Clinical trials: Mental Health (Depression)
Severe Mental Disorder, Schizophrenia
Community-based Mental Health Care for People With Severe and Enduring Mental III Health ( RECOVER-E )
A single-blinded hybrid effectiveness-implementation trial (Type II), that both evaluates the intervention outcomes (clinical and service use outcomes) through patient-randomization in the implementation sites, as well as…
- Conditions
- Severe Mental Disorder, Schizophrenia, Bipolar Disorder, Severe Depression
- Trial name
- NCT03892473
- Testing
- Community mental health teams (CMHT), Care as usual (CAU)
- Where
- North Macedonia
- Volunteers
- 160 people
- Sponsor
- University of Skopje
Psychological Stress, Psychosocial Impairment
Evaluation of the Psychosocial Impact on Health Professionals Exposed During COVID 19 Coronavirus Pandemic
Application of a survey in electronic support to hospital professionals. This survey will include different demographics as well as questions from own elaboration about the different aspects related to the development of work…
- Conditions
- Psychological Stress, Psychosocial Impairment, Anxiety, Depression
- Trial name
- NCT04752839
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Low Back Pain, Depression
Subgroups of Older Adults With Back Pain and Multiple Chronic Conditions
The overall goal of this study is to use the National Health and Aging Trends Study (NHATS) data to gain an understanding of how multiple chronic conditions impact the health outcomes of older adults with back pain.
- Conditions
- Low Back Pain, Depression, Anxiety, Osteoarthritis
- Trial name
- NCT03632122
- Where
- United States
- Volunteers
- 8,344 people, healthy volunteers welcome
- Sponsor
- University of Washington
Surgery
INCLUDE Program: A Perioperative Wellness Program Tailored for Black Surgical Patients
In this study, the investigators will evaluate the feasibility of the Wellness Program, including patient recruitment, screening and outcome measures, and feasibility of adapting the intervention with older Black surgical…
- Trial name
- NCT07283783
- Testing
- Wellness Program
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Washington University School of Medicine
Stroke, Multiple Sclerosis
Quality of Life Assessment Between Stroke and Multiple Sclerosis Patients of the Same Age Range
The purpose of this study is to investigate the physical, psychological, social and functional aspects of life in relatively young people suffering from vascular stroke and in people diagnosed with multiple sclerosis of the same…
- Conditions
- Stroke, Multiple Sclerosis, Quality of Life, Depression
- Trial name
- QoLSMS (NCT04758494)
- Testing
- Questionnaire
- Where
- Greece
- Volunteers
- 172 people
- Sponsor
- Hellenic Red Cross Hospital
Human Immunodeficiency Virus, Smoking Cessation
Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV
Smokers living with HIV represent a major health disparity population in the United States and the world more generally. Major contributing factors to the maintenance and relapse of smoking among smokers living with HIV include…
- Conditions
- Human Immunodeficiency Virus, Smoking Cessation, Smoking, Cigarette, Smoking
- Trial name
- NCT03904186
- Testing
- QUIT, Time-Matched Control (TM)
- Where
- 3 sites in United States
- Volunteers
- 131 people
- Sponsor
- Massachusetts General Hospital
Maternal Health Services, Infant, Newborn
Comparing Integrative Midwife-led vs. Fragmented Inpatient Postpartum Care: Impact on Satisfaction and Transition to Motherhood
The goal of this clinical trial is to compare two different forms of postnatal care to find out which is most beneficial for mothers and their children after birth and with which they are most satisfied.
- Conditions
- Maternal Health Services, Infant, Newborn, Postnatal Care, Breast Feeding
- Trial name
- SMILE (NCT07077941)
- Testing
- Integrative care
- Where
- Austria
- Volunteers
- 784 people
- Sponsor
- Medical University of Vienna
Major Depressive Disorder
VA Augmentation and Switching Treatments for Improving Depression Outcomes
The overall purpose is to determine research based 'next-steps' for outpatients with major depressive disorder who have not had satisfactory outcomes to standard 'first-step' treatments.
- Trial name
- VAST-D (NCT01421342)
- Testing
- Switching: Bupropion-SR, Augmenting: Antidepressant + Bupropion-SR, Augmenting: Antidepressant + Aripiprazole
- Where
- 35 sites in United States
- Volunteers
- 1,522 people
- Sponsor
- VA Office of Research and Development
Anxiety Disorders, Depression
Hot Water Immersion Therapy for Mental Health
In 2016, it was estimated that nearly 1 billion people worldwide were affected by a mental or addictive disorder, and were associated with considerable excess mortality. Acute heat therapy sessions (e.g.
- Conditions
- Anxiety Disorders, Depression, Post-traumatic Stress Disorder, Heat
- Trial name
- WITHME (NCT04793542)
- Testing
- lower-limb hot water immersion
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Lakehead University
Gender-based Violence, Adherence
Impacts of Clean Cookstoves and Empowerment Training on Women's Health in Refugee Settings
The main objective of this study is to understand the links and outcomes of adoption of a cleaner cookstove/fuel and exposure to a personal empowerment training on women's health outcomes in a Congolese refugee camp in Rwanda…
- Conditions
- Gender-based Violence, Adherence, Mental Health Wellness 1, Empowerment
- Trial name
- NCT04081441
- Testing
- Inyenyeri clean cookstove and fuel system, I-ACT (Individual, Agency-Centered Training) workshop
- Where
- Rwanda
- Volunteers
- 1,555 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Depressive Disorder, Major
Combining Data Sources to Identify Effect Moderation for Personalized Mental Health
This work will extend and apply methods for modeling heterogeneous treatment effects when multiple studies are available, with a particular focus on the complexities in mental health research.
- Trial name
- NCT05267873
- Testing
- Duloxetine, Vortioxetine
- Where
- United States
- Volunteers
- 9,586 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Depression - Major Depressive Disorder, Anxiety Disorders
AI-Guided CBT for Depression and Anxiety
This study aims to evaluate the effectiveness of an artificial intelligence (AI)-guided cognitive behavioral therapy (CBT) program for the treatment of mild depression and anxiety disorders in adults.
- Trial name
- AI-CBT-DA (NCT07576686)
- Testing
- AI-Guided Cognitive Behavioral Therapy, Cognitive Behavioral Therapy (CBT)
- Where
- Serbia
- Volunteers
- 120 people
- Sponsor
- Aleksandra Stojanovic
Stroke, Intracerebral Hemorrhage
ACT-group for Stroke Survivors (Pilot Study)
The goal of this clinical pilot trial is to test the feasibility, acceptance and preliminary efficacy of an adapted group psychotherapy manual in stroke survivors with psychological stress.
- Conditions
- Stroke, Intracerebral Hemorrhage, Depressive Symptoms, Anxiety
- Trial name
- NCT06282029
- Testing
- Group Therapy
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- Bielefeld University
Major Depression, Mental Health
Provigil in Conjunction With SSRIs for the Treatment of Mild or Moderate Depression With Attendant Symptoms of Sleepiness and Fatigue.
The main purpose of this study is to determine if Provigil® (modafinil) at a dose of 200 mg once daily is safe and effective for treating symptoms of sleepiness and fatigue associated with Major Depressive Disorder when added to…
- Trial name
- NCT00208715
- Testing
- Provigil
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Mental Health Wellness 1, Depression
Randomised Controlled Trial of Method of Levels Cognitive Therapy
The purpose of this study is to determine whether Method of Levels Cognitive Therapy is an effective intervention for treating clients with a range of presenting problems in primary care by comparing it with a waiting list…
- Conditions
- Mental Health Wellness 1, Depression, Anxiety
- Trial name
- NCT01554150
- Testing
- Method of Levels Cognitive Therapy
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- University of Manchester
Diabetes Mellitus, Type 2, Depression, Anxiety
Interactive Virtual Assistance for Self-Care Management and Mental Health Promotion in Type 2 Diabetes
BACKGROUD: Health technology is an important tool in the aging process, which may improve the health condition and self-esteem of the elderly, in addition to offering new opportunities and challenges.
- Conditions
- Diabetes Mellitus, Type 2, Depression, Anxiety, Mental Health Disorder, Old Age; Debility
- Trial name
- NCT05329376
- Testing
- Smart Speaker Echo Dot, Usual Care
- Where
- Brazil
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Psychosis, Anxiety
Acute Psychiatric Care at Home for Lower-risk Patients With Acute Psychiatric Illness Who Require Inpatient Care
The goal of this pilot randomized controlled trial is to learn if adult patients with acute psychiatric conditions can receive hospital-level care at home. The main question it aims to answer is: 1.
- Conditions
- Psychosis, Anxiety, Depression, Behavioral and Psychiatric Symptoms of Dementia
- Trial name
- BHH (NCT07364825)
- Testing
- Behavioral Health Home Hospital
- Where
- 4 sites in United States
- Volunteers
- 41 people
- Sponsor
- Brigham and Women's Hospital
Mental Health Issue, Musculoskeletal Pain
Sustainable UNiversity Life (SUN) Study
In 2017, Socialstyrelsen reported that mental ill-health in young adults had increased by almost 70% in the previous10 years. A 2014 report showed that 5% of men and 11% of women 18-24 years were diagnosed with depression or…
- Trial name
- SUN (NCT04465435)
- Testing
- Web-based self-report questionnaires, Focus Group Interviews
- Where
- Sweden
- Volunteers
- 4,262 people
- Sponsor
- Sophiahemmet University
Depression
Evaluating the Impact AI Avatar-led Mental Health Interventions for Keeping Employees in Work
This study will examine whether an artificial intelligence (AI) avatar-led mental health programme can help employees experiencing symptoms of depression.
- Trial name
- NCT07436117
- Testing
- Remi, AI avatar-led cognitive behavioural therapy intervention
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Roehampton
Adjustment Disorder, Anxiety
Online MBCT for Adjustment Disorder During COVID-19: Efficacy, Mechanisms, and RCT
This study tested a 4-week, internet-based Mindfulness-Based Cognitive Therapy (MBCT) program designed to help people experiencing adjustment disorder during the COVID-19 pandemic.
- Conditions
- Adjustment Disorder, Anxiety, Depressive
- Trial name
- NCT07128017
- Testing
- Mindfulness-Based Cognitive Therapy (Internet-delivered), Progressive Muscle Relaxation (Internet-delivered), No Intervention - Waitlist Control
- Where
- Poland
- Volunteers
- 301 people
- Sponsor
- University of Warsaw