Clinical trials: Mental Illness
Cocaine Dependence
Efficacy of Caffeine, With and Without Biperiden, as a Maintenance Treatment for Cocaine Dependence
The aim of this study is to assess the efficacy of caffeine compared to placebo as a maintenance treatment for cocaine dependence. Caffeine potentiation with biperiden will be also studied.
- Trial name
- NCT00495183
- Testing
- caffeine, Biperiden
- Where
- Spain
- Volunteers
- 108 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Disruptive Behavior Disorders
Technology to Enhance Treatment for Early Conduct Problems in Low Income Families
This study aims to the test the efficacy and cost effectiveness of new service delivery methods to enhance the reach and impact of the standard of care treatment, Behavioral Parent Training (BPT), for early onset disruptive…
- Trial name
- TE-HNC (NCT02191956)
- Testing
- Behavioral Parent Training
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- University of North Carolina, Chapel Hill
Autism Spectrum Disorder
Care Pathway for Children With Autism Spectrum Disorder Included in the ELENA Cohort
Autism Spectrum Disorder (ASD) is lifelong neurodevelopmental disorder that affect social communication and interaction and includes limited and repetitive patterns of behavior (DSM 5).
- Trial name
- ELENA-SNDS (NCT04292522)
- Where
- France
- Volunteers
- 903 people
- Sponsor
- University Hospital, Montpellier
Anxiety
Pre-procedural Anxiety and Sedation.
Colonoscopy is an outpatient procedure performed frequently as a screening test for diagnosis and treatment of a wide range of gastrointestinal problems.
- Trial name
- NCT01958151
- Testing
- State-Trait Anxiety Inventory Scores
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Basak Ceyda MECO
Binge Eating Disorder
Dialectical Behavioral Therapy As A Therapeutic Tool In Patients With Binge Eating Disorder
Binge eating disorder (BED) is one of the recently acknowledged eating disorders, with many theories underlying its pathology whether biological or psychological.
- Trial name
- NCT05560529
- Testing
- DBT, TAU, Plasma Ghrelin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Schizophrenia
The Effect of a Weight Management Program During Treatment With Olanzapine
The study is a prospective, randomized, open-label study.
- Trial name
- NCT00169702
- Testing
- weight management program
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Severe Mental Illness, Severe Mental Disorder
Outcome of Patients With Severe Mental Illness in the Intensive Care Unit
Severe mental illnesses (SMIs), such as major depression, schizophrenia, and bipolar disorder, carry a significant prevalence among patients admitted to the intensive care unit (ICU), estimated at an average of 19%.
- Trial name
- REPSYRE (NCT07705802)
- Testing
- Observational follow-up
- Where
- 30 sites in France
- Volunteers
- 2,000 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Perinatal Depression, Breastfeeding
The Relationship Between Maternal Perinatal Depression and Feeding Behavior Among Primiparas
The goal of this observational study is to explore the impact of pregnancy depression on infant feeding, and to explore the two-way relationship between postpartum depression and infant feeding.
- Conditions
- Perinatal Depression, Breastfeeding, Complementary Feeding
- Trial name
- NCT06231602
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Major Depressive Disorder
Semaglutide for the Treatment of Cognitive Dysfunction in Major Depressive Disorder
This study will examine whether semaglutide may improve cognitive function in individuals with major depressive disorder (MDD).
- Trial name
- NCT04466345
- Testing
- Semaglutide
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- University Health Network, Toronto
Anxiety Disorders, Mindfulness
The Impact of Mindfulness-Based Psychoeducation on Perceived Stress, Intolerance of Uncertainty, and Cognitive Flexibility in Patients With Anxiety Disorders
Mindfulness-based interventions, which cultivate the capacity to remain present with difficult thoughts and emotions and to maintain psychological well-being in the face of such challenges, have been shown to facilitate positive…
- Conditions
- Anxiety Disorders, Mindfulness, Perceived Stress, Intolerance of Uncertainty
- Trial name
- Anxiety (NCT07299045)
- Testing
- Mindfulness-Based Psychoeducational Program
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Aydin Adnan Menderes University
Schizophrenia
Effect of Lu AF35700 in Patients With Treatment-resistant Schizophrenia
To evaluate the efficacy of 10 and 20 mg/day of Lu AF35700 on schizophrenia symptoms in patients with treatment-resistant schizophrenia (TRS)
- Trial name
- DayBreak (NCT02717195)
- Testing
- Risperidone, Olanzapine, Lu AF35700
- Where
- 147 sites in United States, Bulgaria and 12 more
- Volunteers
- 1,098 people
- Sponsor
- H. Lundbeck A/S
Depression
Effectiveness of Culturally Based Congruent Care in Treating Hispanics With Major Depressive Disorder
This study will develop and evaluate the effectiveness of a culturally based program that aims to facilitate entry, retention, and successful treatment in specialized mental health services for Hispanics with major depressive…
- Trial name
- NCT00247195
- Testing
- Culturally Congruent Assessment and Treatment
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- New York State Psychiatric Institute
Alzheimer's Disease, Dementia
Safety and Efficacy of Divalproex and Quetiapine in Elderly Alzheimer's Dementia Patients
The primary aim is to determine whether Divalproex ER or one of the atypical antipsychotics is more effective improving dementia related behavioral symptoms in patients with dementia, and evaluate the impact of such improvements…
- Conditions
- Alzheimer's Disease, Dementia, Behavioral Symptoms
- Trial name
- NCT00375557
- Testing
- Divalproex ER, Quetiapine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Cincinnati
Dementia With Lewy Bodies
Effects of Nucleus Basalis of Meynert Stimulation on Cognitive Disorders in Dementia With Lewy Bodies
Deep brain stimulation has been developed as a substitute for the classical lesioning methods previously used in stereotactic and functional neurosurgery.
- Trial name
- DEMENSTIM (NCT01340001)
- Testing
- Electrical stimulation of the nucleus basalis of Meynert
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Rouen
Major Depressive Disorder (MDD)
Efficacy and Safety of Transcranial Temporal Interference Stimulation for Depression
The goal of this clinical trial is to learn whether transcranial temporal interference stimulation (tTIS) can help treat major depressive disorder (MDD) in adults.
- Trial name
- NCT07612501
- Testing
- Active Transcranial Temporal Interference Stimulation Targeting Left ALIC, Active Transcranial Temporal Interference Stimulation Targeting Left sgACC
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Yonggui Yuan
Bipolar Disorder, Major Depression
Effectiveness of mHealth Post-discharge Intervention for Patients With Severe Mental Illness
The overall aim of this program of research is to improve the continuity of care for patients with serious mental illness (SMI) by supporting a safer and more efficient bridge from hospital to outpatient care using a mobile…
- Conditions
- Bipolar Disorder, Major Depression, Schizophrenia
- Trial name
- tFOCUS (NCT05703412)
- Testing
- Transition-FOCUS mHealth Intervention, Check-In
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Butler Hospital
Opioid Use Disorder
Mobile Peer Support for OUD Recovery
The COVID-19 pandemic puts individuals recovering from opioid use disorders (OUDs), an already vulnerable population, at increased risk of overdose due to decreased access to treatment, decreased social support, and increased…
- Trial name
- MPS (NCT05405712)
- Testing
- Mobile Phone App
- Where
- 2 sites in United States
- Volunteers
- 1,300 people
- Sponsor
- Brown University
Anxiety State
Evaluation of an Anxiety Reduction Tool During Thyroid Biopsies
Patients undergoing thyroid biopsy under local anesthetic will be asked to fill out a questionnaire that evaluates their anxiety level before and after their procedure.
- Trial name
- NCT06358612
- Testing
- Stress Balls
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Nova Scotia Health Authority
Psychiatric Disorders
Psychiatric Disorders in Addiction - Interest of Screening and Influence on Relapse
In complex detoxification hospital units, patients receive a common care system (interviews, therapeutic workshops, support for discharges, etc.).
- Trial name
- Psyaddict (NCT07023419)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Parkinsons Disease (PD), Anxiety
TMS in Anxiety-Parkinson's Disease
Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's dementia. Anxiety in PD is common, has major effects on quality of life and contributes to increased disability.
- Trial name
- NCT06999330
- Testing
- Theta burst stimulation active coil
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- HealthPartners Institute
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