Clinical trials: Mental Health (Depression)
Intensive Care Unit Syndrome, Relatives
The Effectiveness of a Post-ICU Recovery Program on Relatives
Relatives of intensive care patients are at risk of developing symptoms of anxiety, depression and post-traumatic stress disorder resulting in impaired health-related quality of life (HRQOL).
- Trial name
- RAPIT-II (NCT03264365)
- Testing
- Intervention
- Where
- Denmark
- Volunteers
- 181 people
- Sponsor
- Holbaek Sygehus
Depression
Improving Mood in Veterans in Primary Care
The purpose of the Improving Mood in Veterans in Primary Care (IIR 14-047) is to evaluate a brief educational individual workshop that is meant to help Veterans better understand feelings of sadness and ways to improve their…
- Trial name
- NCT02276807
- Testing
- Brief Behavioral Activation, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 140 people
- Sponsor
- VA Office of Research and Development
Generalized Anxiety Disorder (GAD), Major Depressive Disorder (MDD)
Internet-Based Cognitive Behavioral Therapy With Treatment as Usual for Generalized Anxiety Disorder and Major Depressive Disorder in Taiwan (ICBT-TW)
This study aims to evaluate the effectiveness of internet-based cognitive behavioral therapy (ICBT) combined with treatment as usual (TAU) for adults diagnosed with generalized anxiety disorder (GAD) or major depressive disorder…
- Trial name
- ICBT-TW (NCT07177365)
- Testing
- Internet-Based Cognitive Behavioral Therapy (ICBT), Treatment as Usual (TAU) Only
- Volunteers
- 120 people
- Sponsor
- National Health Research Institutes, Taiwan
Preventive Intervention
Preventive Intervention to Promote Healthy Ageing
The aim of the project is the support of healthy ageing of older adults in acommunity. Efficient educational and psychosocial intervention will besuggested and verified to prevent anxiety, depression, and cognitivedisorders of…
- Trial name
- NCT05637177
- Testing
- Anging Wisely, Music therapy, Reminiscence therapy
- Where
- Czechia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Ostrava
Postnatal Depression, Mother-Infant Interaction
A Virtual Support Intervention for Postnatal Well-being
Postnatal depression (PND) and anxiety are significant public health concerns affecting a substantial proportion of new mothers worldwide.
- Trial name
- NCT06557200
- Testing
- Digital Infant- parents support
- Where
- Pakistan
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
MDD, Treatment Resistant Depression
Three Dosing Regimens of Dextromethorphan (DXM) Reportedly Used in Major Depressive Disorder
This is an open-label dosing pilot study of 15 patients aged 18-50 years of age with diagnoses of Major Depressive Disorder (MDD) randomized to 1 of 3 treatment arms.
- Conditions
- MDD, Treatment Resistant Depression, Smoking Cessation, Smoking
- Trial name
- NCT04226352
- Testing
- Dextromethorphan
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Johns Hopkins University
Cardiovascular Risk Factor, Diabetes Mellitus, Type 2
Evaluation of a Physical Activity Referral Scheme
The study will evaluate the effectiveness of a co-developed exercise referral scheme. Participants will be recruited to one of three groups 1. Co-developed exercise referral scheme, 2. Usual care exercise referral scheme, 3.
- Conditions
- Cardiovascular Risk Factor, Diabetes Mellitus, Type 2, Anxiety, Depression
- Trial name
- NCT03490747
- Testing
- Physical activity referral scheme, Usual care exercise referral scheme
- Where
- United Kingdom
- Volunteers
- 68 people
- Sponsor
- Paula Watson
Well-Being, Psychological, Depressive Symptoms
e-Intervention Enhancing Mental Health in Adolescents
The e-Intervention Enhancing Mental Health in Adolescents (IMPROVA) study will co-design, test, evaluate, and facilitate the upscaling of a modular eHealth intervention platform that aims to improve mental health and wellbeing…
- Conditions
- Well-Being, Psychological, Depressive Symptoms, Social Isolation
- Trial name
- IMPROVA (NCT06556576)
- Testing
- IMPROVA Platform
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Fundació Sant Joan de Déu
Anxiety Disorders and Symptoms, Depressive Symptoms
Using Machine Learning to Optimize User Engagement and Clinical Response to Digital Mental Health Interventions
Digital mental health interventions are a cost-effective and efficient approach to expanding the accessibility and impact of psychological treatments; however, little guidance exists for selecting the most effective program for a…
- Trial name
- NCT05567640
- Testing
- The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP), Space for depression, Space for resilience
- Where
- United States
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Depressive Symptoms
Audio-based Mental Health Intervention Study
This is a study on an audio-based digital intervention designed to reduce symptoms of depression. Participants who experience at least moderate symptoms of depression will be invited to participate in the study.
- Trial name
- NCT05555745
- Testing
- Audio-based behavioral activation intervention, Audio-based self-monitoring intervention
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Penn State University
Suicide, Suicide, Attempted
Suicide Prevention Among Recipients of Care
Randomized controlled trial to determine the best brief suicide prevention intervention for adults and adolescents who screen positive for suicidal ideation or behavior in emergency departments or primary care clinics.
- Conditions
- Suicide, Suicide, Attempted, Suicidal Ideation, Social Support
- Trial name
- SPARC (NCT04893447)
- Testing
- SPI+, SP+CC (Caring Contacts)
- Where
- United States
- Volunteers
- 1,520 people
- Sponsor
- St. Luke's Health System, Boise, Idaho
Depressive Symptoms, Anxiety Symptoms
Culturally Adapted i-CBT for Farsi/Dari Speaking Migrants
The aim of this randomized controlled trial (RCT) is to investigate the effectiveness of a culturally adapted internet-based cognitive behavioral therapy (i-CBT) intervention in reducing symptoms of common mental health issues…
- Conditions
- Depressive Symptoms, Anxiety Symptoms, Grief, Psychological Trauma
- Trial name
- i-CBT (NCT06828276)
- Testing
- Culturally adapted i-CBT
- Where
- Sweden
- Volunteers
- 128 people
- Sponsor
- Karolinska Institutet
Depressive Symptoms, Stress
Investigating Differential Effects of Online Mental Training Interventions on Mental Well-being and Social Cohesion
The SARS-CoV-2 pandemic, and the associated government-imposed isolationary lockdowns, has led to a mental health crisis on a global scale.
- Conditions
- Depressive Symptoms, Stress, Empathy, Compassion
- Trial name
- NCT04889508
- Testing
- Socio-emotional mental training, Mindfulness-based mental training
- Where
- Germany
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Max Planck Social Neuroscience Lab
Common Mental Disorders and/or Stress Related Symptoms
Stress and Mental Ill-health in the Workplace: Evaluation of an Intervention for the Prevention of Sick Leave
Purpose Common mental disorders (CMD:s) are the leading cause of sick-leave spells in Sweden, resulting in suffering for the individual and financial costs for the employer as well as for society at large.
- Trial name
- NCT02563743
- Testing
- Problem-solving based intervention, Treatment as usual
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska Institutet
Diagnosis, Psychiatric
Testing the Right Question Project (RQP) Health Education Strategy in a Mental Health Setting
The purpose of this pilot project is to test the effectiveness of three 20 minute health education modules on patient empowerment, patient activation and retention in care.
- Trial name
- RQP (NCT00134615)
- Testing
- RQP patient health education module
- Where
- 2 sites in United States
- Volunteers
- 231 people
- Sponsor
- Massachusetts General Hospital
Mindfulness, Depression
Internet-based Mindfulness-based Training (iMBT) for People With Depression
The research goals of this randomized controlled trial are to determine the feasibility and the mechanism of change of iMBT that has been developed using the Acceptance Checklist for Clinical Effectiveness Pilot Trials.
- Trial name
- NCT05410132
- Testing
- Internet-delivered Mindfulness Based Training (iMBT)
- Where
- Hong Kong
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Depression, Mental Health Issue
Digital Therapeutic Workplace Technology as a Employee Management Tool and Employee's Mental Health Care
The purpose of the study is to determine whether a digital healthcare app for employee's mental health can effectively improve the mental health of Hisbeans's employees and the managerial performance of Hisbeans, which is…
- Trial name
- NCT06295185
- Testing
- application MARO
- Where
- South Korea
- Volunteers
- 165 people
- Sponsor
- Ajou University School of Medicine
Stress - Prevention of Sleep Disorders, PTSD and Depression
Online Cognitive Behavioral Therapy (CBT) for Stress Disorders in Health Workers Involved in the Care of Patients During the Covid-19 Epidemic
Some preliminary epidemiological research conduct in China in health workers involved in the care of Covid-19 patients has shown high rates of depression (>50%), generalized anxiety disorder (>44%), insomnia (>36%) and stress…
- Trial name
- REST (NCT04362358)
- Testing
- Online cognitive behavioral therapy (CBT), Online bibliotherapy programme
- Where
- France
- Volunteers
- 156 people
- Sponsor
- University Hospital, Strasbourg, France
Depression, Anxiety
An Online Guided Self-help Intervention to Improve Common Mental Health Problems Among Medical Professionals
This randomized controlled trial (RCT) aims to evaluate the effectiveness of an online guided self-help intervention developed based on Problem Solving Therapy (PST) and Acceptance and Commitment Therapy (ACT), which are both…
- Trial name
- EMPOWER (NCT06910748)
- Testing
- E-training for Medical Professionals On Wellbeing and Effective Resolutions (E.M.P.O.W.E.R.), Education Materials
- Where
- Hong Kong
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Anxiety, Hospitalization
Virtual Nature Versus Guided Imagery for Anxiety and Well-Being in Hospitalized Older Adults
Long hospital stays can be difficult for older adults. Being confined to a ward, with limited mobility and little access to the outdoors, may contribute to anxiety, low mood, and reduced well-being.
- Conditions
- Anxiety, Hospitalization, Quality of Life, Psychological Distress
- Trial name
- NCT07765355
- Testing
- Immersive virtual reality nature exposure, Guided imagery
- Where
- 2 sites in Hungary
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
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