Clinical trials: Mental
Dementia, Hearing Loss
Validation of Cognitive Screenings for the Hearing Impaired
There are currently no cognitive tests that have been validated as screening tools for people with dementia and comorbid hearing loss.
- Conditions
- Dementia, Hearing Loss, Auditory Processing Disorder
- Trial name
- NCT03648502
- Testing
- Cognitive tests and hearing tests
- Where
- 2 sites in United Kingdom
- Volunteers
- 78 people
- Sponsor
- University College, London
Intellectual Disabilities (F70-F79)
North Health in Intellectual Disability
Intellectual disability (ID) is a diagnosis characterized by significant limitations both in intellectual functioning and in adaptive behavior as expressed in conceptual, social and practical adaptive skills.
- Trial name
- NOHID (NCT03889002)
- Where
- Norway
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Delirium Risk, Critical Illness in Coronary ICU Patients
THE EFFECTS OF VIRTUAL ART THERAPY ON PHYSIOLOGICAL PARAMETERS, DELIRIUM RISK, ANGER, ANXIETY, AND MENTAL AND SPIRITUAL RECOVERY IN INTENSIVE CARE PATIENTS.
Patients in intensive care units experience significant physiological and psychological stress due to life-threatening conditions and invasive treatments.
- Conditions
- Delirium Risk, Critical Illness in Coronary ICU Patients, Mental and Spiritual Recovery, Effects of Virtual Art Therapy
- Trial name
- NCT07562802
- Testing
- Virtual Art Therapy
- Volunteers
- 62 people
- Sponsor
- Inonu University
Endometriosis, Dyspareunia
Transvaginal Low-level Laser Therapy to Improve Pelvic Pain and Sexual Function in Patients with Endometriosis.
Dyspareunia is defined as pain with penetrative sexual intercourse. Women with endometriosis have a nine-fold increased risk of dyspareunia, when compared to the general female population.
- Conditions
- Endometriosis, Dyspareunia, Pelvic Pain
- Trial name
- NCT05540353
- Testing
- Transvaginal photobiomodulation
- Where
- 6 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Mild Cognitive Impairment (MCI), Mild Alzheimer Disease
iTBS in MCI and Mild AD
This study aims to examine the effects of iTBS on cognitive function in individuals with MCI or mild AD, with a secondary objective of exploring prefrontal TBS mechanisms for cognitive function and the effect of iTBS on BDNF.
- Trial name
- NCT06670820
- Testing
- Active rTMS
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Defense Medical Center, Taiwan
Substance Use Disorders, Substance Use
Examining Feasibility and Acceptability of Telemedicine for Substance Use Disorder (SUD)
The objective of this pilot intervention study is to iteratively refine motivational interviewing and psychosocial intervention programs delivered via telehealth (Teletx) to help improve substance use and other related outcomes…
- Conditions
- Substance Use Disorders, Substance Use, Substance Dependence
- Trial name
- NCT04768920
- Testing
- MI-CBT Teletx
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Vitamin D Deficiency, Neurocognitive Dysfunction
Vitamin D Supplementation and Neurocognition
This study will evaluate the effect of vitamin D supplementation on the neurocognitive function of older people with lower than normal levels of vitamin D at baseline
- Trial name
- Dcog (NCT03019120)
- Testing
- Vitamin D
- Where
- Israel
- Sponsor
- Rambam Health Care Campus
Affect, Alcohol Consumption
Automated Telephone Follow-up in the Swedish Prison and Probation Services
The purpose of this study is to investigate whether automated telephony may be used for daily assessments of paroled offenders, and whether a brief intervention based on these daily assessments may result in a more positive…
- Conditions
- Affect, Alcohol Consumption, Substance Abuse
- Trial name
- NCT01727882
- Testing
- Brief feedback, Daily assessments
- Where
- Sweden
- Volunteers
- 108 people
- Sponsor
- Region Skane
Attention Deficit Hyperactivity Disorder, Attention Deficit Disorder
Medication Integration in Treatment of Comorbid Adolescent Substance Users/Attention Deficit Hyperactivity Disorder
The goal of this project is to develop and test a brief protocol designed to systematically integrate pharmacological interventions for Attention Deficit Hyperactivity Disorder (ADHD) into behavioral treatment services for…
- Trial name
- MIP (NCT01369459)
- Testing
- MIP Protocol
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- The National Center on Addiction and Substance Abuse at Columbia University
Major Depressive Disorder
Study to Evaluate Treatment Effects Associated With the NeuroStar SoftStart Treatment Feature
The purpose of this study is to evaluate the comfort of the NeuroStar® Advanced Therapy System regular prescribed TMS protocol versus a New Feature.
- Trial name
- Comfort Start (NCT05535062)
- Testing
- repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Neuronetics
Tourette Syndrome, Tourette's Disorder
Remote Delivery of a Mindfulness-based Intervention for Tics
This research study is being done to compare a mindfulness-based intervention for tics (MBIT) to psychoeducation with relaxation and supportive therapy (PRST) for individuals with Tourette's syndrome or Persistent Tic Disorders…
- Conditions
- Tourette Syndrome, Tourette's Disorder, Chronic Motor Tic Disorder, Chronic Vocal Tic Disorder
- Trial name
- MBIT (NCT06408662)
- Testing
- mindfulness-based intervention for tics (MBIT), psychoeducation with relaxation and supportive therapy (PRST)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Johns Hopkins University
Cocaine-Related Disorders, Drug Administration Schedule
Evaluation of Modafinil as a Cocaine Treatment Medication and Interactions With Cocaine - 1
The purpose of this study is to evaluate modafinil, a cocaine treatment medication, and its interactions with intravenous (IV) cocaine.
- Conditions
- Cocaine-Related Disorders, Drug Administration Schedule, Infusions, Intravenous
- Trial name
- NCT00033046
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Autism Spectrum Disorder (ASD), Autism
Xenon Therapy for Children With Autism Spectrum Disorder
This study aims to evaluate the efficacy and safety of inhaled xenon for the treatment of children with autism spectrum disorder (ASD).
- Trial name
- ASD; Xe (NCT07435103)
- Testing
- Xenon
- Where
- China
- Volunteers
- 72 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Low Libido
Hypoactive Sexual Desire Disorder in Males
The purpose of this study is to determine if the study drug will increase sexual desire in men with HSDD. Half of the participants will take ADDYI while the other half will receive a placebo (a look-alike pill with no medicine).
- Trial name
- HSDD (NCT04002661)
- Testing
- Flibanserin
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Mohit Khera
Brain Neoplasms, Malignant, Brain Neoplasms, Benign
Pioglitazone Hydrochloride in Preventing Radiation-Induced Cognitive Dysfunction in Treating Patients With Brain Tumors
RATIONALE: Pioglitazone hydrochloride may be effective treatment for cognitive dysfunction caused by radiation therapy. PURPOSE: This phase I trial is studying the side effects and best dose of pioglitazone hydrochloride in…
- Conditions
- Brain Neoplasms, Malignant, Brain Neoplasms, Benign, Malignant Meningioma, Glioblastoma Multiforme
- Trial name
- NCT01151670
- Testing
- pioglitazone
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Wake Forest University Health Sciences
Cannabis, Youth Drinking
Development and Evaluation of HighAlert
In Canada, youth ages 16-24 have the highest rates of cannabis use, impaired driving, and express the least concern for driving under the influence of cannabis (DUIC).
- Trial name
- NCT06098573
- Testing
- High Alert, Information condition, No contact
- Where
- Canada
- Volunteers
- 103 people
- Sponsor
- Western University, Canada
Knee Osteoarthritis
Effect of an Information- and Self-management App for People With Knee Osteoarthritis
The primary aim of the trial is to assess if an information- and self-management app provided in the period between referral and consultation in specialist healthcare can improve knowledge about osteoarthritis and decision…
- Trial name
- OA-AID (NCT07603973)
- Testing
- Information- and self-management app, Control
- Where
- Norway
- Volunteers
- 204 people
- Sponsor
- Diakonhjemmet Hospital
Dementia Alzheimers, Dementia
Detecting Dementia in the Retina Using Optical Coherence Tomography
This retrospective case control explores the retinal features of dementia associated with neurodegenerative diseases, particularly Alzheimer's disease.
- Conditions
- Dementia Alzheimers, Dementia, Dementia, Vascular, Dementia Senile
- Trial name
- NCT03631069
- Where
- United Kingdom
- Volunteers
- 280,000 people, healthy volunteers welcome
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Brain Injuries, Sleep Disturbance
Music Listening and Sleep in Rehabilitation of People With Acquired Brain Injury
An Injury to the brain may lead to sleep-wake disturbances which may negatively influence functional recovery, quality of life and general rehabilitation.
- Trial name
- NCT05620069
- Testing
- Music listening
- Where
- Denmark
- Volunteers
- 5 people
- Sponsor
- Vejlefjord Rehabilitation
Anhedonia, Anxiety
Ecological Momentary Intervention for Reward in Anhedonia
The present study evaluates a two week ecological momentary intervention (EMI) in reducing anhedonia and psychological distress (i.e. elevated depression, stress and anxiety).
- Conditions
- Anhedonia, Anxiety, Stress, Depression
- Trial name
- EMIRA (NCT07155941)
- Testing
- Training of reward processing/sensitivity, Relaxation Training (PMR), Psychoeducation
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Philipps University Marburg
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