Clinical trials: Mental Health Disorders
Insomnia, Mental Health Functioning
Computerized Cognitive Behavioral Treatment for Insomnia: Improving Rural Veteran Access to Evidence-Based Treatment to Reduce Suicide Risk (R-Vets Sleep)
Insomnia is a major problem among veteran populations. Insomnia impacts physical and mental health functioning and is associated with reduced quality of life.
- Conditions
- Insomnia, Mental Health Functioning, Physical Health Functioning
- Trial name
- R-Vets Sleep (NCT03365024)
- Testing
- Computerized Cognitive Behavioral Therapy for Insomnia, Sleep Education
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Prostate Cancer, Erectile Dysfunction
A Bio-psychosocial Sexual Health Intervention for Prostate Cancer Survivors and Partners: a Feasibility Study
The burden of sexual dysfunction after prostate cancer surgery is responsible for the single greatest impact on patient/partner health-related quality of life; substantially more so than concern for cancer recurrence, or any…
- Conditions
- Prostate Cancer, Erectile Dysfunction, Sexual Dysfunction
- Trial name
- BSHR (NCT02640131)
- Testing
- Biomedical Component, Psychosocial Component, Attention Control
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- University Health Network, Toronto
Anxiety, Depression
Digital Single Session Intervention for Youth Mental Health
The aim of this study is to test the effectiveness of a single-session, digital intervention teaching the principle of practicing the opposite, when administered to youths on the waitlist for psychotherapy, with usual waitlist…
- Conditions
- Anxiety, Depression, Conduct Disorder, Stress
- Trial name
- NCT05449002
- Testing
- Practicing the Opposite (PTO), Usual Clinical Care
- Where
- 5 sites in United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Harvard University
Depressive Disorder, Pregnancy
EnBrace HR for Depression Treatment and Prevention in Women Trying to Conceive and Early Pregnancy
The purpose of this study is to assess the effectiveness of the EnBrace HR prenatal supplement in preventing depression in women with a history of depression who have decided to stop taking antidepressants during their pregnancy…
- Trial name
- NCT02676882
- Testing
- EnBrace HR
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital
Sleep Quality, Depression Disorders
The Relationship Between Power Sleep and Sleep Quality, Depression, and Stress Levels in University Students
This prospective cohort study aims to evaluate the effects of daily daytime power napping on sleep quality, depression, and perceived stress levels among healthy individuals.
- Conditions
- Sleep Quality, Depression Disorders, Stress, Psychological, Occupational Stress
- Trial name
- NCT07315269
- Testing
- Daytime Power Napping
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- okkes zortuk
Mental Health Issue
Effect of a Mental Wellness App on the Mental Wellness of Medical and Nurse Anesthesia Students
Mental health issues and suicide are becoming increasingly common among health care trainees and providers. Suicide is the leading cause of death among male medical residents and the second leading cause of death among female…
- Trial name
- NCT05925062
- Testing
- QActual
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Primary Biliary Cholangitis (PBC)
Using Digital Health Technology to Monitor Patients With Primary Biliary Cholangitis (PBC)
The purpose of this study is to explore the use of digital health technology for measuring symptoms and daily health in people with primary biliary cholangitis (PBC).
- Trial name
- NCT07631442
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Major Depressive Disorder
VA Augmentation and Switching Treatments for Improving Depression Outcomes
The overall purpose is to determine research based 'next-steps' for outpatients with major depressive disorder who have not had satisfactory outcomes to standard 'first-step' treatments.
- Trial name
- VAST-D (NCT01421342)
- Testing
- Switching: Bupropion-SR, Augmenting: Antidepressant + Bupropion-SR, Augmenting: Antidepressant + Aripiprazole
- Where
- 35 sites in United States
- Volunteers
- 1,522 people
- Sponsor
- VA Office of Research and Development
HIV, Tobacco Use
Optimizing Treatment of Co-occurring Smoking and Unhealthy Alcohol Use Among PWH in Nairobi, Kenya
People with HIV (PWH) smoke tobacco cigarettes and drink alcohol at higher rates than the general population, both in the US and internationally, including low- and middle-income countries.
- Conditions
- HIV, Tobacco Use, Alcohol Use Disorder
- Trial name
- NCT06790342
- Testing
- Cystine, Positively Smoke Free, Standard of Care
- Where
- 2 sites in Kenya
- Volunteers
- 300 people
- Sponsor
- University of Chicago
Sleep Bruxism, Adult, Stress
The Effect of Stress, Anxiety, and Depression Experienced by Pregnant Women on Sleep Bruxism and Oral Health
Background The oral health of pregnant women affects not only the systemic health of the mother but also the birth outcome of the fetus.
- Conditions
- Sleep Bruxism, Adult, Stress, Depression, Anxiety
- Trial name
- NCT06520241
- Testing
- Pregnant
- Where
- Turkey (Türkiye)
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- Trakya University
Pregnancy Complications, Mental Health Issue
Psychobiological Interventions in Pregnancy
This randomized control trial will evaluate whether a physical activity intervention can improve mental health and biologic markers of stress in pregnant people with depressive or anxiety symptoms.
- Conditions
- Pregnancy Complications, Mental Health Issue, Depression, Anxiety, Pregnancy, High Risk
- Trial name
- PIP (NCT06430853)
- Testing
- Step count goal, Actigraph watch
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Stanford University
Colostomy
Examining the Effectiveness of a Mobile App on Self-care for a Colostomy
Colorectal cancer has been one of the most common cancers in Taiwan. Using m-Health Apps to improve accessibility of personal health management has received greater attention and recognition.
- Trial name
- NCT05072379
- Testing
- colostomy self-care app
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cheng-Hsin General Hospital
Prodromal Schizophrenia, Psychosis
Feasibility Trial of a Lifestyle Intervention for CHR-P
The present study will assess the feasibility and social validity of an adjunctive health promotion group for youth and clinical high risk for psychosis (CHR-P).
- Conditions
- Prodromal Schizophrenia, Psychosis, Psychological Disorder, Psychological Stress
- Trial name
- NCT05532683
- Testing
- Health Behaviors Group
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of California, Los Angeles
Depressive Symptoms, Anxiety
Caring for Family Caregivers:a Research-action Study
The purpose of this study is to evaluate the effectiveness of the Problem Solving Technique (PST) in reducing symptoms of anxiety and depression among primary caregivers of chronically ill patients.
- Conditions
- Depressive Symptoms, Anxiety, Emotions
- Trial name
- NCT01786083
- Testing
- Application of Problem Solving Technique
- Where
- Spain
- Volunteers
- 122 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Iron Deficiency Anemia of Pregnancy
Adiposity and Iron Requirements in Pregnancy
This study aims to explore how body fat influences the response to either 25 or 50 mg of daily iron supplements during pregnancy.
- Trial name
- ADIPREG (NCT06425796)
- Testing
- Adiposity and Iron Requirements in Pregnancy (ADIPREG)
- Where
- 3 sites in United Kingdom
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Depression, Anxiety
SALSA (Health, Food and Sociability): Community Networks for Healthy Eating, Autonomy, and Social Interaction
Antecedents: Unwanted loneliness is associated with an increased risk of anxiety, depression, social isolation, and malnutrition.
- Conditions
- Depression, Anxiety, Social Support (Formal and Informal), Quality of Life (QOL)
- Trial name
- SALSA (NCT06800027)
- Testing
- SALSA group intervention: Going to lunch at the restaurant in a group and attending healthy eating workshops.
- Where
- Spain
- Volunteers
- 98 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Depression, Anxiety
Novel and Conventional Interventions for Cognitive and Emotional Flexibility in Patient Trauma
This study is testing whether combining a rapid form of transcranial magnetic stimulation (TMS), an oral medication called d-cycloserine (DCS), and therapy can improve brain flexibility and emotional control in adults…
- Conditions
- Depression, Anxiety, Trauma Patients
- Trial name
- NOCICEPT (NCT07868627)
- Testing
- D-Cycloserine (DCS), Transcranial Magnetic Stimulation, Unified Protocol
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Mclean Hospital
Work-Related Stress
Informal Caregivers at Work - Phase 2
Mental health problems are rising among children and adolescents. This may not only impact the child's level of daily functioning but also close family members.
- Trial name
- PPJob-II (NCT06441461)
- Testing
- Primary informal caregiver at work.
- Where
- Denmark
- Volunteers
- 4,386,647 people
- Sponsor
- Team Working Life Denmark
Healthy
Study Evaluating the Pharmacokinetics of Venlafaxine ER and Desvenlafaxine SR in Healthy Subjects
The purpose of this study is to determine if the relative difference in PK between extensive metabolizers (EMs) and poor metabolizers (PMs) is the same with desvenlafaxine SR and venlafaxine ER when a single dose is administered.
- Trial name
- NCT00329186
- Testing
- desvenlafaxine SR, venlafaxine ER
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Nocturnal Enuresis
A New Check-list Method for Nocturnal Enuresis
The study is aimed to demonstrate the benefits of newly formed written check-list of behavioral instructions and investigate its effects on parent's awareness, consciousness and motivation toward MNE.
- Trial name
- NCT03510975
- Testing
- desmopressin melt form 120 μg, Verbal behavioral therapy, Behavioral therapy with written check-list
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ankara Training and Research Hospital