Clinical trials: Mental Health Wellness 2
Healthy Smokers
Pilot Pharmacokinetic Study of New Nicotine Lozenge Formulations
The purpose of this study is to determine the pharmacokinetic profile of nicotine following a single oral administration of three new nicotine lozenge formulations (V0474) in comparison with two reference products.
- Trial name
- NCT01574898
- Testing
- V0474 - A mg, V0474 - B mg, V0474 - C mg
- Where
- France
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Medicament
Claustrophobia, Complication of Diagnostic Procedure
Comfort Talk and Economic Outcomes in MRI
Annually, an estimated 700,000 patients do not complete their scheduled MRI scans because of claustrophobia or inability to hold still.
- Trial name
- ComfortTalk® (NCT02427737)
- Testing
- Comfort Talk® Training
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- Hypnalgesics, LLC
Type 2 Diabetes Mellitus, Health Adult Subjects
Sleep Quality, Adiposity and Diet Quality
The aim of this study is to evaluate the effects of sleep quality on cardiovascular disease risk and food and nutrient intakes. Within the scope of this study, several parameters associated with cardiovascular disease risk will…
- Trial name
- Obesity (NCT07870122)
- Where
- Turkey (Türkiye)
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Type 2 Diabetes, Diabete Mellitus
Game-Based Education and Treatment Adherence in Type 2 Diabetes
The goal of this clinical trial is to learn if an education program can help lower anxiety and improve treatment follow-up in adults with type 2 diabetes.
- Trial name
- NCT07195188
- Testing
- "Let's Learn Diabetes" Game-Based Education, Traditional Diabetes Education
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Izmir Tinaztepe University
Mental Health Issue, Depression
Development and Validation of Psycho-Social Program (PSP)
The study aims to determine the effectiveness of a structured psycho-social program (PSP) in improving mental health outcomes among patients with Type 2 diabetes mellitus (T2DM).
- Conditions
- Mental Health Issue, Depression, Diabetes Distress, Quality of Life
- Trial name
- PSP-T2DM (NCT07456410)
- Testing
- Psycho-Social Program
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Government College University Faisalabad
Diabetes Mellitus, Type 2
DiaMester Pilot RCT: E-health Lifestyle Program for Type 2 Diabetes
This registration covers a pilot for a 3-armed parallel-group randomized controlled trial (RCT) that will evaluate the efficacy of DiaMester, a Norwegian e-health programme designed to improve self-management and induce…
- Trial name
- DiaMester (NCT07361640)
- Testing
- e-health lifestyle program, Low calorie diet
- Where
- Norway
- Volunteers
- 99 people
- Sponsor
- Oslo University Hospital
Anxiety
Web-based Single-session Growth Mindset Intervention for Allied Health Practicum Trainees to Reduce Anxiety
Practicum is a critical component of professional training, offering essential experiential learning opportunities that support the development of future practitioners.
- Trial name
- NCT07085897
- Testing
- Web-based Single-session Intervention of Mindset on Intelligence, Failure, and Emotion (We-SMILE) for allied health practicum trainees
- Volunteers
- 120 people
- Sponsor
- The Hong Kong Polytechnic University
Depression Anxiety Disorder
Hybrid Type 2 Implementation-Effectiveness Trial of a Third Wave Virtual Reality Treatment for Youth Depression/Anxiety
This research will evaluate a new virtual reality (VR) intervention to support youth with depression and anxiety. While VR has shown promise for adult mental health, little is known about its use in youth or routine clinical…
- Trial name
- NCT06894836
- Testing
- Third wave VR therapy
- Where
- Australia
- Volunteers
- 75 people
- Sponsor
- Orygen
Long COVID
Mental Intervention and Nicotinamide Riboside Supplementation in Long Covid
Long COVID, also referred to as post-acute sequela of COVID-19 (PASC), is present in a substantial number of individuals, and treatment for this is warranted.
- Trial name
- MINIRICO (NCT05703074)
- Testing
- Nicotinamide Riboside (NR), Mind-body reprocessing therapy (MBRT), Care as usual
- Where
- Norway
- Volunteers
- 310 people
- Sponsor
- University Hospital, Akershus
Substance Abuse
A Phased-Implementation Feasibility and Proof-of-Concept Study to Assess Incorporating the NIDA CTN Common Data Elements (CDEs) Into the Electronic Health Record (EHR) in Large Primary Care Settings ("CDE-EHR-PC" Study), Phase 2
This is a 4-phase study to implement the NIDA (Common Data Elements) Common Data Elements (CDEs) in primary care settings. The study will be conducted at three adult primary care clinics, in two large health systems.
- Trial name
- NCT02986841
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- NYU Langone Health
Diabetes Mellitus, Type 2, Depression, Anxiety
Interactive Virtual Assistance for Self-Care Management and Mental Health Promotion in Type 2 Diabetes
BACKGROUD: Health technology is an important tool in the aging process, which may improve the health condition and self-esteem of the elderly, in addition to offering new opportunities and challenges.
- Conditions
- Diabetes Mellitus, Type 2, Depression, Anxiety, Mental Health Disorder, Old Age; Debility
- Trial name
- NCT05329376
- Testing
- Smart Speaker Echo Dot, Usual Care
- Where
- Brazil
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Diabetes Type 2, Diabetes Type 1
Disentangling the Effect of Brain Insulin Resistance on Brain Health
People with diabetes are at increased risk of developing dementia, including Alzheimer's disease and vascular dementia. In addition, persons with diabetes have more pronounced age-related brain atrophy and cognitive difficulties…
- Trial name
- BIR 1 (NCT07374705)
- Where
- 3 sites in Denmark, Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Henrik Bo Wiberg Larsson
ADHD, Asperger Syndrome
A Prospective Observational Study of Family-based Interventions for Children With Neuropsychiatric and/or Psychiatric Disorders
The purpose of this study is to examine the feasibility and the effects of family-based interventions for children (aged 5-12) with neuropsychiatric and psychiatric disorders in Finnish health care settings.
- Conditions
- ADHD, Asperger Syndrome, Child Behavior Disorders
- Trial name
- NCT02250339
- Testing
- LAKU family program, Etä-LAKU family program, Family therapy
- Where
- Finland
- Volunteers
- 230 people
- Sponsor
- Social Insurance Institution, Finland
Psychological Flexibility, Psychological Distress
ACT-Based Counseling to Improve Psychological Flexibility in Mothers of Infants Hospitalized in the NICU
This randomized controlled trial will evaluate two Acceptance and Commitment Therapy (ACT)-based counseling approaches for mothers whose infants are hospitalized in a Neonatal Intensive Care Unit (NICU).
- Conditions
- Psychological Flexibility, Psychological Distress, Neonatal Intensive Care Unit, Acceptance & Commitment Therapy
- Trial name
- NICU-ACT (NCT07837609)
- Testing
- ACT-Based Online Psychoeducational Workshop, ACT-Based Chatbot Counseling
- Volunteers
- 135 people
- Sponsor
- Meserret Aslan
Type 2 Diabetes Mellitus (T2DM), Cognitive Impairment
Exercise and PPARGC1A rs8192678 in Older Adults With Type 2 Diabetes and Cognitive Impairment
This completed single-arm interventional study evaluated changes in metabolic control, cognitive function, and health-related physical fitness following a 12-week combined aerobic and resistance exercise program in older adults…
- Trial name
- Association Be (NCT07711834)
- Testing
- Combined aerobic and resistance exercise
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Harbin Sport University
Mental Health Issue, Mental Disorder
A Trial of Two Universal Programs for Parents of Teenagers
Group-based and internet-delivered parenting programs may help parents improve their communication and relationships with their children.
- Conditions
- Mental Health Issue, Mental Disorder, Adolescent Behavior, Adolescent Development
- Trial name
- NCT06366438
- Testing
- ABC-teen, ParentWeb
- Where
- 58 sites in Sweden
- Volunteers
- 1,247 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Health Behavior, Noncommunicable Diseases
The LvL UP Trial: Assessing the Effectiveness of a mHealth Intervention
Non-communicable diseases (NCDs), such as cardiovascular disease, diabetes, or cancer, and common mental disorders (CMDs), such as depression or anxiety, represent the primary causes of death and disability worldwide, causing…
- Conditions
- Health Behavior, Noncommunicable Diseases, Mental Health Issue, Lifestyle Risk Reduction
- Trial name
- NCT06592443
- Testing
- LvL UP, LvL UP + MI, Comparison
- Where
- 2 sites in Singapore
- Volunteers
- 1,061 people, healthy volunteers welcome
- Sponsor
- Singapore ETH Centre
Type2 Diabetes, Type 2 Diabetes Mellitus in Obese
Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)
Investigators propose to study youth across the spectrum of body mass index (BMI) and dysglycemia. This approach will allow investigators to disentangle the relationship of key features of type 2 diabetes (T2D) risk (e.g.
- Conditions
- Type2 Diabetes, Type 2 Diabetes Mellitus in Obese, Dysglycemia, Microvascular Complications
- Trial name
- Metabrain (NCT05277558)
- Testing
- Observational
- Where
- 2 sites in United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Opioid-use Disorder, Opioid Dependence
Comparing Two Training Methods for Opioid Wizard
The prevalence of opioid use disorder (OUD) and opioid-related deaths has risen dramatically in recent years. Effective treatments, including medications for opioid use disorder (MOUDs; e.g., buprenorphine-naloxone and methadone)…
- Conditions
- Opioid-use Disorder, Opioid Dependence, Attitude of Health Personnel
- Trial name
- NCT04867382
- Testing
- Online training
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- HealthPartners Institute
Diabetes Mellitus, Type 2, Nicotine Dependence, Cigarettes
Effect of Glucagon-like Peptide-1 (GLP-1) Receptor Agonist Stimulation on Smoking Consumption in Type 2 Diabetes Patients
Diabetes has become an increasingly serious global health issue. In 2024, approximately 537 million adults were living with diabetes, and this number is projected to rise to 783 million by 2045, representing a 46% increase.
- Trial name
- NCT06924697
- Testing
- Application of GLP-1RAs drugs, DPP-4i group
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Shanghai East Hospital