Clinical trials: Mental Depression
Fibromyalgia, Chronic Pain
HBOT in Fibromyalgia
Fibromyalgia (FM) is a chronic pain condition affecting several millions of Canadians. Although the etiology and pathophysiology are poorly understood, there is a well-recognized association between muscular pain in fibromyalgia…
- Trial name
- NCT02467218
- Testing
- Hyperbaric Oxygen Treatment
- Where
- 2 sites in Canada
- Volunteers
- 16 people
- Sponsor
- University Health Network, Toronto
Depressive Symptoms in Patients With Epilepsy
Efficacy of taVNS Versus Sham Stimulation in Reduing Depressive Symptoms in Patients With Epilepsy: a Multi-center, Double-blinded, Randomized, 20-week, Parallel-arm, Superiority Study
The purpose of this study is to compare the efficacy of taVNS versus sham stimulation in reduing depressive symptoms in patients with epilepsy.
- Trial name
- TIDES (NCT06794034)
- Testing
- Intervention
- Where
- 5 sites in China
- Volunteers
- 158 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Depression Mild, Depression Moderate
Long-term Effects ReSet Your Mind - Mechanisms
See: ClinicalTrials.gov ID: NCT05402150 Relevant for this Paper: This investigation aims to evaluate the stability of the effectiveness of different two-week online interventions in a four months follow-up regarding reward…
- Trial name
- NCT06072209
- Testing
- Behavioral Activation, Mindfulness and Gratitude, Combination of Behavioral Activation and Mindfulness and Gratitude
- Where
- Germany
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Burnout, Professional, Stress, Psychological
Improving the Mental Health of Resident Physicians and Fellows Through Transcendental Meditation
This proposal aims to optimize resident physician and fellow wellness and performance at Banner University Medical Center through an evidence-based stress reduction program, Transcendental Meditation (TM).
- Conditions
- Burnout, Professional, Stress, Psychological, Depression, Job Stress
- Trial name
- NCT04586309
- Testing
- Transcendental meditation
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Arizona
Major Depressive Disorder
5-HTP and Creatine for Depression R33 Phase
This is a three-armed clinical trial examining the effect of 5-hydroxytryptophan and creatine monohydrate as augmenting agents for the treatment of depression.
- Trial name
- NCT05895747
- Testing
- Low Dose 5-hydroxytryptophan, High Dose 5-hydroxytryptophan, Low Dose Creatine Monohydrate
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of Utah
Dementia, Dementia, Vascular
Home-based Family Caregiver-delivered Music and Reading Interventions for People With Dementia
This international study evaluates the impact of home-based caregiver-delivered music and reading interventions for people with dementia.
- Conditions
- Dementia, Dementia, Vascular, Dementia With Lewy Bodies, Dementia, Mixed
- Trial name
- HOMESIDE (NCT03907748)
- Testing
- Music Intervention, Reading Intervention
- Where
- 5 sites in Australia, Germany and 3 more
- Volunteers
- 864 people
- Sponsor
- Anglia Ruskin University
Depressive Disorder
Study of the Telomere-telomerase System and the Expression of Candidate Genes in the Leukocytes of Patients With Depressive Disorder: Search for Peripheral Markers of Somatic Stress
The mechanisms of oxidative stress and inflammation involved in mood disorders are factors of chronicity and severity. These mechanisms induce a phenomenon of accelerated cellular senescence and are reflected by alterations in…
- Trial name
- NCT01903655
- Testing
- telomere length
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Depression, HIV Infections
Telephone Based Cognitive Behavioral Therapy for HIV Related Depression
The purpose of this study is to evaluate the effectiveness of a telephone-based, cognitive behavioral therapy intervention in the treatment of depression in adults diagnosed with HIV.
- Trial name
- NCT01055158
- Testing
- Telephone-based CBT, Enhanced Usual Care
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Maryland, Baltimore
Major Depressive Disorder
Internet-administered Interpersonal Psychotherapy for Depressive Symptoms
The aim of the study is to test the efficacy of a treatment for depression based on interpersonal psychotherapy (IPT). The treatment will be accessed via an internet platform built for this study.
- Trial name
- NCT04721678
- Testing
- Interpersonal psychotherapy
- Where
- Sweden
- Volunteers
- 113 people
- Sponsor
- Linkoeping University
Posttraumatic Stress Disorder, Depression
A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity Pilot
The goal of this pilot study is to develop and implement a larger scale, multi-site stepped collaborative care trial that targets injured patients with presentations of posttraumatic stress disorder (PTSD) and related…
- Conditions
- Posttraumatic Stress Disorder, Depression, Alcohol-Related Disorders, Suicidal Ideation
- Trial name
- TSOS6 (NCT02335125)
- Testing
- Motivational Interviewing, Cognitive Behavioral Therapy Elements, Psychotropic Drugs
- Volunteers
- 40 people
- Sponsor
- University of Washington
Multiple Sclerosis, Nurse's Role
The Effect of Nurse Practitioner (NP-led) Care Upon Mood in People With Multiple Sclerosis
MS is the leading cause of non-traumatic disability in young adults. Canada and Alberta, have the highest prevalence of people with multiple sclerosis (PwMS) in the world.
- Trial name
- NCT04388592
- Testing
- Nurse Practitioner (NP) Led Care Arm
- Where
- Canada
- Volunteers
- 248 people
- Sponsor
- University of Alberta
Neurological Development After Exposition to an Antenatal Nuchal Translucency
Follow up of Neurologic Development of Children Who Presented at the First Trimester of Pregnancy an Isolated Nuchal Anomaly With Normal Karyotype
Prospective, multicenter study following for 2 years, 250 children who presented during the first trimester of pregnancy an isolated nuchal translucency over the 95th percentile of Nicolaïdes Curves on ultrasound and comparing…
- Trial name
- EDEN (NCT02223936)
- Testing
- group exposed, Control
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Depression, Healthy
Sleep Modulation as Antidepressant Randomized Trial
The goal of this clinical trial is to learn about the effects of phase-targeted auditory stimulation in depressed patients and healthy controls.
- Trial name
- SMART (NCT05685771)
- Testing
- Phase-targeted auditory stimulation
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Giulia Da Poian
Internalizing Mental Health Symptoms, Sleep Problems
Pilot Sleep Extension and Mood
The goal of this interventional study is to learn if a digital sleep extension intervention can improve sleep and mood in young urban adults with mood symptoms.
- Trial name
- NCT06675799
- Testing
- Sleep Extension, Healthy Living Psychoeducation
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Illinois Chicago
Depression, Anxiety, Post Traumatic Stress Disorder
Effects of a Digital Diary on the Psychological Well-being of Former ICU Patients.
Previous research on the impact of a diary on mental symptoms of PICS, PICS-F, and quality of life in former ICU patients and their relatives has focused specifically on a paper diary.
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Quality of Life
- Trial name
- DIPIC (NCT06237699)
- Testing
- Digital ICU diary
- Where
- 4 sites in Netherlands
- Volunteers
- 400 people
- Sponsor
- Erasmus Medical Center
Mood Disorder, Bipolar Disorder
Examination of Brain Serotonin Receptors in Patients With Mood Disorders
The purpose of this study is to evaluate the function of certain brain chemicals and receptors in patients with mood disorders. This study will also examine how the stress hormone cortisol affects brain function.
- Conditions
- Mood Disorder, Bipolar Disorder, Depression
- Trial name
- NCT00026832
- Where
- United States
- Volunteers
- 214 people
- Sponsor
- National Institute of Mental Health (NIMH)
Quality of Life, Self Efficacy
What Concept of Manual Therapy is More Effective?
The aim of the study will be to find out which manual therapy approach is most effective for the improvement of symptoms (sensory, cognitive, emotional and social) in people with Fibromyalgia.
- Conditions
- Quality of Life, Self Efficacy, Kinesiophobia, Catastrophizing
- Trial name
- NCT05559021
- Testing
- Myofascial Therapy Treatments, Passive Mobilizations Approach
- Where
- 2 sites in Spain
- Volunteers
- 52 people
- Sponsor
- Universidad Europea de Madrid
Major Depressive Disorder
Multicenter Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder
This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, fixed-dose study in patients with a primary diagnosis of MDD according to criteria of the Diagnostic and Statistical Manual of Mental Disorders…
- Trial name
- NCT05061706
- Testing
- Lumateperone
- Where
- 50 sites in United States, Argentina and 5 more
- Volunteers
- 480 people
- Sponsor
- Intra-Cellular Therapies, Inc.
Major Depressive Disorder
Study of Mindfulness-Based Cognitive Therapy
Research aimed at assessing changes in depressogenic thinking and the ability to disengage from depressogenic thinking following Mindfulness-Based Cognitive Therapy
- Trial name
- MBCT (NCT00943033)
- Testing
- Mindfulness-Based Cognitive Therapy
- Volunteers
- 48 people
- Sponsor
- Binghamton University
Depression
Japanese Phase 1 Multiple Ascending Dose (MAD) Study
The purpose of this clinical study is to assess the safety and tolerability of multiple oral doses of BMS-820836 in healthy Japanese subjects and Japanese patients with depression.
- Trial name
- NCT01396252
- Testing
- BMS-820836
- Where
- Japan
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb