- Testing
- LIFT Mindfulness
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Duke University
Gender Dysphoria
Gender Identity and Own Body Perception
This study will provide valuable information on the neurobiological underpinning of gender dysphoria (GD) and the effects of sex hormones, and promises to uncover functional or structural neural patterns that could predict…
- Trial name
- NCT04374708
- Testing
- fMRI
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Cognitive Change
Effect of a Fermented Dairy Food With Probiotics on Mental Performance
Single-center, randomized, double-blind, placebo-controlled clinical study with two study groups. One group will consume a product with functional ingredients and the other group will consume a placebo product.
- Trial name
- ShotRM (NCT05323825)
- Testing
- Probiotic
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Bipolar Disorder (BD), Bipolar Disorder NOS
Child Bipolar Network Ketogenic Diet Approach to Bipolar Disorder in Adolescents
The present study is an open trial of ketogenic diets for adolescents and young adults (ages 12-21 yrs) in the depressive or mixed phases of bipolar disorder (BD).
- Conditions
- Bipolar Disorder (BD), Bipolar Disorder NOS, Bipolar Disorder I or II, Bipolar Spectrum Disorder
- Trial name
- CBN Keto (NCT06920940)
- Testing
- Ketogenic Therapy
- Where
- 4 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of California, Los Angeles
Post-Traumatic Stress Disorder
Cognitive and Emotional Factors in Visual Exploration Among Patients With Post-Traumatic Stress Disorder (SAILLANCE2)
Post-traumatic stress disorder (PTSD) is characterized by hypervigilance. In particular, previous works suggest that patients tend to scan constantly the environment for possible threats.
- Trial name
- SAILLANCE2 (NCT03519789)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Lille
Type 2 Diabetic Patients, Erectile Dysfunction
Prevalence and Risk Factors of Erectile Dysfunction in Type 2 Diabetic Patients
The investigators evaluated 250 male, type 2 diabetic patients, aged 18-80 years. They will undergo IIEF (International Index of Erectile Function), SAS of Zung (self-rating anxiety state)and SDS of Zung (self-rating depression…
- Trial name
- NCT01049750
- Testing
- type 2 diabetic patients
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- University of Pavia
Traumatic Brain Injury, Depression
Life Improvement Following Traumatic Brain Injury
The purpose of this study is to test the effectiveness of a telephone-based and in-person Cognitive Behavioral Therapy (CBT) intervention for treating Major Depressive Disorder (MDD) following Traumatic Brain Injury.
- Trial name
- LIFT (NCT00878150)
- Testing
- In-person Cognitive Behavioral Therapy, Telephone Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Bipolar Disorder, Dyssomnias
Sleep Disturbance and Bipolar Disorder
The study aims to evaluate a psychological intervention for individuals who suffer from sleep disturbance and bipolar disorder. We are hoping that this treatment will: (1) improve the quality of life of individuals with bipolar…
- Trial name
- NCT00993850
- Testing
- Cognitive behavioral therapy for insomnia, Bipolar education
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of California, Berkeley
Cocaine Dependence
Effectiveness of N-Acetylcysteine (NAC) in Treating Cocaine Dependent Individuals - 1
Currently, no effective drug treatment exists for cocaine dependence. Glutamate levels are disrupted with long-term cocaine use.
- Trial name
- NAC (NCT00218491)
- Testing
- N-Acetylcysteine
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- Medical University of South Carolina
Tobacco Use, Smoking Cessation
Ketamine and Motivational Enhancement Therapy for the Treatment of Tobacco Use Disorder
The purpose of the study is to examine whether an investigational medication called ketamine is able to improve treatment outcomes for tobacco use disorder when delivered in conjunction with brief motivational enhancement…
- Conditions
- Tobacco Use, Smoking Cessation, Nicotine Dependence
- Trial name
- NCT05796791
- Testing
- Ketamine Hydrochloride, Motivational enhancement therapy
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Pediatric Acute-Onset Neuropsychiatric Syndrome, Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections
A Study to Evaluate the Benefit of Octagam 5%® in Subjects With Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)
This study will evaluate the use of intravenous immunoglobulins (IVIG) at a dose of 1g/Kg/body weight given every three weeks for 6 infusions in pediatric subjects ages 4 - 16 years with moderate to severe PANS.
- Trial name
- PANS (NCT03348618)
- Testing
- IVIG
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- IMMUNOe Research Centers
Substance Abuse
Increasing Caregiver Engagement in Juvenile Drug Courts
The purpose of this study is to test a prize-based contingency management intervention for increasing caregiver engagement in juvenile drug court and adolescent drug treatment, and for achieving the ultimate outcomes of reduced…
- Trial name
- NCT03051997
- Testing
- Caregiver Contingency Management + Usual Drug Court Treatment, Usual Drug Court Treatment
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Medical University of South Carolina
Schizophrenia, Schizoaffective Disorder
Virtual Reality Job Interview Training in Severe Mental Illness
This is a randomized controlled trial to evaluate the community-based effectiveness of virtual reality job interview training (VR-JIT). Northwestern University is partnering with Thresholds Inc.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Depressive Disorder
- Trial name
- NCT03049813
- Testing
- Virtual Reality Job Interview Training, Supported Employment (Services as Usual)
- Where
- 4 sites in United States
- Volunteers
- 168 people
- Sponsor
- University of Michigan
Alzheimer Disease
Evaluation of [123I] MNI-330 and SPECT as a Marker of Beta-amyloid Protein Deposition
The main objectives of this proposal are as follows: To assess the dynamic uptake and washout of 123-I MNI-330, a potential imaging biomarker for β-amyloid burden in brain, using single photon emission computed tomography (SPECT)…
- Trial name
- NCT00657813
- Testing
- MNI-330 as a brain SPECT tracer of Beta-Amyloid
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Institute for Neurodegenerative Disorders
Postmenopausal Period, Fatigue
The Effect of Progressive Relaxation Exercises on Sleep Quality and Fatigue in Postmenopausal Period
The population of the study will be postmenopausal women who applied to the KETEM unit of a hospital in western Turkey for examination. This study is a two-group randomized controlled study.
- Conditions
- Postmenopausal Period, Fatigue, Sleep Quality
- Trial name
- NCT05483413
- Testing
- progressive relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Neurodegenerative Diseases, Cognition Disorders in Old Age
Probiotics in Mild Alzheimer's Disease
The main objective is to investigate whether administration of probiotics to patients with mild Alzheimer's Disease (AD) reduces neuroinflammation, improves cognitive function and modifies neurophysiological measures, compared to…
- Trial name
- NCT06181513
- Testing
- Probiotic Blend Capsule
- Where
- Cyprus
- Volunteers
- 40 people
- Sponsor
- University of Nicosia
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