Clinical trials: Mental Illness
Treatment Satisfaction, Participation Rate, Patient
Mindfulness Based Stress Reduction for Intellectually Able Autistic Adults
This project evaluates mindfulness based stress-reduction (MBSR), adjusted and manualized for intellectually able autistic adults. MBSR is a skills training program based on further development of cognitive behavioral therapy.
- Conditions
- Treatment Satisfaction, Participation Rate, Patient, Quality of Life, Mental Illness
- Trial name
- NCT05244265
- Testing
- Mindfulness-based stress reduction (MBSR), Treatment as usual (TAU)
- Volunteers
- 140 people
- Sponsor
- Karolinska Institutet
Nicotine Dependence
Effectiveness of GW468816, an NMDA Glycine Site Antagonist, for Prevention of Relapse to Smoking
The purpose of this study is to evaluate the efficacy of the glycine antagonist, GW468816, compared with placebo on duration of abstinence and rates of relapse in recently quit female smokers in a randomized, double-blind…
- Trial name
- NCT00218465
- Testing
- GW468816
- Where
- 2 sites in United States
- Volunteers
- 264 people
- Sponsor
- Massachusetts General Hospital
Mental Health Wellness
Study of Probiotic Use After Childbirth in Relation to Emotional Well-Being
Researchers at Massachusetts General Hospital are interested in learning more about the neurobiology of well-being in new mothers and novel ways to support them during their transition to parenthood.
- Trial name
- PACE (NCT04472065)
- Testing
- Lactobacillus reuteri
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Elizabeth Austen Lawson
Trichotillomania, Hair Pulling
N-Acetylcysteine for Pediatric Trichotillomania
Trichotillomania (hair pulling) has an estimated lifetime prevalence of 1-3%. Children with trichotillomania can experience significant impairment due to peer teasing, avoidance of activities (such as swimming and socializing)…
- Trial name
- NCT00993265
- Testing
- N-Acetylcysteine
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Yale University
Alzheimer Disease
DORA and LP in Alzheimer's Disease Biomarkers
The purpose of this study is to see if the sleep aid, lemborexant, can decrease the amount of amyloid-beta and tau in the blood. Amyloid-beta and tau are proteins involved in the disease process leading to Alzheimer's disease.
- Trial name
- NCT06274528
- Testing
- Lemborexant 10 mg, Lemborexant 20mg
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Pregnant Women, Psychotropic Drugs
National Pregnancy Registry for Psychiatric Medications
The National Pregnancy Registry for Psychiatric Medications is dedicated to evaluating the safety of psychiatric medications such as antidepressants, ADHD medications, sedative hypnotics, and atypical antipsychotics that many…
- Trial name
- NCT01246765
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Effectiveness of Video Based Education Versus Music Therapy on Anxiety, Experience, and Co-operation Among Patients Undergoing Magnetic Resonance Imaging
Effectiveness of Video Based Education Versus Music Therapy on Anxiety, Experience, and Co-operation Among Patients Undergoing Magnetic Resonance Imaging in Radiology Department at ILBS, New Delhi.
A study to assess the Effectiveness of Video Based Education Versus Music Therapy on Anxiety, Experience, and Co-operation among Patients undergoing Magnetic Resonance Imaging.
- Trial name
- NCT04545086
- Testing
- Video Based Education, Music Therapy
- Where
- India
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Institute of Liver and Biliary Sciences, India
Breast Cancer, Locally Advanced Breast Cancer
Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer
This randomized, placebo-controlled trial aims to assess the feasibility, acceptability, and preliminary efficacy of memantine and the University of Carolina (UNC)'s Get Real \& Heel cancer exercise program (MEM+EX) in addressing…
- Conditions
- Breast Cancer, Locally Advanced Breast Cancer, Cognitive Impairment, Cognitive Decline
- Trial name
- NCT06727773
- Testing
- Memantine, Exercise Intervention, Exercise Control
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Covid19, Cognitive Impairment
The COGCOV Study in ICU Patients
Acute Respiratory Distress syndrome (ARDS) is a pulmonary systematic inflammatory response, leading to acute respiratory failure with hypoxia and/or hypercarbia.
- Trial name
- COGCOV (NCT04593069)
- Testing
- Neurocognitive assessment
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- Ziekenhuis Oost-Limburg
Gambling
Effects of Positive Psychological Group Psychotherapy and Auricular Acupressure on Withdrawal Symptoms
Objective The purpose of this study is to examine the effects of auricular acupressure and group counseling with positive psychology on gambling severity, withdrawal symptoms, and dopamine.
- Trial name
- NCT05241041
- Testing
- group counseling, auricular acupressure
- Where
- South Korea
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Inha University Hospital
Mild Cognitive Impairment, Alzheimer Disease
Causal Effect of Coenzyme Q10 Nutrition and Cognitive Dysfunction in the Metabolic Storm (Hyperglycemia and Sarcopenia) and Brain-derived Neurotrophic Factor
The aim of the study is to investigate the effects of coenzyme Q10 supplementation (150 mg twice daily; 300 mg/day for 12 weeks) on coenzyme Q10 status, glucose parameters, BDNF, myokines, and cognitive function in patients with…
- Conditions
- Mild Cognitive Impairment, Alzheimer Disease, Hyperglycemia, Pre-sarcopenia
- Trial name
- NCT06040905
- Testing
- Coenzyme Q10
- Where
- Taiwan
- Volunteers
- 51 people
- Sponsor
- Chung Shan Medical University
Alzheimer Disease
Enteric Nervous System in Alzheimer Disease
The close homology between the central and enteric nervous systems suggests that a disease process affecting the central nervous system could also involve its enteric counterpart.
- Trial name
- ENTEROMA (NCT02841605)
- Testing
- Rectosigmoidoscopy with colonic biopsies, Colonoscopy with colonic biopsies
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Nantes University Hospital
Anxiety, Medication-refractory Focal-onset Epilepsy
The Impact of Focused Ultrasound Thalamotomy of the Anterior Nucleus for Focal-Onset Epilepsy on Anxiety
The purpose of this study is to evaluate the feasibility, safety, and effects on anxiety of high intensity focused ultrasound ablation (FUSA) in patients suffering from treatment-refractory focal epilepsy and anxiety.
- Trial name
- NCT05032105
- Testing
- Magnetic Resonance Imaging-guided Focused Ultrasound Ablation (MRgFUSA)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Ohio State University
Elective Cesarean Section, Non Stress Test (NST)
Impact of White Noise and Stress Balls on Anxiety, Fetal Well-Being, and Surgical Fear in Elective Cesareans
This study aims to determine the effect of white noise and stress balls administered during NST on anxiety, fetal well-being, and fear of surgery in pregnant women scheduled for planned cesarean sections.
- Trial name
- Nonstrestest (NCT07276594)
- Testing
- only white noise, only stress ball, White noise + stress ball
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Agri Ibrahim Cecen University
Tobacco Dependence
Nicotine Lozenge or Tobacco-Free Snuff for Smokeless Tobacco Reduction
Smokeless tobacco (ST) is a known human carcinogen. Long-term ST use is known to increase the risk for oropharyngeal cancer. Extant literature on cigarette smokers suggests that smoking reduction increases smoking abstinence…
- Trial name
- NCT01018394
- Testing
- nicotine lozenges, tobacco-free snuff
- Where
- 2 sites in United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Child, Therapeutic Play
A Clown Accompanying Children During Blood Collection
Children may be exposed to acute and chronic illnesses during their development and may experience negative emotions and They may be exposed to experiences.
- Trial name
- NCT06252766
- Testing
- Experiment (Clown)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Necmettin Erbakan University
Personality Features in Anorexia Nervosa
Motivation to Change, Coping, and Self-Esteem in Adolescent Anorexia Nervosa
By use of several questionaires, this study aimed at an investigation of the changes in motivation, symptoms, self-esteem and coping style in adolescent patients with anorexia nervosa..
- Trial name
- NCT02828956
- Volunteers
- 92 people
- Sponsor
- University of Zurich
Depressive Disorder, Genetic Change
Association of Peripheral Immune Cells With Antidepressant Treatment Response
The purpose of this observational study is discovering potential biomarkers to predict antidepressant treatment response in patients with major depressive disorder (MDD) while comparing the transcriptomic changes between patients…
- Trial name
- NCT06182722
- Testing
- Mental assessments
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Alzheimer Disease, Dementia
Assistive Technology and Reduced Caregiver Burden
The study investigated a six-week randomized controlled trial study in a small cohort of 16 family caregivers of individuals living with Alzheimer's disease and related dementias.
- Conditions
- Alzheimer Disease, Dementia, Caregiver Burden, Quality of Life
- Trial name
- ck (NCT05352529)
- Testing
- The MapHabit system, Dementia educational videos
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- MapHabit, Inc.
Schizophrenia, HIV Infections
The Quality of Life of Patients With Severe Illnesses
Lately researchers and clinicians have emphasized the health related quality of life. Several reasons account for this trend. First of all, the advanced medical practices have contributed to the increased life expectancy.
- Trial name
- NCT00173329
- Where
- Taiwan
- Sponsor
- National Taiwan University Hospital
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