Clinical trials: Mental
Stroke, Cognitive Decline
Efficacy and Safety of Immersive Virtual Reality for Post-stroke Cognitive Impairment
This is a single-blind randomized controlled trial to evaluate the efficacy and safety of immersive virtual reality for post-stroke cognitive impairment.
- Trial name
- EVRPSC (NCT06704360)
- Testing
- immersive VR pathfinding training, Occupational therapy
- Volunteers
- 40 people
- Sponsor
- Dingqun Bai
Obsessive Compulsive Disorder
Efficacy of Agomelatine in Patients With Obsessive-Compulsive Disorder
The study will evaluate the efficacy of agomelatine compared to placebo on the reduction of Obsessive and Compulsive symptoms after 16 weeks of treatment.
- Trial name
- NCT01108393
- Testing
- Agomelatine A
- Where
- Israel
- Volunteers
- 74 people
- Sponsor
- Institut de Recherches Internationales Servier
Marijuana Dependence
Hormones and Reduction in Co-users of Marijuana and Nicotine
The purpose of this study is to examine the role of progesterone (a naturally occurring hormone found in both men and women) on reducing marijuana use.
- Trial name
- NCT02579421
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Psychotic Disorders
Antipsychotic to Treat Psychosis Syndrome
This study assess the safety and effects of atypical antipsychotics in subjects with psychosis syndrome and psychosis risk syndrome.
- Trial name
- NCT02137616
- Testing
- risperidone, olanzapine, Quetiapine
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Central South University
Psychosis, Schizophrenia Spectrum Disorders
A Case Series of Culturally-adapted CBTp for Black People in the UK
The goal of this case series study is to learn if culturally-adapted cognitive-behavioural therapy is practical, acceptable and safe among Black Sub-Saharan African and Caribbean people experiencing psychosis.
- Trial name
- NCT07252206
- Testing
- Culturally-adapted cognitive-behavioural therapy
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- University of Manchester
Psychotic Disorders, Acceptance and Commitment Therapy
Inpatient Group Acceptance and Commitment Therapy (ACT) for Psychosis Spectrum Disorder
The pilot study that will serve as the basis for the larger project - a multicenter randomized controlled single-blinded trial (RCT) will focus on testing the feasibility and efficacy of an inpatient group ACT treatment program…
- Conditions
- Psychotic Disorders, Acceptance and Commitment Therapy, Psychotherapy, Group, Inpatients
- Trial name
- ASPIRE (NCT06086184)
- Testing
- ACT group therapy
- Where
- Germany
- Volunteers
- 32 people
- Sponsor
- Vivantes Netzwerk für Gesundheit GmbH
End Stage Liver Disease, End Stage Renal Disease
Transplant and Addiction Project (TAP) - 1
The purpose of this study is to test a novel distance-based (telephone) intervention to help transplant candidates with current or recent substance abuse to stay "clean and sober" both prior and following transplant surgery.
- Conditions
- End Stage Liver Disease, End Stage Renal Disease, Substance-Related Disorders
- Trial name
- NCT00249652
- Testing
- TAP, TAU
- Where
- 3 sites in United States
- Volunteers
- 41 people
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Huntington Disease
An Exploratory Clinical Trial in Early Stage Huntington's Disease Patients With SEN0014196
The primary objective of this study is to provide biological samples from patients with Huntington's disease to allow characterisation of the pharmacological mechanism of action of SEN0014196.
- Trial name
- PADDINGTON (NCT01485952)
- Testing
- SEN0014196 (Low Dose), SEN0014196 (High Dose)
- Where
- Germany
- Volunteers
- 55 people
- Sponsor
- Siena Biotech S.p.A.
Marijuana Dependence
Treatment of Marijuana Withdrawal Syndrome Using Escitalopram and Cognitive-Behavior Therapy
Recent studies have established the reliability, validity and time course of the cannabis withdrawal syndrome. This study will investigate the effects of combined treatment of Escitalopram with cognitive-behavior therapy in…
- Trial name
- NCT00598052
- Testing
- Escitalopram
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Cognitive Function, Dementia
MIND Diet and Cognitive Function in Middle-aged and Older Adults
A 12-month cluster-randomized controlled trial designed to test the effect of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet education on the rate of cognitive change and several other secondary…
- Trial name
- NCT06417749
- Testing
- Control arm, Intervention arm
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Chronic Stroke, Cognitive Impairment
Home-based Computerized Cognitive Rehabilitation in Chronic Stage Stroke
This study evaluates the effectiveness of Guttmann NeuroPersonalTrainer (GNPT), a tele-rehabilitation platform developed as a tool for the cognitive rehabilitation of chronic stroke patients.
- Trial name
- CHRONIC (NCT03326349)
- Testing
- Guttmann, NeuroPersonalTrainer, Ictus.online
- Where
- Spain
- Volunteers
- 41 people
- Sponsor
- Josep M. Tormos Muñoz
SCHIZOPHRENIA 1 (Disorder)
Basal Stimulation Therapy in Adults With Schizophrenia Requiring Institutional Care
The aim of the study is to obtain knowledge of the impact of basal stimulation therapy on the health status of adults suffering from schizophrenia and requiring permanent institutional care.
- Trial name
- NCT07769749
- Testing
- physiotherapy, 2 x a week for 6 weeks, basal therapy, 2 x a week for 6 weeks, Standard therapy group
- Where
- 2 sites in Poland
- Volunteers
- 12 people
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Attention Deficit and Hyperactivity Disorder
Descriptive Epidemiology of a Specialized Consultation on ADHD in Adults at the Strasbourg University Hospital
The main objective of this study is to carry out a descriptive study of the clinical and demographic characteristics of patients having consulted for a specialized opinion about ADHD in adults of the psychiatric service of the…
- Trial name
- Stras-TDA (NCT03601858)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
Autism Spectrum Disorder (ASD
Experiences of Healthcare for Autistic TGD Adults
To explore the experiences of autistic gender diverse adults that have attempted or are attempting to access, have accessed or are currently accessing gender identity healthcare in the United Kingdom
- Trial name
- NCT06850948
- Testing
- Qualitative
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- University of Nottingham
Dementia, Alzheimer Disease
Play Intervention for Dementia for Promoting Cognitive Function: A Feasibility Study
This study intends to use Play Intervention for Dementia (PID) to promote cognitive functions of people with early to moderate dementia.
- Trial name
- NCT02846415
- Testing
- Play Intervention for Dementia
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Psychoses, Affective Disorder
Patient-controlled Admissions in Inpatient Mental Health Services
Patient-controlled admissions are short self-referred inpatient admissions in mental health services without approval by clinicians. The intention is to reduce a high use of inpatient care.
- Trial name
- NCT03609515
- Testing
- Patient-controlled admission
- Volunteers
- 58 people
- Sponsor
- University Hospital, Akershus
Alcohol Use Disorder
Ibudilast for the Treatment of Alcohol Use Disorder
This study is a double-blind, placebo-controlled randomized clinical trial of Ibudilast (IBUD) (50mg twice a day) for the treatment of Alcohol Use Disorder (AUD).
- Trial name
- NCT03594435
- Testing
- Ibudilast
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder
Mindfulness for Parents of Children With Autism Spectrum Disorder Autism Spectrum Disorder
The current study examines the efficacy of Mindfulness-Based Stress Reduction (MBSR) to reduce parenting stress, lessen parental reactivity and negativity, and decrease child externalizing behaviors among families of children…
- Trial name
- ASD (NCT03459625)
- Testing
- Mindfulness-Based Stress Reduction (MSBR), Psychoeducational Support Group (PE)
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Loma Linda University
HIV, Insomnia
Effect of Dolutegravir Compared With Darunavir/Cobicistat on the Severity of Neuropsychiatric Effects al 12 Weeks in Antirretroviral Treatment-Naive Adults.
This clinical trial aimed at evaluating changes in neuropsychiatric scales for depression, anxiety, insomnia, and sleep quality in people living with HIV (PLHIV) who initiate antiretroviral therapy (ART) with a regimen of…
- Conditions
- HIV, Insomnia, Anxiety
- Trial name
- MORFEO (NCT06787976)
- Testing
- Dolutegravir (DTG), Darunavir/Cobicistat (FDC)
- Volunteers
- 140 people
- Sponsor
- Instituto Mexicano del Seguro Social
Borderline Personality Disorder
Treating Suicidal Behavior and Self-Mutilation in People With Borderline Personality Disorder
This study will determine whether dialectical behavior therapy and fluoxetine are more effective combined or alone in treating people with borderline personality disorder.
- Trial name
- NCT00533117
- Testing
- Fluoxetine, Dialectical Behavior Therapy, Supportive psychotherapy
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- New York State Psychiatric Institute
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