Clinical trials: Mental Health (Depression)
Depressive Disorder, Major
Combining Data Sources to Identify Effect Moderation for Personalized Mental Health
This work will extend and apply methods for modeling heterogeneous treatment effects when multiple studies are available, with a particular focus on the complexities in mental health research.
- Trial name
- NCT05267873
- Testing
- Duloxetine, Vortioxetine
- Where
- United States
- Volunteers
- 9,586 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Mental Health Wellness 1
#Stayhealthy - Monitoring and Maintenance of Mental Health Under Conditions of Social Isolation During the Corona Crisis
The COVID-19 pandemic has led to a global health crisis with, so far, over 21 million registered cases and more than 700.000 deaths worldwide.
- Trial name
- stayhealthy (NCT04871386)
- Testing
- Acceptance and commitment therapy (ACT) exercises, Positive psychology (PP) exercises
- Where
- Germany
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Depression, Depression/Anxiety
START NOW Adapted: Culturally Adapted Version of START NOW
The goal of this clinical trial is to test the effectiveness of the culturally adapted skills-training START NOW in youth migrant populations.
- Conditions
- Depression, Depression/Anxiety, Anxiety, Adolescent
- Trial name
- NCT06324864
- Testing
- START NOW Adapted
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- Prof. Christina Stadler
Psychosis, Substance Abuse
Effect Evaluation of Individual Placement and Support (IPS)
Roughly one third of disability pensions issued in Norway are classified as mental and behavioral disorders. The proposed study aims to evaluate the effect of an innovative intervention for returning people with moderate to…
- Conditions
- Psychosis, Substance Abuse, Depression, Anxiety
- Trial name
- NCT01964092
- Testing
- Individual Placement and Support, Ordinary employment schemes
- Where
- Norway
- Volunteers
- 410 people
- Sponsor
- NORCE Norwegian Research Centre AS
Depression and Quality of Life
ICBT for Mental Health Problems Related to the Climate Crisis
The study seeks to investigate the effects of a guided internet-based cognitive behavioral therapy (ICBT) programme on adult mental health problems related to the climate crisis.
- Trial name
- NCT05169736
- Testing
- Cognitive Behavioural Therapy
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Linkoeping University
Depression
Using a Mentoring Afterschool Program to Improve Adolescent Mental Health and Physical Activity: A Pilot Study
Coming out of the COVID-19 pandemic many youth are experiencing declines in physical activity and worsening mental health (e.g., depression symptoms).
- Trial name
- NCT06686784
- Testing
- After School Plus
- Where
- United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Depression
Mobile Mental Health in Community-Based Organizations
Untreated depression is a significant cause of morbidity and mortality among women in low and middle- income countries (LMIC). The investigators propose to develop and test the feasibility an interactive voice-response, mobile…
- Trial name
- MITHRA (NCT04480021)
- Testing
- MITHRA, EUC
- Where
- India
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Washington
Perceived Stress, Depression
Online Yoga for Improving the Well-being of Desk-based Workers
The goal of this clinical trial is to evaluate the effectiveness of an 8-week online yoga intervention in improving the well-being and productivity of desk-based workers.
- Conditions
- Perceived Stress, Depression, Anxiety, Mindfulness
- Trial name
- NCT06289426
- Testing
- Yoga
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kingston University
Health Services for the Aged, Frailty
e-GAB: Electronic Geriatric Assessment Bundle: Development of an Arabic Self-administered Android CGA Application
The aim of this study is to design and assess the accuracy of administering the electronic Geriatric Assessment Bundle (e-GAB) compared to geriatrician performed comprehensive geriatric assessment (CGA) in a group of Egyptian…
- Conditions
- Health Services for the Aged, Frailty, Cognitive Impairment, Depression
- Trial name
- NCT04211285
- Testing
- e-GAB, standard physician performed CGA
- Where
- Egypt
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Major Depressive Disorder
Appalachian Mind Health Initiative
We propose to carry out a treatment experiment in which we evaluate the extent to which randomizing primary care clinicians have access to remote internet-based Cognitive Behavior Therapy (eCBT) in rural West Virginia (WV) and…
- Trial name
- AMHI (NCT04120285)
- Testing
- remote internet-based cognitive behavior therapy (eCBT)
- Where
- 7 sites in United States
- Volunteers
- 1,280 people
- Sponsor
- University of South Florida
Pregnancy Related, Mental Health Issue
MamaConecta: Digital Tool for Maternal Mental Health
The goal of this randomized controlled trial is to validate a digital health tool, Dana app, that enhances well-being and supports mental health monitoring for women during the perinatal period.
- Conditions
- Pregnancy Related, Mental Health Issue, Postpartum Depression, Postpartum Anxiety
- Trial name
- DDT (NCT06442774)
- Testing
- Mobile application, Monitoring via wearable
- Where
- 3 sites in Spain
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- A Thousand Colibris, S.L
Cigarette Smoking, Schizophrenia
Integrated Smoking Cessation Treatment for Smokers With Serious Mental Illness
The overall aim of this study is to test the effect of academic detailing (i.e. provider-level educational intervention focused on evidence-based smoking cessation treatment for those with psychiatric illness) and community…
- Conditions
- Cigarette Smoking, Schizophrenia, Bipolar Disorder, Depressive Disorder, Major
- Trial name
- NCT02845440
- Testing
- Academic Detailing, Community Health Worker, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 1,165 people
- Sponsor
- Massachusetts General Hospital
Caregivers
Mobile Technology and Data Analytics to Identify Real-time Predictors of Caregiver Well-Being
The purpose of this study is to test whether personalized messages from an easy-to-use mobile app improve mood and stress among care partners and to see if care partners like using the app.
- Trial name
- NCT04556591
- Testing
- Just-in-time adaptive intervention (JITAI), Control
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Arthritis, Diabetes
Can Mental Health Chatbots Help Chronic Disease Populations?
Past research has shown that patients suffering from chronic health conditions tend to experience high levels of negative mental health symptoms (e.g., depression).
- Conditions
- Arthritis, Diabetes, Depression, Anxiety
- Trial name
- NCT04620668
- Testing
- Wysa
- Where
- Canada
- Volunteers
- 79 people
- Sponsor
- Luke MacNeill
Anxiety, Depression
Implementation of WHO's Doing What Matters in Times of Stress in Dutch Small and Medium-sized Enterprises (SMEs)
The goal of this cluster randomized controlled trial is to explore if mental health in Dutch small and medium-sized enterprises (SMEs) can be improved by the World Health Organization's online program Doing What Matters in Times…
- Conditions
- Anxiety, Depression, Psychological Distress
- Trial name
- NCT06979089
- Testing
- Doing What Matters in Times of Stress
- Where
- Netherlands
- Volunteers
- 518 people
- Sponsor
- VU University of Amsterdam
Bipolar Disorder, Major Depressive Disorder
Evaluation of the Impact of the EDIT-B® Blood Test on the Health Status of Patients Presenting a Major Depressive Episode. Clinical Utility and Medico-Economic Aspects
Depression is one of the most common mental disorders, affecting nearly 10% of men and 20% of women worldwide. It is associated with a significant increase in mortality, mainly due to suicidal behavior.
- Trial name
- SEM EDIT-B (NCT06507787)
- Testing
- EDIT-B test, EDIT-B test (without giving result)
- Where
- 7 sites in France
- Volunteers
- 450 people
- Sponsor
- Alcediag
Mental Disorder in Adolescence, Depression in Adolescence
Adolescent Psychiatry Inpatients: Self-reported Parent-adolescent Communication Quality and Treatment Outcome
The quality of parent-adolescent communication has been found to be associated with adolescent mental health. However, little is known about the association of parent-adolescent communication and adolescent mental health in the…
- Conditions
- Mental Disorder in Adolescence, Depression in Adolescence, Anxiety
- Trial name
- NCT06633458
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Psychosocial Problem, Psychological Distress
Evaluating Impacts of CSS for Veterans and Their Families in Ukraine
This cluster-randomized controlled trial (c-RCT) evaluates the effectiveness of a brief, single-session psychosocial workshop, "CETA Short Session" (CSS), for reducing symptoms of distress and functional impairment and increasing…
- Conditions
- Psychosocial Problem, Psychological Distress, Engagement, Patient
- Trial name
- NCT04234815
- Testing
- CETA Short Session (CSS), Psychoeducation and Safety
- Where
- Ukraine
- Volunteers
- 1,193 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
SARS-CoV Infection, Anxiety
COVID-19-Related Health and Practices Among Dental Hygienists
As dental practices reopen their practices during a global pandemic, the risk of 2019 novel coronavirus (COVID-19) infection that dental hygienists face in providing dental care remains unknown.
- Conditions
- SARS-CoV Infection, Anxiety, Depression, Occupational Problems
- Trial name
- NCT04542915
- Testing
- No intervention
- Where
- United States
- Volunteers
- 6,976 people, healthy volunteers welcome
- Sponsor
- American Dental Association
Postnatal Depression
Effect of the 'Mother and Baby' Program on Well-Being
The study investigates the effect of the 'Mother and Baby' (M\&B) program on the psychological health and well-being of new mothers 6-10 weeks following the birth of their baby.
- Trial name
- NCT00361478
- Testing
- Exercise and education, Education
- Where
- Australia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
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