Clinical trials: Mental Health (Depression)
Depression, Anxiety
Mental Health E-screening in Pregnant and Postpartum Women
To compare e-screening versus usual screening on: 1) women's and healthcare providers' views on feasibility and acceptability; 2) rates of detection of prenatal and postpartum depression and anxiety; 3) perceived risk and benefit…
- Trial name
- NCT01899534
- Testing
- E-screening
- Where
- 3 sites in Canada
- Volunteers
- 566 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Group Meetings
Feasibility of Therapy Integrating Peer-sharing, Technology, Aerobic and Resistance Training (TIPSTART)
The purpose of this randomized controlled clinical trial with first-generation college students with symptoms of mental illness is to test the preliminary feasibility and efficacy of TIPSTART, a multi-faceted, mental health and…
- Trial name
- TIPSTART (NCT04813198)
- Testing
- TIPSTART
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Alcohol Dependence
Lifestyle Physical Activity Intervention for Depressed Alcohol Dependent Women
Building on the large body of evidence for the effect of exercise in decreasing depressive symptoms and the few preliminary findings of its effect on craving and drinking outcomes, the purpose of this study is to develop a…
- Trial name
- NCT02705898
- Testing
- LPA+Fitbit, HEC
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Butler Hospital
Burnout, Stress
Effectiveness of Interventions to Improve Resiliency & Burnout in Behavioral Health Residential Staff
The goal of this clinical trial is to compare Integrated Resiliency Training and Task Sharing (IRTTS) to Workplace Improvement Learning Collaborative (WILC) in group homes for adults with serious mental illness and/or…
- Conditions
- Burnout, Stress, Coping Skills, Depression
- Trial name
- NCT05806112
- Testing
- Resiliency Training, Task Sharing, Workplace Improvement Learning Collaborative
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Massachusetts General Hospital
Depression - Major Depressive Disorder, ANXIETY DISORDERS (or Anxiety and Phobic Neuroses)
Is Betwixt App Effective and Acceptable?
Title Is the Betwixt application effective and acceptable in improving emotion regulation for an adult clinical population? Short title Betwixt: Effective/acceptable clinical population emotion regulation? Chief Investigator…
- Trial name
- NCT06958887
- Testing
- Betwixt app intervention
- Where
- United Kingdom
- Volunteers
- 7 people
- Sponsor
- University of Nottingham
University Students, Psychological Well Being
Development of the Online Mindfulness-based Intervention (Mind Space Application) for Thai-university Students: Phase II
Development of the online mindfulness-based intervention (MFU-mindful Application for Thai university students: Phase II Objectives: Phase I: (October 2025 to September 2026) 1.
- Conditions
- University Students, Psychological Well Being, Mindfulness
- Trial name
- NCT07346612
- Testing
- mind space intervention
- Where
- Thailand
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Mae Fah Luang University
Bipolar Disorder, Non-Adherence, Medication
Using mHealth to Improve Adherence and Reduce Blood Pressure in Individuals With Hypertension and Mood Disorders
This proposed 2-stage randomized controlled trial (RCT) will evaluate a personalized patient-centered adherence intervention iTAB-CV + Self-Monitoring (iTAB-CV + SM) vs.
- Conditions
- Bipolar Disorder, Non-Adherence, Medication, Hypertension, Major Depressive Disorder
- Trial name
- iTAB-CV RCT (NCT04675593)
- Testing
- iTAB-CV, Self-Monitoring
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Case Western Reserve University
Depression, Postpartum, Anxiety State
From Prevention to Treatment: How Biological Rhythms Can Maintain Perinatal Mental Health
Depression and anxiety are significant public health issues during pregnancy and the postnatal period, particularly affecting those in developing countries.
- Trial name
- NCT06246214
- Testing
- Blue Light Therapy, ControlLT
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Mild Cognitive Impairment
WAVE: AudioVisual Stimulation Enhances Cognitive, Mental and Physical Health in Elderly
The goal of this randomized controlled trial is to 1) carry out a screening of cognitive function, depressive symptoms, agility and functional balance and chronic inflammatory conditions in older adults; 2) analyze the influence…
- Trial name
- NCT06686563
- Testing
- Intervention Group: Gamma stimulation, Control Group: Theta stimulation
- Where
- Portugal
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Maria Paço
Mental Health, Neurological Health
Brain Cooling Biomarkers
This research is being done to examine the effects of brain cooling on cognition, electrophysiological brain activity via EEG scans, inflammation of the brain, and mood in healthy subjects.
- Trial name
- NCT06542419
- Testing
- Brain Cooling
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Penn State University
Maternal Distress, Perinatal Depression
A Common Elements-based Intervention to Improve Maternal Psychological Well-being and Mother-infant Interaction
Background: Millions of children in low resource settings are at high risk of poor development due to factors such as undernutrition, inadequate stimulation and maternal depression.
- Conditions
- Maternal Distress, Perinatal Depression, Development Delay, Language Delay
- Trial name
- NCT04252807
- Testing
- Intervention arm, Treatment as Usual
- Where
- Pakistan
- Volunteers
- 250 people
- Sponsor
- Human Development Research Foundation, Pakistan
Anxiety Depression
Mindfulness-Based Art Therapy and Generation Z
A randomized controlled trial will be conducted to determine the unique role of the arts as a proactive mental health strategy for college students in Generation Z.
- Trial name
- NCT04834765
- Testing
- Mindfulness-based art therapy, Art-only, Mindfulness-only
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Florida State University
Cardiac Arrest, Cognitive Function
Brain Function After Cardiac Arrest (Measured With FMRI and Cognitive Tests)
The aim of this longitudinal study is to determine whether brain function is affected after a cardiac arrest. The primary question is whether cognitive function is affected after cardiac arrest and whether it changes over time…
- Trial name
- BRAINnHEART (NCT03579498)
- Where
- 2 sites in Norway, Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Postnatal Depression
Digital Assessment of Well-being in New Parents
The mental health of new parents around the time of the birth of their baby has been identified as a key priority in the NHS (National Health Service) Long Term plan.
- Trial name
- DAWN-P (NCT04279093)
- Testing
- No intervention, but participants will use a smartphone app daily to complete the EPDS
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Emily Eisner
Depression, Anxiety
Development and Evaluation of a CBT-based Transdiagnostic Transcultural Web App for Mental Health Problems
This study aims to (1) develop a CBT-based transcultural, transdiagnostic interactive web app and (2) assess the feasibility, acceptability, and preliminary efficacy of this intervention.
- Trial name
- WCBT (NCT06158763)
- Testing
- Web-based CBT guided self-help Interventions
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Pakistan Association of Cognitive Therapists
Depressive Disorders
Evaluation of a Psychoeducation Group Program for Mild/Moderate Depression
The purpose of this study is to compare the effectiveness and efficiency of doing a psychoeducational group program and the conventional treatment versus individual conventional care in patients with a mild/moderate depression…
- Trial name
- NCT00841737
- Testing
- Psychoeducational group, Control Group
- Where
- 2 sites in Spain
- Volunteers
- 192 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Depression, Anxiety
Development, Feasibility and Effectiveness of a Digital Support Platform for Mental Health in Primary Care (PRESTO).
The prevalence of mental health disorders in Primary Care (PC) largely exceeds the limited resources available. The main aim of this project is to develop a comprehensive machine learning (ML) digital support platform (PRESTO) to…
- Trial name
- PRESTO (NCT04559360)
- Testing
- PRESTOapp
- Volunteers
- 152 people
- Sponsor
- Hospital Clinic of Barcelona
Psychological Well-being, Gratitude
Effects of School-Based Ignatian Examen Meditation on Well-Being, Gratitude, Hope, and Spirituality in Hong Kong Catholic Primary School Students
This study aims to investigate the effects of Ignatian Examen Meditation on students' psychological well-being, gratitude, hope, and spirituality.
- Conditions
- Psychological Well-being, Gratitude, Hope, Spirituality
- Trial name
- NCT07857980
- Testing
- Examen Meditation
- Where
- Hong Kong
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Depressive Disorder, Mood Disorder
Family Based Treatment of Depressed Adolescents (AHUS)
Major depressive disorder (MDD) affects about 5% of adolescents and is on the rise both internationally and in Norway. Further, it is also associated with increased risk for suicide.
- Conditions
- Depressive Disorder, Mood Disorder, Major Depression
- Trial name
- BudFam2 (NCT01830088)
- Testing
- Attachment Based Family Therapy, Enhanced Usual Care
- Where
- Norway
- Volunteers
- 62 people
- Sponsor
- University Hospital, Akershus
Mental Health Issue, Breast Cancer
A Pre-post Pilot of a Smartphone Intervention
Digital mental and behavioral health interventions have potential to significantly improve accessibility for the large number of breast cancer survivors who need treatments.
- Trial name
- NCT07665346
- Testing
- Digital Micro-Interventions
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Virginia
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