Clinical trials: Mental
Alcoholism, Alcohol Withdrawal
Preventing Alcohol Withdrawal With Oral Baclofen
The purpose of this study is determine if the medication baclofen can prevent the symptoms of Alcohol Withdrawal Syndrome (AWS) in hospitalized patients who may be at risk for AWS.
- Trial name
- BACLOFEN III (NCT01937364)
- Testing
- Baclofen
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Essentia Health
Nicotine Dependence
Targeting Orexin to Treat Nicotine Dependence
Tobacco smoking continues to be the primary cause of preventable mortality in the United States. Despite the availability of smoking cessation aids, the majority of those trying to quit smoking end up relapsing.
- Trial name
- NCT03999099
- Testing
- Suvorexant 20 mg, Suvorexant 10 mg
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Mclean Hospital
Chronic Insomnia
Evaluation of the Efficacy of E2R Hypnotherapy in the Management of Chronic Insomnia in Primary Care (HypERR)
In France, the treatment of chronic insomnia relies mainly on hypnotic drugs in routine care, despite the high level of iatrogenicity.
- Trial name
- HypERR (NCT06898099)
- Testing
- "Standard care" control group (without hypnosis), Experimental group: "E2R hypnosis"
- Where
- 35 sites in France
- Volunteers
- 136 people
- Sponsor
- Rennes University Hospital
Restless Legs Syndrome
Iron Sucrose In The Treatment of Restless Legs Syndrome: Safety of Three Dose Regimens as Evaluated by Clinical Assessments
Non-randomized open label Phase II clinical trial in which subjects meeting criteria for RLS were assigned to 1 of 3 treatment cohorts.
- Trial name
- NCT00895232
- Testing
- Cohort I, Cohort II, Cohort III
- Volunteers
- 21 people
- Sponsor
- American Regent, Inc.
Schizophrenia, Bipolar Disorder
The Role of Dysmyelination in Cognitive Impairment of Psychotic Spectrum Disorders
This is a single center study that uses both between-group comparisons and correlational analyses to establish biomarkers of dysmyelination and cognitive impairment in Psychotic Spectrum Disorders using imaging and…
- Trial name
- NCT03166098
- Testing
- Cognitive Function Assessments
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- NYU Langone Health
Major Depressive Disorder
A Study in the Treatment of Children and Adolescents With Major Depressive Disorder
The purpose of this study is to assess whether duloxetine is superior to placebo in the treatment of children and adolescents with major depressive disorder (MDD)
- Trial name
- NCT00849693
- Testing
- fluoxetine, duloxetine
- Where
- 56 sites in United States, Argentina and 2 more
- Volunteers
- 463 people
- Sponsor
- Eli Lilly and Company
Major Depressive Disorder, Recurrent
Mechanisms of Mindfulness-Based Cognitive Therapy in the Treatment of Recurrent Major Depressive Disorder
The primary purpose of this study is to investigate neural mechanisms and predictors of treatment outcome in Mindfulness-Based Cognitive Therapy (MBCT) for recurrent Major Depressive Disorder.
- Trial name
- NCT03353493
- Testing
- MBCT, TAU
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Diabetes, Depression
e-Pharmacovigilance II - Surveillance for Safety and Effectiveness - Calling for Earlier Detection of Adverse Reactions
Specific Aim 1: To develop a patient-reported, EHR-integrated system to actively monitor the safety and effectiveness of treatment for patients taking FDA-approved medications for one of four common chronic conditions (diabetes…
- Conditions
- Diabetes, Depression, Insomnia, Hypertension
- Trial name
- CEDAR (NCT02087293)
- Testing
- Intervention arm - automated call and phone-based pharmacist counseling
- Where
- United States
- Volunteers
- 38,400 people
- Sponsor
- Brigham and Women's Hospital
Attention-Deficit/Hyperactivity Disorder
Supplementation of Phosphatidylserine (PS) and n-3 Long Chain Fatty Acids (EPA, DHA) in Children With ADHD
To determine whether supplementation of omega-3 long-chain polyunsaturated fatty acid conjugated to phosphatidylserine rather than triglycerides (fish oil) could affect Attention-deficit/hyperactivity disorder symptoms in…
- Trial name
- NCT00382616
- Testing
- Phosphatidylserine-Omega3
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Very Low Birth Weight Infants
Efficacy of Multiple Strain Probiotics Reduces the Neurobehavioral Disorder in Premature Very Low Birth Weight Infants
The management protocols, clinical practices, equipment, infrastructure, and key personnel in NICU are unchanged during the study period.
- Trial name
- NCT03858816
- Testing
- Mixture probiotics
- Where
- Taiwan
- Sponsor
- China Medical University Hospital
PTSD
Quetiapine Treatment for Post-Traumatic Stress Disorder (PTSD)
The purpose of the study is to determine if quetiapine is effective in the treatment of PTSD.
- Trial name
- PTSD (NCT00237393)
- Testing
- Quetiapine
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Ralph H. Johnson VA Medical Center
Osteo Arthritis Knee
Multimodal Treatment of Knee Osteoarthritis: Therapeutic Exercise and Noninvasive Neuromodulation (NESA) Versus Therapeutic Exercise and Transcutaneous Electrical Nerve Stimulation (TENS) in People Over 60 Years of Age.
To analyze the effects of therapeutic exercise combined with noninvasive neuromodulation (NESA) or transcutaneous electrical nerve stimulation (TENS) on improving clinical symptoms such as joint pain and stiffness, as well as its…
- Trial name
- NCT07258693
- Testing
- Therapeutic exercise and NESA VS. Therapeutic exercise and TENS
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- University of Jaén
Substance Abuse, HIV
Electronic SBI(RT) for MSM in Argentina
The main goal of this pilot randomized controlled trial (RCT) with 200 participants is to establish the processes and procedures for a subsequent large-scale efficacy trial of an electronic-Screening, Brief Intervention, Referral…
- Trial name
- NCT05542914
- Testing
- electronic screening and brief intervention., Phase 2: Assessment Only
- Where
- Argentina
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Florida State University
Mental Health, Risk Reduction Behavior
Digital Self-help Support for Lifestyle Behavior Changes Among Primary Care Outpatients With Mental Health Problems
All patients, who have booked a first appointment with a psychologist or counselor at two primary care clinics, are asked to fill out a lifestyle screening questionnaire within the Electronic Medical Record (EMR) system.
- Conditions
- Mental Health, Risk Reduction Behavior, Primary Health Care
- Trial name
- NCT03691116
- Testing
- Digital Health Profile, Treatment as usual
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Pregnancy Related
Effects of Mind Body Exercises in Pregnant Women
his Study is a randomized controlled trial (RCT) which will be collected through non probability convenient sampling technique and will be carried out for 10 months duration with a sample size of 34 pregnant women which will be…
- Trial name
- NCT06750406
- Testing
- mind body exercises, relaxation exercises
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Acoustic Stimulation
Acoustic Stimulation, Sleep, and Cognitive-Emotional Processes in Young Adults With Anxiety and Depression Symptoms
In this study, the investigators will recruit young adults (ages 18-25 years) with elevated anxiety/depression symptoms and sleep disturbance. Participants will complete two overnights in a sleep lab.
- Trial name
- SERS (NCT05802004)
- Testing
- Acoustic Stimulation (STIM), Daily acoustic stimulation (STIM2)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Michelle Stepan
Feeding and Eating Disorders, Anorexia Nervosa
Efficacy of Juniver, a Digital Self-help Intervention, on Symptoms of Eating Disorders: A Randomised Controlled Trial
This project aims to assess the efficacy of the Juniver program on symptoms of eating disorders via a randomised controlled trial.
- Conditions
- Feeding and Eating Disorders, Anorexia Nervosa, Bulimia Nervosa, Binge-Eating Disorder
- Trial name
- NCT06226233
- Testing
- Juniver program
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- King's College London
Stress Disorders, Post-Traumatic
Train Your Brain: Neurofeedback Intervention for PTSD
The investigator's aim is to evaluate the efficacy of two types of neurofeedback treatments for PTSD symptoms reduction. Half of the participants will receive the current standard for PTSD neurofeedback care undergoing…
- Trial name
- NCT03858933
- Testing
- eBrainFit Platform
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Southern California
Inpatient Facility Diagnoses, Psychiatric Disorders
Behavioral Activation - From Inpatient to Outpatient Services
The purpose of this study is to compare the effectiveness of Behavioral Activation and Supportive Therapy added to the standard acute psychiatric inpatient care.
- Conditions
- Inpatient Facility Diagnoses, Psychiatric Disorders, Depressive Symptoms
- Trial name
- NCT01786733
- Testing
- Behavioral Activation, Supportive Therapy
- Volunteers
- 64 people
- Sponsor
- Uppsala University
Trauma Exposure, Trauma
Comparative Effectiveness of SPARCS and Unified Protocol for Youth With Chronic Medical Conditions and Trauma-Related Distress
The goal of this clinical trial is to compare the effectiveness of trauma-focused therapies for improving mental health symptoms and daily functioning in youth with chronic medical conditions who have experienced psychological…
- Conditions
- Trauma Exposure, Trauma, Trauma and Stressor Related Disorder, Mental Health Functioning
- Trial name
- NCT07483333
- Testing
- Structured Psychotherapy for Adolescents Responding to Chronic Stress - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Individual
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Anthony Vesco
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