Clinical trials: Mental Health (Depression)
Health Behavior, Work Related Stress
HRV and Coaching Preparation Phase Study
This pilot study will evaluate possible intervention components to be included in a future stress management and health behaviour change trial and to pilot test their feasibility and acceptability in a small sample.
- Conditions
- Health Behavior, Work Related Stress, Job Stress, Anxiety Depression
- Trial name
- NCT05150574
- Testing
- Core Health Program, Daily resting HRV, Momentary HRV feedback
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Brock University
Psychosocial Problem, Psychological Distress
Evaluating Impacts of CSS for Veterans and Their Families in Ukraine
This cluster-randomized controlled trial (c-RCT) evaluates the effectiveness of a brief, single-session psychosocial workshop, "CETA Short Session" (CSS), for reducing symptoms of distress and functional impairment and increasing…
- Conditions
- Psychosocial Problem, Psychological Distress, Engagement, Patient
- Trial name
- NCT04234815
- Testing
- CETA Short Session (CSS), Psychoeducation and Safety
- Where
- Ukraine
- Volunteers
- 1,193 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Mental Health Issue, Depression/Anxiety
Psychiatric Consultation-Liaison Intervention in Primary Care: A Pilot Study
The pilot study on the impact of a Psychiatric Consultation-Liaison Intervention in Primary Care Medical Consultations in French-speaking Switzerland (PLIMeC-P), is a mixed method randomized controlled trial.
- Conditions
- Mental Health Issue, Depression/Anxiety, Quality of Life, Psychosomatic Disorders
- Trial name
- PLIMeC-P (NCT06377189)
- Testing
- Intervention arm - Consultation-Liaison (CL) brief psychiatric intervention in primary care settings, Control Arm - Treatment As Usual (TAU)
- Where
- 3 sites in Switzerland
- Volunteers
- 30 people
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
Partner Abuse, Depression
Addressing Intimate Partner Violence, Mental Health, and HIV in Antenatal Care
This quasi-experimental feasibility study recruit n=40 participants from each of two public antenatal clinics in Johannesburg, South Africa. Using the Bowen et al.
- Conditions
- Partner Abuse, Depression, Adherence, Medication
- Trial name
- NCT05389358
- Testing
- Asiphephe health worker training, Asiphephe therapeutic sessions, IPV assessment
- Where
- 2 sites in South Africa
- Volunteers
- 80 people
- Sponsor
- University of Witwatersrand, South Africa
Cognitive Function, Well-Being
Singing Groups for Seniors: Well-Being, Cognitive Function and Health
The researchers' implement and measure the effects of a singing group intervention program for older adults, with an RCT design, in a natural context, on the health, well-being and cognitive function of older adults.
- Conditions
- Cognitive Function, Well-Being, Physical Function, Respiratory Function
- Trial name
- Sing4Health (NCT03985917)
- Testing
- Singing Group Intervention Program, Alternative Social and Leisure Activities
- Where
- Portugal
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Iolanda Costa Galinha
Depression, Pre-Exposure Prophylaxis
Friendship Bench Mental Health Intervention for Adolescent Girls and Young Women in South African PrEP Delivery Settings
Adolescent girls and young women (AGYW) at risk of HIV in sub-Saharan Africa, frequently (20-50%) have symptoms of common mental disorders, including depression, anxiety, and stress.
- Trial name
- NCT05664490
- Testing
- Youth Friendship Bench SA
- Where
- South Africa
- Volunteers
- 116 people
- Sponsor
- University of California, San Francisco
Musculoskeletal Diseases, Chronic Pain
Wellness Through Mobile Health
This pilot project will evaluate the potential of an affordable smartphone app to improve users' mental well-being.
- Conditions
- Musculoskeletal Diseases, Chronic Pain, Anxiety Disorders, Depression
- Trial name
- NCT04640090
- Testing
- Smartphone app (Wysa)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Washington University School of Medicine
Premature Infant, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Preventing Vulnerable Child Syndrome in the NICU With Cognitive Behavioral Therapy (PreVNT Trial)
This study is being done to see if outcomes for both a premature infant's parents and the infant born prematurely who have spent time in the neonatal intensive care unit (NICU) can be improved through parent cognitive behavioral…
- Conditions
- Premature Infant, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Development, Child, Parent-Child Relations
- Trial name
- PreVNT (NCT03906435)
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Resilience, Connectedness
This Study Explores the Mental Health Impact of Two Akashic Records Sessions.
The goal of this clinical study is to learn the impact of two Akashic Records sessions on mental health symptoms in adults. We want to see how sessions are linked to stress, anxiety, and depression, and to resilience (ability to…
- Conditions
- Resilience, Connectedness, Depression, Anxiety
- Trial name
- Akashic Record (NCT07219914)
- Testing
- Akashic Records Session
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- Rasa Healing Inc
Pregnancy, Postpartum
HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children
Regular exercise during pregnancy and postpartum leads to health benefits for mother and child. Inactivity during pregnancy and after delivery is now treated as risky behavior.
- Conditions
- Pregnancy, Postpartum, Childbirth, Health Status
- Trial name
- HIIT MAMA (NCT05009433)
- Testing
- High intensity interval training program for pregnant women, Moderate intensity continuous training program for pregnant women, Standard obstetric care with extended education on healthy lifestyle
- Where
- Poland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Perceived Stress, Depression
Online Yoga for Improving the Well-being of Desk-based Workers
The goal of this clinical trial is to evaluate the effectiveness of an 8-week online yoga intervention in improving the well-being and productivity of desk-based workers.
- Conditions
- Perceived Stress, Depression, Anxiety, Mindfulness
- Trial name
- NCT06289426
- Testing
- Yoga
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kingston University
Mental Health Disorder, Post-Traumatic Stress Disorder in Adolescence
Promoting Asylum-seeking and Refugee Children's Coping With Trauma
A short term trauma-focused cognitive- behavioral program to reduce trauma-related mental health problems among asylum-seeking and refugee children.
- Conditions
- Mental Health Disorder, Post-Traumatic Stress Disorder in Adolescence, Depression, Social Anxiety
- Trial name
- NCT03822598
- Testing
- Teaching Recovery Techniques, TRT
- Where
- 16 sites in Norway
- Volunteers
- 170 people
- Sponsor
- Norwegian Institute of Public Health
Post-Partum Depression
Managing PPD at Gouverneur
A Stepped Care pathway for managing postpartum depression (PPD) in pediatric primary care settings will be used to (1) understand context for implementation feasibility (2) evaluate benefits for mother and child.
- Trial name
- NCT02738021
- Testing
- STRONG
- Sponsor
- NYU Langone Health
Periodontitis, Depression
Impact of Periodontal Therapy on Mental Health Parameters
Objectives: Primary: To determine the efficacy of periodontal treatment on mental health outcomes in patients with major depression and periodontitis.
- Trial name
- LeakBrainRCT (NCT06036472)
- Testing
- Standard periodontal therapy (steps 1 & 2), supragingival debridement with anesthesia (step 1)
- Where
- 2 sites in Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Complutense de Madrid
Psychological Stress, Depressive Symptoms
Effectiveness of Medicorp HO Preparatory Course
After completion of 5 years of medical school training, the next step of becoming a House Officer is said to be associated with high levels of stress.
- Conditions
- Psychological Stress, Depressive Symptoms, Anxiety State, Motivation
- Trial name
- NCT03510195
- Testing
- MEDICORP HO PREPARATORY MODULE
- Where
- Malaysia
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Postpartum Depression (PPD), Postpartum Anxiety
mHealth Intervention to Prevent Postpartum Depression and Anxiety in Chilean Women (WWWT)
The goal of this clinical trial is to evaluate the effectiveness of a digital psychoeducational intervention, "What Were We Thinking" (WWWT), to prevent the development of postpartum depression and anxiety symptoms in first-time…
- Trial name
- NCT07587177
- Testing
- What Were We Thinking (WWWT) mHealth Intervention
- Volunteers
- 220 people
- Sponsor
- Universidad del Desarrollo
Perinatal Depression, Social Support
Midwife-led Cognitive Behavioral Intervention for Perinatal Depression. Multisite RCT
Perinatal depression(PND), or depression during pregnancy and within one year following childbirth, is the most burdensome maternal mental illness. Women in low-income countries like Ethiopia have suffered from the disease.
- Conditions
- Perinatal Depression, Social Support, Perceived Stress
- Trial name
- NCT07800299
- Testing
- Midwife-led Cognitive Behaviroal Intervention
- Where
- 3 sites in Ethiopia
- Volunteers
- 192 people
- Sponsor
- The Hong Kong Polytechnic University
Depression, Suicidality
Development and Preliminary Trial of a Brief, Portable Health Intervention for Rural Sexual Minority Emerging Adults
The purpose of this study is to test the feasibility of writing interventions specifically designed for lesbian, gay, and bisexual (LGB) emerging adults (ages 18-29) that are aimed at improving the outcomes: depression…
- Conditions
- Depression, Suicidality, Substance Abuse, HIV
- Trial name
- Project LEAP (NCT03751020)
- Testing
- Expressive Writing (EW) Intervention, Self-Affirmation (SA) Intervention, Control
- Where
- 3 sites in United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yale University
Sleep Deprivation, Depression
Work Hour Reductions, Medical Errors, and Intern Well-Being at Providence St. Vincent Medical Center Intensive Care Unit
The purpose of this study is to determine whether reducing intern work hours and eliminating extended shifts in the intensive care unit will reduce prescribing errors and improve intern well-being.
- Trial name
- NCT00996320
- Testing
- Reduced work hour schedule
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Providence Health & Services
Cystic Fibrosis (CF)
TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age
This is a longitudinal, observational epidemiological study designed to estimate the prevalence of depression, anxiety, and behavior problems in children ages 18 months through 11 years with cystic fibrosis (CF).
- Trial name
- TIDES 2 (NCT07048574)
- Where
- 13 sites in United States
- Volunteers
- 600 people
- Sponsor
- State University of New York at Buffalo
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