Clinical trials: Mental Illness
Autism Spectrum Disorder
Cognoa Autism Spectrum Disorder (ASD) Digital Therapeutic Engagement and Usability Study
Cognoa will measure usability, engagement with the device, and changes in parent-reported socialization during a 4-week period of intervention at home with the Cognoa ASD therapeutic device.
- Trial name
- NCT04326231
- Testing
- Usability assessment of Cognoa ASD Therapeutic Device
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cognoa, Inc.
Tobacco Use Disorder
Fresh Lime Alone for Smoking Cessation
The purpose of this study is to determine whether fresh lime alone is effective for smoking cessation.
- Trial name
- LIM (NCT01333202)
- Testing
- Fresh lime
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Thai Health Professional Alliance Against Tobacco
Tic Disorder, Childhood, Comorbidities and Coexisting Conditions
Improving Symptom Trajectories of Tic Disorders and Co-occurring Diagnoses: The Role of Integrative Intensive Intervention
The purpose to the current study was to examine the efficacy of a telehealth, group-based, combined and intensive intervention for youth with tic disorders (TDs) and common co-occurring diagnoses.
- Trial name
- NCT04878302
- Testing
- Combination of Comprehensive Behavioral Intervention for Tics (CBIT) and Evidence-based interventions for co-occurring diagnoses (i.e., Cognitive Behavioral Therapy, Behavioral Parent Training)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Florida International University
Depressive Disorder
Imaging to Improve Brain Stimulation
This study investigates how brains change as a result of a treatment for depression called repetitive transcranial magnetic stimulation (rTMS).
- Trial name
- NCT04016402
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- VA Office of Research and Development
Cognition Disorders in Old Age, Dementia
The "Motoric Cognitive Risk" Syndrome in the Quebec Population
The overall objective of the proposal is to examine the epidemiology of the newly reported "motoric cognitive risk" (MCR) syndrome, which is a pre-dementia syndrome combining subjective cognitive complaint (i.e.; memory…
- Trial name
- NCT03633253
- Testing
- Summarize of participants' characteristics using means and standard deviations or frequencies and percentages
- Where
- Canada
- Volunteers
- 1,741 people, healthy volunteers welcome
- Sponsor
- Jewish General Hospital
Cognitive Dysfunction, Critical Illness
Trauma and Critical Care Exposure Examined With PET (TRAPETS)
The overall aim is to examine the impact of trauma and critical illness on the brain, peripheral immune system and cognition. This is a prospective study where a study group exposed to trauma and intensive care will be be…
- Conditions
- Cognitive Dysfunction, Critical Illness, Trauma
- Trial name
- TRAPETS (NCT05245253)
- Testing
- Positron Emission tomography
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Karolinska University Hospital
Coronary Artery Disease, Diabetes Mellitus, Type 2
PIPAF Platelets in the Pathogenesis of Ageing Associated Frailty
This is a prospective observational study aimed at testing the existence of an association between frailty, inflammatory status, and degree of platelet activation and reactivity in elderly subjects with type 2 diabetes or…
- Conditions
- Coronary Artery Disease, Diabetes Mellitus, Type 2, Alzheimer Disease
- Trial name
- PIPAF (NCT05798637)
- Testing
- Standard of care
- Where
- 2 sites in Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera di Perugia
Spinal Cord Injury
Study of an Implantable Functional Neuromuscular Stimulation System for Patients With Spinal Cord Injuries
OBJECTIVES: I. Establish the procedures for implementing and assessing the clinical utility of functional neuromuscular stimulation using an implanted eight-channel standing and transfer system in patients with incomplete…
- Trial name
- NCT00004445
- Testing
- Surgery, IRS-8
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- Case Western Reserve University
Anesthesia, Surgery
General Versus Regional Anesthesia and Postoperative Sleep Quality
Major surgery can lead to postoperative disturbances in sleep patterns with subjective deterioration of sleep quality according to patients' reports as well as objective alterations of sleep architecture, as recorded by…
- Conditions
- Anesthesia, Surgery, Sleep Disturbance, Sleep Disorder
- Trial name
- AnesthSleep (NCT03843645)
- Testing
- general anesthesia, regional anesthesia
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Aretaieion University Hospital
Erectile Dysfunction, Renal Transplant
Extracorporeal Shockwave Therapy in the Treatment for Erectile Dysfunction in Male Renal Transplant Recipients
The primary objective of this study is to determine the impact of the shock wave application in renal transplant patients with diagnosis of erectile dysfunction.
- Trial name
- NCT02412345
- Testing
- Extracorporeal shockwave therapy, Penile ultrasound Doppler with intracavernosal injection application 20 mcg alprostadil
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Obsessive-compulsive Disorder
D-Cycloserine as an Adjunct to Internet-CBT for OCD
The purpose of this study is to examine if D-Cycloserine is an effective adjunct to internet-based cognitive behaviour therapy for patients with obsessive-compulsive disorder.
- Trial name
- NCT01649895
- Testing
- D-Cycloserine
- Where
- Sweden
- Volunteers
- 128 people
- Sponsor
- Christian Rück
ADHD, Predominantly Inattentive Type
Safety and Tolerability Study of Metadoxine Extended Release (MDX) (Previously Known as MG01CI) in PI-ADHD Adolescent Subjects
The purpose of this study is to evaluate the safety and tolerability of a single administration of Metadoxine Extended Release (MDX) formulation for the treatment of adolescents diagnosed with ADHD that have predominantly…
- Trial name
- NCT02189772
- Testing
- Metadoxine extended release
- Where
- 6 sites in Israel
- Volunteers
- 83 people
- Sponsor
- Alcobra Ltd.
Anxiety, Depression Disorders
Enhanced Ward Rounds and Communication for Pre-procedural Anxiety in GI Endoscopy Patients
This study tests a new way to help reduce anxiety in hospitalized patients waiting for therapeutic gastrointestinal (GI) endoscopy procedures, like EMR or ESD.
- Conditions
- Anxiety, Depression Disorders, Sleep Wake Disorders, Gastrointestinal Diseases
- Trial name
- NCT07286877
- Testing
- Enhanced Ward-Round Frequency With Standardized Communication, Usual Care Ward Rounds (2/day)
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- LanZhou University
Major Depressive Disorder
Neuroimaging Study of Bupropion Treatment in Patients With Major Depressive Disorder
The current study is being conducted in patients with major depression. The study aims to 1) investigate the combined effects of selective serotonin reuptake inhibitor (SSRI) and bupropion compared to SSRI alone on the…
- Trial name
- NCT01541475
- Testing
- Bupropion, Escitalopram, Escitalopram
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Ewha Womans University
Alzheimer's Disease
Evaluating Liraglutide in Alzheimer's Disease
This is a 12-month, multicentre randomised double-blind placebo-controlled Phase IIb study in patients with mild Alzheimer's dementia (AD). Patients will be randomised on a 1:1 ratio to receive liraglutide or matching placebo.
- Trial name
- ELAD (NCT01843075)
- Testing
- Liraglutide
- Where
- United Kingdom
- Volunteers
- 204 people
- Sponsor
- Imperial College London
ADHD, Deficits in Motor Control and Perception
Effectiveness of Technology-based Interventions for the Improvement of Cognitive Processes in ADHD.
To scientifically demonstrate the improvements in cognitive functions and core symptoms of children and adolescents diagnosed with ADHD through the implementation of a cognitive rehabilitation program based on the use of the most…
- Trial name
- NCT06477575
- Testing
- neurocognitive therapy based on new technologies, conventional neurocognitive therapy
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Extremadura
Social Cognition in Patients With Schizophrenia
Treating Social Cognition With Theta Burst Stimulation: a Multicentric Study
The purpose of the study is to test a new treatment of social cognition deficits in patients with schizophrenia or schizoaffective disorder by transcranial magnetic stimulation (theta-burst).
- Trial name
- TBS-COG (NCT02479919)
- Testing
- Magstim® Active TBS
- Where
- 3 sites in France
- Volunteers
- 61 people
- Sponsor
- University Hospital, Caen
Bipolar Disorder, Major Depressive Disorder
Reducing Suicide Risk in Adolescents and Young Adults Via a Psychobehavioral Intervention to Regularize Daily Rhythms
The purpose of this study is to advance a non-pharmacologic suicide preventive intervention with wide dissemination potential as an innovative high-yield solution to reduce suicide rates.
- Conditions
- Bipolar Disorder, Major Depressive Disorder, Mood Disorders, Suicide
- Trial name
- NCT05317481
- Testing
- BE-SMART-DR, psychoeducational control comparator condition (CC)
- Where
- 2 sites in United States
- Volunteers
- 65 people
- Sponsor
- Yale University
Autism Spectrum Disorder
PEACE for ImPACT Study
Investigators will test the impact of the PEACE implementation toolkit and determine the level of implementation support needed to improve early intervention providers use of caregiver coaching with families of young children…
- Trial name
- NCT06374381
- Testing
- PEACE Online Resources, PEACE Weekly Group Facilitation, PEACE Weekly Individual Facilitation
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Schizophrenia
Linagliptin in Schizophrenia Patients
Approximately one third of patients with schizophrenia show a poor response to standard treatment with antipsychotic medications.
- Trial name
- NCT01943019
- Testing
- Linagliptin
- Where
- Malaysia
- Volunteers
- 1 people
- Sponsor
- Monash University
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