Clinical trials: Mental Exercise
Mild Cognitive Impairment
SYNchronizing Exercises, Remedies in GaIt and Cognition
The proposed SYNERGIC trial is uniquely designed to evaluate the effect of aerobic and progressive resistance training exercises, combined with cognitive training and Vitamin D3 supplementation, in cognition and mobility in older…
- Trial name
- SYNERGIC (NCT02808676)
- Testing
- Vitamin D3, Exercises (E), Cognitive Training (CT)
- Where
- 6 sites in Canada
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Sedentary Lifestyle, Dementia, Mild
Smartphone App to Improve Physical Activity in Older Adults With MCI/Mild Dementia
The purpose of this study is to develop and test a physical activity-tracking smartphone app designed to facilitate physical activity in older adults with mild cognitive impairments or mild dementia.
- Conditions
- Sedentary Lifestyle, Dementia, Mild, Mild Cognitive Impairment, Memory and Thinking Problems
- Trial name
- NCT04950998
- Testing
- Moving Up - A
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Southern California
Knee Osteoarthritis
Tai Chi and Physical Therapy for Knee Osteoarthritis
We will conduct a large randomized controlled trial comparing the effectiveness and cost-effectiveness of Tai Chi mind-body exercise and standard-of-care Physical Therapy for Knee Osteoarthritis.
- Trial name
- TCPT (NCT01258985)
- Testing
- Tai Chi, Physical Therapy
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- Tufts Medical Center
Schizophrenia, Schizoaffective Disorder
Targeting Physical Health in Schizophrenia: Physical Activity Can Enhance Life
Purpose: To develop and test the feasibility of an exercise intervention that combines group walking, activity tracking, and heart rate monitoring, and determine the effectiveness of this intervention on the physical and mental…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Brief Psychotic Disorder, Schizophreniform Disorder
- Trial name
- PACE-life (NCT03757988)
- Testing
- Exercise Intervention- PACE-Life
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- University of North Carolina, Chapel Hill
Down Syndrome, Alzheimer Disease
The Promotion of Physical Activity for the Prevention of Alzheimer's Disease in Adults With Down Syndrome
The objectives of this study are to determine the feasibility and potential efficacy of remotely delivered group exercise sessions to increase daily moderate to vigorous physical activity in adults with Down syndrome, relative to…
- Trial name
- NCT04048759
- Testing
- Remote Low, Remote High, Personal Coach
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- University of Kansas Medical Center
Obesity, Anxiety Sensitivity
Computer-Delivered Intervention for Individuals With Obesity and Elevated Anxiety Sensitivity
The proposed study will design and evaluate a computerized-delivered single-session anxiety sensitivity reduction program (i.e., Anxiety Sensitivity Training; AST).
- Conditions
- Obesity, Anxiety Sensitivity, Eating, Physical Activity
- Trial name
- NCT03917901
- Testing
- Anxiety Sensitivity Training, Health Control
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- University of Houston
Spinal Cord Injury
Study of an Implantable Functional Neuromuscular Stimulation System for Patients With Spinal Cord Injuries
OBJECTIVES: I. Establish the procedures for implementing and assessing the clinical utility of functional neuromuscular stimulation using an implanted eight-channel standing and transfer system in patients with incomplete…
- Trial name
- NCT00004445
- Testing
- Surgery, IRS-8
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Case Western Reserve University
Disability Physical, Developmental Disability
Virtual Reality Exercise in a Community Highschool for Children With Disabilities
The purpose of this study is to work with a community engagement group to develop and pilot a protocol for a virtual reality exergaming program for children with special needs at a high school.
- Conditions
- Disability Physical, Developmental Disability, Physical Inactivity
- Trial name
- NCT05935982
- Testing
- Virtual reality exercise
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Schizophrenia, Schizoaffective Disorder
Lifestyle Intervention for Young Adults With Serious Mental Illness
This is a four year project evaluating the effectiveness of a group-based lifestyle intervention (PeerFIT) supported by mobile health (mHealth) technology and social media compared to Basic Education in fitness and nutrition…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Major Depressive Disorder
- Trial name
- NCT02815813
- Testing
- PeerFIT, BEAT
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Dementia, Alzheimer's Disease
Preventing Loss of Independence Through Exercise (PLIE) in Persons With Dementia
Nearly 1 in 10 older Veterans have dementia, which is a devastating condition that leads to a progressive loss of independence and functional status. Currently available dementia medications do not alter the disease course.
- Trial name
- PLIE-VA (NCT02350127)
- Testing
- Preventing Loss of Independence through Exercise (PLIE), Usual Care
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- VA Office of Research and Development
Schizophrenia
Aerobic Exercise for Cognition in Schizophrenia
This study will evaluate the ability of aerobic exercise (AE) to improve cognition in people with schizophrenia. Participants will be randomly assigned to one of two interventions: (1) aerobic exercise class (stationary bicycle…
- Trial name
- NCT02621983
- Testing
- Aerobic Exercise, Balance and Stretching
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Office of Research and Development
Chronic Low Back Pain, Posttraumatic Stress Disorder
Exercise Maintenance in Chronic Pain and PTSD
The primary purpose of the R21 is using an experimental medicine research approach to study whether a chronic, progressive-based exercise program will help Veterans suffering from chronic low back pain (cLBP) and PTSD achieve…
- Trial name
- NCT03644927
- Testing
- Progressive exercise training, Waitlist Control
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Boston University
Psychiatric Diagnosis
A Digital Intervention to Improve Physical Activity and Sleep Behaviors in Youth With Psychiatric Diagnoses
The goal of "GamerFit" is to test the delivery of a theory-based mHealth app that utilizes social support, exergaming, and telehealth coaching to improve PA levels, sleep, and psychiatric symptoms among youth participants (ages…
- Trial name
- GamerFit (NCT05505578)
- Testing
- GamerFit Condition, Comparator Condition
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- Pennington Biomedical Research Center
Sleep Initiation and Maintenance Disorders, Sleep Disorders, Intrinsic
The Effectiveness of Regular Exercise on Improving Sleep in Older Adults
This study will evaluate the effect of regular aerobic exercise on improving sleep in older adults with moderate difficulty sleeping.
- Trial name
- RTC (NCT00149747)
- Testing
- Moderate-Intensity Aerobic Physical Activity, Health Education Class
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Stanford University
Depressive Disorder
Levodopa and Exercise for Older Adults With Depression and Psychomotor Slowing
In this new research study, 80 adults aged > 60 years with a significant depressive disorder and slowed processing and/or gait speed will be randomized to receive levodopa (L-DOPA; which the Candidate has previously shown to…
- Trial name
- NCT04650217
- Testing
- Carbidopa/levodopa, Exercise training, Control
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- New York State Psychiatric Institute
Cognitive Dysfunction, Dementia, Mild
FitMi AD Home Therapy for Individuals With MCI or Mild Dementia Due to Alzheimer's Disease
This study will investigate the efficacy of a newly developed exercise device (FitMi AD) for individuals with mild cognitive impairment (MCI) or mild dementia due to Alzheimer's disease.
- Trial name
- NCT05504811
- Testing
- FitMi AD, Conventional exercise program
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Flint Rehabilitation Devices, LLC
Cognitive Impairment, Mild, Cognitive Decline
Efficacy of a Multimodal Brain Health Intervention for Older African Americans
This study tests the feasibility, acceptability, and efficacy of a multimodal intervention (walking, social engagement, and reminiscence), including the use of wearable digital biomarkers, for cognitively healthy and mildly…
- Trial name
- SHARP (NCT04863378)
- Testing
- Walking conversational reminiscence
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Cardiac Arrest, Post Traumatic Stress Syndrome
Family-Authored ICU Diaries to Reduce Fear in Patients Experiencing a Cardiac Arrest (FAID Fear)
The present study will: Aim 1: Enroll 15 family members of CA patients to (a) pilot recruitment procedures, (b) estimate retention, and (c) assess acceptability of study procedures.
- Trial name
- FAID Fear (NCT05144477)
- Testing
- FAID Fear Intervention
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Columbia University
Overweight and Obesity, Physical Inactivity
A 12-week Field Trial of the Move Physical Activity Support Program
The objective of this study is to design and refine an activity support program for overweight or obese adults called Move. The primary outcomes are feasibility and acceptability of the Move physical activity support program.
- Trial name
- NCT05865392
- Testing
- Move physical activity support program
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Osteoporosis
Green Tea and Tai Chi for Bone Health
Osteoporosis is a major health problem in postmenopausal women. Our long-term goal is to develop a new alternative treatment that include a dietary supplement (green tea extract) and a mind-body exercise (Tai Chi) for lessening…
- Trial name
- GTP-TC-Bone (NCT00625391)
- Testing
- Green Tea Polyphenols (GTP), GTP+TC
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center