Clinical trials: Mental
Mental Health Disorder, Obesity
Improving Mental Health in Youth and Lowering Risk for Obesity Through a Digital Preventative Product
The goal of this study is to test the feasibility and utilization of a redesigned mobile app and health coaching platform (Vira) in youth (aged 18-25 years) with elevated depressive symptoms who are overweight/obese and/or…
- Conditions
- Mental Health Disorder, Obesity, Overweight
- Trial name
- NCT05638516
- Testing
- Vira mobile app intervention, Vira mobile app intervention + coaching
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Ksana Health
Cancer, Cognitive Impairment
Cancer and Mild Cognitive Impairment Dyadic Intervention
The purpose of this study is to see whether programs that include both a patient and their spouse or a patient and family caregiver (known as a dyad) are helpful for families in which one member of the dyad has cancer and mild…
- Trial name
- NCT05144516
- Testing
- Behavioral: COPE +
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Duke University
Alzheimer's Disease
A Study to Test the Efficacy, Safety, and Tolerability of Bepranemab (UCB0107) in Patients With Mild Cognitive Impairment or Mild Alzheimer's Disease (AD)
The purpose of the study is to investigate the effect of bepranemab versus (vs) placebo on the Clinical Dementia Rating Scale Sum of Boxes (CDR-SB) up to Week 80 in study participants with prodromal or mild Alzheimer's Disease…
- Trial name
- NCT04867616
- Testing
- Bepranemab
- Where
- 103 sites in United States, Belgium and 8 more
- Volunteers
- 466 people
- Sponsor
- UCB Biopharma SRL
Alzheimer's Disease
A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease
This is a multicentre, randomized, double-blind, placebo-controlled, parallel group Phase II study to evaluate the efficacy and safety of VHB937 in participants with early AD followed by an Extension.
- Trial name
- NCT07094516
- Testing
- VHB937
- Where
- 73 sites in United States, Australia and 13 more
- Volunteers
- 97 people
- Sponsor
- Novartis Pharmaceuticals
Intellectual Disability
Physical Activity, mHealth and Intellectual Disability - a Pilot Study
The main objective of this pilot study is to assess distant procedures, study experiences and feasibility of a planned randomized controlled trial investigating the use of a mHealth support tool on physical activity for…
- Trial name
- NCT04929106
- Testing
- mHealth support tool
- Where
- Norway
- Volunteers
- 9 people
- Sponsor
- University Hospital of North Norway
Attention Deficit/Hyperactivity Disorder
An SMS Intervention to Improve Adherence to Stimulant Medications in Adults With ADHD
This study will assess the efficacy of the text messaging (SMS-based) disease management intervention to improve adherence to stimulants in adults with Attention Deficit/Hyperactivity Disorder (ADHD).
- Trial name
- NCT04189536
- Testing
- SMS Intervention
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Massachusetts General Hospital
Depression During Pregnancy
Virtual Reality-enhanced Psychotherapy for Perinatal Depression
Perinatal depression is a growing public health crisis in the United States, affecting one in five individuals during pregnancy or postpartum.
- Trial name
- NCT07279311
- Testing
- Virtual reality behavioral activation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Stanford University
Dyslexia
Dopaminergic Enhancement of Learning and Memory in Healthy Adults and Patients With Dyslexia
This study aims to determine whether levodopa, in combination with a high frequency training of (grammatical) rules, is effective in boosting learning success in healthy subjects and whether this kind of training in combination…
- Trial name
- NCT00111371
- Testing
- Levodopa
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Major Depressive Disorder
Biomarkers of Social Sensitivity in Major Depression
Major depression disorder (MDD) is a frequent and disabling mental disorder with great risk of recurrence and chronicity. Interpersonal factors are among the strongest predictors of the course and duration of an episode of…
- Trial name
- SENSO (NCT02214511)
- Testing
- emotional facial stimuli, Cyberball game
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Grief
A Grief Support App for Adults Experiencing Bereavement
Losing a loved one is a difficult experience. Some people may require psychological support, but even for those who do not, grief can often feel overwhelming.
- Trial name
- NCT07862244
- Testing
- Self-guided grief app (Daybreak), Waiting list
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Medical Research Council Cognition and Brain Sciences Unit
Cardiac Arrest, Neurologic Dysfunction
Identification of Neuroprognostic Factors for Out-of-hospital Cardiopulmonary Arrest (MIRA29)
From the informatized prehospital care registry, data will be collected anonymously for all patients' requiring cardiopulmonary resuscitation for an out-of-hospital cardiac arrest within the Norther Finistere sanitary region.
- Conditions
- Cardiac Arrest, Neurologic Dysfunction, Cognitive Impairment
- Trial name
- MIRA29 (NCT06569134)
- Where
- 2 sites in France
- Volunteers
- 1,200 people
- Sponsor
- University Hospital, Brest
Schizophrenia
Oxytocin Add on Study for Stable Schizophrenic Patients
The objective of the study is to compare the efficacy of intranasal oxytocin versus intranasal placebo to improve symptoms in schizophrenia patients who have residual symptoms despite being on adequate treatment with…
- Trial name
- Oxytocin (NCT00506909)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- David Feifel
Major Depressive Disorder
The Safety and Efficacy of Psilocybin in Cancer Patients With Major Depressive Disorder
This is a Phase II, single-center, fixed dose, open label trial to explore the safety, tolerability and efficacy of a 25mg dose of psilocybin in cancer patients with MDD.
- Trial name
- NCT04593563
- Testing
- Psilocybin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Maryland Oncology Hematology, PA
Adolescent Well-Being, Mental Health Wellness
Predict the Best Level of Care Placement for Each Child's Behavioral Health Needs - Effectiveness Study
The purpose of this study is to test the effectiveness of a new clinical decision support tool, Placement Success Predictor (PSP), in a naturalistic setting.
- Trial name
- NCT06834763
- Testing
- Clinical team access to Placement Success Predictor (PSP) results
- Where
- United States
- Volunteers
- 403 people
- Sponsor
- Outcome Referrals, Inc.
Attention Deficit Hyperactivity Disorder (ADHD)
Impact of Structured Exercise Programs on Cognitive, Motor and Behavioral Outcomes in Children With ADHD
The purpose of this study is to investigate the effects of structured exercise interventions (Gince Zumba and Square Stepping) on cognitive, motor and behavioral functions of children diagnosed with Attention Deficit…
- Trial name
- ADHD (NCT07376863)
- Testing
- Gince Zumba Exercise, Square Stepping Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Cukurova University
Perinatal Depression, Affective Disorder
Validation of the French Version of the Perinatal Assessment of Paternal Affectivity (PAPA)
The transition to parenthood is a critical period for both the woman and her partner, and this can affect the mental health of the parents.
- Conditions
- Perinatal Depression, Affective Disorder, Fathers
- Trial name
- French-Papa (NCT06594263)
- Where
- France
- Volunteers
- 343 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Posttraumatic Stress Disorder (PTSD)
MDMA-AT for PTSD in Young Adults With Childhood Trauma
This study is testing a new, emerging treatment for young adults (ages 18-26) with Posttraumatic Stress Disorder (PTSD). The treatment is combining the substance, MDMA, with up to three psychotherapy sessions, also known as…
- Trial name
- NCT07765693
- Testing
- MDMA assisted psychotherapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Jenna M. Traynor
Alzheimer Dementia (AD), Elderly
Therapy of Alzheimer's Disease With Neurofeedback
The project aims to investigate in patients of Alzheimer's disease in a prodromal state (early state of the disease) compared to healthy subjects whether neurofeedback training with functional MRI (fMRI) can improve cognitive…
- Trial name
- NCT03070821
- Testing
- rtfMRI neurofeedback training, 3T MRI
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Aachen
Stimulant Use, Substance Use Disorders
Enhancing Prospective Thinking in Early Recovery
The goal of this clinical trial is to use a novel virtual reality intervention to test for efficacy in reducing alcohol use and increasing abstinence, with concomitant increases in future self-identification, future time…
- Trial name
- NCT05835921
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Indiana University
Insomnia
A Pilot Study of Suvorexant for Insomnia in Parkinson Disease
The purpose of this study is to see if the study drug, suvorexant, is safe and effective in treating symptoms of insomnia in people with Parkinson's Disease.
- Trial name
- NCT02729714
- Testing
- Suvorexant
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Burdick, Daniel, M.D.
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