Clinical trials: Mental Illness
Pain, Postoperative, Surgical Procedures, Operative
Postoperative Pain in Adult Patients.
Each surgical intervention associated with even a minor tissue injury is a source of pain which needs to be effectively controlled.
- Trial name
- NCT03731039
- Testing
- Observational study
- Where
- Poland
- Volunteers
- 620 people
- Sponsor
- Andrzej Frycz Modrzewski Krakow University
Emotional Disorder, Anxiety Disorders
The Unified Protocol for the Treatment of Emotional Disorders in Spanish Public Mental Health System
The present randomized, controlled trial will compare the cost-efficacy and acceptability of the Unified Protocol in group format against traditional individual Cognitive Behavioral Treatment in a sample of patients with…
- Conditions
- Emotional Disorder, Anxiety Disorders, Depressive Disorder
- Trial name
- NCT03064477
- Testing
- Unified Protocol, Cognitive Behavioral Therapy (TAU)
- Where
- 3 sites in Spain
- Volunteers
- 200 people
- Sponsor
- Universitat Jaume I
Virtual Reality, Children and Adolescents
Evaluation of the Efficacy of a Virtual Reality When Placing a Needle on an Implantable Venous Access Device in Children With Leukemia
Main objective: Evaluate the effectiveness of the repeated use of interactive or hypnotic virtual reality compared to standard treatment, on pain, during each needle placement on PAC for 3 months on children or adolescents (6 to…
- Conditions
- Virtual Reality, Children and Adolescents, Acute Leukemia, Anxiety and Fear
- Trial name
- LEAVE (NCT06697275)
- Testing
- Hypnotic Virtual reality, Interactive virtual reality, Standard method
- Where
- 4 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Clermont-Ferrand
Depression, Anxiety Disorders
Toward Understanding Drivers of Patient Engagement With Digital Mental Health Interventions - Part II
This study is a clinical trial that evaluates what drives patient engagement and tests the impact of two strategies-automated motivational push messaging and coach support-to improve engagement with an evidence-based mobile app…
- Trial name
- jq830 (NCT05555875)
- Testing
- SilverCloud
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Brigham and Women's Hospital
Posttraumatic Stress Disorder (PTSD)
Veterans Individual Placement and Support Towards Advancing Recovery
The primary objective of CSP#589 VIP-STAR is to evaluate the effectiveness of Individual Placement \& Support (IPS) in unemployed Veterans with PTSD.
- Trial name
- VIP-STAR (NCT01817712)
- Testing
- Individual Placement & Support, VA Transitional Work Program
- Where
- 13 sites in United States
- Volunteers
- 541 people
- Sponsor
- VA Office of Research and Development
Substance Use Disorders, Recidivism
Preventing OUD in Justice-Involved Youth
The United States is experiencing an opioid epidemic. Sadly, opioid-related fatalities are on the rise, causing profound emotional, financial, and cultural impacts.
- Trial name
- POST (NCT04901312)
- Testing
- Adolescent Community Reinforcement Approach, Assertive Continuing Care, Trauma Affect Regulation Guide for Education and Therapy
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- Seattle Children's Hospital
Borderline Personality Disorder
PILOT Phase: BPD Study
This pilot study aims to identify the area of the brain best suited for the treatment of Borderline Personality disorder (BPD). The study investigators will test whether repetitiveTranscranial Magnetic Stimulation (rTMS), a…
- Trial name
- NCT07223619
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Opioid Use Disorder
Identifying Optimal Buprenorphine Dosing for Opioid Use Disorder Treatment and Prevention of Overdose
The investigators aim to test the effectiveness of a high maintenance daily dose of buprenorphine (24 mg) for improving outcomes among patients who used fentanyl compared to the standard daily dose (16 mg).
- Trial name
- Optimal Bup (NCT06316830)
- Testing
- Buprenorphine
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Rhode Island Hospital
Stress, Pregnancy
Effect of Depression, Anxiety and Stress Scores on Embryo Transfer Success
Psychological status of couples attending to IVF programmes is important due to possible effect on final result. Observers aim to investigate the depression, anxiety and stress scores of couples before and after the procedure.
- Trial name
- NCT05681130
- Testing
- questionaire
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Eurofertil IVF Health Center
Attention-deficit Hyperactivity Disorder
A Trial to Assess the Pharmacokinetics, Safety, and Tolerability of Centanafadine Capsules in Pediatric Subjects With Attention-deficit Hyperactivity Disorder
This is a phase 1b, multicenter, open-label, multiple-dose trial in pediatric subjects (4 - 12 years of age, inclusive) with a confirmed diagnosis of ADHD.
- Trial name
- NCT04786730
- Testing
- Centanafadine
- Where
- 5 sites in United States
- Volunteers
- 50 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Mild Cognitive Impairment
Exergame Balance Training for Patients With Mild Cognitive Impairment
This study will be a randomized control trial, which will be conducted on older adults with mild cognitive impairment. A specially designed Exergame balance training will be used for cognitive enhancement in patients with MCI.
- Trial name
- NCT04959383
- Testing
- Low complexity Exergaming group, Moderate complexity Exergaming group, High complexity Exergaming group
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Riphah International University
Tourette's Disorder, Insomnia
Forehead Temperature-Regulating Therapy for Insomnia in Adults With Tourette's Disorder
The primary aim of the present research project is to investigate the preliminary effects of four weeks of forehead temperature-regulating therapy on insomnia in adults with Tourette's disorder and co-occurring insomnia disorder.
- Trial name
- NCT05499741
- Testing
- Forehead Temperature-Regulating Therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder, Autism
Oral Health Care in Autism Spectrum Disorder
Persons with autism spectrum disorder (ASD) are characterized by impairments in social interactions, speech and communication, restricted patterns of behaviour, and unusual sensory sensitivities.
- Trial name
- CREASED (NCT03830541)
- Testing
- Oral care delivery analysis in participants with ASD
- Volunteers
- 52 people
- Sponsor
- University of Novi Sad
Attention Deficit Hyperactivity Disorder, Depressive Symptoms
School-Based Depression Prevention for Adolescents With ADHD
The purpose of this study is to develop a modified behavioral activation program in adolescents with ADHD to be implemented by school mental health providers in an urban, low-income school district.
- Trial name
- BEAMS (NCT04104841)
- Testing
- Behaviorally Enhancing Adolescents' Mood in Schools, Usual Care
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Maryland, College Park
Parkinson Disease, Sleep Fragmentation
Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease
Parkinson's disease (PD) is a neurodegenerative disorder that leads to both motor and non-motor symptoms. Therapies have been developed that effectively target the motor symptoms.
- Trial name
- NCT04620551
- Testing
- Sub-clinical stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Nebraska
Schizophrenia
Observation of Change in Clinical Global Impression Scores in Schizophrenia Patients Receiving Seroquel XR Treatment
The purpose of this study is to assess severity of illness in schizophrenia patients in routine clinical practice at the time of entry in the study and after the treatment with Seroquel XR for 8 weeks.
- Trial name
- NCT00758251
- Where
- 15 sites in Latvia
- Volunteers
- 80 people
- Sponsor
- AstraZeneca
Sexual; Sexual Desire, Illicit Drugs
Chemsex, Perceived Risks and Coping Strategies.
The research hypothesis is that access to prevention and harm and risk reduction associated with the use of psychoactive substances in a sexual context is insufficient for MSM practicing chemsex.
- Conditions
- Sexual; Sexual Desire, Illicit Drugs, MSM
- Trial name
- Chemsex (NCT04584229)
- Testing
- Intervention
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Montpellier
Obsessive Compulsive Disorder (OCD)
Cognitive Behavioral Strategies and Transcranial Magnetic Stimulation in Obsessive-Compulsive Disorder: Open Label Study
The purpose of this study is to evaluate the effectiveness of repetitive TMS (rTMS) delivered simultaneously with elements of cognitive behavioral therapy/exposure-response prevention (CBT/ERP) in adult subjects (greater or equal…
- Trial name
- CBT-TMS (NCT02528331)
- Testing
- Transcranial magnetic stimulation, Cognitive behavioral therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Duke University
Alcohol Use Disorder
Brief Motivational Therapy Versus Usual Care for Alcohol Use Disorders in Primary Care.
Harmful alcohol use is a leading cause of global disability and death. However increased detection and brief intervention capacity of more severe alcohol use disorders (AUD) has not been accompanied by increased availability of…
- Trial name
- NCT04345302
- Testing
- Brief motivational treatment, Enhanced Usual Care
- Where
- 3 sites in Chile
- Volunteers
- 182 people
- Sponsor
- Nicolás Barticevic
Learning Disabilities, Behavioural Problem
Transforming Care Experiences of Support Workers and Managers
What research question is being addressed? What is the experience of support workers, and managers, supporting people with learning disabilities who have moved from inpatient to community settings as part of the Transforming Care…
- Trial name
- NCT06508853
- Testing
- Qualitative research (no intervention)
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- King's College London
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