Clinical trials: Mental
Substance Use Disorders
Preconception Intervention for Incarcerated Women With Substance Use
The goal of this pilot trial is to test the feasibility and acceptability as well as efficacy of the adapted intervention, CHOICES-PLEAS (Pregnancy Liberated from Exposure to Alcohol and Substances) among women will illicit…
- Trial name
- NCT05854836
- Testing
- CHOICES-PLEAS (Pregnancy Liberated from Exposure to Alcohol and Substances)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- St. Louis University
Anxiety Disorders
Attention Bias Modification Treatment (ABMT) for Anxiety Disorders in Youth
Attention biases in threat processing have been assigned a prominent role in the etiology and maintenance of anxiety disorders. Attention Bias Modification Treatment (ABMT) utilizes computer-based protocols to implicitly modify…
- Trial name
- NCT02460536
- Testing
- Attention Bias Modification treatment (ABMT), Exposure only +ABMT, Attention training only +ABMT
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel Aviv University
HIV Infections, Alcohol Dependence
Cell Phone Technology Targeting ART and Naltrexone Adherence and Alcohol Use
The proposed study, for HIV positive alcohol dependent adults currently taking naltrexone, is a pilot randomized controlled trial (RCT) examining the outcomes of a 12-week behavioral support program delivered via text-messaging.
- Trial name
- ALCTXT (NCT02603471)
- Testing
- Informational group, Text Messaging CBT (TXT-CBT)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of California, Los Angeles
Personality Disorder, Borderline, Avoidant Personality Disorder
Effectiveness of Group Based Schema Therapy in the Treatment of Personality Disorders
This study intends to compare the effectiveness of schema therapy with standard psychiatric outpatient care for patients with borderline or avoidant personality disorder.
- Trial name
- NCT00247234
- Testing
- Schema Therapy, standard care
- Where
- Norway
- Volunteers
- 90 people
- Sponsor
- Norwegian University of Science and Technology
Attention Deficit Disorder With Hyperactivity
Safety and Efficacy of SPD503 in Treating Attention-Deficit/Hyperactivity Disorder (ADHD) in Children Aged 6-17
The purpose of this study is to assess the safety and efficacy of SPD503 (Guanfacine hydrochloride) compared to placebo in the treatment of ADHD in children and adolescents aged 6-17
- Trial name
- NCT00152009
- Testing
- SPD503 (Guanfacine hydrochloride) (2 mg), SPD503 (3 mg), SPD503 (4 mg)
- Volunteers
- 345 people
- Sponsor
- Shire
Lewy Body Disease, Alzheimer Disease
A Study of Neurodegeneration and Neuronal Fluctuations in Lewy Body Disease and Alzheimer's Disease
The purpose of this research study is to investigate how the brain, memory, thinking, and motor behavior change both in individuals with movement and/or cognitive disorders, as well as healthy individuals.
- Conditions
- Lewy Body Disease, Alzheimer Disease, Healthy
- Trial name
- NCT06057909
- Testing
- Magnetic Resonance Imaging, Electroencephalography, Electromyography
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Alcohol Abuse, Anxiety
Mobile App for Latinx Hazardous Drinkers With Clinical Anxiety
The purpose of this study is to develop and examine a culturally adapted, brief, integrated, Spanish language mobile health application for the Android platform, optimized to deliver a personalized feedback intervention (PFI)…
- Trial name
- NCT05288699
- Testing
- Aliento
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Michael J. Zvolensky, Ph.D.
Alzheimer's Disease, Dementia
Optimizing Dementia Care
The purpose of this randomized controlled pilot study is to examine the preliminary effectiveness, feasibility, and potential treatment moderators (i.e., behavioral symptoms and spousal relationship status) of a newly developed…
- Conditions
- Alzheimer's Disease, Dementia, Dementia, Vascular, Caregivers
- Trial name
- ODeC (NCT02585232)
- Testing
- Counseling (C), Care Consultation (CC)
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- VA Office of Research and Development
Delirium, Hypoxia
Nocturnal Hypoxia in Geriatric Patients After Hip Fracture
Delirium is a common complication following hip fracture surgery (HFS) in older people. Postoperative hypoxia has also been associated with delirium, but not specifically in geriatric patients.
- Trial name
- HIPOX (NCT04007432)
- Testing
- pulse oxymeter
- Where
- 2 sites in France
- Volunteers
- 70 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bipolar Disorder
Effectiveness of Family-Focused Treatment Plus Pharmacotherapy for Bipolar Disorder in Adolescents
This study will evaluate the effectiveness of family-focused treatment (FFT) plus pharmacotherapy in treating adolescents with bipolar disorder.
- Trial name
- NCT00332098
- Testing
- Family-Focused Treatment Plus Pharmacotherapy, Enhanced Care Plus Pharmacotherapy
- Where
- 3 sites in United States
- Volunteers
- 145 people
- Sponsor
- University of California, Los Angeles
Depression, Bipolar Disorder
Minocycline and Celecoxib as Adjunctive Treatments of Bipolar Depression
Bipolar disorder is a leading cause of disability worldwide. A high proportion of patients with bipolar disorder experience persistent depressive symptoms that do not respond to standard drug treatments.
- Conditions
- Depression, Bipolar Disorder, Bipolar Depression, Mood Disorders
- Trial name
- NCT02703363
- Testing
- Minocycline, Celecoxib
- Where
- 4 sites in Pakistan
- Volunteers
- 265 people
- Sponsor
- Pakistan Institute of Living and Learning
Acupuncture, ADHD - Attention Deficit Disorder With Hyperactivity
Acupuncture for ADHD: Acupoint Data Mining, Clinical Effectiveness, and Interviews to Explore Treatment Outcomes.
This study aims to evaluate the efficacy of acupuncture as a treatment for Attention Deficit Hyperactivity Disorder (ADHD) in children aged 6-12 years.
- Conditions
- Acupuncture, ADHD - Attention Deficit Disorder With Hyperactivity, Children, Interview
- Trial name
- ACU-ADHD (NCT06860763)
- Testing
- Chinese herbal medicine, Acupuncture
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The Third Affiliated Hospital of Beijing University of Chinese Medicine
Erectile Dysfunction, Overactive Bladder
Mirabegron For Erectile Dysfunction
The only class of oral erectile dysfunction (ED) medication on the market are the phosphodiesterase Type 5 inhibitors (PDE5i). This pilot study is being done to evaluate the effect of Mirabegron, an oral beta-3 adrenergic…
- Conditions
- Erectile Dysfunction, Overactive Bladder, Urinary Incontinence
- Trial name
- NCT02916693
- Testing
- Mirabegron
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Parenting Capacities of Substance Abusing Mothers
Trial of Mentalization-Based Therapy for Substance Using Mothers of Infants and Toddlers
A formal randomized efficacy trial testing the Mothers and Toddlers' program, an attachment-based parenting intervention for mothers enrolled in addiction treatment and caring for young children.
- Trial name
- NCT01240993
- Testing
- Mothers and Toddlers Program, Parent Education
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Yale University
Burnout, Professional, Mental Health Issue
Ambulatory Electrodermal Activity Measurements as Part of Identification and Prevention of Job Burnout
The study investigates the associations of ambulatory electrodermal activity (EDA) measurements with mental well-being at work, especially job burnout.
- Conditions
- Burnout, Professional, Mental Health Issue, Anxiety, Depression
- Trial name
- NCT05317793
- Where
- 3 sites in Finland
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Schizophrenia
Joint Crisis Plan Effectiveness in Preventing Relapses in Schizophrenia and Schizoaffective Disorder
The Joint Crisis Plan = SOS Plan is a reference to a particular form of psychiatric advance directive which involves the patient, the healthcare team, their relatives and a third party caregiver as intermediary for the project.
- Trial name
- SOS (NCT02627716)
- Testing
- SOS Plan
- Where
- 4 sites in France
- Volunteers
- 124 people
- Sponsor
- University Hospital, Lille
Insomnia, Insomnia Chronic
Sleep Difficulties After Loss: Exploring the Beneficial Effect of Brief Behavioral Therapy for Insomnia in a Sample of Bereaved Individuals
The goal of the study is to investigate whether a brief behavioral therapy for insomnia (BBTI) improves sleep in bereaved patients screened for insomnia compared to an active control group (sleep hygiene education).
- Conditions
- Insomnia, Insomnia Chronic, Complicated Grief
- Trial name
- SLEEPLOSS (NCT07167706)
- Testing
- Brief Behavioral Therapy for Insomnia, Sleep Hygiene Therapy
- Where
- Denmark
- Volunteers
- 58 people
- Sponsor
- University of Aarhus
Behavior Problems
Mental Health Services for Toddlers in Foster Care
Toddlers (2- to 3-year-old children) in foster care often have difficulty regulating behavior and biology, and are at risk for a host of mental health problems.
- Trial name
- NCT01261806
- Testing
- Attachment and Biobehavioral Catch-up, Developmental Education for Families
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Healthy
A Study to Assess Effects of Clarithromycin on Pharmacokinetics of JNJ-54861911 in Healthy Male Participants
The purpose of this study is to assess the effects of strong cytochrome P450 (CYP) 3A4 inhibitors (Itraconazole and Clarithromycin), on pharmacokinetics (PK) (study of the way a drug enters and leaves the blood and tissues over…
- Trial name
- NCT02197884
- Testing
- JNJ-54861911, 25 mg, Itraconazole 200 mg, Clarithromycin 500 mg
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Schizophrenia and Disorders With Psychotic Features, Psychotic Episode
Effectiveness of a Mindfulness-based Group Training Addressing Social Cognition in First Episode Psychosis (AGES-Mind)
The current investigation aims to compare two group intervention in patients with a first episode of psychosis, that is, people who have suffered their first psychotic episode within 5 years prior to their inclusion in the study.
- Trial name
- AGES-Mind (NCT03309475)
- Testing
- SocialMIND, Psychoeducational multicomponent intervention, Psychosocial treatment
- Where
- Spain
- Volunteers
- 59 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
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